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Select item 70571231.

Modification effect of sex and obesity on the correlation of LEP polymorphisms with leptin levels in Taiwanese obese women

De‐Min Duan, Jing‐Yi Jhang, Semon Wu, Ming‐Sheng Teng, Lung‐An Hsu, Yu‐Lin Ko

Mol Genet Genomic Med. 2020 Mar; 8(3): e1113. Published online 2020 Jan 8. doi: 10.1002/mgg3.1113

PMCID:: PMC7057123

Abstract Article PDF–701K

Select item 70271952.

Systematic Nucleotide Exchange Analysis of ESTs From the Human Cancer Genome Project Report: Origins of 347 Unknown ESTs Indicate Putative Transcription of Non-Coding Genomic Regions

Ganesh Warthi, Pierre-Edouard Fournier, Hervé Seligmann

Front Genet. 2020; 11: 42. Published online 2020 Feb 11. doi: 10.3389/fgene.2020.00042

PMCID:: PMC7027195

Abstract Article PDF–1.2M

Select item 70102253.

A novel loop-mediated isothermal amplification method for efficient and robust detection of EGFR mutations

Sho Horiuchi, Yuichi Saito, Atsuka Matsui, Nobumasa Takahashi, Tomohiko Ikeya, Eishin Hoshi, Yoshihiko Shimizu, Masanori Yasuda

Int J Oncol. 2020 Mar; 56(3): 743–749. Published online 2020 Jan 14. doi: 10.3892/ijo.2020.4961

PMCID:: PMC7010225

Abstract Article PDF–672K

Select item 70045334.

Epidermal growth factor receptor mRNA expression: A potential molecular escape mechanism from regorafenib

Satoshi Matsusaka, Diana L. Hanna, Yan Ning, Dongyun Yang, Shu Cao, Martin D. Berger, Yuji Miyamoto, Mitsukuni Suenaga, Shingo Dan, Tetsuo Mashima, Hiroyuki Seimiya, Wu Zhang, Heinz‐Josef Lenz

Cancer Sci. 2020 Feb; 111(2): 441–450. Published online 2020 Jan 27. doi: 10.1111/cas.14273

PMCID:: PMC7004533

Abstract Article PDF–392K

Select item 69784025.

LncRNA DLX6‐AS1 increases the expression of HIF‐1α and promotes the malignant phenotypes of nasopharyngeal carcinoma cells via targeting MiR‐199a‐5p

Bin Yang, Lin Jia, Hui Ren, Caibao Jin, Qingrong Ren, Haiyuan Zhang, Desheng Hu, Hao Zhang, Liu Hu, Tao Xie

Mol Genet Genomic Med. 2020 Jan; 8(1): e1017. Published online 2019 Nov 29. doi: 10.1002/mgg3.1017

PMCID:: PMC6978402

Abstract Article PDF–1.2M

Select item 69782396.

Extensive genic and allelic heterogeneity underlying inherited retinal dystrophies in Mexican patients molecularly analyzed by next‐generation sequencing

Juan C. Zenteno, Leopoldo A. García‐Montaño, Marisa Cruz‐Aguilar, Josué Ronquillo, Agustín Rodas‐Serrano, Luis Aguilar‐Castul, Rodrigo Matsui, Carlos I. Vencedor‐Meraz, Rocío Arce‐González, Federico Graue‐Wiechers, Mario Gutiérrez‐Paz, Tatiana Urrea‐Victoria, Ulises de Dios Cuadras, Oscar F. Chacón‐Camacho

Mol Genet Genomic Med. 2020 Jan; 8(1): 10.1002/mgg3.1044. Published online 2019 Nov 17. doi: 10.1002/mgg3.1044

PMCID:: PMC6978239

Abstract Article PDF–1.3M

Select item 69777517.

Computational analysis of functional single nucleotide polymorphisms associated with SLC26A4 gene

Mirza Jawad Ul Hasnain, Muhammad Shoaib, Salman Qadri, Bakhtawar Afzal, Tehreem Anwar, Syed Hassan Abbas, Amina Sarwar, Hafiz Muhammad Talha Malik, Muhammad Tariq Pervez

PLoS One. 2020; 15(1): e0225368. Published online 2020 Jan 23. doi: 10.1371/journal.pone.0225368

PMCID:: PMC6977751

Abstract Article PDF–2.4M

Select item 69731158.

Variation in nomenclature of somatic variants for selection of oncological therapies: Can we reach a consensus soon?

Cleo Keppens, Véronique Tack, Kelly Dufraing, Etienne Rouleau, Marjolijn J. L. Ligtenberg, Ed Schuuring, Elisabeth M. C. Dequeker

Hum Mutat. 2020 Jan; 41(1): 7–16. Published online 2019 Oct 14. doi: 10.1002/humu.23926

PMCID:: PMC6973115

Abstract Article PDF–848K

Select item 69667099.

SEL1L plays a major role in human malignant gliomas

Marta Mellai, Laura Annovazzi, Renzo Boldorini, Luca Bertero, Paola Cassoni, Pasquale De Blasio, Ida Biunno, Davide Schiffer

J Pathol Clin Res. 2020 Jan; 6(1): 17–29. Published online 2019 Sep 30. doi: 10.1002/cjp2.134

PMCID:: PMC6966709

Abstract Article PDF–4.8M

Select item 696652910.

Standardization of Somatic Variant Classifications in Solid and Haematological Tumours by a Two-Level Approach of Biological and Clinical Classes: An Initiative of the Belgian ComPerMed Expert Panel

Guy Froyen, Marie Le Mercier, Els Lierman, Karl Vandepoele, Friedel Nollet, Elke Boone, Joni Van der Meulen, Koen Jacobs, Suzan Lambin, Sara Vander Borght, Els Van Valckenborgh, Aline Antoniou, Aline Hébrant

Cancers (Basel) 2019 Dec; 11(12): 2030. Published online 2019 Dec 16. doi: 10.3390/cancers11122030

PMCID:: PMC6966529

Abstract Article PDF–710K

Select item 696624011.

Blood-Brain Barrier and Delivery of Protein and Gene Therapeutics to Brain

William M. Pardridge

Front Aging Neurosci. 2019; 11: 373. Published online 2020 Jan 10. doi: 10.3389/fnagi.2019.00373

PMCID:: PMC6966240

Abstract Article PDF–4.2M

Select item 696289112.

Serum EGFR gene mutation status via second-generation sequencing and clinical features of patients with advanced lung cancer

Zhen Zhang, Shengyu Zhou

Int J Clin Exp Pathol. 2018; 11(7): 3551–3558. Published online 2018 Jul 1.

PMCID:: PMC6962891

Abstract Article PDF–731K

Select item 695682113.

The combination of bevacizumab/Avastin and erlotinib/Tarceva is relevant for the treatment of metastatic renal cell carcinoma: the role of a synonymous mutation of the EGFR receptor

Renaud Grépin, Mélanie Guyot, Aurore Dumond, Jérôme Durivault, Damien Ambrosetti, Jean-François Roussel, Florence Dupré, Hervé Quintens, Gilles Pagès

Theranostics. 2020; 10(3): 1107–1121. Published online 2020 Jan 1. doi: 10.7150/thno.38346

PMCID:: PMC6956821

Abstract Article PDF–2.5M

Select item 694335414.

Compensatory upregulation of aldo-keto reductase 1B10 to protect hepatocytes against oxidative stress during hepatocarcinogenesis

Yongzhen Liu, Jing Zhang, Hui Liu, Guiwen Guan, Ting Zhang, Leijie Wang, Xuewei Qi, Huiling Zheng, Chia-Chen Chen, Jia Liu, Deliang Cao, Fengmin Lu, Xiangmei Chen

Am J Cancer Res. 2019; 9(12): 2730–2748. Published online 2019 Dec 1.

PMCID:: PMC6943354

Abstract Article PDF–6.9M

Select item 692777315.

Inter-laboratory proficiency testing scheme for tumour next-generation sequencing in Ontario: a pilot study

T. Spence, N. Stickle, C. Yu, H. Chow, H. Feilotter, B. Lo, E. McCready, B. Sadikovic, L.L. Siu, P.L. Bedard, T.L. Stockley

Curr Oncol. 2019 Dec; 26(6): e717–e732. Published online 2019 Dec 1. doi: 10.3747/co.26.5379

PMCID:: PMC6927773

Abstract Article PDF–823K

Select item 690018216.

Long non‐coding RNAs influence the transcriptome in pulmonary arterial hypertension: the role of PAXIP1‐AS1

Katharina Jandl, Helene Thekkekara Puthenparampil, Leigh M Marsh, Julia Hoffmann, Jochen Wilhelm, Christine Veith, Katharina Sinn, Walter Klepetko, Horst Olschewski, Andrea Olschewski, Matthias Brock, Grazyna Kwapiszewska

J Pathol. 2019 Mar; 247(3): 357–370. Published online 2019 Jan 16. doi: 10.1002/path.5195

PMCID:: PMC6900182

Abstract Article PDF–4.5M

Select item 688612617.

Targeting PKCδ as a Therapeutic Strategy against Heterogeneous Mechanisms of EGFR Inhibitor Resistance in EGFR-Mutant Lung Cancer

Pei-Chih Lee, Yueh-Fu Fang, Hirohito Yamaguchi, Wei-Jan Wang, Tse-Ching Chen, Xuan Hong, Baozhen Ke, Weiya Xia, Yongkun Wei, Zhengyu Zha, Yan Wang, Han-Pin Kuo, Chih-Wei Wang, Chih-Yen Tu, Chia-Hung Chen, Wei-Chien Huang, Shu-Fen Chiang, Lei Nie, Junwei Hou, Chun-Te Chen, Longfei Huo, Wen-Hao Yang, Rong Deng, Katsuya Nakai, Yi-Hsin Hsu, Shih-Shin Chang, Tai-Jan Chiu, Jun Tang, Ran Zhang, Li Wang, Bingliang Fang, Ting Chen, Kwok-Kin Wong, Jennifer L. Hsu, Mien-Chie Hung

Cancer Cell. Author manuscript; available in PMC 2019 Dec 10.

Published in final edited form as: Cancer Cell. 2018 Dec 10; 34(6): 954–969.e4. doi: 10.1016/j.ccell.2018.11.007

PMCID:: PMC6886126

Abstract Article PDF–2.2M

Select item 688362718.

Validation of an epigenetic field of susceptibility to detect significant prostate cancer from non-tumor biopsies

Bing Yang, Tyler Etheridge, Johnathon McCormick, Adam Schultz, Tariq A. Khemees, Nathan Damaschke, Glen Leverson, Kaitlin Woo, Geoffrey A. Sonn, Eric A. Klein, Mike Fumo, Wei Huang, David F. Jarrard

Clin Epigenetics. 2019; 11: 168. Published online 2019 Nov 28. doi: 10.1186/s13148-019-0771-5

PMCID:: PMC6883627

Abstract Article PDF–807K

Select item 688190519.

Rapid and ultrasensitive digital PCR (dPCR) profiling of EGFRvIII in tumor cells and tissues

Deeksha Saxena, Saad Sheikh, Gary Kao, Zev A Binder, Michelle Alonso-Basanta, Donald M O’Rourke, MacLean P Nasrallah, Jay F Dorsey

Neurooncol Adv. 2019 May-Dec; 1(1): vdz030. Published online 2019 Nov 28. doi: 10.1093/noajnl/vdz030

PMCID:: PMC6881905

Abstract Article PDF–1.5M

Select item 684249720.

A novel missense in GLI3 possibly affecting one of the zinc finger domains may lead to postaxial synpolydactyly: case report

Qianqian Zou, Zhigang Tian, Jie Zheng, Xiufang Zhi, Xiaojie Du, Jianbo Shu, Chunquan Cai

BMC Med Genet. 2019; 20: 174. Published online 2019 Nov 9. doi: 10.1186/s12881-019-0889-5

PMCID:: PMC6842497

Abstract Article PDF–1.0M

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