PMC Links for GEO Profiles (Select 100687591) - PMC

Toshiaki Miyazaki, Suyoun Chung, Hiroaki Sakai, Hirokazu Ohata, Yuuki Obata, Daisuke Shiokawa, Yukihiro Mizoguchi, Takashi Kubo, Hitoshi Ichikawa, Hirokazu Taniguchi, Kazunori Aoki, Tomoyoshi Soga, Hitoshi Nakagama, Koji Okamoto

Cancer Sci. 2022 Jan; 113(1): 170–181. Published online 2021 Dec 2. doi: 10.1111/cas.15182

PMCID:: PMC8748246

Abstract Article PDF–3.5M

Select item 87145535.

TDO2 overexpression correlates with poor prognosis, cancer stemness, and resistance to cetuximab in bladder cancer

Quoc Thang Pham, Daiki Taniyama, Shintaro Akabane, Kenji Harada, Takashi Babasaki, Yohei Sekino, Tetsuraro Hayashi, Naoya Sakamoto, Kazuhiro Sentani, Naohide Oue, Wataru Yasui

Cancer Rep (Hoboken) 2021 Dec; 4(6): e1417. Published online 2021 Jun 7. doi: 10.1002/cnr2.1417

PMCID:: PMC8714553

Abstract Article PDF–4.9M

Select item 87002006.

Immuno-Metabolic Modulation of Liver Oncogenesis by the Tryptophan Metabolism

Véronique Trézéguet, Hala Fatrouni, Aksam J. Merched

Cells. 2021 Dec; 10(12): 3469. Published online 2021 Dec 9. doi: 10.3390/cells10123469

PMCID:: PMC8700200

Abstract Article PDF–2.7M

Select item 85507597.

RNF43 inhibits WNT5A-driven signaling and suppresses melanoma invasion and resistance to the targeted therapy

Tomasz Radaszkiewicz, Michaela Nosková, Kristína Gömöryová, Olga Vondálová Blanářová, Katarzyna Anna Radaszkiewicz, Markéta Picková, Ráchel Víchová, Tomáš Gybeľ, Karol Kaiser, Lucia Demková, Lucia Kučerová, Tomáš Bárta, David Potěšil, Zbyněk Zdráhal, Karel Souček, Vítězslav Bryja

eLife. 2021; 10: e65759. Published online 2021 Oct 27. doi: 10.7554/eLife.65759

PMCID:: PMC8550759

Abstract Article PDF–7.4M

Select item 83789718.

TDO2 Was Downregulated in Hepatocellular Carcinoma and Inhibited Cell Proliferation by Upregulating the Expression of p21 and p27

Chengpeng Yu, Dean Rao, He Zhu, Qiumeng Liu, Wenjie Huang, Long Zhang, Huifang Liang, Jia Song, Zeyang Ding

Biomed Res Int. 2021; 2021: 4708439. Published online 2021 Aug 13. doi: 10.1155/2021/4708439

PMCID:: PMC8378971

Abstract Article PDF–2.2M

Select item 81650309.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 806079310.

Tryptophan 2, 3-dioxygenase promotes proliferation, migration and invasion of ovarian cancer cells

Yuemei Zhao, Fengxing Tao, Jiayu Jiang, Lina Chen, Jizao Du, Xiaoxiao Cheng, Qin He, Shouhui Zhong, Wei Chen, Xiaoli Wu, Rongying Ou, Yunsheng Xu, Kai-Fu Tang

Mol Med Rep. 2021 Jun; 23(6): 445. Published online 2021 Apr 12. doi: 10.3892/mmr.2021.12084

PMCID:: PMC8060793

Abstract Article PDF–2.0M

Select item 767932711.

Different effects of tryptophan 2,3-dioxygenase inhibition on SK-Mel-28 and HCT-8 cancer cell lines

Sara Paccosi, Marta Cecchi, Angela Silvano, Sergio Fabbri, Astrid Parenti

J Cancer Res Clin Oncol. 2020; 146(12): 3155–3163. Published online 2020 Aug 10. doi: 10.1007/s00432-020-03351-2

PMCID:: PMC7679327

Abstract Article PDF–1.1M

Select item 716998312.

A reference map of the human binary protein interactome

Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood

Nature. Author manuscript; available in PMC 2020 Oct 8.

Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x

PMCID:: PMC7169983

Abstract Article PDF–5.4M

Select item 703311413.

Both IDO1 and TDO contribute to the malignancy of gliomas via the Kyn–AhR–AQP4 signaling pathway

Lisha Du, Zikang Xing, Bangbao Tao, Tianqi Li, Dan Yang, Weirui Li, Yuanting Zheng, Chunxiang Kuang, Qing Yang

Signal Transduct Target Ther. 2020; 5: 10. Published online 2020 Feb 21. doi: 10.1038/s41392-019-0103-4

Correction in:: Signal Transduct Target Ther. 2021; 6: 385.

PMCID:: PMC7033114

Abstract Article PDF–5.1M

Select item 690540814.

Hypoxia Inducible Factor 1α Inhibits the Expression of Immunosuppressive Tryptophan-2,3-Dioxygenase in Glioblastoma

Soumya R. Mohapatra, Ahmed Sadik, Lars-Oliver Tykocinski, Jørn Dietze, Gernot Poschet, Ines Heiland, Christiane A. Opitz

Front Immunol. 2019; 10: 2762. Published online 2019 Dec 4. doi: 10.3389/fimmu.2019.02762

PMCID:: PMC6905408

Abstract Article PDF–994K

Select item 674264615.

Extensive disruption of protein interactions by genetic variants across the allele frequency spectrum in human populations

Robert Fragoza, Jishnu Das, Shayne D. Wierbowski, Jin Liang, Tina N. Tran, Siqi Liang, Juan F. Beltran, Christen A. Rivera-Erick, Kaixiong Ye, Ting-Yi Wang, Li Yao, Matthew Mort, Peter D. Stenson, David N. Cooper, Xiaomu Wei, Alon Keinan, John C. Schimenti, Andrew G. Clark, Haiyuan Yu

Nat Commun. 2019; 10: 4141. Published online 2019 Sep 12. doi: 10.1038/s41467-019-11959-3

PMCID:: PMC6742646

Abstract Article PDF–1.2M

Select item 553161116.

Architecture of the human interactome defines protein communities and disease networks

Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper

Nature. Author manuscript; available in PMC 2017 Nov 17.

Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366

PMCID:: PMC5531611

Abstract Article PDF–2.7M

Select item 542135617.

Hypertryptophanemia due to tryptophan 2,3-dioxygenase deficiency

Patrick Ferreira, Inchul Shin, Iveta Sosova, Kednerlin Dornevil, Shailly Jain, Deborah Dewey, Fange Liu, Aimin Liu

Mol Genet Metab. Author manuscript; available in PMC 2018 Apr 1.

Published in final edited form as: Mol Genet Metab. 2017 Apr; 120(4): 317–324. Published online 2017 Mar 1. doi: 10.1016/j.ymgme.2017.02.009

PMCID:: PMC5421356

Abstract Article PDF–1.1M

Select item 507183218.

Molecular basis for catalysis and substrate-mediated cellular stabilization of human tryptophan 2,3-dioxygenase

Ariel Lewis-Ballester, Farhad Forouhar, Sung-Mi Kim, Scott Lew, YongQiang Wang, Shay Karkashon, Jayaraman Seetharaman, Dipanwita Batabyal, Bing-Yu Chiang, Munif Hussain, Maria Almira Correia, Syun-Ru Yeh, Liang Tong

Sci Rep. 2016; 6: 35169. Published online 2016 Oct 20. doi: 10.1038/srep35169

PMCID:: PMC5071832

Abstract Article PDF–2.5M

Select item 499278519.

Expression Pattern and Clinicopathological Relevance of the Indoleamine 2,3-Dioxygenase 1/Tryptophan 2,3-Dioxygenase Protein in Colorectal Cancer

I-Chien Chen, Kuen-Haur Lee, Ying-Hua Hsu, Wei-Ran Wang, Chuan-Mu Chen, Ya-Wen Cheng

Dis Markers. 2016; 2016: 8169724. Published online 2016 Aug 8. doi: 10.1155/2016/8169724

PMCID:: PMC4992785

Abstract Article PDF–1.1M

Select item 498558320.

Negative Impact of Hypoxia on Tryptophan 2,3-Dioxygenase Function

Frank Elbers, Claudia Woite, Valentina Antoni, Sara Stein, Hiroshi Funakoshi, Toshikazu Nakamura, Gereon Schares, Walter Däubener, Silvia K. Eller

Mediators Inflamm. 2016; 2016: 1638916. Published online 2016 Aug 2. doi: 10.1155/2016/1638916

PMCID:: PMC4985583

Abstract Article PDF–1.3M

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