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Select item 102757591.

Targeting MFAP5 in cancer-associated fibroblasts sensitizes pancreatic cancer to PD-L1-based immunochemotherapy via remodeling the matrix

Yi Duan, Xiaozhen Zhang, Honggang Ying, Jian Xu, Hanshen Yang, Kang Sun, Lihong He, Muchun Li, Yongtao Ji, Tingbo Liang, Xueli Bai

Oncogene. 2023; 42(25): 2061–2073. Published online 2023 May 8. doi: 10.1038/s41388-023-02711-9

PMCID:: PMC10275759

Abstract Article PDF–15M

Select item 81917422.

Comprehensive proteomic characterization of stem cell-derived extracellular matrices

Héloïse Ragelle, Alexandra Naba, Benjamin L. Larson, Fangheng Zhou, Miralem Prijic, Charles A. Whittaker, Amanda Del Rosario, Robert Langer, Richard O. Hynes, Daniel G. Anderson

Biomaterials. Author manuscript; available in PMC 2021 Jun 10.

Published in final edited form as: Biomaterials. 2017 Jun; 128: 147–159. Published online 2017 Mar 7. doi: 10.1016/j.biomaterials.2017.03.008

PMCID:: PMC8191742

Abstract Article PDF–1.5M

Select item 81650303.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 80787284.

Characterization of the Extracellular Matrix of Normal and Diseased Tissues Using Proteomics

Alexandra Naba, Oliver M. T. Pearce, Amanda Del Rosario, Duanduan Ma, Huiming Ding, Vinothini Rajeeve, Pedro R. Cutillas, Frances R. Balkwill, Richard O. Hynes

J Proteome Res. Author manuscript; available in PMC 2021 Apr 27.

Published in final edited form as: J Proteome Res. 2017 Aug 4; 16(8): 3083–3091. Published online 2017 Jul 19. doi: 10.1021/acs.jproteome.7b00191

PMCID:: PMC8078728

Abstract Article PDF–2.1M

Select item 68821855.

MFAP5 facilitates the aggressiveness of intrahepatic Cholangiocarcinoma by activating the Notch1 signaling pathway

Jian-Hui Li, Xiao-Xu Zhu, Fu-Xi Li, Chen-Song Huang, Xi-Tai Huang, Jie-Qin Wang, Zhuo-Xing Gao, Shi-Jin Li, Qiong-Cong Xu, Wei Zhao, Xiao-Yu Yin

J Exp Clin Cancer Res. 2019; 38: 476. Published online 2019 Nov 27. doi: 10.1186/s13046-019-1477-4

PMCID:: PMC6882185

Abstract Article PDF–4.0M

Select item 68255396.

Anticancer immunotherapy by MFAP5 blockade inhibits fibrosis and enhances chemosensitivity in ovarian and pancreatic cancer

Tsz-Lun Yeung, Cecilia S. Leung, Kay-Pong Yip, Jianting Sheng, Long Vien, Laura C. Bover, Michael J. Birrer, Stephen T.C. Wong, Samuel C. Mok

Clin Cancer Res. Author manuscript; available in PMC 2020 May 1.

Published in final edited form as: Clin Cancer Res. 2019 Nov 1; 25(21): 6417–6428. Published online 2019 Jul 22. doi: 10.1158/1078-0432.CCR-19-0187

PMCID:: PMC6825539

Abstract Article PDF–2.1M

Select item 67027717.

MAGP2, a Component of Extracellular Matrix, Is Upregulated in Colorectal Cancer and Negatively Modulated by miR-200b-3p

Wei Feifei, Guo Hui, Zhao Ruiqiang, Jiang Qunxiang, Xie Yu’an

Technol Cancer Res Treat. 2019; 18: 1533033819870777. Published online 2019 Aug 19. doi: 10.1177/1533033819870777

PMCID:: PMC6702771

Abstract Article PDF–881K

Select item 61287868.

Microfibril-associated glycoproteins MAGP-1 and MAGP-2 in Disease

Clarissa S. Craft, Thomas J. Broekelmann, Robert P. Mecham

Matrix Biol. Author manuscript; available in PMC 2019 Oct 1.

Published in final edited form as: Matrix Biol. 2018 Oct; 71-72: 100–111. Published online 2018 Mar 7. doi: 10.1016/j.matbio.2018.03.006

PMCID:: PMC6128786

Abstract Article PDF–955K

Select item 53568219.

MFAP5 and TNNC1: Potential markers for predicting occult cervical lymphatic metastasis and prognosis in early stage tongue cancer

Xi Yang, Kailiu Wu, Siyi Li, Longwei Hu, Jing Han, Dongwang Zhu, Xuerui Tian, Wei Liu, Zhen Tian, Laiping Zhong, Ming Yan, Chenping Zhang, Zhiyuan Zhang

Oncotarget. 2017 Jan 10; 8(2): 2525–2535. Published online 2016 Oct 4. doi: 10.18632/oncotarget.12446

PMCID:: PMC5356821

Abstract Article PDF–4.3M

Select item 512507210.

Clinically Relevant Variants Identified in Thoracic Aortic Aneurysm Patients by Research Exome Sequencing

Jeffrey A. Schubert, Benjamin J. Landis, Amy R. Shikany, Robert B. Hinton, Stephanie M. Ware

Am J Med Genet A. Author manuscript; available in PMC 2016 Nov 28.

Published in final edited form as: Am J Med Genet A. 2016 May; 170A(5): 1288–1294. Published online 2016 Feb 7. doi: 10.1002/ajmg.a.37568

PMCID:: PMC5125072

Abstract Article PDF–553K

Select item 487287911.

Extracellular matrix remodelling in response to venous hypertension: proteomics of human varicose veins

Javier Barallobre-Barreiro, Rahmi Oklu, Marc Lynch, Marika Fava, Ferheen Baig, Xiaoke Yin, Temo Barwari, David N. Potier, Hassan Albadawi, Marjan Jahangiri, Karen E. Porter, Michael T. Watkins, Sanjay Misra, Julianne Stoughton, Manuel Mayr

Cardiovasc Res. 2016 Jun 1; 110(3): 419–430. Published online 2016 Apr 11. doi: 10.1093/cvr/cvw075

PMCID:: PMC4872879

Abstract Article PDF–1.1M

Select item 481734512.

MAGP2 controls Notch via interactions with RGD binding integrins: Identification of a Novel ECM – Integrin – Notch Signaling Axis

Peter Deford, Kasey Brown, Rae Lee Richards, Aric King, Kristin Newburn, Katherine Westover, Allan R. Albig

Exp Cell Res. Author manuscript; available in PMC 2017 Feb 1.

Published in final edited form as: Exp Cell Res. 2016 Feb 1; 341(1): 84–91. Published online 2016 Jan 22. doi: 10.1016/j.yexcr.2016.01.011

PMCID:: PMC4817345

Abstract Article PDF–857K

Select item 425997813.

MFAP5 Loss-of-Function Mutations Underscore the Involvement of Matrix Alteration in the Pathogenesis of Familial Thoracic Aortic Aneurysms and Dissections

Mathieu Barbier, Marie-Sylvie Gross, Mélodie Aubart, Nadine Hanna, Ketty Kessler, Dong-Chuan Guo, Laurent Tosolini, Benoit Ho-Tin-Noe, Ellen Regalado, Mathilde Varret, Marianne Abifadel, Olivier Milleron, Sylvie Odent, Sophie Dupuis-Girod, Laurence Faivre, Thomas Edouard, Yves Dulac, Tiffany Busa, Laurent Gouya, Dianna M. Milewicz, Guillaume Jondeau, Catherine Boileau

Am J Hum Genet. 2014 Dec 4; 95(6): 736–743. doi: 10.1016/j.ajhg.2014.10.018

PMCID:: PMC4259978

Abstract Article PDF–1.1M

Select item 422362714.

Extracellular matrix signatures of human primary metastatic colon cancers and their metastases to liver

Alexandra Naba, Karl R Clauser, Charles A Whittaker, Steven A Carr, Kenneth K Tanabe, Richard O Hynes

BMC Cancer. 2014; 14: 518. Published online 2014 Jul 18. doi: 10.1186/1471-2407-14-518

PMCID:: PMC4223627

Abstract Article PDF–1.5M

Select item 418540715.

Calcium Dependent FAK/CREB/TNNC1 Signaling Mediates the Effect of Stromal MFAP5 on Ovarian Cancer Metastatic Potential

Cecilia S. Leung, Tsz-Lun Yeung, Kay-Pong Yip, Sunila Pradeep, Lavanya Balasubramanian, Jinsong Liu, Kwong-Kwok Wong, Lingegowda S. Mangala, Guillermo N. Armaiz-Pena, Gabriel Lopez-Berestein, Anil K. Sood, Michael J. Birrer, Samuel C. Mok

Nat Commun. Author manuscript; available in PMC 2015 Apr 3.

Published in final edited form as: Nat Commun. 2014; 5: 5092. Published online 2014 Oct 3. doi: 10.1038/ncomms6092

PMCID:: PMC4185407

Abstract Article PDF–3.2M

Select item 415176416.

Distinct isoform of FABP7 revealed by screening for retroelement-activated genes in diffuse large B-cell lymphoma

Frances E. Lock, Rita Rebollo, Katharine Miceli-Royer, Liane Gagnier, Sabrina Kuah, Artem Babaian, Maialen Sistiaga-Poveda, C. Benjamin Lai, Oksana Nemirovsky, Isabel Serrano, Christian Steidl, Mohammad M. Karimi, Dixie L. Mager

Proc Natl Acad Sci U S A. 2014 Aug 26; 111(34): E3534–E3543. Published online 2014 Aug 11. doi: 10.1073/pnas.1405507111

Correction in:: Proc Natl Acad Sci U S A. 2015 Aug 18; 112(33): E4630.

PMCID:: PMC4151764

Abstract Article PDF–2.0M

Select item 401708917.

Enriched Protein Screening of Human Bone Marrow Mesenchymal Stromal Cell Secretions Reveals MFAP5 and PENK as Novel IL-10 Modulators

Jack M Milwid, Jessica S Elman, Matthew Li, Keyue Shen, Arjun Manrai, Aaron Gabow, Joshua Yarmush, Yunxin Jiao, Anne Fletcher, Jungwoo Lee, Michael J Cima, Martin L Yarmush, Biju Parekkadan

Mol Ther. 2014 May; 22(5): 999–1007. Prepublished online 2014 Feb 5. Published online 2014 Mar 18. doi: 10.1038/mt.2014.17

PMCID:: PMC4017089

Abstract Article PDF–748K

Select item 378998218.

Microfibril-associated Glycoprotein 2 (MAGP2) Loss of Function Has Pleiotropic Effects in Vivo

Michelle D. Combs, Russell H. Knutsen, Thomas J. Broekelmann, Holly M. Toennies, Thomas J. Brett, Chantel A. Miller, Daniel L. Kober, Clarissa S. Craft, Jeffrey J. Atkinson, J. Michael Shipley, Barbara C. Trask, Robert P. Mecham

J Biol Chem. 2013 Oct 4; 288(40): 28869–28880. Published online 2013 Aug 20. doi: 10.1074/jbc.M113.497727