PMC Links for GEO Profiles (Select 100701966) - PMC

Select item 104958921.

G Protein-Coupled Receptor 75 (GPR75) As a Novel Molecule for Targeted Therapy of Cancer and Metabolic Syndrome

Mohammad-Reza Dashti, Fatemeh Ghorbanzadeh, Davoud Jafari-Gharabaghlou, Mahdi Farhoudi-Sefidan-Jadid, Nosratollah Zarghami

Asian Pac J Cancer Prev. 2023; 24(5): 1817–1825. doi: 10.31557/APJCP.2023.24.5.1817

PMCID:: PMC10495892

Abstract Article PDF–579K

Select item 102753962.

Sequencing of 640,000 exomes identifies GPR75 variants associated with protection from obesity

Parsa Akbari, Ankit Gilani, Olukayode Sosina, Jack A. Kosmicki, Lori Khrimian, Yi-Ya Fang, Trikaldarshi Persaud, Victor Garcia, Dylan Sun, Alexander Li, Joelle Mbatchou, Adam E. Locke, Christian Benner, Niek Verweij, Nan Lin, Sakib Hossain, Kevin Agostinucci, Jonathan V. Pascale, Ercument Dirice, Michael Dunn, Regeneron Genetics Center, DiscovEHR Collaboration, William E. Kraus, Svati H. Shah, Yii-Der I. Chen, Jerome I. Rotter, Daniel J. Rader, Olle Melander, Christopher D. Still, Tooraj Mirshahi, David J. Carey, Jaime Berumen-Campos, Pablo Kuri-Morales, Jesus Alegre-Díaz, Jason M. Torres, Jonathan R. Emberson, Rory Collins, Suganthi Balasubramanian, Alicia Hawes, Marcus Jones, Brian Zambrowicz, Andrew J. Murphy, Charles Paulding, Giovanni Coppola, John D. Overton, Jeffrey G. Reid, Alan R. Shuldiner, Michael Cantor, Hyun M. Kang, Goncalo R. Abecasis, Katia Karalis, Aris N. Economides, Jonathan Marchini, George D. Yancopoulos, Mark W. Sleeman, Judith Altarejos, Giusy Della Gatta, Roberto Tapia-Conyer, Michal L. Schwartzman, Aris Baras, Manuel A. R. Ferreira, Luca A. Lotta

Science. Author manuscript; available in PMC 2023 Jun 16.

Published in final edited form as: Science. 2021 Jul 2; 373(6550): eabf8683. doi: 10.1126/science.abf8683

PMCID:: PMC10275396

Abstract Article PDF–2.1M

Select item 101198903.

Uncovering the signalling, structure and function of the 20-HETE-GPR75 pairing: Identifying the chemokine CCL5 as a negative regulator of GPR75

Jonathan V. Pascale, Eon Joo Park, Adeniyi Michael Adebesin, John R. Falck, Michal Laniado Schwartzman, Victor Garcia

Br J Pharmacol. Author manuscript; available in PMC 2023 Apr 21.

Published in final edited form as: Br J Pharmacol. 2021 Sep; 178(18): 3813–3828. Published online 2021 Jun 15. doi: 10.1111/bph.15525

PMCID:: PMC10119890

Abstract Article PDF–2.1M

Select item 69577694.

GPR75 RECEPTOR MEDIATES 20-HETE-SIGNALING AND METASTATIC FEATURES OF ANDROGEN-INSENSITIVE PROSTATE CANCER CELLS

Sofia Cárdenas, Cecilia Colombero, Laura Panelo, Rambabu Dakarapu, Falck John R., Costas Monica A., Susana Nowicki

Biochim Biophys Acta Mol Cell Biol Lipids. Author manuscript; available in PMC 2021 Feb 1.

Published in final edited form as: Biochim Biophys Acta Mol Cell Biol Lipids. 2020 Feb; 1865(2): 158573. Published online 2019 Nov 21. doi: 10.1016/j.bbalip.2019.158573

PMCID:: PMC6957769

Abstract Article PDF–1.4M

Select item 61988075.

The Orphan G Protein-coupled Receptor 75 Signaling is Activated by the Chemokine CCL5

Dr. Simona Dedoni, Dr. Lee A. Campbell, Dr. Brandon K. Harvey, Dr. Valeria Avdoshina, Dr. Italo Mocchetti

J Neurochem. Author manuscript; available in PMC 2019 Sep 1.

Published in final edited form as: J Neurochem. 2018 Sep; 146(5): 526–539. Published online 2018 Aug 2. doi: 10.1111/jnc.14463

PMCID:: PMC6198807

Abstract Article PDF–1.9M

Select item 54462686.

20- HETE Signals Through G Protein-Coupled Receptor GPR75 (G_q) to Affect Vascular Function and Trigger Hypertension

Victor Garcia, Ankit Gilani, Brian Shkolnik, Varunkumar Pandey, Frank Fan Zhang, Rambabu Dakarapu, Shyam K. Gandham, N. Rami Reddy, Joan P. Graves, Artiom Gruzdev, Darryl C. Zeldin, Jorge H. Capdevila, John R. Falck, Michal Laniado Schwartzman

Circ Res. Author manuscript; available in PMC 2018 May 26.

Published in final edited form as: Circ Res. 2017 May 26; 120(11): 1776–1788. Published online 2017 Mar 21. doi: 10.1161/CIRCRESAHA.116.310525