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Items: 1 to 20 of 275

1.
Precision Dosing for Tacrolimus Using Genotypes and Clinical Factors in Kidney Transplant Recipients of European Ancestry
Mahmoud Al-Kofahi, William S. Oetting, David P. Schladt, Rory P. Remmel, Weihua Guan, Baolin Wu, Casey R. Dorr, Roslyn B. Mannon, Arthur J. Matas, Ajay K. Israni, Pamala A. Jacobson
J Clin Pharmacol. Author manuscript; available in PMC 2024 Jul 12.
Published in final edited form as: J Clin Pharmacol. 2021 Aug; 61(8): 1035–1044. Published online 2021 Feb 26. doi: 10.1002/jcph.1823
PMCID:
PMC11240873
AbstractArticlePDF–806K
2.
Association of genetic polymorphisms in SLCO1B3 and ABCC2 with docetaxel‐induced leukopenia
Kazuma Kiyotani, Taisei Mushiroda, Michiaki Kubo, Hitoshi Zembutsu, Yuichi Sugiyama, Yusuke Nakamura
Cancer Sci. 2008 May; 99(5): 967–972. Published online 2008 Feb 20. doi: 10.1111/j.1349-7006.2008.00765.x
PMCID:
PMC11159748
AbstractArticlePDF–101K
3.
Bone marrow niche chemoprotection of metastatic solid tumors mediated by CYP3A4
Gabriel Ghiaur, Kenneth C. Valkenburg, Christopher Esteb, Alexander Ambinder, Philip H. Imus, Kenneth J. Pienta, Richard J. Jones
Cancer. Author manuscript; available in PMC 2024 Mar 27.
Published in final edited form as: Cancer. 2023 Jun 1; 129(11): 1744–1751. Published online 2023 Feb 25. doi: 10.1002/cncr.34704
PMCID:
PMC10966383
AbstractArticlePDF–775K
4.
Functional maturation of cytochromes P450 3A4 and 2D6 relies on GAPDH- and Hsp90-Dependent heme allocation
Sidra Islam, Dhanya Thamaraparambil Jayaram, Pranjal Biswas, Dennis J. Stuehr
J Biol Chem. 2024 Feb; 300(2): 105633. Published online 2024 Jan 8. doi: 10.1016/j.jbc.2024.105633
PMCID:
PMC10840333
AbstractArticlePDF–2.2M
5.
Cyp3A4 *1G polymorphism is associated with alcohol drinking: A 5-year retrospective single centered population-based study in China
Xiaoqing Jia, Xiaoting Zhang, Tao Zhou, Dalong Sun, Rong Li, Na Yang, Zheng Luo
PLoS One. 2023; 18(12): e0295184. Published online 2023 Dec 20. doi: 10.1371/journal.pone.0295184
PMCID:
PMC10732449
AbstractArticlePDF–1.1M
6.
Down-Regulation of CYP3A4 by the KCa1.1 Inhibition Is Responsible for Overcoming Resistance to Doxorubicin in Cancer Spheroid Models
Susumu Ohya, Junko Kajikuri, Hiroaki Kito, Miki Matsui
Int J Mol Sci. 2023 Nov; 24(21): 15672. Published online 2023 Oct 27. doi: 10.3390/ijms242115672
PMCID:
PMC10648085
AbstractArticlePDF–5.7M
7.
The roles of CYP2C19 and CYP3A4 in the in vitro metabolism of β‐eudesmol in human liver: Reaction phenotyping and enzyme kinetics
Nadda Muhamad, Kesara Na‐Bangchang
Pharmacol Res Perspect. 2023 Dec; 11(6): e01149. Published online 2023 Oct 30. doi: 10.1002/prp2.1149
PMCID:
PMC10614204
AbstractArticlePDF–1.3M
8.
Effects of CYP3A4 and CYP2C9 genotype on systemic anastrozole and fulvestrant concentrations in SWOG S0226
Delaney V Rutherford, Sarah Medley, Nicholas C Henderson, Christina L Gersch, Ted A Vandenberg, Kathy S Albain, Shaker R Dakhil, Nagendra R Tirumali, Julie R Gralow, Gabriel N Hortobagyi, Lajos Pusztai, Rita S Mehta, Daniel F Hayes, Kelley M Kidwell, N Lynn Henry, William E Barlow, James M Rae, Daniel L Hertz
Pharmacogenomics. 2023 Aug; 24(12): 665–673. Published online 2023 Aug 23. doi: 10.2217/pgs-2023-0097
PMCID:
PMC10565537
AbstractArticlePDF–784K
9.
Association between CYP3A4/CYP3A5 genetic polymorphisms and treatment outcomes of atorvastatin worldwide: is there enough research on the Egyptian population?
Mohammed G. Maslub, Mahasen A. Radwan, Nur Aizati Athirah Daud, Abubakar Sha’aban
Eur J Med Res. 2023; 28: 381. Published online 2023 Sep 27. doi: 10.1186/s40001-023-01038-1
PMCID:
PMC10523700
AbstractArticlePDF–1.4M
10.
Potential Association of Cytochrome P450 Copy Number Alteration in Tumour with Chemotherapy Resistance in Lung Adenocarcinoma Patients
Evelyn Incze, Katalin Mangó, Ferenc Fekete, Ádám Ferenc Kiss, Ádám Póti, Tünde Harkó, Judit Moldvay, Dávid Szüts, Katalin Monostory
Int J Mol Sci. 2023 Sep; 24(17): 13380. Published online 2023 Aug 29. doi: 10.3390/ijms241713380
PMCID:
PMC10487787
AbstractArticlePDF–1.1M
11.
Interaction of CYP3A4 with caffeine: First insights into multiple substrate binding
Irina F. Sevrioukova
J Biol Chem. 2023 Sep; 299(9): 105117. Published online 2023 Jul 29. doi: 10.1016/j.jbc.2023.105117
PMCID:
PMC10470200
AbstractArticlePDF–2.3M
12.
The impact of ABCB1, CYP3A4/5 and ABCG2 gene polymorphisms on rivaroxaban trough concentrations and bleeding events in patients with non-valvular atrial fibrillation
Tingting Wu, Shuyi Wu, Li Li, Jing Xiang, Na Wang, Wenjun Chen, Jinhua Zhang
Hum Genomics. 2023; 17: 59. Published online 2023 Jul 7. doi: 10.1186/s40246-023-00506-3
PMCID:
PMC10327396
AbstractArticlePDF–729K
13.
The Influence of CYP3A4 Polymorphism in Sex Steroids as a Risk Factor for Breast Cancer
Melissa Gonzalez Veiga, Rogério Tadeu Felizi, Dayane Guerino Reis, Ivo Carelli Filho, Cesar Eduardo Fernandes, Ricardo Peres do Souto, Emerson Oliveira
Rev Bras Ginecol Obstet. 2018 Nov; 40(11): 699–704. Published online 2018 Oct 18. doi: 10.1055/s-0038-1673365
PMCID:
PMC10309480
AbstractArticlePDF–218K
14.
Evaluating the Impacts of CYP3A4*1B and CYP3A5*3 Variations on Pharmacokinetic Behavior and Clinical Outcomes in Multiple Myeloma Patients With Autologous Stem Cell Transplant
JUNAN LI, YU KYOUNG CHO, DOUGLAS W. SBOROV, MITCH A. PHELPS, CRAIG C. HOFMEISTER, MING J. POI
Cancer Genomics Proteomics. 2023 Jan-Feb; 20(1): 9–17. Published online 2023 Jan 3. doi: 10.21873/cgp.20360
PMCID:
PMC9806672
AbstractArticlePDF–400K
15.
Detoxification of Aflatoxin B1 Contaminated Maize Using Human CYP3A4
Marie Yamada, Koji Hatsuta, Mayuko Niikawa, Hiromasa Imaishi
J Microbiol Biotechnol. 2020 Aug 28; 30(8): 1207–1213. Published online 2020 May 13. doi: 10.4014/jmb.2003.03032
PMCID:
PMC9728267
AbstractArticlePDF–772K
16.
Regulatory variants in a novel distal enhancer regulate the expression of CYP3A4 and CYP3A5
Joseph M. Collins, Adaeze C. Nworu, Somayya J. Mohammad, Liang Li, Chengcheng Li, Chuanjiang Li, Ethan Schwendeman, Mattew Cefalu, Mahmoud Abdel‐Rasoul, Jessie W. Sun, Sakima A. Smith, Danxin Wang
Clin Transl Sci. 2022 Nov; 15(11): 2720–2731. Published online 2022 Sep 20. doi: 10.1111/cts.13398
PMCID:
PMC9652438
AbstractArticlePDF–1.0M
17.
Crystal Structure of CYP3A4 Complexed with Fluorol Identifies the Substrate Access Channel as a High-Affinity Ligand Binding Site
Irina F. Sevrioukova
Int J Mol Sci. 2022 Oct; 23(20): 12591. Published online 2022 Oct 20. doi: 10.3390/ijms232012591
PMCID:
PMC9604483
AbstractArticlePDF–3.2M
18.
Tacrolimus CYP3A Single-Nucleotide Polymorphisms and Preformed T- and B-Cell Alloimmune Memory Improve Current Pretransplant Rejection-Risk Stratification in Kidney Transplantation
Elena Crespo, Anna Vidal-Alabró, Thomas Jouve, Pere Fontova, Maik Stein, Sonila Mocka, Maria Meneghini, Anett Sefrin, Petra Hruba, Montserrat Gomà, Alba Torija, Laura Donadeu, Alex Favà, Josep M. Cruzado, Edoardo Melilli, Francesc Moreso, Ondrej Viklicky, Frederike Bemelman, Petra Reinke, Josep Grinyó, Nuria Lloberas, Oriol Bestard
Front Immunol. 2022; 13: 869554. Published online 2022 Jun 27. doi: 10.3389/fimmu.2022.869554
PMCID:
PMC9272702
AbstractArticlePDF–3.4M
19.
Efavirenz Induces CYP2B6-Mediated Hydroxylation of Bupropion in Healthy Subjects
Sarah M. Robertson, Frank Maldarelli, Ven Natarajan, Elizabeth Formentini, Raul M. Alfaro, Scott R. Penzak
J Acquir Immune Defic Syndr. Author manuscript; available in PMC 2022 Apr 25.
Published in final edited form as: J Acquir Immune Defic Syndr. 2008 Dec 15; 49(5): 513–519. doi: 10.1097/QAI.0b013e318183a425
PMCID:
PMC9036313
AbstractArticlePDF–472K
20.
Midazolam as a Probe for Drug–Drug Interactions Mediated by CYP3A4: Homotropic Allosteric Mechanism of Site-Specific Hydroxylation
Ilia G. Denisov, Yelena V. Grinkova, Tyler Camp, Mark A. McLean, Stephen G. Sligar
Biochemistry. Author manuscript; available in PMC 2022 Jun 1.
Published in final edited form as: Biochemistry. 2021 Jun 1; 60(21): 1670–1681. Published online 2021 May 20. doi: 10.1021/acs.biochem.1c00161
PMCID:
PMC8857940
AbstractArticlePDF–1.7M

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