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Select item 112908531.

Cholesterol-dependent dynamic changes in the conformation of the type 1 cholecystokinin receptor affect ligand binding and G protein coupling

Kaleeckal G. Harikumar, Peishen Zhao, Brian P. Cary, Xiaomeng Xu, Aditya J. Desai, Maoqing Dong, Jesse I. Mobbs, Chirine Toufaily, Sebastian G. B. Furness, Arthur Christopoulos, Matthew J. Belousoff, Denise Wootten, Patrick M. Sexton, Laurence J. Miller

PLoS Biol. 2024 Jul; 22(7): e3002673. Published online 2024 Jul 31. doi: 10.1371/journal.pbio.3002673

PMCID:: PMC11290853

Abstract Article PDF–3.4M

Select item 86047282.

Ligand recognition and G-protein coupling selectivity of cholecystokinin A receptor

Qiufeng Liu, Dehua Yang, Youwen Zhuang, Tristan I. Croll, Xiaoqing Cai, Antao Dai, Xinheng He, Jia Duan, Wanchao Yin, Chenyu Ye, Fulai Zhou, Beili Wu, Qiang Zhao, H. Eric Xu, Ming-Wei Wang, Yi Jiang

Nat Chem Biol. 2021; 17(12): 1238–1244. Published online 2021 Sep 23. doi: 10.1038/s41589-021-00841-3

PMCID:: PMC8604728

Abstract Article PDF–6.2M

Select item 82085693.

Structures of the human cholecystokinin 1 (CCK1) receptor bound to Gs and Gq mimetic proteins provide insight into mechanisms of G protein selectivity

Jesse I. Mobbs, Matthew J. Belousoff, Kaleeckal G. Harikumar, Sarah J. Piper, Xiaomeng Xu, Sebastian G. B. Furness, Hari Venugopal, Arthur Christopoulos, Radostin Danev, Denise Wootten, David M. Thal, Laurence J. Miller, Patrick M. Sexton

PLoS Biol. 2021 Jun; 19(6): e3001295. Published online 2021 Jun 4. doi: 10.1371/journal.pbio.3001295

Update in:: PLoS Biol. 2024 Jul; 22(7): e3002673.

PMCID:: PMC8208569

Abstract Article PDF–4.0M

Select item 76015274.

Photodynamic Activation of Cholecystokinin 1 Receptor with Different Genetically Encoded Protein Photosensitizers and from Varied Subcellular Sites

Yuan Li, Zong Jie Cui

Biomolecules. 2020 Oct; 10(10): 1423. Published online 2020 Oct 8. doi: 10.3390/biom10101423

PMCID:: PMC7601527

Abstract Article PDF–2.3M

Select item 67365455.

Chromosomal Localization of the Gastric and Brain Receptors for Cholecystokinin (CCKAR and CCKBR) in Human and Mouse

K. HUPPI, D. SIWARSKI, J. R. PISEGNA, S. WANK

Genomics. Author manuscript; available in PMC 2019 Sep 10.

Published in final edited form as: Genomics. 1995 Feb 10; 25(3): 727–729. doi: 10.1016/0888-7543(95)80018-h

PMCID:: PMC6736545

Abstract Article PDF–841K

Select item 47279006.

Variants near CCK receptors are associated with electrophysiological responses to prepulse startle stimuli in a Mexican American cohort

Trina M. Norden-Krichmar, Ian R. Gizer, Evelyn Phillips, Kirk C. Wilhelmsen, Nicholas J. Schork, Cindy L. Ehlers

Twin Res Hum Genet. Author manuscript; available in PMC 2016 Dec 1.

Published in final edited form as: Twin Res Hum Genet. 2015 Dec; 18(6): 727–737. Published online 2015 Nov 26. doi: 10.1017/thg.2015.77

PMCID:: PMC4727900

Abstract Article PDF–912K

Select item 43983207.

Functional Synergy between Cholecystokinin Receptors CCKAR and CCKBR in Mammalian Brain Development

Sayoko Nishimura, Kaya Bilgüvar, Keiko Ishigame, Nenad Sestan, Murat Günel, Angeliki Louvi

PLoS One. 2015; 10(4): e0124295. Published online 2015 Apr 15. doi: 10.1371/journal.pone.0124295

PMCID:: PMC4398320

Abstract Article PDF–29M

Select item 43059548.

Gallbladder motor function, plasma cholecystokinin and cholecystokinin receptor of gallbladder in cholesterol stone patients

Jian Zhu, Tian-Quan Han, Sheng Chen, Yu Jiang, Sheng-Dao Zhang

World J Gastroenterol. 2005 Mar 21; 11(11): 1685–1689. Published online 2005 Mar 21. doi: 10.3748/wjg.v11.i11.1685

PMCID:: PMC4305954

Abstract Article PDF–335K

Select item 41402879.

A Type 1 Cholecystokinin Receptor Mutant That Mimics the Dysfunction Observed for Wild Type Receptor in a High Cholesterol Environment

Aditya J. Desai, Kaleeckal G. Harikumar, Laurence J. Miller

J Biol Chem. 2014 Jun 27; 289(26): 18314–18326. Published online 2014 May 13. doi: 10.1074/jbc.M114.570200

PMCID:: PMC4140287

Abstract Article PDF–2.2M

Select item 408286110.

Differential Expression of Cholecystokinin A Receptor in Gallbladder Cancer in the Young and Elderly Suggests Two Subsets of the Same Disease?

Hasan Raza Kazmi, Abhijit Chandra, Kavita Baghel, Anshuman Singh, Jaya Nigam, Devendra Parmar, Abbas Ali Mahdi, Sudhir K. Goel, Sandeep Kumar

Biomed Res Int. 2014; 2014: 625695. Published online 2014 Jun 15. doi: 10.1155/2014/625695

PMCID:: PMC4082861

Abstract Article PDF–749K

Select item 404734111.

Investigation of cholecystokinin receptors in the human lower esophageal sphincter

Jun-Feng Liu, Jian Zhang, Xin-Bo Liu, Paul A Drew

World J Gastroenterol. 2014 Jun 7; 20(21): 6554–6559. Published online 2014 Jun 7. doi: 10.3748/wjg.v20.i21.6554

PMCID:: PMC4047341

Abstract Article PDF–1.0M

Select item 382058212.

Variants in CCK and CCKAR genes to susceptibility to biliary tract cancers and stones: a population-based study in Shanghai, China

Hong-Li Xu, Ann W. Hsing, Emily Vogtmann, Lisa W. Chu, Jia-Rong Cheng, Jing Gao, Yu-Ting Tan, Bing-Sheng Wang, Ming-Chang Shen, Yu-Tang Gao

J Gastroenterol Hepatol. Author manuscript; available in PMC 2014 Sep 1.

Published in final edited form as: J Gastroenterol Hepatol. 2013 Sep; 28(9): 10.1111/jgh.12278. doi: 10.1111/jgh.12278

PMCID:: PMC3820582

Abstract Article PDF–56K

Select item 354492013.

Cholecystokinin A Receptor (CCKAR) Gene Variation Is Associated with Language Lateralization

Sebastian Ocklenburg, Larissa Arning, Wanda M. Gerding, Jörg T. Epplen, Onur Güntürkün, Christian Beste

PLoS One. 2013; 8(1): e53643. Published online 2013 Jan 14. doi: 10.1371/journal.pone.0053643

PMCID:: PMC3544920

Abstract Article PDF–153K

Select item 324347014.

Differential sensitivity of types 1 and 2 cholecystokinin receptors to membrane cholesterol

Ross M. Potter, Kaleeckal G. Harikumar, S.Vincent Wu, Laurence J. Miller

J Lipid Res. 2012 Jan; 53(1): 137–148. doi: 10.1194/jlr.M020065

PMCID:: PMC3243470

Abstract Article PDF–944K

Select item 317805915.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 297086516.

A Candidate Gene Study of Obstructive Sleep Apnea in European Americans and African Americans

Emma K. Larkin, Sanjay R. Patel, Robert J. Goodloe, Yali Li, Xiaofeng Zhu, Courtney Gray-McGuire, Mark D. Adams, Susan Redline

Am J Respir Crit Care Med. 2010 Oct 1; 182(7): 947–953. Published online 2010 Jun 10. doi: 10.1164/rccm.201002-0192OC

PMCID:: PMC2970865

Abstract Article PDF–404K

Select item 296315417.

Association Study of 182 Candidate Genes in Anorexia Nervosa

Andrea Poyastro Pinheiro, Cynthia M. Bulik, Laura M. Thornton, Patrick F. Sullivan, Tammy L. Root, Cinnamon S. Bloss, Wade H. Berrettini, Nicholas J. Schork, Walter H. Kaye, Andrew W. Bergen, Pierre Magistretti, Harry Brandt, Steve Crawford, Scott Crow, Manfred M. Fichter, David Goldman, Katherine A. Halmi, Craig Johnson, Allan S. Kaplan, Pamela K. Keel, Kelly L. Klump, Maria La Via, James E. Mitchell, Michael Strober, Alessandro Rotondo, Janet Treasure, D. Blake Woodside

Am J Med Genet B Neuropsychiatr Genet. Author manuscript; available in PMC 2010 Oct 25.

Published in final edited form as: Am J Med Genet B Neuropsychiatr Genet. 2010 Jul; 153B(5): 1070–1080. doi: 10.1002/ajmg.b.31082

PMCID:: PMC2963154

Abstract Article PDF–315K

Select item 295069418.

Effects of cholesterol on CCK-1 receptors and caveolin-3 proteins recycling in human gallbladder muscle

P. Cong, V. Pricolo, P. Biancani, J. Behar

Am J Physiol Gastrointest Liver Physiol. 2010 Sep; 299(3): G742–G750. Published online 2010 Jun 17. doi: 10.1152/ajpgi.00064.2010

PMCID:: PMC2950694

Abstract Article

Select item 294516819.

Variation at the NFATC2 Locus Increases the Risk of Thiazolidinedione-Induced Edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) Study

Swneke D. Bailey, Changchun Xie, Ron Do, Alexandre Montpetit, Rafael Diaz, Viswanathan Mohan, Bernard Keavney, Salim Yusuf, Hertzel C. Gerstein, James C. Engert, Sonia Anand, on behalf of the DREAM investigators

Diabetes Care. 2010 Oct; 33(10): 2250–2253. Published online 2010 Jul 13. doi: 10.2337/dc10-0452

PMCID:: PMC2945168

Abstract Article PDF–153K

Select item 292192020.

Physiogenomic analysis of statin-treated patients: domain-specific counter effects within the ACACB gene on low-density lipoprotein cholesterol?

Gualberto Ruaño, Paul D Thompson, John P Kane, Clive R Pullinger, Andreas Windemuth, Richard L Seip, Mohan Kocherla, Theodore R Holford, Alan HB Wu

Pharmacogenomics. Author manuscript; available in PMC 2011 May 1.

Published in final edited form as: Pharmacogenomics. 2010 Jul; 11(7): 959–971. doi: 10.2217/pgs.10.58

PMCID:: PMC2921920

Abstract Article PDF–1.4M

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