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Items: 1 to 20 of 27

1.
Diminished Immune Response and Elevated Abundance in Gut Microbe Dubosiella in Mouse Models of Chronic Colitis with GBP5 Deficiency
Yichen Li, Wenxia Wang, Yuxuan Liu, Senru Li, Jingyu Wang, Linlin Hou
Biomolecules. 2024 Jul; 14(7): 873. Published online 2024 Jul 20. doi: 10.3390/biom14070873
PMCID:
PMC11274912
AbstractArticlePDF–7.7M
2.
Profiling the colonic mucosal response to fecal microbiota transplantation identifies a role for GBP5 in colitis in humans and mice
Laurence D. W. Luu, Abhimanu Pandey, Sudarshan Paramsothy, Chinh Ngo, Natalia Castaño-Rodríguez, Cheng Liu, Michael A. Kamm, Thomas J. Borody, Si Ming Man, Nadeem O. Kaakoush
Nat Commun. 2024; 15: 2645. Published online 2024 Mar 26. doi: 10.1038/s41467-024-46983-5
PMCID:
PMC10965925
AbstractArticlePDF–4.5M
3.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
4.
Guanylate-binding protein-5 is involved in inflammasome activation by bacterial DNA but only the cooperation of multiple GBPs accounts for control of Brucella abortus infection
Fabio V. Marinho, Camila Brito, Ana Carolina V. S. C. de Araujo, Sergio C. Oliveira
Front Immunol. 2024; 15: 1341464. Published online 2024 Feb 8. doi: 10.3389/fimmu.2024.1341464
PMCID:
PMC10885698
AbstractArticlePDF–5.3M
5.
Pathogen-selective killing by guanylate-binding proteins as a molecular mechanism leading to inflammasome signaling
Shouya Feng, Daniel Enosi Tuipulotu, Abhimanu Pandey, Weidong Jing, Cheng Shen, Chinh Ngo, Melkamu B. Tessema, Fei-Ju Li, Daniel Fox, Anukriti Mathur, Anyang Zhao, Runli Wang, Klaus Pfeffer, Daniel Degrandi, Masahiro Yamamoto, Patrick C. Reading, Gaetan Burgio, Si Ming Man
Nat Commun. 2022; 13: 4395. Published online 2022 Jul 29. doi: 10.1038/s41467-022-32127-0
PMCID:
PMC9338265
AbstractArticlePDF–3.0M
6.
Interferon-γ primes macrophages for pathogen ligand-induced killing via a caspase-8 and mitochondrial cell death pathway
Daniel S. Simpson, Jiyi Pang, Ashley Weir, Isabella Y. Kong, Melanie Fritsch, Maryam Rashidi, James P. Cooney, Kathryn C. Davidson, Mary Speir, Tirta M. Djajawi, Sebastian Hughes, Liana Mackiewicz, Merle Dayton, Holly Anderton, Marcel Doerflinger, Yexuan Deng, Allan Shuai Huang, Stephanie A. Conos, Hazel Tye, Seong H. Chow, Arfatur Rahman, Raymond S. Norton, Thomas Naderer, Sandra E. Nicholson, Gaetan Burgio, Si Ming Man, Joanna R. Groom, Marco J. Herold, Edwin D. Hawkins, Kate E. Lawlor, Andreas Strasser, John Silke, Marc Pellegrini, Hamid Kashkar, Rebecca Feltham, James E. Vince
Immunity. 2022 Mar 8; 55(3): 423–441.e9. Published online 2022 Feb 8. doi: 10.1016/j.immuni.2022.01.003
PMCID:
PMC8822620
AbstractArticlePDF–6.5M
7.
Osteoclast fusion and bone loss are restricted by interferon inducible guanylate binding proteins
David E. Place, R. K. Subbarao Malireddi, Jieun Kim, Peter Vogel, Masahiro Yamamoto, Thirumala-Devi Kanneganti
Nat Commun. 2021; 12: 496. Published online 2021 Jan 21. doi: 10.1038/s41467-020-20807-8
PMCID:
PMC7820603
AbstractArticlePDF–5.2M
8.
Interferon inducible GBPs restrict Burkholderia thailandensis motility induced cell-cell fusion
David E. Place, Benoit Briard, Parimal Samir, Rajendra Karki, Anannya Bhattacharya, Clifford S. Guy, Jennifer L. Peters, Sharon Frase, Peter Vogel, Geoffrey Neale, Masahiro Yamamoto, Thirumala-Devi Kanneganti
PLoS Pathog. 2020 Mar; 16(3): e1008364. Published online 2020 Mar 9. doi: 10.1371/journal.ppat.1008364
PMCID:
PMC7082077
AbstractArticlePDF–6.9M
9.
Mouse screen reveals multiple new genes underlying mouse and human hearing loss
Neil J. Ingham, Selina A. Pearson, Valerie E. Vancollie, Victoria Rook, Morag A. Lewis, Jing Chen, Annalisa Buniello, Elisa Martelletti, Lorenzo Preite, Chi Chung Lam, Felix D. Weiss, Zӧe Powis, Pim Suwannarat, Christopher J. Lelliott, Sally J. Dawson, Jacqueline K. White, Karen P. Steel
PLoS Biol. 2019 Apr; 17(4): e3000194. Published online 2019 Apr 11. doi: 10.1371/journal.pbio.3000194
PMCID:
PMC6459510
AbstractArticlePDF–5.1M
10.
Guanylate-binding protein 5 licenses caspase-11 for Gasdermin-D mediated host resistance to Brucella abortus infection
Daiane M. Cerqueira, Marco Túlio R. Gomes, Alexandre L. N. Silva, Marcella Rungue, Natan R. G. Assis, Erika S. Guimarães, Suellen B. Morais, Petr Broz, Dario S. Zamboni, Sergio C. Oliveira
PLoS Pathog. 2018 Dec; 14(12): e1007519. Published online 2018 Dec 27. doi: 10.1371/journal.ppat.1007519
PMCID:
PMC6326519
AbstractArticlePDF–3.0M
11.
Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors
Hyeonwoo Kim, Christiane D. Wrann, Mark Jedrychowski, Sara Vidoni, Yukiko Kitase, Kenichi Nagano, Chenhe Zhou, Joshua Chou, Virginia-Jeni A. Parkman, Scott J. Novick, Timothy S. Strutzenberg, Bruce D. Pascal, Phuong T. Le, Daniel J. Brooks, Alexander M. Roche, Kaitlyn K. Gerber, Laura Mattheis, Wenjing Chen, Hua Tu, Mary L. Bouxsein, Patrick R. Griffin, Roland Baron, Clifford J. Rosen, Lynda F. Bonewald, Bruce M. Spiegelman
Cell. Author manuscript; available in PMC 2019 Dec 13.
Published in final edited form as: Cell. 2018 Dec 13; 175(7): 1756–1768.e17. doi: 10.1016/j.cell.2018.10.025
Correction in:
Cell. 2019 Jul 11; 178(2): 507–508.
PMCID:
PMC6298040
AbstractArticlePDF–1.2M
12.
NADPH Oxidase and Guanylate Binding Protein 5 Restrict Survival of Avirulent Type III Strains of Toxoplasma gondii in Naive Macrophages
Sumit K. Matta, Kelley Patten, Quiling Wang, Bae-Hoon Kim, John D. MacMicking, L. David Sibley
mBio. 2018 Jul-Aug; 9(4): e01393-18. Published online 2018 Aug 28. doi: 10.1128/mBio.01393-18
PMCID:
PMC6113620
AbstractArticlePDF–2.1M
13.
LPS targets host guanylate‐binding proteins to the bacterial outer membrane for non‐canonical inflammasome activation
José Carlos Santos, Mathias S Dick, Brice Lagrange, Daniel Degrandi, Klaus Pfeffer, Masahiro Yamamoto, Etienne Meunier, Pawel Pelczar, Thomas Henry, Petr Broz
EMBO J. 2018 Mar 15; 37(6): e98089. Published online 2018 Feb 19. doi: 10.15252/embj.201798089
PMCID:
PMC5852652
AbstractArticlePDF–2.3M
14.
Genetic Regulation of Guanylate-Binding Proteins 2b and 5 during Leishmaniasis in Mice
Yahya Sohrabi, Valeryia Volkova, Tatyana Kobets, Helena Havelková, Imtissal Krayem, Martina Slapničková, Peter Demant, Marie Lipoldová
Front Immunol. 2018; 9: 130. Published online 2018 Feb 7. doi: 10.3389/fimmu.2018.00130
PMCID:
PMC5808352
AbstractArticlePDF–4.5M
15.
IRGB10 liberates bacterial ligands for sensing by the AIM2 and caspase-11–NLRP3 inflammasomes
Si Ming Man, Rajendra Karki, Miwa Sasai, David E. Place, Sannula Kesavardhana, Jamshid Temirov, Sharon Frase, Qifan Zhu, R.K. Subbarao Malireddi, Teneema Kuriakose, Jennifer L. Peters, Geoffrey Neale, Scott A. Brown, Masahiro Yamamoto, Thirumala-Devi Kanneganti
Cell. Author manuscript; available in PMC 2017 Oct 6.
Published in final edited form as: Cell. 2016 Oct 6; 167(2): 382–396.e17. Published online 2016 Sep 29. doi: 10.1016/j.cell.2016.09.012
PMCID:
PMC5074697
AbstractArticlePDF–3.5M
16.
Guanylate-binding proteins promote AIM2 inflammasome activation during Francisella novicida infection by inducing cytosolic bacteriolysis and DNA release
Etienne Meunier, Pierre Wallet, Roland F. Dreier, Stéphanie Costanzo, Leonie Anton, Sebastian Rühl, Sébastien Dussurgey, Mathias S. Dick, Anne Kistner, Mélanie Rigard, Daniel Degrandi, Klaus Pfeffer, Masahiro Yamamoto, Thomas Henry, Petr Broz
Nat Immunol. Author manuscript; available in PMC 2015 Nov 1.
Published in final edited form as: Nat Immunol. 2015 May; 16(5): 476–484. Published online 2015 Mar 16. doi: 10.1038/ni.3119
PMCID:
PMC4568307
AbstractArticlePDF–2.2M
17.
The transcription factor IRF1 and guanylate-binding proteins target AIM2 inflammasome activation by Francisella infection
Si Ming Man, Rajendra Karki, R.K. Subbarao Malireddi, Geoffrey Neale, Peter Vogel, Masahiro Yamamoto, Mohamed Lamkanfi, Thirumala-Devi Kanneganti
Nat Immunol. Author manuscript; available in PMC 2015 Nov 1.
Published in final edited form as: Nat Immunol. 2015 May; 16(5): 467–475. Published online 2015 Mar 16. doi: 10.1038/ni.3118
PMCID:
PMC4406811
AbstractArticlePDF–1.5M
18.
Guanylate binding proteins promote caspase-11–dependent pyroptosis in response to cytoplasmic LPS
Danielle M. Pilla, Jon A. Hagar, Arun K. Haldar, Ashley K. Mason, Daniel Degrandi, Klaus Pfeffer, Robert K. Ernst, Masahiro Yamamoto, Edward A. Miao, Jörn Coers
Proc Natl Acad Sci U S A. 2014 Apr 22; 111(16): 6046–6051. Published online 2014 Apr 8. doi: 10.1073/pnas.1321700111
PMCID:
PMC4000848
AbstractArticlePDF–859K
19.
A conditional knockout resource for the genome–wide study of mouse gene function
William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley
Nature. Author manuscript; available in PMC 2013 Feb 14.
Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163
PMCID:
PMC3572410
AbstractArticlePDF–1.1M
20.
Impact of lactobacilli on orally acquired listeriosis
Cristel Archambaud, Marie-Anne Nahori, Guillaume Soubigou, Christophe Bécavin, Laure Laval, Pierre Lechat, Tamara Smokvina, Philippe Langella, Marc Lecuit, Pascale Cossart
Proc Natl Acad Sci U S A. 2012 Oct 9; 109(41): 16684–16689. Published online 2012 Sep 24. doi: 10.1073/pnas.1212809109
PMCID:
PMC3478606
AbstractArticlePDF–772K

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