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Select item 112109311.

CLU (clusterin) and PPARGC1A/PGC1α coordinately control mitophagy and mitochondrial biogenesis for oral cancer cell survival

Prakash P. Praharaj, Srimanta Patra, Amruta Singh, Debasna P. Panigrahi, Hwa Y. Lee, Mohammad F. Kabir, Muhammad K. Hossain, Samir K. Patra, Birija S. Patro, Shankargouda Patil, Daniel J. Klionsky, Han J. Chae, Sujit K. Bhutia

Autophagy. 2024; 20(6): 1359–1382. Published online 2024 Mar 6. doi: 10.1080/15548627.2024.2309904

PMCID:: PMC11210931

Abstract Article PDF–12M

Select item 111442682.

PGC-1α repression dysregulates lipid metabolism and induces lipid droplet accumulation in the retinal pigment epithelium

Shuyan Zhou, Kaan Taskintuna, Jacob Hum, Jasmine Gulati, Stephanie Olaya, Jeremy Steinman, Nady Golestaneh

Cell Death Dis. 2024 Jun; 15(6): 385. Published online 2024 Jun 1. doi: 10.1038/s41419-024-06762-y

PMCID:: PMC11144268

Abstract Article PDF–13M

Select item 109044933.

Skeletal muscle TET3 promotes insulin resistance through destabilisation of PGC-1α

Beibei Liu, Di Xie, Xinmei Huang, Sungho Jin, Yangyang Dai, Xiaoli Sun, Da Li, Anton M. Bennett, Sabrina Diano, Yingqun Huang

Diabetologia. 2024; 67(4): 724–737. Published online 2024 Jan 13. doi: 10.1007/s00125-023-06073-5

PMCID:: PMC10904493

Abstract Article PDF–1.4M

Select item 107727424.

Association of Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1 Alpha Coding Variants with Hepatocellular Carcinoma Risk in the Moroccan Population: A Case-Control Study

Ikram-Allah Tanouti, Hassan Fellah, Raouia El Fihry, Chaimaa Zerrad, Karima Abounouh, Mohamed Tahiri, Abdelkader Belkouchi, Wafaa Badre, Pascal Pineau, Soumaya Benjelloun, Sayeh Ezzikouri

Asian Pac J Cancer Prev. 2023; 24(11): 3689–3696. doi: 10.31557/APJCP.2023.24.11.3689

PMCID:: PMC10772742

Abstract Article PDF–492K

Select item 107180155.

ACE I/D, ACTN3 R577X, PPARD T294C and PPARGC1AGly482Ser polymorphisms and physical fitness in Taiwanese late adolescent girls

Li-Ling Chiu, Tzu-Wen Chen, Sandy S. Hsieh, Ling-Ling Hsieh

J Physiol Sci. 2012 Mar; 62(2): 115–121. Published online 2012 Jan 14. doi: 10.1007/s12576-011-0189-0

PMCID:: PMC10718015

Abstract Article PDF–220K

Select item 107180116.

Exercise-induced expression of peroxisome proliferator-activated receptor γ coactivator-1α isoforms in skeletal muscle of endurance-trained males

Daniil V. Popov, Anton V. Bachinin, Evgeny A. Lysenko, Tatiana F. Miller, Olga L. Vinogradova

J Physiol Sci. 2014 Sep; 64(5): 317–323. Published online 2014 Jun 7. doi: 10.1007/s12576-014-0321-z

PMCID:: PMC10718011

Abstract Article PDF–486K

Select item 107174797.

Peroxisome proliferator-activated receptor gamma co-activator 1 gene Gly482Ser polymorphism is associated with the response of low-density lipoprotein cholesterol concentrations to exercise training in elderly Japanese

Takuro Tobina, Yukari Mori, Yukiko Doi, Fuki Nakayama, Akira Kiyonaga, Hiroaki Tanaka

J Physiol Sci. 2017 Sep; 67(5): 595–602. Published online 2016 Oct 3. doi: 10.1007/s12576-016-0491-y

PMCID:: PMC10717479

Abstract Article PDF–526K

Select item 105775328.

AAV‐Mediated nuclear localized PGC1α4 delivery in muscle ameliorates sarcopenia and aging‐associated metabolic dysfunctions

Mingwei Guo, Jun Zhang, Ying Ma, Zhenzhong Zhu, Hui Zuo, Jing Yao, Xia Wu, Dongmei Wang, Jian Yu, Meiyao Meng, Caizhi Liu, Yi Zhang, Jiangrong Chen, Jian Lu, Shuzhe Ding, Cheng Hu, Xinran Ma, Lingyan Xu

Aging Cell. 2023 Oct; 22(10): e13961. Published online 2023 Aug 16. doi: 10.1111/acel.13961

PMCID:: PMC10577532

Abstract Article PDF–12M

Select item 104850269.

The master energy homeostasis regulator PGC-1α exhibits an mRNA nuclear export function

Simeon R. Mihaylov, Lydia M. Castelli, Ya-Hui Lin, Aytac Gül, Nikita Soni, Christopher Hastings, Helen R. Flynn, Oana Păun, Mark J. Dickman, Ambrosius P. Snijders, Robert Goldstone, Oliver Bandmann, Tatyana A. Shelkovnikova, Heather Mortiboys, Sila K. Ultanir, Guillaume M. Hautbergue

Nat Commun. 2023; 14: 5496. Published online 2023 Sep 7. doi: 10.1038/s41467-023-41304-8

PMCID:: PMC10485026

Abstract Article PDF–5.0M

Select item 1047546310.

Knockdown of PGC1α suppresses dysplastic oral keratinocytes proliferation through reprogramming energy metabolism

Yunkun Liu, Nengwen Huang, Xianghe Qiao, Zhiyu Gu, Yongzhi Wu, Jinjin Li, Chengzhou Wu, Bo Li, Longjiang Li

Int J Oral Sci. 2023; 15: 37. Published online 2023 Sep 4. doi: 10.1038/s41368-023-00242-3

PMCID:: PMC10475463

Abstract Article PDF–2.7M

Select item 1024428711.

Engineered allele substitution at PPARGC1A rs8192678 alters human white adipocyte differentiation, lipogenesis, and PGC-1α content and turnover

Mi Huang, Melina Claussnitzer, Alham Saadat, Daniel E. Coral, Sebastian Kalamajski, Paul W. Franks

Diabetologia. 2023; 66(7): 1289–1305. Published online 2023 May 12. doi: 10.1007/s00125-023-05915-6

PMCID:: PMC10244287

Abstract Article PDF–13M

Select item 1024187912.

Epigenetic suppression of PGC1α (PPARGC1A) causes collateral sensitivity to HMGCR-inhibitors within BRAF-treatment resistant melanomas

Jiaxin Liang, Deyang Yu, Chi Luo, Christopher Bennett, Mark Jedrychowski, Steve P. Gygi, Hans R. Widlund, Pere Puigserver

Nat Commun. 2023; 14: 3251. Published online 2023 Jun 5. doi: 10.1038/s41467-023-38968-7

PMCID:: PMC10241879

Abstract Article PDF–2.7M

Select item 1013825513.

Association between the PPARGC1A Gly482Ser polymorphism and muscle fitness in Chinese schoolchildren

Qi Wei

PLoS One. 2023; 18(4): e0284827. Published online 2023 Apr 27. doi: 10.1371/journal.pone.0284827

PMCID:: PMC10138255

Abstract Article PDF–533K

Select item 996840414.

Evidence of SARS-CoV-2 infection in postmortem lung, kidney, and liver samples, revealing cellular targets involved in COVID-19 pathogenesis

Viviana Falcón-Cama, Teresita Montero-González, Emilio F. Acosta-Medina, Gerardo Guillen-Nieto, Jorge Berlanga-Acosta, Celia Fernández-Ortega, Anabel Alfonso-Falcón, Nathalie Gilva-Rodríguez, Lilianne López-Nocedo, Daina Cremata-García, Mariuska Matos-Terrero, Giselle Pentón-Rol, Iris Valdés, Leonardo Oramas-Díaz, Anamarys Suarez-Batista, Enrique Noa-Romero, Otto Cruz-Sui, Daisy Sánchez, Amanda I. Borrego-Díaz, Juan E. Valdés-Carreras, Ananayla Vizcaino, José Suárez-Alba, Rodolfo Valdés-Véliz, Gretchen Bergado, Miguel A. González, Tays Hernandez, Rydell Alvarez-Arzola, Anna C. Ramírez-Suárez, Dionne Casillas-Casanova, Gilda Lemos-Pérez, Omar R. Blanco-Águila, Angelina Díaz, Yorexis González, Mónica Bequet-Romero, Javier Marín-Prida, Julio C. Hernández-Perera, Leticia del Rosario-Cruz, Alina P. Marin-Díaz, Maritza González-Bravo, Israel Borrajero, Nelson Acosta-Rivero

Arch Virol. 2023; 168(3): 96. Published online 2023 Feb 26. doi: 10.1007/s00705-023-05711-y

PMCID:: PMC9968404

Abstract Article PDF–3.2M

Select item 982046015.

The Hippocampal Response to Acute Corticosterone Elevation Is Altered in a Mouse Model for Angelman Syndrome

Eva M. G. Viho, A. Mattijs Punt, Ben Distel, René Houtman, Jan Kroon, Ype Elgersma, Onno C. Meijer

Int J Mol Sci. 2023 Jan; 24(1): 303. Published online 2022 Dec 24. doi: 10.3390/ijms24010303

PMCID:: PMC9820460

Abstract Article PDF–3.4M

Select item 980519916.

Association between PPARγ, PPARGC1A, and PPARGC1B genetic variants and susceptibility of gastric cancer in an Eastern Chinese population

Boyang Chen, Yafeng Wang, Weifeng Tang, Yu Chen, Chao Liu, Mingqiang Kang, Jinbiao Xie

BMC Med Genomics. 2022; 15: 274. Published online 2022 Dec 31. doi: 10.1186/s12920-022-01428-0

PMCID:: PMC9805199

Abstract Article PDF–944K

Select item 974187917.

Analysis of Metabolic Regulators PGC1-α and PGC1-β in Oral Squamous Cell Carcinoma with and without Hyperglycemia

Tamizh Paavai Thamizhanambi, Annasamy Rameshkumar, Ramadoss Ramya, Rajkumar Krishnan, Thayalan Dineshkumar, Gunasekaran Nandhini

Asian Pac J Cancer Prev. 2022 Aug; 23(8): 2797–2803. doi: 10.31557/APJCP.2022.23.8.2797

PMCID:: PMC9741879

Abstract Article PDF–332K

Select item 970928218.

Effects of PPARG and PPARGC1A gene polymorphisms on obesity markers

Carmen Muntean, Maria Oana Sasaran, Adriana Crisan, Claudia Banescu

Front Public Health. 2022; 10: 962852. Published online 2022 Nov 16. doi: 10.3389/fpubh.2022.962852

PMCID:: PMC9709282

Abstract Article PDF–331K

Select item 969413119.

Association of Irisin/FNDC5 with ERRα and PGC-1α Expression in NSCLC

Katarzyna Nowińska, Karolina Jabłońska, Urszula Ciesielska, Aleksandra Piotrowska, Katarzyna Haczkiewicz-Leśniak, Konrad Pawełczyk, Marzenna Podhorska-Okołów, Piotr Dzięgiel

Int J Mol Sci. 2022 Nov; 23(22): 14204. Published online 2022 Nov 17. doi: 10.3390/ijms232214204

PMCID:: PMC9694131

Abstract Article PDF–7.6M

Select item 968806220.

Survival Pathways of HIF-Deficient Tumour Cells: TCA Inhibition, Peroxisomal Fatty Acid Oxidation Activation and an AMPK-PGC-1α Hypoxia Sensor

Monika A. Golinska, Marion Stubbs, Adrian L. Harris, Laszlo G. Boros, Madhu Basetti, Dominick J. O. McIntyre, John R. Griffiths

Cells. 2022 Nov; 11(22): 3595. Published online 2022 Nov 14. doi: 10.3390/cells11223595

PMCID:: PMC9688062

Abstract Article PDF–3.6M

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