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Items: 1 to 20 of 129

1.
Structural basis of telomeric nucleosome recognition by shelterin factor TRF1
Hongmiao Hu, Anne-Marie M. van Roon, George E. Ghanim, Bilal Ahsan, Abraham O. Oluwole, Sew-Yeu Peak-Chew, Carol V. Robinson, Thi Hoang Duong Nguyen
Sci Adv. 2023 Aug; 9(34): eadi4148. Published online 2023 Aug 25. doi: 10.1126/sciadv.adi4148
PMCID:
PMC10456876
AbstractArticlePDF–2.0M
2.
The histone acetyltransferase KAT6A is recruited to unmethylated CpG islands via a DNA binding winged helix domain
Lisa Marie Weber, Yulin Jia, Bastian Stielow, Stephen S Gisselbrecht, Yinghua Cao, Yanpeng Ren, Iris Rohner, Jessica King, Elisabeth Rothman, Sabrina Fischer, Clara Simon, Ignasi Forné, Andrea Nist, Thorsten Stiewe, Martha L Bulyk, Zhanxin Wang, Robert Liefke
Nucleic Acids Res. 2023 Jan 25; 51(2): 574–594. Published online 2022 Dec 20. doi: 10.1093/nar/gkac1188
PMCID:
PMC9881136
AbstractArticlePDF–4.4M
3.
A proteome-scale map of the SARS-CoV-2–human contactome
Dae-Kyum Kim, Benjamin Weller, Chung-Wen Lin, Dayag Sheykhkarimli, Jennifer J. Knapp, Guillaume Dugied, Andreas Zanzoni, Carles Pons, Marie J. Tofaute, Sibusiso B. Maseko, Kerstin Spirohn, Florent Laval, Luke Lambourne, Nishka Kishore, Ashyad Rayhan, Mayra Sauer, Veronika Young, Hridi Halder, Nora Marín-de la Rosa, Oxana Pogoutse, Alexandra Strobel, Patrick Schwehn, Roujia Li, Simin T. Rothballer, Melina Altmann, Patricia Cassonnet, Atina G. Coté, Lena Elorduy Vergara, Isaiah Hazelwood, Betty B. Liu, Maria Nguyen, Ramakrishnan Pandiarajan, Bushra Dohai, Patricia A. Rodriguez Coloma, Juline Poirson, Paolo Giuliana, Luc Willems, Mikko Taipale, Yves Jacob, Tong Hao, David E. Hill, Christine Brun, Jean-Claude Twizere, Daniel Krappmann, Matthias Heinig, Claudia Falter, Patrick Aloy, Caroline Demeret, Marc Vidal, Michael A. Calderwood, Frederick P. Roth, Pascal Falter-Braun
Nat Biotechnol. 2023; 41(1): 140–149. Published online 2022 Oct 10. doi: 10.1038/s41587-022-01475-z
PMCID:
PMC9849141
AbstractArticlePDF–7.1M
4.
In Vitro Characterization of the Physical Interactions between the Long Noncoding RNA TERRA and the Telomeric Proteins TRF1 and TRF2
Patricia L. Abreu, Yong Woo Lee, Claus M. Azzalin
Int J Mol Sci. 2022 Sep; 23(18): 10463. Published online 2022 Sep 9. doi: 10.3390/ijms231810463
PMCID:
PMC9500956
AbstractArticlePDF–2.3M
5.
Chr21 protein–protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer’s disease
Julia Viard, Yann Loe-Mie, Rachel Daudin, Malik Khelfaoui, Christine Plancon, Anne Boland, Francisco Tejedor, Richard L Huganir, Eunjoon Kim, Makoto Kinoshita, Guofa Liu, Volker Haucke, Thomas Moncion, Eugene Yu, Valérie Hindie, Henri Bléhaut, Clotilde Mircher, Yann Herault, Jean-François Deleuze, Jean-Christophe Rain, Michel Simonneau, Aude-Marie Lepagnol-Bestel
Life Sci Alliance. 2022 Dec; 5(12): e202101205. Published online 2022 Aug 1. doi: 10.26508/lsa.202101205
PMCID:
PMC9348576
AbstractArticlePDF–3.0M
6.
The E3 ubiquitin ligase HECTD1 contributes to cell proliferation through an effect on mitosis
Natalie Vaughan, Nico Scholz, Catherine Lindon, Julien D. F. Licchesi
Sci Rep. 2022; 12: 13160. Published online 2022 Aug 1. doi: 10.1038/s41598-022-16965-y
PMCID:
PMC9343455
AbstractArticlePDF–3.7M
7.
Compartmentalization of Telomeres through DNA-scaffolded Phase Separation
Amanda Jack, Yoonji Kim, Amy R. Strom, Daniel S.W. Lee, Byron Williams, Jeffrey M. Schaub, Elizabeth H. Kellogg, Ilya J. Finkelstein, Luke S. Ferro, Ahmet Yildiz, Clifford P. Brangwynne
Dev Cell. Author manuscript; available in PMC 2022 Apr 24.
Published in final edited form as: Dev Cell. 2022 Jan 24; 57(2): 277–290.e9. doi: 10.1016/j.devcel.2021.12.017
PMCID:
PMC8988007
AbstractArticlePDF–2.6M
8.
CRL4AMBRA1 is a master regulator of D-type cyclins
Daniele Simoneschi, Gergely Rona, Nan Zhou, Yeon-Tae Jeong, Shaowen Jiang, Giacomo Milletti, Arnaldo A. Arbini, Alfie O’Sullivan, Andrew A. Wang, Sorasicha Nithikasem, Sarah Keegan, Yik Siu, Valentina Cianfanelli, Emiliano Maiani, Francesca Nazio, Francesco Cecconi, Francesco Boccalatte, David Fenyö, Drew R. Jones, Luca Busino, Michele Pagano
Nature. Author manuscript; available in PMC 2022 Apr 14.
Published in final edited form as: Nature. 2021 Apr; 592(7856): 789–793. Published online 2021 Apr 14. doi: 10.1038/s41586-021-03445-y
PMCID:
PMC8875297
AbstractArticlePDF–6.0M
9.
Global and transcription-coupled repair of 8-oxoG is initiated by nucleotide excision repair proteins
Namrata Kumar, Arjan F. Theil, Vera Roginskaya, Yasmin Ali, Michael Calderon, Simon C. Watkins, Ryan P. Barnes, Patricia L. Opresko, Alex Pines, Hannes Lans, Wim Vermeulen, Bennett Van Houten
Nat Commun. 2022; 13: 974. Published online 2022 Feb 21. doi: 10.1038/s41467-022-28642-9
PMCID:
PMC8861037
AbstractArticlePDF–6.2M
10.
Structure, dynamics, and regulation of TRF1-TIN2-mediated trans- and cis-interactions on telomeric DNA
Hai Pan, Parminder Kaur, Ryan Barnes, Ariana C. Detwiler, Samantha Lynn Sanford, Ming Liu, Pengning Xu, Chelsea Mahn, Qingyu Tang, Pengyu Hao, Dhruv Bhattaram, Changjiang You, Xinyun Gu, Warren Lu, Jacob Piehler, Guozhou Xu, Keith Weninger, Robert Riehn, Patricia L. Opresko, Hong Wang
J Biol Chem. 2021 Sep; 297(3): 101080. Published online 2021 Aug 14. doi: 10.1016/j.jbc.2021.101080
PMCID:
PMC8437784
AbstractArticlePDF–5.3M
11.
SLX4IP promotes RAP1 SUMOylation by PIAS1 to coordinate telomere maintenance through NF-κB and Notch signaling
Nathaniel J. Robinson, Masaru Miyagi, Jessica A. Scarborough, Jacob G. Scott, Derek J. Taylor, William P. Schiemann
Sci Signal. Author manuscript; available in PMC 2021 Dec 29.
Published in final edited form as: Sci Signal. 2021 Jun 29; 14(689): eabe9613. Published online 2021 Jun 29. doi: 10.1126/scisignal.abe9613
PMCID:
PMC8353884
AbstractArticlePDF–2.9M
12.
BRCA1 binds TERRA RNA and suppresses R-Loop-based telomeric DNA damage
Jekaterina Vohhodina, Liana J. Goehring, Ben Liu, Qing Kong, Vladimir V. Botchkarev Jr., Mai Huynh, Zhiqi Liu, Fieda O. Abderazzaq, Allison P. Clark, Scott B. Ficarro, Jarrod A. Marto, Elodie Hatchi, David M. Livingston
Nat Commun. 2021; 12: 3542. Published online 2021 Jun 10. doi: 10.1038/s41467-021-23716-6
PMCID:
PMC8192922
AbstractArticlePDF–7.6M
13.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
14.
DNA Repair Network Analysis Reveals Shieldin as a Key Regulator of NHEJ and PARP Inhibitor Sensitivity
Rajat Gupta, Kumar Somyajit, Takeo Narita, Elina Maskey, Andre Stanlie, Magdalena Kremer, Dimitris Typas, Michael Lammers, Niels Mailand, Andre Nussenzweig, Jiri Lukas, Chunaram Choudhary
Cell. Author manuscript; available in PMC 2021 May 10.
Published in final edited form as: Cell. 2018 May 3; 173(4): 972–988.e23. Published online 2018 Apr 12. doi: 10.1016/j.cell.2018.03.050
PMCID:
PMC8108093
AbstractArticlePDF–3.5M
15.
Low frequency variants associated with leukocyte telomere length in the Singapore Chinese population
Xuling Chang, Resham L. Gurung, Ling Wang, Aizhen Jin, Zheng Li, Renwei Wang, Kenneth B. Beckman, Jennifer Adams-Haduch, Wee Yang Meah, Kar Seng Sim, Weng Khong Lim, Sonia Davila, Patrick Tan, Jing Xian Teo, Khung Keong Yeo, Yiamunaa M., Sylvia Liu, Su Chi Lim, Jianjun Liu, Rob M. van Dam, Yechiel Friedlander, Woon-Puay Koh, Jian-Min Yuan, Chiea Chuen Khor, Chew-Kiat Heng, Rajkumar Dorajoo
Commun Biol. 2021; 4: 519. Published online 2021 May 3. doi: 10.1038/s42003-021-02056-7
PMCID:
PMC8093266
AbstractArticlePDF–1009K
16.
Dynamics of TRF1 organizing a single human telomere
Xu Li, Meijie Wang, Wei Zheng, Wei Huang, Zeyu Wang, Kairang Jin, Lin Liu, Zhongbo Yu
Nucleic Acids Res. 2021 Jan 25; 49(2): 760–775. Published online 2020 Dec 21. doi: 10.1093/nar/gkaa1222
PMCID:
PMC7826288
AbstractArticlePDF–3.2M
17.
In silico APC/C substrate discovery reveals cell cycle-dependent degradation of UHRF1 and other chromatin regulators
Jennifer L. Franks, Raquel C. Martinez-Chacin, Xianxi Wang, Rochelle L. Tiedemann, Thomas Bonacci, Rajarshi Choudhury, Derek L. Bolhuis, Taylor P. Enrico, Ryan D. Mouery, Jeffrey S. Damrauer, Feng Yan, Joseph S. Harrison, M. Ben Major, Katherine A. Hoadley, Aussie Suzuki, Scott B. Rothbart, Nicholas G. Brown, Michael J. Emanuele
PLoS Biol. 2020 Dec; 18(12): e3000975. Published online 2020 Dec 11. doi: 10.1371/journal.pbio.3000975
PMCID:
PMC7758050
AbstractArticlePDF–4.2M
18.
TERF1 downregulation promotes the migration and invasion of the PC3 prostate cancer cell line as a target of miR-155
Wei Chen, Li-Na He, Yong Liang, Xiang Zeng, Cui-Ping Wu, Ming-Qiang Su, Yang Cheng, Jian-Hui Liu
Mol Med Rep. 2020 Dec; 22(6): 5209–5218. Published online 2020 Oct 21. doi: 10.3892/mmr.2020.11623
PMCID:
PMC7646979
AbstractArticlePDF–1.2M
19.
Mutual regulation between OGT and XIAP to control colon cancer cell growth and invasion
Hyeon Gyu Seo, Han Byeol Kim, Ji Young Yoon, Tae Hyun Kweon, Yun Soo Park, Jingu Kang, Jinwoo Jung, SeongJin Son, Eugene C. Yi, Tae Ho Lee, Won Ho Yang, Jin Won Cho
Cell Death Dis. 2020 Sep; 11(9): 815. Published online 2020 Sep 29. doi: 10.1038/s41419-020-02999-5
PMCID:
PMC7525441
AbstractArticlePDF–3.7M
20.
Association of Relative Leucocyte Telomere Length and Gene Single Nucleotide Polymorphisms (TERT, TRF1, TNKS2) in Laryngeal Squamous Cell Carcinoma
PAULIUS VAICIULIS, RASA LIUTKEVICIENE, VYKINTAS LIUTKEVICIUS, ALVITA VILKEVICIUTE, GRETA GEDVILAITE, VIRGILIJUS ULOZA
Cancer Genomics Proteomics. 2020 Jul-Aug; 17(4): 431–439. Published online 2020 Jul 3. doi: 10.21873/cgp.20202
PMCID:
PMC7367600
AbstractArticlePDF–193K

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