PMC Links for GEO Profiles (Select 101643500) - PMC

Dóra Antal, Ágnes Pór, Ilona Kovács, Katalin Dull, Szilárd Póliska, Gyula Ujlaki, Máté Ágoston Demény, Attila Gábor Szöllősi, Borbála Kiss, Andrea Szegedi, Péter Bai, Magdolna Szántó

J Mol Med (Berl) 2023; 101(8): 987–999. Published online 2023 Jun 23. doi: 10.1007/s00109-023-02338-z

PMCID:: PMC10400701

Abstract Article PDF–3.5M

Select item 102374224.

TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing

Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan

Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233

PMCID:: PMC10237422

Abstract Article PDF–23M

Select item 102359825.

Single-molecule force spectroscopy reveals binding and bridging dynamics of PARP1 and PARP2 at DNA double-strand breaks

Nicholas A. W. Bell, Justin E. Molloy

Proc Natl Acad Sci U S A. 2023 May 30; 120(22): e2214209120. Published online 2023 May 22. doi: 10.1073/pnas.2214209120

PMCID:: PMC10235982

Abstract Article PDF–2.2M

Select item 99504476.

Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma

Yu-Fei Cao, Lei Xie, Bei-Bei Tong, Man-Yu Chu, Wen-Qi Shi, Xiang Li, Jian-Zhong He, Shao-Hong Wang, Zhi-Yong Wu, Dan-Xia Deng, Ya-Qi Zheng, Zhi-Mao Li, Xiu-E Xu, Lian-Di Liao, Yin-Wei Cheng, Li-Yan Li, Li-Yan Xu, En-Min Li

Cell Death Differ. 2023 Feb; 30(2): 527–543. Published online 2022 Dec 16. doi: 10.1038/s41418-022-01104-x

PMCID:: PMC9950447

Abstract Article PDF–8.4M

Select item 97979887.

TBK1 posphorylation activates LIR-dependent degradation of the inflammation repressor TNIP1

Jianwen Zhou, Nikoline Lander Rasmussen, Hallvard Lauritz Olsvik, Vyacheslav Akimov, Zehan Hu, Gry Evjen, Stéphanie Kaeser-Pebernard, Devanarayanan Siva Sankar, Carole Roubaty, Pauline Verlhac, Nicole van de Beek, Fulvio Reggiori, Yakubu Princely Abudu, Blagoy Blagoev, Trond Lamark, Terje Johansen, Jörn Dengjel

J Cell Biol. 2023 Feb 6; 222(2): e202108144. Published online 2022 Dec 27. doi: 10.1083/jcb.202108144

PMCID:: PMC9797988

Abstract Article PDF–6.9M

Select item 91197368.

OpenCell: proteome-scale endogenous tagging enables the cartography of human cellular organization

Nathan H. Cho, Keith C. Cheveralls, Andreas-David Brunner, Kibeom Kim, André C. Michaelis, Preethi Raghavan, Hirofumi Kobayashi, Laura Savy, Jason Y. Li, Hera Canaj, James Y.S. Kim, Edna M. Stewart, Christian Gnann, Frank McCarthy, Joana P. Cabrera, Rachel M. Brunetti, Bryant B. Chhun, Greg Dingle, Marco Y. Hein, Bo Huang, Shalin B. Mehta, Jonathan S. Weissman, Rafael Gómez-Sjöberg, Daniel N. Itzhak, Loic A. Royer, Matthias Mann, Manuel D. Leonetti

Science. Author manuscript; available in PMC 2022 Sep 11.

Published in final edited form as: Science. 2022 Mar 11; 375(6585): eabi6983. Published online 2022 Mar 11. doi: 10.1126/science.abi6983

PMCID:: PMC9119736

Abstract Article PDF–3.3M

Select item 86077499.

Temporal dynamics of base excision/single-strand break repair protein complex assembly/disassembly are modulated by the PARP/NAD⁺/SIRT6 axis

Christopher A. Koczor, Kate M. Saville, Joel F. Andrews, Jennifer Clark, Qingming Fang, Jianfeng Li, Rasha Q. Al-Rahahleh, Md Ibrahim, Steven McClellan, Mikhail V. Makarov, Marie E. Migaud, Robert W. Sobol

Cell Rep. Author manuscript; available in PMC 2021 Nov 22.

Published in final edited form as: Cell Rep. 2021 Nov 2; 37(5): 109917. doi: 10.1016/j.celrep.2021.109917

PMCID:: PMC8607749

Abstract Article PDF–2.2M

Select item 860237010.

HPF1 dynamically controls the PARP1/2 balance between initiating and elongating ADP-ribose modifications

Marie-France Langelier, Ramya Billur, Aleksandr Sverzhinsky, Ben E. Black, John M. Pascal

Nat Commun. 2021; 12: 6675. Published online 2021 Nov 18. doi: 10.1038/s41467-021-27043-8

PMCID:: PMC8602370

Abstract Article PDF–2.1M

Select item 856658311.

Dual function of HPF1 in the modulation of PARP1 and PARP2 activities

Tatyana A. Kurgina, Nina A. Moor, Mikhail M. Kutuzov, Konstantin N. Naumenko, Alexander A. Ukraintsev, Olga I. Lavrik

Commun Biol. 2021; 4: 1259. Published online 2021 Nov 3. doi: 10.1038/s42003-021-02780-0

PMCID:: PMC8566583

Abstract Article PDF–2.4M

Select item 824946412.

Serine-linked PARP1 auto-modification controls PARP inhibitor response

Evgeniia Prokhorova, Florian Zobel, Rebecca Smith, Siham Zentout, Ian Gibbs-Seymour, Kira Schützenhofer, Alessandra Peters, Joséphine Groslambert, Valentina Zorzini, Thomas Agnew, John Brognard, Michael L. Nielsen, Dragana Ahel, Sébastien Huet, Marcin J. Suskiewicz, Ivan Ahel

Nat Commun. 2021; 12: 4055. Published online 2021 Jul 1. doi: 10.1038/s41467-021-24361-9

PMCID:: PMC8249464

Abstract Article PDF–2.5M

Select item 822788413.

Silencing of Poly(ADP-Ribose) Polymerase-2 Induces Mitochondrial Reactive Species Production and Mitochondrial Fragmentation

Laura Jankó, Tünde Kovács, Miklós Laczik, Zsanett Sári, Gyula Ujlaki, Gréta Kis, Ibolya Horváth, Miklós Antal, László Vígh, Bálint L. Bálint, Karen Uray, Péter Bai

Cells. 2021 Jun; 10(6): 1387. Published online 2021 Jun 4. doi: 10.3390/cells10061387

PMCID:: PMC8227884

Abstract Article PDF–5.5M

Select item 819014214.

Activation of PARP2/ARTD2 by DNA damage induces conformational changes relieving enzyme autoinhibition

Ezeogo Obaji, Mirko M. Maksimainen, Albert Galera-Prat, Lari Lehtiö

Nat Commun. 2021; 12: 3479. Published online 2021 Jun 9. doi: 10.1038/s41467-021-23800-x

PMCID:: PMC8190142

Abstract Article PDF–3.1M

Select item 816503015.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 815071616.

PARP Power: A Structural Perspective on PARP1, PARP2, and PARP3 in DNA Damage Repair and Nucleosome Remodelling

Lotte van Beek, Éilís McClay, Saleha Patel, Marianne Schimpl, Laura Spagnolo, Taiana Maia de Oliveira

Int J Mol Sci. 2021 May; 22(10): 5112. Published online 2021 May 12. doi: 10.3390/ijms22105112

PMCID:: PMC8150716

Abstract Article PDF–5.0M

Select item 812481417.

Functional Roles of PARP2 in Assembling Protein–Protein Complexes Involved in Base Excision DNA Repair

Inna Vasil’eva, Nina Moor, Rashid Anarbaev, Mikhail Kutuzov, Olga Lavrik

Int J Mol Sci. 2021 May; 22(9): 4679. Published online 2021 Apr 28. doi: 10.3390/ijms22094679

PMCID:: PMC8124814

Abstract Article PDF–3.4M

Select item 792166318.

The contribution of PARP1, PARP2 and poly(ADP-ribosyl)ation to base excision repair in the nucleosomal context

M. M. Kutuzov, E. A. Belousova, T. A. Kurgina, A. A. Ukraintsev, I. A. Vasil’eva, S. N. Khodyreva, O. I. Lavrik

Sci Rep. 2021; 11: 4849. Published online 2021 Mar 1. doi: 10.1038/s41598-021-84351-1

PMCID:: PMC7921663

Abstract Article PDF–3.9M

Select item 791045919.

Combinatorial CRISPR screen identifies fitness effects of gene paralogues

Nicola A. Thompson, Marco Ranzani, Louise van der Weyden, Vivek Iyer, Victoria Offord, Alastair Droop, Fiona Behan, Emanuel Gonçalves, Anneliese Speak, Francesco Iorio, James Hewinson, Victoria Harle, Holly Robertson, Elizabeth Anderson, Beiyuan Fu, Fengtang Yang, Guido Zagnoli-Vieira, Phil Chapman, Martin Del Castillo Velasco-Herrera, Mathew J. Garnett, Stephen P. Jackson, David J. Adams

Nat Commun. 2021; 12: 1302. Published online 2021 Feb 26. doi: 10.1038/s41467-021-21478-9

PMCID:: PMC7910459

Abstract Article PDF–3.3M

Select item 760891420.

Bridging of nucleosome-proximal DNA double-strand breaks by PARP2 enhances its interaction with HPF1

Guillaume Gaullier, Genevieve Roberts, Uma M. Muthurajan, Samuel Bowerman, Johannes Rudolph, Jyothi Mahadevan, Asmita Jha, Purushka S. Rae, Karolin Luger

PLoS One. 2020; 15(11): e0240932. Published online 2020 Nov 3. doi: 10.1371/journal.pone.0240932

PMCID:: PMC7608914

Abstract Article PDF–2.6M

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PMC Links for GEO Profiles (Select 101643500) (74)
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Systemic lupus erythematosus CD3+ T cells
Systemic lupus erythematosus CD3+ T cells
Accession: GDS4719

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LACC1 laccase domain containing 1 [Homo sapiens]
LACC1 laccase domain containing 1 [Homo sapiens]
Gene ID:144811

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