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Select item 106554661.

Enzymology of Vertebrate Carotenoid Oxygenases

Earl H. Harrison, Rachel E. Kopec

Biochim Biophys Acta Mol Cell Biol Lipids. Author manuscript; available in PMC 2023 Nov 17.

Published in final edited form as: Biochim Biophys Acta Mol Cell Biol Lipids. 2020 Nov; 1865(11): 158653. Published online 2020 Feb 5. doi: 10.1016/j.bbalip.2020.158653

PMCID:: PMC10655466

Abstract Article PDF–1.2M

Select item 95696912.

Association of MARC1, ADCY5, and BCO1 Variants with the Lipid Profile, Suggests an Additive Effect for Hypertriglyceridemia in Mexican Adult Men

Berenice Rivera-Paredez, Diana I. Aparicio-Bautista, Anna D. Argoty-Pantoja, Nelly Patiño, Jeny Flores Morales, Jorge Salmerón, Guadalupe León-Reyes, Rafael Velázquez-Cruz

Int J Mol Sci. 2022 Oct; 23(19): 11815. Published online 2022 Oct 5. doi: 10.3390/ijms231911815

PMCID:: PMC9569691

Abstract Article PDF–1.3M

Select item 93948033.

Association of TGFB1 rs1800469 and BCMO1 rs6564851 with coronary heart disease and IL1B rs16944 with all-cause mortality in men from the Northern Ireland PRIME study

Rachel E. Mooney, Gerry J. Linden, Lewis Winning, Katie Linden, Frank Kee, Pascal P. McKeown, Jayne V. Woodside, Christopher C. Patterson, Gareth J. McKay

PLoS One. 2022; 17(8): e0273333. Published online 2022 Aug 22. doi: 10.1371/journal.pone.0273333

PMCID:: PMC9394803

Abstract Article PDF–824K

Select item 83071944.

Cullin 1 (CUL1) Promotes Primary Ciliogenesis through the Induction of Ubiquitin-Proteasome-Dependent Dvl2 Degradation

Sun-Ok Kim, Kyoung Sang Cho, Bo Yeon Kim, Kyung Ho Lee

Int J Mol Sci. 2021 Jul; 22(14): 7572. Published online 2021 Jul 15. doi: 10.3390/ijms22147572

PMCID:: PMC8307194

Abstract Article PDF–2.8M

Select item 81650305.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 74236396.

Evolutionary aspects and enzymology of metazoan carotenoid cleavage oxygenases

Eugenia Poliakov, Sheetal Uppal, Igor B. Rogozin, Susan Gentleman, T. Michael Redmond

Biochim Biophys Acta Mol Cell Biol Lipids. Author manuscript; available in PMC 2021 Nov 1.

Published in final edited form as: Biochim Biophys Acta Mol Cell Biol Lipids. 2020 Nov; 1865(11): 158665. Published online 2020 Feb 12. doi: 10.1016/j.bbalip.2020.158665

PMCID:: PMC7423639

Abstract Article PDF–1.0M

Select item 73987807.

β-Carotene Oxygenase 1 Activity Modulates Circulating Cholesterol Concentrations in Mice and Humans

Jaume Amengual, Johana Coronel, Courtney Marques, Celia Aradillas-García, Juan Manuel Vargas Morales, Flavia C D Andrade, John W Erdman, Jr, Margarita Teran-Garcia

J Nutr. 2020 Aug; 150(8): 2023–2030. Published online 2020 May 20. doi: 10.1093/jn/nxaa143

PMCID:: PMC7398780

Abstract Article PDF–415K

Select item 73532938.

SNP rs6564851 in the BCO1 Gene Is Associated with Varying Provitamin a Plasma Concentrations but Not with Retinol Concentrations among Adolescents from Rural Ghana

Sophie Graßmann, Olga Pivovarova-Ramich, Andrea Henze, Jens Raila, Yaw Ampem Amoako, Richard King Nyamekye, George Bedu-Addo, Frank P. Mockenhaupt, Matthias B. Schulze, Ina Danquah

Nutrients. 2020 Jun; 12(6): 1786. Published online 2020 Jun 16. doi: 10.3390/nu12061786

PMCID:: PMC7353293

Abstract Article PDF–1.2M

Select item 63983929.

Single Nucleotide Polymorphisms in β-Carotene Oxygenase 1 are Associated with Plasma Lycopene Responses to a Tomato-Soy Juice Intervention in Men with Prostate Cancer

Nancy E Moran, Jennifer M Thomas-Ahner, Jessica L Fleming, Joseph P McElroy, Rebecca Mehl, Elizabeth M Grainger, Ken M Riedl, Amanda E Toland, Steven J Schwartz, Steven K Clinton

J Nutr. 2019 Mar; 149(3): 381–397. Published online 2019 Feb 25. doi: 10.1093/jn/nxy304

PMCID:: PMC6398392

Abstract Article PDF–798K

Select item 590920910.

Dietary patterns, BCMO1 polymorphisms, and primary lung cancer risk in a Han Chinese population: a case-control study in Southeast China

Fei He, Ren-dong Xiao, Tao Lin, Wei-min Xiong, Qiu-ping Xu, Xu Li, Zhi-qiang Liu, Bao-chang He, Zhi-jian Hu, Lin Cai

BMC Cancer. 2018; 18: 445. Published online 2018 Apr 19. doi: 10.1186/s12885-018-4361-2

PMCID:: PMC5909209

Abstract Article PDF–595K

Select item 553161111.

Architecture of the human interactome defines protein communities and disease networks

Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper

Nature. Author manuscript; available in PMC 2017 Nov 17.

Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366

PMCID:: PMC5531611

Abstract Article PDF–2.7M

Select item 552177812.

Inhibition of pulmonary β-carotene 15, 15’-oxygenase expression by glucocorticoid involves PPARα

Xiaoming Gong, Raju Marisiddaiah, Lewis P. Rubin

PLoS One. 2017; 12(7): e0181466. Published online 2017 Jul 21. doi: 10.1371/journal.pone.0181466

PMCID:: PMC5521778

Abstract Article PDF–4.6M

Select item 517907513.

Common SNP rs6564851 in the BCO1 Gene Affects the Circulating Levels of β-Carotene and the Daily Intake of Carotenoids in Healthy Japanese Women

Suemi Yabuta, Masanori Urata, Roseline Yap Wai Kun, Motofumi Masaki, Yoshihiro Shidoji

PLoS One. 2016; 11(12): e0168857. Published online 2016 Dec 22. doi: 10.1371/journal.pone.0168857

PMCID:: PMC5179075

Abstract Article PDF–996K

Select item 403637014.

The Human Enzyme That Converts Dietary Provitamin A Carotenoids to Vitamin A Is a Dioxygenase

Carlo dela Seña, Kenneth M. Riedl, Sureshbabu Narayanasamy, Robert W. Curley, Jr., Steven J. Schwartz, Earl H. Harrison

J Biol Chem. 2014 May 9; 289(19): 13661–13666. Published online 2014 Mar 25. doi: 10.1074/jbc.M114.557710

PMCID:: PMC4036370

Abstract Article PDF–1.0M

Select item 392964415.

The Relationship between BCMO1 Gene Variants and Macular Pigment Optical Density in Persons with and without Age-Related Macular Degeneration

Beatrix Feigl, C. Phillip Morris, Joanne Voisey, Anthony Kwan, Andrew J. Zele

PLoS One. 2014; 9(2): e89069. Published online 2014 Feb 19. doi: 10.1371/journal.pone.0089069

PMCID:: PMC3929644

Abstract Article PDF–243K

Select item 387356516.

Substrate Specificity of Purified Recombinant Human β-Carotene 15,15′-Oxygenase (BCO1)

Carlo dela Seña, Sureshbabu Narayanasamy, Kenneth M. Riedl, Robert W. Curley, Jr., Steven J. Schwartz, Earl H. Harrison

J Biol Chem. 2013 Dec 27; 288(52): 37094–37103. Published online 2013 Nov 1. doi: 10.1074/jbc.M113.507160

PMCID:: PMC3873565

Abstract Article PDF–1.9M

Select item 383714917.

Two Carotenoid Oxygenases Contribute to Mammalian Provitamin A Metabolism

Jaume Amengual, M. Airanthi K. Widjaja-Adhi, Susana Rodriguez-Santiago, Susanne Hessel, Marcin Golczak, Krzysztof Palczewski, Johannes von Lintig

J Biol Chem. 2013 Nov 22; 288(47): 34081–34096. Published online 2013 Oct 8. doi: 10.1074/jbc.M113.501049

PMCID:: PMC3837149

Abstract Article PDF–2.8M

Select item 379599318.

Characterization of human β,β-carotene-15,15′-monooxygenase (BCMO1) as a soluble monomeric enzyme

Thomas Kowatz, Darwin Babino, Philip Kiser, Krzysztof Palczewski, Johannes von Lintig

Arch Biochem Biophys. Author manuscript; available in PMC 2014 Nov 15.

Published in final edited form as: Arch Biochem Biophys. 2013 Nov 15; 539(2): 10.1016/j.abb.2013.05.007. Published online 2013 May 29. doi: 10.1016/j.abb.2013.05.007

PMCID:: PMC3795993

Abstract Article PDF–1.6M

Select item 365373119.

Single nucleotide polymorphisms in CETP, SLC46A1, SLC19A1, CD36, BCMO1, APOA5, and ABCA1 are significant predictors of plasma HDL in healthy adults

Andrew J Clifford, Gonzalo Rincon, Janel E Owens, Juan F Medrano, Alanna J Moshfegh, David J Baer, Janet A Novotny

Lipids Health Dis. 2013; 12: 66. Published online 2013 May 8. doi: 10.1186/1476-511X-12-66

PMCID:: PMC3653731

Abstract Article PDF–258K

Select item 349792720.

β-Carotene 15,15′-monooxygenase 1 single nucleotide polymorphisms in relation to plasma carotenoid and retinol concentrations in women of European descent

Sara J Hendrickson, Aditi Hazra, Constance Chen, A Heather Eliassen, Peter Kraft, Bernard A Rosner, Walter C Willett

Am J Clin Nutr. 2012 Dec; 96(6): 1379–1389. Published online 2012 Nov 7. doi: 10.3945/ajcn.112.034934

PMCID:: PMC3497927

Abstract Article PDF–302K

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