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Select item 108553861.

Charged Amino Acids in the Transmembrane Helix Strongly Affect the Enzyme Activity of Aromatase

Juliane Günther, Gerhard Schuler, Elin Teppa, Rainer Fürbass

Int J Mol Sci. 2024 Feb; 25(3): 1440. Published online 2024 Jan 24. doi: 10.3390/ijms25031440

PMCID:: PMC10855386

Abstract Article PDF–4.6M

Select item 107221292.

SNP of Aromatase Predict Long-term Survival and Aromatase Inhibitor Toxicity in Patients with Early Breast Cancer: A Biomarker Analysis of the GIM4 and GIM5 Trials

Benedetta Conte, Luca Boni, Giancarlo Bisagni, Antonio Durando, Giovanni Sanna, Stefania Gori, Ornella Garrone, Stefano Tamberi, Sabino De Placido, Francesco Schettini, Antonio Pazzola, Riccardo Ponzone, Filippo Montemurro, Gianluigi Lunardi, Rosario Notaro, Maria De Angioletti, Anna Turletti, Mauro Mansutti, Fabio Puglisi, Antonio Frassoldati, Mauro Porpiglia, Alessandra Fabi, Daniele Generali, Giovanni Scognamiglio, Maura Rossi, Fara Brasó-Maristany, Aleix Prat, Barbara Cardinali, Patrizia Piccioli, Martina Serra, Sonia Lastraioli, Claudia Bighin, Francesca Poggio, Matteo Lambertini, Lucia Del Mastro

Clin Cancer Res. 2023 Dec 15; 29(24): 5217–5226. Published online 2023 Oct 27. doi: 10.1158/1078-0432.CCR-23-1568

PMCID:: PMC10722129

Abstract Article PDF–1.1M

Select item 105445463.

CYP19A1 promotes gastric cancer as part of a lipid metabolism-related gene signature related to the response of immunotherapy and prognosis

Xinyi Zhou, Fanyu Meng, Linmei Xiao, Hua Shen

BMC Med Genomics. 2023; 16: 228. Published online 2023 Oct 2. doi: 10.1186/s12920-023-01664-y

PMCID:: PMC10544546

Abstract Article PDF–13M

Select item 105186054.

CYP19A1 mediates severe SARS-CoV-2 disease outcome in males

Stephanie Stanelle-Bertram, Sebastian Beck, Nancy Kouassi Mounogou, Berfin Schaumburg, Fabian Stoll, Amirah Al Jawazneh, Zoé Schmal, Tian Bai, Martin Zickler, Georg Beythien, Kathrin Becker, Madeleine de la Roi, Fabian Heinrich, Claudia Schulz, Martina Sauter, Susanne Krasemann, Philine Lange, Axel Heinemann, Debby van Riel, Lonneke Leijten, Lisa Bauer, Thierry P.P. van den Bosch, Boaz Lopuhaä, Tobias Busche, Daniel Wibberg, Dirk Schaudien, Torsten Goldmann, Anna Lüttjohann, Jenny Ruschinski, Hanna Jania, Zacharias Müller, Vinicius Pinho dos Reis, Vanessa Krupp-Buzimkic, Martin Wolff, Chiara Fallerini, Margherita Baldassarri, Simone Furini, Katrina Norwood, Christopher Käufer, Nina Schützenmeister, Maren von Köckritz-Blickwede, Maria Schroeder, Dominik Jarczak, Axel Nierhaus, Tobias Welte, Stefan Kluge, Alice C. McHardy, Frank Sommer, Jörn Kalinowski, Susanne Krauss-Etschmann, Franziska Richter, Jan von der Thüsen, Wolfgang Baumgärtner, Karin Klingel, Benjamin Ondruschka, GEN-COVID Multicenter Study Group, Alessandra Renieri, Gülsah Gabriel

Cell Rep Med. 2023 Sep 19; 4(9): 101152. Published online 2023 Aug 12. doi: 10.1016/j.xcrm.2023.101152

PMCID:: PMC10518605

Abstract Article PDF–5.1M

Select item 104994825.

Genotype Frequencies of 50 Polymorphisms for 241 Japanese Non-cancer Patients

Nobuyuki Hamajima, Toshiko Saito, Keitaro Matsuo, Takashi Suzuki, Tsuneya Nakamura, Akio Matsuura, Katashi Okuma, Kazuo Tajima

J Epidemiol. 2002; 12(3): 229–236. Published online 2007 Nov 30. doi: 10.2188/jea.12.229

PMCID:: PMC10499482

Abstract Article PDF–588K

Select item 103580476.

CREB-Regulated Transcription Co-Activator Family Stimulates Promoter II-Driven Aromatase Expression in Preadipocytes

Nirukshi U. Samarajeewa, Maria M. Docanto, Evan R. Simpson, Kristy A. Brown

Horm Cancer. 2013 Aug; 4(4): 233–241. Published online 2013 Apr 13. doi: 10.1007/s12672-013-0142-1

PMCID:: PMC10358047

Abstract Article PDF–399K

Select item 103559127.

The Importance of CYP19A1 in Estrogen Receptor-Positive Cholangiocarcinoma

Waleeporn Kaewlert, Chadamas Sakonsinsiri, Nisana Namwat, Kanlayanee Sawanyawisuth, Piti Ungarreevittaya, Narong Khuntikeo, Napat Armartmuntree, Raynoo Thanan

Horm Cancer. 2018 Dec; 9(6): 408–419. Published online 2018 Oct 3. doi: 10.1007/s12672-018-0349-2

PMCID:: PMC10355912

Abstract Article PDF–8.0M

Select item 103094468.

Combined Effect of the PGR +331C > T, CYP17A1 -34A > G and CYP19A1 1531G > A Polymorphisms on the Risk of Developing Endometriosis

Jéssica Vilarinho Cardoso, Daniel Escorsim Machado, Renato Ferrari, Mayara Calixto da Silva, Plínio Tostes Berardo, Jamila Alessandra Perini

Rev Bras Ginecol Obstet. 2017 Jun; 39(6): 273–281. Published online 2017 Jun 14. doi: 10.1055/s-0037-1604097

PMCID:: PMC10309446

Abstract Article PDF–292K

Select item 97564599.

Association of CYP19A1 rs28757157 polymorphism with lung cancer risk in the Chinese Han population

Chan Zhang, Yujing Cheng, Wanlu Chen, Qi Li, Run Dai, Yajie Wang, Tonghua Yang

World J Surg Oncol. 2022; 20: 400. Published online 2022 Dec 16. doi: 10.1186/s12957-022-02868-9

PMCID:: PMC9756459

Abstract Article PDF–1.1M

Select item 946599710.

Aromatase expression in atypical ductal hyperplasia in women

R. J. Santen, D. C. Radisky, A. Degnim, M. H. Frost, C. M. Vachon, K. Ghosh, F. Guestini, K. M. McNamara, H. Sasano

Breast Cancer Res Treat. Author manuscript; available in PMC 2022 Sep 12.

Published in final edited form as: Breast Cancer Res Treat. 2017 Jun; 163(3): 623–629. Published online 2017 Mar 23. doi: 10.1007/s10549-017-4184-x

PMCID:: PMC9465997

Abstract Article PDF–1.0M

Select item 930227311.

Ursolic acid silences CYP19A1/aromatase to suppress gastric cancer growth

Wen‐Lung Ma, Ning Chang, Yingchun Yu, Yu‐Ting Su, Guan‐Yu Chen, Wei‐Chung Cheng, Yang‐Chang Wu, Ching‐Chia Li, Wei‐Chun Chang, Juan‐Cheng Yang

Cancer Med. 2022 Jul; 11(14): 2824–2835. Published online 2022 May 11. doi: 10.1002/cam4.4536

PMCID:: PMC9302273

Abstract Article PDF–2.6M

Select item 875604412.

The discrepancy of aromatase expression in epicardial adipose tissue between CHD and non-CHD patients

Yifan Li, Weiwei Cheng, Bin Zhao, Dongliang Ma, Xing Wei, Shunye Zhang

Cardiovasc J Afr. 2021 Jul-Aug; 32(4): 204–207. Published online 2021 Jun 7. doi: 10.5830/CVJA-2021-012

PMCID:: PMC8756044

Abstract Article PDF–83K

Select item 837208613.

The impact of CYP19A1 variants and haplotypes on breast cancer risk, clinicopathological features and prognosis

Ahmad Mohammed Alwan, Fahimeh Afzaljavan, Jalil Tavakol Afshari, Fatemeh Homaei Shandiz, Matineh Barati Bagherabad, Elham Vahednia, Nahid Kheradmand, Alireza Pasdar

Mol Genet Genomic Med. 2021 Jul; 9(7): e1705. Published online 2021 May 20. doi: 10.1002/mgg3.1705

PMCID:: PMC8372086

Abstract Article PDF–602K

Select item 836978214.

Identification of novel COX-2 / CYP19A1 axis involved in the mesothelioma pathogenesis opens new therapeutic opportunities

Barbara Nuvoli, Barbara Antoniani, Roberta Libener, Antonio Maconi, Andrea Sacconi, Mariantonia Carosi, Rossella Galati

J Exp Clin Cancer Res. 2021; 40: 257. Published online 2021 Aug 17. doi: 10.1186/s13046-021-02050-1

Correction in:: J Exp Clin Cancer Res. 2023; 42: 15.

PMCID:: PMC8369782

Abstract Article PDF–2.0M

Select item 826695815.

A threshold concentration of FSH is needed during IVM of ex vivo collected human oocytes

Jesús Cadenas, Dmitry Nikiforov, Susanne Elisabeth Pors, Lenin Arturo Zuniga, Yu Wakimoto, Zeinab Ghezelayagh, Linn Salto Mamsen, Stine Gry Kristensen, Claus Yding Andersen

J Assist Reprod Genet. 2021 Jun; 38(6): 1341–1348. Published online 2021 May 28. doi: 10.1007/s10815-021-02244-8

PMCID:: PMC8266958

Abstract Article PDF–562K

Select item 821756016.

Impact of rs2414096 polymorphism of CYP19 gene on susceptibility of polycystic ovary syndrome and hyperandrogenism in Kashmiri women

Sairish Ashraf, Shayaq Ul Abeer Rasool, Mudasar Nabi, Mohd Ashraf Ganie, Shariq R. Masoodi, Shajrul Amin

Sci Rep. 2021; 11: 12942. Published online 2021 Jun 21. doi: 10.1038/s41598-021-92265-1

PMCID:: PMC8217560

Abstract Article PDF–1.0M

Select item 816503017.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 811521418.

Estrogen Signaling and Portopulmonary Hypertension: The Pulmonary Vascular Complications of Liver Disease Study (PVCLD2)

Nadine Al-Naamani, Michael J. Krowka, Kimberly A. Forde, Karen L. Krok, Rui Feng, Gustavo A. Heresi, Raed A. Dweik, Sonja Bartolome, Todd M. Bull, Kari E. Roberts, Eric D. Austin, Anna R. Hemnes, Mamta J. Patel, Jae K. Oh, Grace Lin, Margaret F. Doyle, Nina Denver, Ruth Andrew, Margaret R. MacLean, Michael B. Fallon, Steven M. Kawut, Pulmonary Vascular Complications of Liver Disease Study Group

Hepatology. Author manuscript; available in PMC 2022 Feb 1.

Published in final edited form as: Hepatology. 2021 Feb; 73(2): 726–737. Published online 2020 Sep 29. doi: 10.1002/hep.31314

PMCID:: PMC8115214

Abstract Article PDF–663K

Select item 808062619.

Melatonin stimulates aromatase expression and estradiol production in human granulosa-lutein cells: relevance for high serum estradiol levels in patients with ovarian hyperstimulation syndrome

Jung-Chien Cheng, Lanlan Fang, Yiran Li, Sijia Wang, Yuxi Li, Yang Yan, Qiongqiong Jia, Ze Wu, Zhen Wang, Xiaoyu Han, Ying-Pu Sun

Exp Mol Med. 2020 Aug; 52(8): 1341–1350. Published online 2020 Aug 27. doi: 10.1038/s12276-020-00491-w

PMCID:: PMC8080626

Abstract Article PDF–1.3M

Select item 807390620.

Polymorphism on human aromatase affects protein dynamics and substrate binding: spectroscopic evidence

Giovanna Di Nardo, Almerinda Di Venere, Chao Zhang, Eleonora Nicolai, Silvia Castrignanò, Luisa Di Paola, Gianfranco Gilardi, Giampiero Mei

Biol Direct. 2021; 16: 8. Published online 2021 Apr 26. doi: 10.1186/s13062-021-00292-9

PMCID:: PMC8073906

Abstract Article PDF–1.7M

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