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Select item 105410181.

Transcription factor E4F1 as a regulator of cell life and disease progression

Silu Sun, Bing Zhong, Xin Zeng, Jing Li, Qianming Chen

Sci Adv. 2023 Sep 29; 9(39): eadh1991. Published online 2023 Sep 29. doi: 10.1126/sciadv.adh1991

PMCID:: PMC10541018

Abstract Article PDF–3.1M

Select item 94090402.

Multi-Level Control of the ATM/ATR-CHK1 Axis by the Transcription Factor E4F1 in Triple-Negative Breast Cancer

Kalil Batnini, Thibault Houles, Olivier Kirsh, Stanislas Du Manoir, Mehdi Zaroual, Hélène Delpech, Chloé Fallet, Matthieu Lacroix, Laurent Le Cam, Charles Theillet, Claude Sardet, Geneviève Rodier

Int J Mol Sci. 2022 Aug; 23(16): 9217. Published online 2022 Aug 16. doi: 10.3390/ijms23169217

PMCID:: PMC9409040

Abstract Article PDF–3.4M

Select item 86398903.

The multifunctional protein E4F1 links P53 to lipid metabolism in adipocytes

Matthieu Lacroix, Laetitia K. Linares, Natalia Rueda-Rincon, Katarzyna Bloch, Michela Di Michele, Carlo De Blasio, Caroline Fau, Laurie Gayte, Emilie Blanchet, Aline Mairal, Rita Derua, Fernando Cardona, Diane Beuzelin, Jean-Sebastien Annicotte, Nelly Pirot, Adeline Torro, Francisco J. Tinahones, Florence Bernex, Justine Bertrand-Michel, Dominique Langin, Lluis Fajas, Johannes V. Swinnen, Laurent Le Cam

Nat Commun. 2021; 12: 7037. Published online 2021 Dec 2. doi: 10.1038/s41467-021-27307-3

PMCID:: PMC8639890

Abstract Article PDF–5.9M

Select item 84056154.

CHFR regulates chemoresistance in triple-negative breast cancer through destabilizing ZEB1

Hong Luo, Zhicheng Zhou, Shan Huang, Mengru Ma, Manyu Zhao, Lixu Tang, Yuan Quan, Yiming Zeng, Li Su, Jongchan Kim, Peijing Zhang

Cell Death Dis. 2021 Sep; 12(9): 820. Published online 2021 Aug 30. doi: 10.1038/s41419-021-04114-8

PMCID:: PMC8405615

Abstract Article PDF–3.5M

Select item 81650305.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 79804446.

Zinc finger protein E4F1 cooperates with PARP-1 and BRG1 to promote DNA double-strand break repair

Céline Moison, Jalila Chagraoui, Marie-Christine Caron, Jean-Philippe Gagné, Yan Coulombe, Guy G. Poirier, Jean-Yves Masson, Guy Sauvageau

Proc Natl Acad Sci U S A. 2021 Mar 16; 118(11): e2019408118. Published online 2021 Mar 10. doi: 10.1073/pnas.2019408118

PMCID:: PMC7980444

Abstract Article PDF–2.0M

Select item 67468227.

The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei

Giovanni Nassa, Giorgio Giurato, Annamaria Salvati, Valerio Gigantino, Giovanni Pecoraro, Jessica Lamberti, Francesca Rizzo, Tuula A. Nyman, Roberta Tarallo, Alessandro Weisz

Sci Data. 2019; 6: 173. Published online 2019 Sep 16. doi: 10.1038/s41597-019-0179-2

PMCID:: PMC6746822

Abstract Article PDF–2.0M

Select item 64200978.

H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination in sister chromatids

Kyosuke Nakamura, Giulia Saredi, Jordan R. Becker, Benjamin M. Foster, Nhuong V. Nguyen, Tracey Beyer, Laura C. Cesa, Peter A. Faull, Saulius Lukauskas, Thomas Frimurer, J. Ross Chapman, Till Bartke, Anja Groth

Nat Cell Biol. Author manuscript; available in PMC 2019 Aug 25.

Published in final edited form as: Nat Cell Biol. 2019 Mar; 21(3): 311–318. Published online 2019 Feb 25. doi: 10.1038/s41556-019-0282-9

PMCID:: PMC6420097

Article PDF–1.7M

Select item 55316119.

Architecture of the human interactome defines protein communities and disease networks

Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper

Nature. Author manuscript; available in PMC 2017 Nov 17.

Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366

PMCID:: PMC5531611

Abstract Article PDF–2.7M

Select item 481716410.

Recruitment of the Mammalian Histone-modifying EMSY Complex to Target Genes Is Regulated by ZNF131

Radhika A. Varier, Enrique Carrillo de Santa Pau, Petra van der Groep, Rik G. H. Lindeboom, Filomena Matarese, Anneloes Mensinga, Arne H. Smits, Raghu Ram Edupuganti, Marijke P. Baltissen, Pascal W. T. C. Jansen, Natalie ter Hoeve, Danny R. van Weely, Ina Poser, Paul J. van Diest, Hendrik G. Stunnenberg, Michiel Vermeulen

J Biol Chem. 2016 Apr 1; 291(14): 7313–7324. Published online 2016 Feb 3. doi: 10.1074/jbc.M115.701227

PMCID:: PMC4817164

Abstract Article PDF–3.5M

Select item 433215011.

Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes

Xu Li, Wenqi Wang, Jiadong Wang, Anna Malovannaya, Yuanxin Xi, Wei Li, Rudy Guerra, David H Hawke, Jun Qin, Junjie Chen

Mol Syst Biol. 2015 Jan; 11(1): 775. Published online 2015 Jan 21. doi: 10.15252/msb.20145504

PMCID:: PMC4332150

Abstract Article PDF–2.8M

Select item 426658812.

A proteome-scale map of the human interactome network

Thomas Rolland, Murat Taşan, Benoit Charloteaux, Samuel J. Pevzner, Quan Zhong, Nidhi Sahni, Song Yi, Irma Lemmens, Celia Fontanillo, Roberto Mosca, Atanas Kamburov, Susan D. Ghiassian, Xinping Yang, Lila Ghamsari, Dawit Balcha, Bridget E. Begg, Pascal Braun, Marc Brehme, Martin P. Broly, Anne-Ruxandra Carvunis, Dan Convery-Zupan, Roser Corominas, Jasmin Coulombe-Huntington, Elizabeth Dann, Matija Dreze, Amélie Dricot, Changyu Fan, Eric Franzosa, Fana Gebreab, Bryan J. Gutierrez, Madeleine F. Hardy, Mike Jin, Shuli Kang, Ruth Kiros, Guan Ning Lin, Katja Luck, Andrew MacWilliams, Jörg Menche, Ryan R. Murray, Alexandre Palagi, Matthew M. Poulin, Xavier Rambout, John Rasla, Patrick Reichert, Viviana Romero, Elien Ruyssinck, Julie M. Sahalie, Annemarie Scholz, Akash A. Shah, Amitabh Sharma, Yun Shen, Kerstin Spirohn, Stanley Tam, Alexander O. Tejeda, Shelly A. Wanamaker, Jean-Claude Twizere, Kerwin Vega, Jennifer Walsh, Michael E. Cusick, Yu Xia, Albert-László Barabási, Lilia M. Iakoucheva, Patrick Aloy, Javier De Las Rivas, Jan Tavernier, Michael A. Calderwood, David E. Hill, Tong Hao, Frederick P. Roth, Marc Vidal

Cell. Author manuscript; available in PMC 2015 Nov 20.

Published in final edited form as: Cell. 2014 Nov 20; 159(5): 1212–1226. doi: 10.1016/j.cell.2014.10.050

PMCID:: PMC4266588

Abstract Article PDF–3.1M

Select item 317805913.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 316024514.

Modulation of Tcf3 repressor complex composition regulates cdx4 expression in zebrafish

Hyunju Ro, Igor B Dawid

EMBO J. 2011 Jul 20; 30(14): 2894–2907. Published online 2011 Jun 10. doi: 10.1038/emboj.2011.184

PMCID:: PMC3160245

Abstract Article PDF–1.2M

Select item 313536115.

E4F1 deficiency results in oxidative stress–mediated cell death of leukemic cells

Elodie Hatchi, Genevieve Rodier, Matthieu Lacroix, Julie Caramel, Olivier Kirsh, Chantal Jacquet, Emilie Schrepfer, Sylviane Lagarrigue, Laetitia Karine Linares, Gwendaline Lledo, Sylvie Tondeur, Pierre Dubus, Claude Sardet, Laurent Le Cam

J Exp Med. 2011 Jul 4; 208(7): 1403–1417. doi: 10.1084/jem.20101995

PMCID:: PMC3135361

Abstract Article PDF–3.7M

Select item 190589316.

The role of LANP and ataxin 1 in E4F-mediated transcriptional repression

Marija Cvetanovic, Robert J Rooney, Jesus J Garcia, Nataliya Toporovskaya, Huda Y Zoghbi, Puneet Opal

EMBO Rep. 2007 Jul; 8(7): 671–677. Published online 2007 Jun 8. doi: 10.1038/sj.embor.7400983

PMCID:: PMC1905893

Abstract Article PDF–251K

Select item 161870517.

E4F1, a Novel Estrogen-Responsive Gene in Possible Atheroprotection, Revealed by Microarray Analysis

Yasuhiro Nakamura, Katsuhide Igarashi, Takashi Suzuki, Jun Kanno, Tohru Inoue, Chika Tazawa, Masayuki Saruta, Tomoko Ando, Noriko Moriyama, Toru Furukawa, Masao Ono, Takuya Moriya, Kiyoshi Ito, Haruo Saito, Tadashi Ishibashi, Shoki Takahashi, Shogo Yamada, Hironobu Sasano

Am J Pathol. 2004 Dec; 165(6): 2019–2031. doi: 10.1016/S0002-9440(10)63253-1

PMCID:: PMC1618705

Abstract Article PDF–1.0M

Select item 44214818.

Functional Proteomics Mapping of a Human Signaling Pathway

Frédéric Colland, Xavier Jacq, Virginie Trouplin, Christelle Mougin, Caroline Groizeleau, Alexandre Hamburger, Alain Meil, Jérôme Wojcik, Pierre Legrain, Jean-Michel Gauthier

Genome Res. 2004 Jul; 14(7): 1324–1332. doi: 10.1101/gr.2334104

PMCID:: PMC442148

Abstract Article PDF–290K

Select item 44214719.

A Protein Interaction Framework for Human mRNA Degradation

Ben Lehner, Christopher M. Sanderson

Genome Res. 2004 Jul; 14(7): 1315–1323. doi: 10.1101/gr.2122004

PMCID:: PMC442147

Abstract Article PDF–272K

Select item 36118620.

E4F and ATF, two transcription factors that recognize the same site, can be distinguished both physically and functionally: a role for E4F in E1A trans activation.

R J Rooney, P Raychaudhuri, J R Nevins

Mol Cell Biol. 1990 Oct; 10(10): 5138–5149. doi: 10.1128/mcb.10.10.5138

PMCID:: PMC361186

Summary Page Browse PDF–3.0M

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