PMC Links for GEO Profiles (Select 102082860) - PMC

Select item 98430551.

Karyopherin α deficiency contributes to human preimplantation embryo arrest

Wenjing Wang, Yoichi Miyamoto, Biaobang Chen, Juanzi Shi, Feiyang Diao, Wei Zheng, Qun Li, Lan Yu, Lin Li, Yao Xu, Ling Wu, Xiaoyan Mao, Jing Fu, Bin Li, Zheng Yan, Rong Shi, Xia Xue, Jian Mu, Zhihua Zhang, Tianyu Wu, Lin Zhao, Weijie Wang, Zhou Zhou, Jie Dong, Qiaoli Li, Li Jin, Lin He, Xiaoxi Sun, Ge Lin, Yanping Kuang, Lei Wang, Qing Sang

J Clin Invest. 2023 Jan 17; 133(2): e159951. Published online 2023 Jan 17. doi: 10.1172/JCI159951

PMCID:: PMC9843055

Abstract Article PDF–2.0M

Select item 80177202.

SLFN11 promotes CDT1 degradation by CUL4 in response to replicative DNA damage, while its absence leads to synthetic lethality with ATR/CHK1 inhibitors

Ukhyun Jo, Yasuhisa Murai, Sirisha Chakka, Lu Chen, Ken Cheng, Junko Murai, Liton Kumar Saha, Lisa M. Miller Jenkins, Yves Pommier

Proc Natl Acad Sci U S A. 2021 Feb 9; 118(6): e2015654118. Published online 2021 Feb 3. doi: 10.1073/pnas.2015654118

PMCID:: PMC8017720

Abstract Article PDF–1.9M

Select item 70760153.

An epilepsy-associated mutation in the nuclear import receptor KPNA7 reduces nuclear localization signal binding

Luke T. Oostdyk, Zhenjia Wang, Chongzhi Zang, Hui Li, Michael J. McConnell, Bryce M. Paschal

Sci Rep. 2020; 10: 4844. Published online 2020 Mar 16. doi: 10.1038/s41598-020-61369-5

PMCID:: PMC7076015

Abstract Article PDF–8.6M

Select item 59993964.

The HIV-1 Tat protein recruits a ubiquitin ligase to reorganize the 7SK snRNP for transcriptional activation

Tyler B Faust, Yang Li, Curtis W Bacon, Gwendolyn M Jang, Amit Weiss, Bhargavi Jayaraman, Billy W Newton, Nevan J Krogan, Iván D'Orso, Alan D Frankel

eLife. 2018; 7: e31879. Published online 2018 May 30. doi: 10.7554/eLife.31879

PMCID:: PMC5999396

Abstract Article PDF–3.6M

Select item 58709265.

Depletion of nuclear import protein karyopherin alpha 7 (KPNA7) induces mitotic defects and deformation of nuclei in cancer cells

Elisa M. Vuorinen, Nina K. Rajala, Teemu O. Ihalainen, Anne Kallioniemi

BMC Cancer. 2018; 18: 325. Published online 2018 Mar 27. doi: 10.1186/s12885-018-4261-5

Correction in:: BMC Cancer. 2019; 19: 57.

PMCID:: PMC5870926

Abstract Article PDF–1.7M

Select item 55229646.

Degradation of the Transcription Factor Twist, an Oncoprotein that Promotes Cancer Metastasis

Jiateng Zhong, Kohei Ogura, Zhiwei Wang, Hiroyuki Inuzuka

Discov Med. Author manuscript; available in PMC 2017 Jul 24.

Published in final edited form as: Discov Med. 2013 Jan; 15(80): 7–15.

PMCID:: PMC5522964

Abstract Article PDF–784K

Select item 45050447.

IPO3-mediated Nonclassical Nuclear Import of NF-κB Essential Modulator (NEMO) Drives DNA Damage-dependent NF-κB Activation

Byounghoon Hwang, Kevin McCool, Jun Wan, Shelly M. Wuerzberger-Davis, Edmond W. K. Young, Eun Young Choi, Gino Cingolani, Beth A. Weaver, Shigeki Miyamoto

J Biol Chem. 2015 Jul 17; 290(29): 17967–17984. Published online 2015 Jun 9. doi: 10.1074/jbc.M115.645960

PMCID:: PMC4505044

Abstract Article PDF–4.6M

Select item 39925598.

Autosomal recessive mutations in nuclear transport factor KPNA7 are associated with infantile spasms and cerebellar malformation

Alex R Paciorkowski, Judy Weisenberg, Joshua B Kelley, Adam Spencer, Emily Tuttle, Dalia Ghoneim, Liu Lin Thio, Susan L Christian, William B Dobyns, Bryce M Paschal

Eur J Hum Genet. 2014 May; 22(5): 587–593. Published online 2013 Sep 18. doi: 10.1038/ejhg.2013.196

PMCID:: PMC3992559

Abstract Article PDF–2.1M

Select item 32192039.

Exploring the link between MORF4L1 and risk of breast cancer

Griselda Martrat, Christopher A Maxwell, Emiko Tominaga, Montserrat Porta-de-la-Riva, Núria Bonifaci, Laia Gómez-Baldó, Massimo Bogliolo, Conxi Lázaro, Ignacio Blanco, Joan Brunet, Helena Aguilar, Juana Fernández-Rodríguez, Sheila Seal, Anthony Renwick, Nazneen Rahman, Julia Kühl, Kornelia Neveling, Detlev Schindler, María J Ramírez, María Castellà, Gonzalo Hernández, Douglas F Easton, Susan Peock, Margaret Cook, Clare T Oliver, Debra Frost, Radka Platte, D Gareth Evans, Fiona Lalloo, Rosalind Eeles, Louise Izatt, Carol Chu, Rosemarie Davidson, Kai-Ren Ong, Jackie Cook, Fiona Douglas, Shirley Hodgson, Carole Brewer, Patrick J Morrison, Mary Porteous, Paolo Peterlongo, Siranoush Manoukian, Bernard Peissel, Daniela Zaffaroni, Gaia Roversi, Monica Barile, Alessandra Viel, Barbara Pasini, Laura Ottini, Anna Laura Putignano, Antonella Savarese, Loris Bernard, Paolo Radice, Sue Healey, Amanda Spurdle, Xiaoqing Chen, Jonathan Beesley, Matti A Rookus, Senno Verhoef, Madeleine A Tilanus-Linthorst, Maaike P Vreeswijk, Christi J Asperen, Danielle Bodmer, Margreet GEM Ausems, Theo A van Os, Marinus J Blok, Hanne EJ Meijers-Heijboer, Frans BL Hogervorst, David E Goldgar, Saundra Buys, Esther M John, Alexander Miron, Melissa Southey, Mary B Daly, Katja Harbst, Åke Borg, Johanna Rantala, Gisela Barbany-Bustinza, Hans Ehrencrona, Marie Stenmark-Askmalm, Bella Kaufman, Yael Laitman, Roni Milgrom, Eitan Friedman, Susan M Domchek, Katherine L Nathanson, Timothy R Rebbeck, Oskar Thor Johannsson, Fergus J Couch, Xianshu Wang, Zachary Fredericksen, Daniel Cuadras, Víctor Moreno, Friederike K Pientka, Reinhard Depping, Trinidad Caldés, Ana Osorio, Javier Benítez, Juan Bueren, Tuomas Heikkinen, Heli Nevanlinna, Ute Hamann, Diana Torres, Maria Adelaide Caligo, Andrew K Godwin, Evgeny N Imyanitov, Ramunas Janavicius, Olga M Sinilnikova, Dominique Stoppa-Lyonnet, Sylvie Mazoyer, Carole Verny-Pierre, Laurent Castera, Antoine de Pauw, Yves-Jean Bignon, Nancy Uhrhammer, Jean-Philippe Peyrat, Philippe Vennin, Sandra Fert Ferrer, Marie-Agnès Collonge-Rame, Isabelle Mortemousque, Lesley McGuffog, Georgia Chenevix-Trench, Olivia M Pereira-Smith, Antonis C Antoniou, Julián Cerón, Kaoru Tominaga, Jordi Surrallés, Miguel Angel Pujana

Breast Cancer Res. 2011; 13(2): R40. Published online 2011 Apr 5. doi: 10.1186/bcr2862

PMCID:: PMC3219203

Abstract Article PDF–2.9M

Select item 317805910.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 296416511.

An actin-regulated importin α/β-dependent extended bipartite NLS directs nuclear import of MRTF-A

Rafał Pawłowski, Eeva Kaisa Rajakylä, Maria K Vartiainen, Richard Treisman

EMBO J. 2010 Oct 20; 29(20): 3448–3458. Published online 2010 Sep 3. doi: 10.1038/emboj.2010.216

PMCID:: PMC2964165

Abstract Article PDF–987K

Select item 292922012.

Karyopherin α7 (KPNA7), a divergent member of the importin α family of nuclear import receptors

Joshua B Kelley, Ashley M Talley, Adam Spencer, Daniel Gioeli, Bryce M Paschal

BMC Cell Biol. 2010; 11: 63. Published online 2010 Aug 11. doi: 10.1186/1471-2121-11-63

PMCID:: PMC2929220

Abstract Article PDF–2.8M

Select item 288296113.

Human Chromosome 7: DNA Sequence and Biology

Stephen W. Scherer, Joseph Cheung, Jeffrey R. MacDonald, Lucy R. Osborne, Kazuhiko Nakabayashi, Jo-Anne Herbrick, Andrew R. Carson, Layla Parker-Katiraee, Jennifer Skaug, Razi Khaja, Junjun Zhang, Alexander K. Hudek, Martin Li, May Haddad, Gavin E. Duggan, Bridget A. Fernandez, Emiko Kanematsu, Simone Gentles, Constantine C. Christopoulos, Sanaa Choufani, Dorota Kwasnicka, Xiangqun H. Zheng, Zhongwu Lai, Deborah Nusskern, Qing Zhang, Zhiping Gu, Fu Lu, Susan Zeesman, Malgorzata J. Nowaczyk, Ikuko Teshima, David Chitayat, Cheryl Shuman, Rosanna Weksberg, Elaine H. Zackai, Theresa A. Grebe, Sarah R. Cox, Susan J. Kirkpatrick, Nazneen Rahman, Jan M. Friedman, Henry H. Q. Heng, Pier Giuseppe Pelicci, Francesco Lo-Coco, Elena Belloni, Lisa G. Shaffer, Barbara Pober, Cynthia C. Morton, James F. Gusella, Gail A. P. Bruns, Bruce R. Korf, Bradley J. Quade, Azra H. Ligon, Heather Ferguson, Anne W. Higgins, Natalia T. Leach, Steven R. Herrick, Emmanuelle Lemyre, Chantal G. Farra, Hyung-Goo Kim, Anne M. Summers, Karen W. Gripp, Wendy Roberts, Peter Szatmari, Elizabeth J. T. Winsor, Karl-Heinz Grzeschik, Ahmed Teebi, Berge A. Minassian, Juha Kere, Lluis Armengol, Miguel Angel Pujana, Xavier Estivill, Michael D. Wilson, Ben F. Koop, Sabrina Tosi, Gudrun E. Moore, Andrew P. Boright, Eitan Zlotorynski, Batsheva Kerem, Peter M. Kroisel, Erwin Petek, David G. Oscier, Sarah J. Mould, Hartmut Döhner, Konstanze Döhner, Johanna M. Rommens, John B. Vincent, J. Craig Venter, Peter W. Li, Richard J. Mural, Mark D. Adams, Lap-Chee Tsui

Science. Author manuscript; available in PMC 2010 Jun 9.

Published in final edited form as: Science. 2003 May 2; 300(5620): 767–772. Published online 2003 Apr 10. doi: 10.1126/science.1083423

PMCID:: PMC2882961

Abstract Article PDF–1.2M

Select item 243104114.

Isolation and Characterization of a Novel H1.2 Complex That Acts as a Repressor of p53-mediated Transcription

Kyunghwan Kim, Jongkyu Choi, Kyu Heo, Hyunjung Kim, David Levens, Kimitoshi Kohno, Edward M. Johnson, Hugh W. Brock, Woojin An

J Biol Chem. 2008 Apr 4; 283(14): 9113–9126. doi: 10.1074/jbc.M708205200

PMCID:: PMC2431041

Abstract Article PDF–757K

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