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Items: 1 to 20 of 42

1.
A model for the signal initiation complex between Arrestin-3 and the Src family kinase Fgr
Ivette Perez, Sandra Berndt, Rupesh Agarwal, Manuel A. Castro, Sergey A. Vishnivetskiy, Jeremy C. Smith, Charles R. Sanders, Vsevolod V. Gurevich, T.M. Iverson
J Mol Biol. Author manuscript; available in PMC 2023 Jan 30.
Published in final edited form as: J Mol Biol. 2022 Jan 30; 434(2): 167400. Published online 2021 Dec 11. doi: 10.1016/j.jmb.2021.167400
PMCID:
PMC8752512
AbstractArticlePDF–2.0M
2.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
3.
Kinase Interaction Network Expands Functional and Disease Roles of Human Kinases
Marija Buljan, Rodolfo Ciuffa, Audrey van Drogen, Anton Vichalkovski, Martin Mehnert, George Rosenberger, Sohyon Lee, Markku Varjosalo, Lucia Espona Pernas, Vincent Spegg, Berend Snijder, Ruedi Aebersold, Matthias Gstaiger
Mol Cell. 2020 Aug 6; 79(3): 504–520.e9. doi: 10.1016/j.molcel.2020.07.001
PMCID:
PMC7427327
AbstractArticle
4.
RIG-I regulates myeloid differentiation by promoting TRIM25-mediated ISGylation
Song-Fang Wu, Li Xia, Xiao-Dong Shi, Yu-Jun Dai, Wei-Na Zhang, Jun-Mei Zhao, Wu Zhang, Xiang-Qin Weng, Jing Lu, Huang-Ying Le, Sheng-ce Tao, Jiang Zhu, Zhu Chen, Yue-Ying Wang, Saijuan Chen
Proc Natl Acad Sci U S A. 2020 Jun 23; 117(25): 14395–14404. Published online 2020 Jun 8. doi: 10.1073/pnas.1918596117
PMCID:
PMC7322067
AbstractArticlePDF–2.7M
5.
Extensive rewiring of the EGFR network in colorectal cancer cells expressing transforming levels of KRASG13D
Susan A. Kennedy, Mohamed-Ali Jarboui, Sriganesh Srihari, Cinzia Raso, Kenneth Bryan, Layal Dernayka, Theodosia Charitou, Manuel Bernal-Llinares, Carlos Herrera-Montavez, Aleksandar Krstic, David Matallanas, Max Kotlyar, Igor Jurisica, Jasna Curak, Victoria Wong, Igor Stagljar, Thierry LeBihan, Lisa Imrie, Priyanka Pillai, Miriam A. Lynn, Erik Fasterius, Cristina Al-Khalili Szigyarto, James Breen, Christina Kiel, Luis Serrano, Nora Rauch, Oleksii Rukhlenko, Boris N. Kholodenko, Luis F. Iglesias-Martinez, Colm J. Ryan, Ruth Pilkington, Patrizia Cammareri, Owen Sansom, Steven Shave, Manfred Auer, Nicola Horn, Franziska Klose, Marius Ueffing, Karsten Boldt, David J. Lynn, Walter Kolch
Nat Commun. 2020; 11: 499. Published online 2020 Jan 24. doi: 10.1038/s41467-019-14224-9
PMCID:
PMC6981206
AbstractArticlePDF–3.7M
6.
Expression of myeloid Src-family kinases is associated with poor prognosis in AML and influences Flt3-ITD kinase inhibitor acquired resistance
Ravi K. Patel, Mark C. Weir, Kexin Shen, Daniel Snyder, Vaughn S. Cooper, Thomas E. Smithgall
PLoS One. 2019; 14(12): e0225887. Published online 2019 Dec 2. doi: 10.1371/journal.pone.0225887
PMCID:
PMC6886798
AbstractArticlePDF–3.8M
7.
The midbody interactome reveals unexpected roles for PP1 phosphatases in cytokinesis
Luisa Capalbo, Zuni I. Bassi, Marco Geymonat, Sofia Todesca, Liviu Copoiu, Anton J. Enright, Giuliano Callaini, Maria Giovanna Riparbelli, Lu Yu, Jyoti S. Choudhary, Enrico Ferrero, Sally Wheatley, Max E. Douglas, Masanori Mishima, Pier Paolo D’Avino
Nat Commun. 2019; 10: 4513. Published online 2019 Oct 4. doi: 10.1038/s41467-019-12507-9
PMCID:
PMC6778137
AbstractArticlePDF–7.8M
8.
Selective inhibition of the myeloid Src-family kinase Fgr potently suppresses AML cell growth in vitro and in vivo
Mark C. Weir, Sherry T. Shu, Ravi K. Patel, Sabine Hellwig, Li Chen, Li Tan, Nathanael S. Gray, Thomas E. Smithgall
ACS Chem Biol. Author manuscript; available in PMC 2018 Sep 10.
Published in final edited form as: ACS Chem Biol. 2018 Jun 15; 13(6): 1551–1559. Published online 2018 May 30. doi: 10.1021/acschembio.8b00154
PMCID:
PMC6130198
AbstractArticlePDF–1.7M
9.
The HIV-1 Tat protein recruits a ubiquitin ligase to reorganize the 7SK snRNP for transcriptional activation
Tyler B Faust, Yang Li, Curtis W Bacon, Gwendolyn M Jang, Amit Weiss, Bhargavi Jayaraman, Billy W Newton, Nevan J Krogan, Iván D'Orso, Alan D Frankel
eLife. 2018; 7: e31879. Published online 2018 May 30. doi: 10.7554/eLife.31879
PMCID:
PMC5999396
AbstractArticlePDF–3.6M
10.
The SRC-family tyrosine kinase HCK shapes the landscape of SKAP2 interactome
Jean-François Bureau, Patricia Cassonnet, Laura Grange, Julien Dessapt, Louis Jones, Caroline Demeret, Anavaj Sakuntabhai, Yves Jacob
Oncotarget. 2018 Mar 2; 9(17): 13102–13115. Published online 2018 Feb 6. doi: 10.18632/oncotarget.24424
PMCID:
PMC5862564
AbstractArticlePDF–2.2M
11.
Architecture of the human interactome defines protein communities and disease networks
Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper
Nature. Author manuscript; available in PMC 2017 Nov 17.
Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366
PMCID:
PMC5531611
AbstractArticlePDF–2.7M
12.
A novel approach to detect resistance mechanisms reveals FGR as a factor mediating HDAC inhibitor SAHA resistance in B‐cell lymphoma
Maria Joosten, Sebastian Ginzel, Christian Blex, Dmitri Schmidt, Michael Gombert, Cai Chen, René Martin Linka, Olivia Gräbner, Anika Hain, Burkhard Hirsch, Anke Sommerfeld, Anke Seegebarth, Uschi Gruber, Corinna Maneck, Langhui Zhang, Katharina Stenin, Henrik Dieks, Michael Sefkow, Carsten Münk, Claudia D. Baldus, Ralf Thiele, Arndt Borkhardt, Michael Hummel, Hubert Köster, Ute Fischer, Mathias Dreger, Volkhard Seitz
Mol Oncol. 2016 Oct; 10(8): 1232–1244. Published online 2016 Jun 9. doi: 10.1016/j.molonc.2016.06.001
PMCID:
PMC5423193
AbstractArticlePDF–1.3M
13.
The Src and c-Kit kinase inhibitor dasatinib enhances p53-mediated targeting of human acute myeloid leukemia stem cells by chemotherapeutic agents
Cedric Dos Santos, Tinisha McDonald, Yin Wei Ho, Hongjun Liu, Allen Lin, Stephen J. Forman, Ya-Huei Kuo, Ravi Bhatia
Blood. 2013 Sep 12; 122(11): 1900–1913. Prepublished online 2013 Jul 29. doi: 10.1182/blood-2012-11-466425
PMCID:
PMC4968345
AbstractArticle
14.
The BioPlex Network: A Systematic Exploration of the Human Interactome
Edward L. Huttlin, Lily Ting, Raphael J. Bruckner, Fana Gebreab, Melanie P. Gygi, John Szpyt, Stanley Tam, Gabriela Zarraga, Greg Colby, Kurt Baltier, Rui Dong, Virginia Guarani, Laura Pontano Vaites, Alban Ordureau, Ramin Rad, Brian K. Erickson, Martin Wühr, Joel Chick, Bo Zhai, Deepak Kolippakkam, Julian Mintseris, Robert A. Obar, Tim Harris, Spyros Artavanis-Tsakonas, Mathew E. Sowa, Pietro DeCamilli, Joao A. Paulo, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2016 Jul 16.
Published in final edited form as: Cell. 2015 Jul 16; 162(2): 425–440. doi: 10.1016/j.cell.2015.06.043
PMCID:
PMC4617211
AbstractArticlePDF–2.2M
15.
Involvement of the HCK and FGR src-Family Kinases in FCRL4-Mediated Immune Regulation
Yanling Liu, Ksenia Bezverbnaya, Tiantian Zhao, Marion J. Parsons, Mengyao Shi, Bebhinn Treanor, Götz R. A. Ehrhardt
J Immunol. 2015 Jun 15; 194(12): 5851–5860. Published online 2015 May 13. doi: 10.4049/jimmunol.1401533
PMCID:
PMC4456631
AbstractArticlePDF–1.4M
16.
Enhanced Prediction of Src Homology 2 (SH2) Domain Binding Potentials Using a Fluorescence Polarization-derived c-Met, c-Kit, ErbB, and Androgen Receptor Interactome
Kin K. Leung, Ronald J. Hause, Jr., John L. Barkinge, Mark F. Ciaccio, Chih-Pin Chuu, Richard B. Jones
Mol Cell Proteomics. 2014 Jul; 13(7): 1705–1723. Published online 2014 Apr 12. doi: 10.1074/mcp.M113.034876
PMCID:
PMC4083110
AbstractArticlePDF–6.6M
17.
Quantitative Analysis of Hsp90-Client Interactions Reveals Principles of Substrate Recognition
Mikko Taipale, Irina Krykbaeva, Martina Koeva, Can Kayatekin, Kenneth D. Westover, Georgios I. Karras, Susan Lindquist
Cell. Author manuscript; available in PMC 2014 Jan 17.
Published in final edited form as: Cell. 2012 Aug 31; 150(5): 987–1001. doi: 10.1016/j.cell.2012.06.047
PMCID:
PMC3894786
AbstractArticlePDF–5.0M
18.
HIV-1 gp120 impairs B cell proliferation by inducing TGF-ß1 production and FcRL4 expression
Katija Jelicic, Raffaello Cimbro, Fatima Nawaz, Da Wei Huang, Xin Zheng, Jun Yang, Richard A. Lempicki, Massimiliano Pascuccio, Donald Van Ryk, Catherine Schwing, Joseph Hiatt, Noreen Okwara, Danlan Wei, Gregg Roby, Antonio David, Young Hwang, II, John H. Kehrl, James Arthos, Claudia Cicala, Anthony S. Fauci
Nat Immunol. Author manuscript; available in PMC 2014 Jun 1.
Published in final edited form as: Nat Immunol. 2013 Dec; 14(12): 1256–1265. Published online 2013 Oct 27. doi: 10.1038/ni.2746
PMCID:
PMC3870659
AbstractArticlePDF–1.4M
19.
SRC Homology 2 Domain Binding Sites in Insulin, IGF-1 and FGF receptor mediated signaling networks reveal an extensive potential interactome
Bernard A Liu, Brett W Engelmann, Karl Jablonowski, Katherine Higginbotham, Andrew B Stergachis, Piers D Nash
Cell Commun Signal. 2012; 10: 27. Published online 2012 Sep 14. doi: 10.1186/1478-811X-10-27
PMCID:
PMC3514216
AbstractArticlePDF–2.4M
20.
Novel Phosphorylations of IKKγ/NEMO
Sun Hwa Lee, Zsolt Toth, Lai-Yee Wong, Kevin Brulois, Jim Nguyen, June-Yong Lee, Ebrahim Zandi, Jae U. Jung
mBio. 2012 Nov-Dec; 3(6): e00411-12. Published online 2012 Nov 6. doi: 10.1128/mBio.00411-12
PMCID:
PMC3487776
AbstractArticlePDF–1.3M

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