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Select item 105794721.

Biallelic NPR1 loss of function variants are responsible for neonatal systemic hypertension

Yline Capri, Theresa Kwon, Olivia Boyer, Lucas Bourmance, Noe Testa, Véronique Baudouin, Ronan Bonnefoy, Anne Couderc, Chakib Meziane, Elisabeth Tournier-Lasserve, Laurence Heidet, Judith Melki

J Med Genet. 2023 Oct; 60(10): 993–998. Published online 2023 Apr 20. doi: 10.1136/jmg-2023-109176

PMCID:: PMC10579472

Abstract Article PDF–696K

Select item 94142222.

The pseudokinase domains of guanylyl cyclase–A and –B allosterically increase the affinity of their catalytic domains for substrate

Aaron B. Edmund, Timothy F. Walseth, Nicholas M. Levinson, Lincoln R. Potter

Sci Signal. Author manuscript; available in PMC 2022 Aug 26.

Published in final edited form as: Sci Signal. 2019 Jan 29; 12(566): eaau5378. Published online 2019 Jan 29. doi: 10.1126/scisignal.aau5378

PMCID:: PMC9414222

Abstract Article PDF–4.0M

Select item 92316233.

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1

Boris Simonetti, James L. Daly, Lorena Simón-Gracia, Katja Klein, Saroja Weeratunga, Carlos Antón-Plágaro, Allan Tobi, Lorna Hodgson, Philip A. Lewis, Kate J. Heesom, Deborah K. Shoemark, Andrew D. Davidson, Brett M. Collins, Tambet Teesalu, Yohei Yamauchi, Peter J. Cullen

Proc Natl Acad Sci U S A. 2022 Jun 21; 119(25): e2201980119. Published online 2022 Jun 13. doi: 10.1073/pnas.2201980119

PMCID:: PMC9231623

Abstract Article PDF–6.0M

Select item 87198544.

Discovery of small molecule guanylyl cyclase A receptor positive allosteric modulators

S. Jeson Sangaralingham, Kanupriya Whig, Satyamaheshwar Peddibhotla, R. Jason Kirby, Hampton E. Sessions, Patrick R. Maloney, Paul M. Hershberger, Heather Mose-Yates, Becky L. Hood, Stefan Vasile, Shuchong Pan, Ye Zheng, Siobhan Malany, John C. Burnett, Jr.

Proc Natl Acad Sci U S A. 2021 Dec 28; 118(52): e2109386118. Published online 2021 Dec 20. doi: 10.1073/pnas.2109386118

PMCID:: PMC8719854

Abstract Article PDF–1.5M

Select item 85288245.

Natriuretic peptide receptor a promotes gastric malignancy through angiogenesis process

Zheng Li, Hao Fan, Jiacheng Cao, Guangli Sun, Sen Wang, Jialun Lv, Zhe Xuan, Yiwen Xia, Linjun Wang, Diancai Zhang, Hao Xu, Zekuan Xu

Cell Death Dis. 2021 Nov; 12(11): 968. Published online 2021 Oct 20. doi: 10.1038/s41419-021-04266-7

PMCID:: PMC8528824

Abstract Article PDF–5.2M

Select item 77927876.

ANP and BNP Exert Anti-Inflammatory Action via NPR-1/cGMP Axis by Interfering with Canonical, Non-Canonical, and Alternative Routes of Inflammasome Activation in Human THP1 Cells

Letizia Mezzasoma, Vincenzo Nicola Talesa, Rita Romani, Ilaria Bellezza

Int J Mol Sci. 2021 Jan; 22(1): 24. Published online 2020 Dec 22. doi: 10.3390/ijms22010024

PMCID:: PMC7792787

Abstract Article PDF–3.6M

Select item 62931157.

Molecular and genetic aspects of guanylyl cyclase natriuretic peptide receptor-A in regulation of blood pressure and renal function

Kailash N. Pandey

Physiol Genomics. 2018 Nov 1; 50(11): 913–928. Published online 2018 Aug 31. doi: 10.1152/physiolgenomics.00083.2018

PMCID:: PMC6293115

Abstract Article

Select item 55572928.

Synergistic drug combinations for cancer identified in a CRISPR screen for pairwise genetic interactions

Kyuho Han, Edwin E. Jeng, Gaelen T. Hess, David W. Morgens, Amy Li, Michael C. Bassik

Nat Biotechnol. Author manuscript; available in PMC 2017 Sep 20.

Published in final edited form as: Nat Biotechnol. 2017 May; 35(5): 463–474. Published online 2017 Mar 20. doi: 10.1038/nbt.3834

PMCID:: PMC5557292

Abstract Article PDF–3.4M

Select item 55208559.

Ubiquitylation of p62/sequestosome1 activates its autophagy receptor function and controls selective autophagy upon ubiquitin stress

Hong Peng, Jiao Yang, Guangyi Li, Qing You, Wen Han, Tianrang Li, Daming Gao, Xiaoduo Xie, Byung-Hoon Lee, Juan Du, Jian Hou, Tao Zhang, Hai Rao, Ying Huang, Qinrun Li, Rong Zeng, Lijian Hui, Hongyan Wang, Qin Xia, Xuemin Zhang, Yongning He, Masaaki Komatsu, Ivan Dikic, Daniel Finley, Ronggui Hu

Cell Res. 2017 May; 27(5): 657–674. Published online 2017 Mar 21. doi: 10.1038/cr.2017.40

PMCID:: PMC5520855

Abstract Article PDF–7.2M

Select item 462686910.

Subcellular trafficking of guanylyl cyclase/natriuretic peptide receptor-A with concurrent generation of intracellular cGMP

Indra Mani, Renu Garg, Satyabha Tripathi, Kailash N. Pandey

Biosci Rep. 2015 Oct; 35(5): e00260. Prepublished online 2015 Sep 15. Published online 2015 Oct 30. doi: 10.1042/BSR20150136

PMCID:: PMC4626869

Abstract Article PDF–1.9M

Select item 449588711.

MASS SPECTROMETRIC IDENTIFICATION OF PHOSPHORYLATION SITES IN GUANYLYL CYCLASE A AND B

Andrea R. Yoder, Matthew D. Stone, Timothy J. Griffin, Lincoln R. Potter

Biochemistry. Author manuscript; available in PMC 2015 Jul 8.

Published in final edited form as: Biochemistry. 2010 Nov 30; 49(47): 10137–10145. Published online 2010 Nov 8. doi: 10.1021/bi101700e

PMCID:: PMC4495887

Abstract Article PDF–1.8M

Select item 441139812.

Guanylyl Cyclases A and B Are Asymmetric Dimers That Are Allosterically Activated by ATP Binding to the Catalytic Domain

Jerid W. Robinson, Lincoln R. Potter

Sci Signal. Author manuscript; available in PMC 2015 Apr 28.

Published in final edited form as: Sci Signal. 2012 Sep 4; 5(240): ra65. Published online 2012 Sep 4. doi: 10.1126/scisignal.2003253

PMCID:: PMC4411398

Abstract Article PDF–1.7M

Select item 432188813.

Common variations in noncoding regions of the human natriuretic peptide receptor A gene have quantitative effects

Joshua W. Knowles, Laurie M. Erickson, Vanessa K. Guy, Carlie S. Sigel, Jennifer C. Wilder, Nobuyo Maeda

Hum Genet. Author manuscript; available in PMC 2015 Feb 9.

Published in final edited form as: Hum Genet. 2003 Jan; 112(1): 62–70. Published online 2002 Oct 10. doi: 10.1007/s00439-002-0834-z

PMCID:: PMC4321888

Abstract Article PDF–531K

Select item 415795514.

Cardiac Fibrosis in End-Stage Human Heart Failure and the Cardiac Natriuretic Peptide Guanylyl Cyclase System: Regulation and Therapeutic Implications

Tomoko Ichiki, John A Schirger, Brenda K Huntley, Frank C Brozovich, Josef J Maleszewski, Sharon M Sandberg, S Jeson Sangaralingham, Soon J Park, John C Burnett, Jr

J Mol Cell Cardiol. Author manuscript; available in PMC 2015 Oct 1.

Published in final edited form as: J Mol Cell Cardiol. 2014 Oct; 75: 199–205. Published online 2014 Aug 9. doi: 10.1016/j.yjmcc.2014.08.001

PMCID:: PMC4157955

Abstract Article PDF–891K

Select item 406704215.

Guanylyl cyclase (GC)-A and GC-B activities in ventricles and cardiomyocytes from failed and non-failed human hearts: GC-A is inactive in the failed cardiomyocyte

Deborah M. Dickey, Daniel L. Dries, Kenneth B. Margulies, Lincoln R. Potter

J Mol Cell Cardiol. Author manuscript; available in PMC 2014 Jun 23.

Published in final edited form as: J Mol Cell Cardiol. 2012 Mar; 52(3): 727–732. Published online 2011 Nov 22. doi: 10.1016/j.yjmcc.2011.11.007

PMCID:: PMC4067042

Abstract Article PDF–392K

Select item 403837016.

Expression of natriuretic peptide receptor-A in esophageal squamous cell carcinomas and the relationship with tumor invasion and migration

Zhilong Zhao, Haoqian Liu, Ya Yang, Kai Sun, Min Li, Jia Zhang, Hui Cai, Jiansheng Wang

World J Surg Oncol. 2014; 12: 154. Published online 2014 May 21. doi: 10.1186/1477-7819-12-154

PMCID:: PMC4038370

Abstract Article PDF–1.7M

Select item 360488917.

Identification of Fetal and Maternal Single Nucleotide Polymorphisms in Candidate Genes That Predispose to Spontaneous Preterm Labor with Intact Membranes

Roberto Romero, Digna R. Velez, Juan Pedro Kusanovic, Sonia S. Hassan, Shali Mazaki-Tovi, Edi Vaisbuch, Chong Jai Kim, Tinnakorn Chaiworapongsa, Brad Pearce, Lara A. Friel, Jacquelaine Bartlett, Madan Kumar Anant, Benjamin A. Salisbury, Gerald F. Vovis, Min Seob Lee, Ricardo Gomez, Ernesto Behnke, Enrique Oyarzun, Gerard Tromp, Scott M. Williams, Ramkumar Menon

Am J Obstet Gynecol. Author manuscript; available in PMC 2013 Mar 21.

Published in final edited form as: Am J Obstet Gynecol. 2010 May; 202(5): 431.e1–431.34. doi: 10.1016/j.ajog.2010.03.026

PMCID:: PMC3604889

Abstract Article PDF–4.4M

Select item 358195418.

Structural basis for endosomal trafficking of diverse transmembrane cargos by PX-FERM proteins

Rajesh Ghai, Andrea Bugarcic, Huadong Liu, Suzanne J. Norwood, Sune Skeldal, Elizabeth J. Coulson, Shawn Shun-Cheng Li, Rohan D. Teasdale, Brett M. Collins

Proc Natl Acad Sci U S A. 2013 Feb 19; 110(8): E643–E652. Published online 2013 Feb 4. doi: 10.1073/pnas.1216229110

PMCID:: PMC3581954

Abstract Article PDF–2.3M

Select item 328162819.

Cytoplasmic Metadherin (MTDH) Provides Survival Advantage under Conditions of Stress by Acting as RNA-binding Protein

Xiangbing Meng, Danlin Zhu, Shujie Yang, Xinjun Wang, Zhi Xiong, Yuping Zhang, Pavla Brachova, Kimberly K. Leslie

J Biol Chem. 2012 Feb 10; 287(7): 4485–4491. Published online 2011 Dec 23. doi: 10.1074/jbc.C111.291518

PMCID:: PMC3281628

Abstract Article PDF–2.0M

Select item 327854920.

Opposite effects of ANP receptors in attenuation of LPS-induced endothelial permeability and lung injury

Junjie Xing, Bakhtiyor Yakubov, Valeriy Poroyko, Anna A. Birukova

Microvasc Res. Author manuscript; available in PMC 2013 Mar 1.

Published in final edited form as: Microvasc Res. 2012 Mar; 83(2): 194–199. Published online 2011 Oct 6. doi: 10.1016/j.mvr.2011.09.012

PMCID:: PMC3278549

Abstract Article PDF–2.0M

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