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Select item 109385221.

Bone Phenotype is Always Present But Androgen Excess is Less Frequently Seen in PAPSS2 Deficiency

Didem Helvacıoğlu, Tülay Güran

J Clin Res Pediatr Endocrinol. 2024 Mar; 16(1): 4–10. Published online 2024 Mar 11. doi: 10.4274/jcrpe.galenos.2023.2023-12-10

PMCID:: PMC10938522

Abstract Article PDF–500K

Select item 94754532.

The N⁶-methyladenosine-mediated lncRNA WEE2-AS1 promotes glioblastoma progression by stabilizing RPN2

Boyan Li, Rongrong Zhao, Wei Qiu, Ziwen Pan, Shulin Zhao, Yanhua Qi, Jiawei Qiu, Shouji Zhang, Qindong Guo, Yang Fan, Hao Xu, Ming Li, Gang Li, Hao Xue

Theranostics. 2022; 12(14): 6363–6379. Published online 2022 Aug 29. doi: 10.7150/thno.74600

PMCID:: PMC9475453

Abstract Article PDF–4.4M

Select item 92792853.

Scalable multiplex co-fractionation/mass spectrometry platform for accelerated protein interactome discovery

Pierre C. Havugimana, Raghuveera Kumar Goel, Sadhna Phanse, Ahmed Youssef, Dzmitry Padhorny, Sergei Kotelnikov, Dima Kozakov, Andrew Emili

Nat Commun. 2022; 13: 4043. Published online 2022 Jul 13. doi: 10.1038/s41467-022-31809-z

PMCID:: PMC9279285

Abstract Article PDF–2.5M

Select item 91197364.

OpenCell: proteome-scale endogenous tagging enables the cartography of human cellular organization

Nathan H. Cho, Keith C. Cheveralls, Andreas-David Brunner, Kibeom Kim, André C. Michaelis, Preethi Raghavan, Hirofumi Kobayashi, Laura Savy, Jason Y. Li, Hera Canaj, James Y.S. Kim, Edna M. Stewart, Christian Gnann, Frank McCarthy, Joana P. Cabrera, Rachel M. Brunetti, Bryant B. Chhun, Greg Dingle, Marco Y. Hein, Bo Huang, Shalin B. Mehta, Jonathan S. Weissman, Rafael Gómez-Sjöberg, Daniel N. Itzhak, Loic A. Royer, Matthias Mann, Manuel D. Leonetti

Science. Author manuscript; available in PMC 2022 Sep 11.

Published in final edited form as: Science. 2022 Mar 11; 375(6585): eabi6983. Published online 2022 Mar 11. doi: 10.1126/science.abi6983

PMCID:: PMC9119736

Abstract Article PDF–3.3M

Select item 90588365.

The involvement of Parkin-dependent mitophagy in the anti-cancer activity of Ginsenoside

Xin Sun, Yeting Hong, Yuhan Shu, Caixia Wu, Guiqin Ye, Hanxiao Chen, Hongying Zhou, Ruilan Gao, Jianbin Zhang

J Ginseng Res. 2022 Mar; 46(2): 266–274. Published online 2021 Jul 8. doi: 10.1016/j.jgr.2021.06.009

PMCID:: PMC9058836

Abstract Article PDF–2.9M

Select item 90346846.

Identification of variants in ACAN and PAPSS2 leading to spondyloepi(meta)physeal dysplasias in four Chinese families

Yixuan Cao, Xin Guan, Shan Li, Nan Wu, Xiumin Chen, Tao Yang, Bo Yang, Xiuli Zhao

Mol Genet Genomic Med. 2022 May; 10(5): e1916. Published online 2022 Mar 9. doi: 10.1002/mgg3.1916

PMCID:: PMC9034684

Abstract Article PDF–8.1M

Select item 88970227.

Histone deacetylase inhibitors inhibit cervical cancer growth through Parkin acetylation-mediated mitophagy

Xin Sun, Yuhan Shu, Guiqin Ye, Caixia Wu, Mengting Xu, Ruilan Gao, Dongsheng Huang, Jianbin Zhang

Acta Pharm Sin B. 2022 Feb; 12(2): 838–852. Published online 2021 Jul 21. doi: 10.1016/j.apsb.2021.07.003

PMCID:: PMC8897022

Abstract Article PDF–3.0M

Select item 87600778.

The ubiquitin-dependent ATPase p97 removes cytotoxic trapped PARP1 from chromatin

Dragomir B. Krastev, Shudong Li, Yilun Sun, Andrew J. Wicks, Gwendoline Hoslett, Daniel Weekes, Luned M. Badder, Eleanor G. Knight, Rebecca Marlow, Mercedes Calvo Pardo, Lu Yu, Tanaji T. Talele, Jiri Bartek, Jyoti S. Choudhary, Yves Pommier, Stephen J. Pettitt, Andrew N. J. Tutt, Kristijan Ramadan, Christopher J. Lord

Nat Cell Biol. 2022; 24(1): 62–73. Published online 2022 Jan 10. doi: 10.1038/s41556-021-00807-6

PMCID:: PMC8760077

Abstract Article PDF–12M

Select item 82547599.

HectD1 Controls Hematopoietic Stem Cell Regeneration by Coordinating Ribosome Assembly and Protein Synthesis

Kaosheng Lv, Chujie Gong, Charles Antony, Xu Han, Jian-Gang Ren, Ryan Donaghy, Ying Cheng, Simone Pellegrino, Alan J. Warren, Vikram R. Paralkar, Wei Tong

Cell Stem Cell. Author manuscript; available in PMC 2022 Jul 1.

Published in final edited form as: Cell Stem Cell. 2021 Jul 1; 28(7): 1275–1290.e9. Published online 2021 Mar 11. doi: 10.1016/j.stem.2021.02.008

PMCID:: PMC8254759

Abstract Article PDF–2.8M

Select item 823884410.

Intestinal Sulfation is Essential to Protect Against Colitis and Colonic Carcinogenesis

Pengfei Xu, Yue Xi, Junjie Zhu, Min Zhang, Zigmund Luka, Donna B. Stolz, Xinran Cai, Yang Xie, Meishu Xu, Songrong Ren, Zhiying Huang, Da Yang, John D. York, Xiaochao Ma, Wen Xie

Gastroenterology. Author manuscript; available in PMC 2022 Jul 1.

Published in final edited form as: Gastroenterology. 2021 Jul; 161(1): 271–286.e11. Published online 2021 Apr 2. doi: 10.1053/j.gastro.2021.03.048

PMCID:: PMC8238844

Abstract Article PDF–4.2M

Select item 816503011.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 792741512.

FBW7 suppresses ovarian cancer development by targeting the N⁶-methyladenosine binding protein YTHDF2

Fei Xu, Jiajia Li, Mengdong Ni, Jingyi Cheng, Haiyun Zhao, Shanshan Wang, Xiang Zhou, Xiaohua Wu

Mol Cancer. 2021; 20: 45. Published online 2021 Mar 3. doi: 10.1186/s12943-021-01340-8

PMCID:: PMC7927415

Abstract Article PDF–2.9M

Select item 756688113.

Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism

Michael Aregger, Keith A. Lawson, Maximillian Billmann, Michael Costanzo, Amy H. Y. Tong, Katherine Chan, Mahfuzur Rahman, Kevin R. Brown, Catherine Ross, Matej Usaj, Lucy Nedyalkova, Olga Sizova, Andrea Habsid, Judy Pawling, Zhen-Yuan Lin, Hala Abdouni, Cassandra J. Wong, Alexander Weiss, Patricia Mero, James W. Dennis, Anne-Claude Gingras, Chad L. Myers, Brenda J. Andrews, Charles Boone, Jason Moffat

Nat Metab. Author manuscript; available in PMC 2020 Dec 1.

Published in final edited form as: Nat Metab. 2020 Jun; 2(6): 499–513. Published online 2020 Jun 1. doi: 10.1038/s42255-020-0211-z

PMCID:: PMC7566881

Abstract Article PDF–4.8M

Select item 752370614.

Loss of ER retention motif of AGR2 can impact mTORC signaling and promote cancer metastasis

Katrin Tiemann, Carolina Garri, Sang Bok Lee, Paymaneh D. Malihi, Mincheol Park, Ruth M. Alvarez, Li Peng Yap, Parag Mallick, Jonathan E. Katz, Mitchell E. Gross, Kian Kani

Oncogene. Author manuscript; available in PMC 2020 Sep 29.

Published in final edited form as: Oncogene. 2019 Apr; 38(16): 3003–3018. Published online 2018 Dec 21. doi: 10.1038/s41388-018-0638-9

PMCID:: PMC7523706

Abstract Article PDF–2.3M

Select item 737208115.

Unbiased Profiling of the Human Proinsulin Biosynthetic Interaction Network Reveals a Role for Peroxiredoxin 4 in Proinsulin Folding

Duc T. Tran, Anita Pottekat, Saiful A. Mir, Salvatore Loguercio, Insook Jang, Alexandre Rosa Campos, Kathleen M. Scully, Reyhaneh Lahmy, Ming Liu, Peter Arvan, William E. Balch, Randal J. Kaufman, Pamela Itkin-Ansari

Diabetes. 2020 Aug; 69(8): 1723–1734. Published online 2020 May 26. doi: 10.2337/db20-0245

PMCID:: PMC7372081

Abstract Article PDF–2.0M

Select item 716998316.

A reference map of the human binary protein interactome

Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood

Nature. Author manuscript; available in PMC 2020 Oct 8.

Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x

PMCID:: PMC7169983

Abstract Article PDF–5.4M

Select item 677813717.

The midbody interactome reveals unexpected roles for PP1 phosphatases in cytokinesis

Luisa Capalbo, Zuni I. Bassi, Marco Geymonat, Sofia Todesca, Liviu Copoiu, Anton J. Enright, Giuliano Callaini, Maria Giovanna Riparbelli, Lu Yu, Jyoti S. Choudhary, Enrico Ferrero, Sally Wheatley, Max E. Douglas, Masanori Mishima, Pier Paolo D’Avino

Nat Commun. 2019; 10: 4513. Published online 2019 Oct 4. doi: 10.1038/s41467-019-12507-9

PMCID:: PMC6778137

Abstract Article PDF–7.8M

Select item 637078118.

Enhanced PAPSS2/VCAN sulfation axis is essential for Snail-mediated breast cancer cell migration and metastasis

Yihong Zhang, Xiuqun Zou, Wenli Qian, Xiaoling Weng, Lin Zhang, Liang Zhang, Shuang Wang, Xuan Cao, Li Ma, Gang Wei, Yingjie Wu, Zhaoyuan Hou

Cell Death Differ. 2019 Mar; 26(3): 565–579. Published online 2018 Jun 28. doi: 10.1038/s41418-018-0147-y

PMCID:: PMC6370781

Abstract Article PDF–5.3M

Select item 636858419.

The p300/YY1/miR-500a-5p/HDAC2 signalling axis regulates cell proliferation in human colorectal cancer

Weimei Tang, Weijie Zhou, Li Xiang, Xiaosheng Wu, Pei Zhang, Jing Wang, Guangnan Liu, Wenjing Zhang, Ying Peng, Xiaoting Huang, Jianqun Cai, Yang Bai, Lan Bai, Wei Zhu, Hongxiang Gu, Jing Xiong, Chen Ye, Aimin Li, Side Liu, Jide Wang

Nat Commun. 2019; 10: 663. Published online 2019 Feb 8. doi: 10.1038/s41467-018-08225-3

PMCID:: PMC6368584

Abstract Article PDF–6.8M

Select item 628329320.

Discovery of a Human Testis-specific Protein Complex TEX101-DPEP3 and Selection of Its Disrupting Antibodies

Christina Schiza, Dimitrios Korbakis, Efstratia Panteleli, Keith Jarvi, Andrei P. Drabovich, Eleftherios P. Diamandis

Mol Cell Proteomics. 2018 Dec; 17(12): 2480–2495. Published online 2018 Aug 10. doi: 10.1074/mcp.RA118.000749

PMCID:: PMC6283293

Abstract Article PDF–1.9M

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