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Select item 112597961.

Galectin-3-Binding Protein Inhibits Extracellular Heparan 6-O-Endosulfatase Sulf-2

Aswini Panigrahi, Julius Benicky, Reem Aljuhani, Pritha Mukherjee, Zora Nováková, Cyril Bařinka, Radoslav Goldman

Mol Cell Proteomics. 2024 Jul; 23(7): 100793. Published online 2024 Jun 1. doi: 10.1016/j.mcpro.2024.100793

PMCID:: PMC11259796

Abstract Article PDF–1.7M

Select item 111056072.

Expression and purification of recombinant extracellular sulfatase HSulf-2 allows deciphering of enzyme sub-domain coordinated role for the binding and 6-O-desulfation of heparan sulfate

Amal Seffouh, Rana El Masri, Olga Makshakova, Evelyne Gout, Zahra el Oula Hassoun, Jean-pierre Andrieu, Hugues Lortat-Jacob, Romain R. Vivès

Cell Mol Life Sci. 2019 May; 76(9): 1807–1819. Published online 2019 Feb 20. doi: 10.1007/s00018-019-03027-2

PMCID:: PMC11105607

Abstract Article PDF–1.2M

Select item 102374223.

TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing

Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan

Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233

PMCID:: PMC10237422

Abstract Article PDF–23M

Select item 95082254.

Extracellular sulfatase-2 is overexpressed in rheumatoid arthritis and mediates the TNF-α-induced inflammatory activation of synovial fibroblasts

Ruby J. Siegel, Anil K. Singh, Paul M. Panipinto, Farheen S. Shaikh, Judy Vinh, Sang U. Han, H. Mark Kenney, Edward M. Schwarz, Cynthia S. Crowson, Sadik A. Khuder, Basil S. Khuder, David A. Fox, Salahuddin Ahmed

Cell Mol Immunol. 2022 Oct; 19(10): 1185–1195. Published online 2022 Sep 7. doi: 10.1038/s41423-022-00913-x

PMCID:: PMC9508225

Abstract Article PDF–2.4M

Select item 94375635.

SMYD3 Impedes Small Cell Lung Cancer Sensitivity to Alkylation Damage through RNF113A Methylation–Phosphorylation Cross-talk

Valentina Lukinović, Simone Hausmann, Gael S. Roth, Clement Oyeniran, Tanveer Ahmad, Ning Tsao, Joshua R. Brickner, Alexandre G. Casanova, Florent Chuffart, Ana Morales Benitez, Jessica Vayr, Rebecca Rodell, Marianne Tardif, Pascal W.T.C. Jansen, Yohann Couté, Michiel Vermeulen, Pierre Hainaut, Pawel K. Mazur, Nima Mosammaparast, Nicolas Reynoird

Cancer Discov. 2022 Sep 2; 12(9): 2158–2179. Published online 2022 Jul 12. doi: 10.1158/2159-8290.CD-21-0205

PMCID:: PMC9437563

Abstract Article PDF–9.5M

Select item 92316236.

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1

Boris Simonetti, James L. Daly, Lorena Simón-Gracia, Katja Klein, Saroja Weeratunga, Carlos Antón-Plágaro, Allan Tobi, Lorna Hodgson, Philip A. Lewis, Kate J. Heesom, Deborah K. Shoemark, Andrew D. Davidson, Brett M. Collins, Tambet Teesalu, Yohei Yamauchi, Peter J. Cullen

Proc Natl Acad Sci U S A. 2022 Jun 21; 119(25): e2201980119. Published online 2022 Jun 13. doi: 10.1073/pnas.2201980119

PMCID:: PMC9231623

Abstract Article PDF–6.0M

Select item 90750077.

SULF2 monoclonal antibody 5D5 suppresses human cholangiocarcinoma xenograft growth via regulation of a SULF2-PDGFRβ-YAP signaling axis

Xin Luo, Nellie A. Campbell, Li He, Daniel R. O’Brien, Mark S. Singer, Hassan Lemjabbar-Alaoui, Keun Soo Ahn, Rory Smoot, Michael S. Torbenson, Steven D. Rosen, Lewis R. Roberts

Hepatology. Author manuscript; available in PMC 2022 Sep 1.

Published in final edited form as: Hepatology. 2021 Sep; 74(3): 1411–1428. Published online 2021 May 24. doi: 10.1002/hep.31817

PMCID:: PMC9075007

Abstract Article PDF–3.1M

Select item 85529078.

SARS‐CoV‐2–host proteome interactions for antiviral drug discovery

Xiaonan Liu, Sini Huuskonen, Tuomo Laitinen, Taras Redchuk, Mariia Bogacheva, Kari Salokas, Ina Pöhner, Tiina Öhman, Arun Kumar Tonduru, Antti Hassinen, Lisa Gawriyski, Salla Keskitalo, Maria K Vartiainen, Vilja Pietiäinen, Antti Poso, Markku Varjosalo

Mol Syst Biol. 2021 Nov; 17(11): e10396. Published online 2021 Oct 28. doi: 10.15252/msb.202110396

PMCID:: PMC8552907

Abstract Article PDF–3.9M

Select item 81650309.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 739249110.

TGFβ attenuates cartilage extracellular matrix degradation via enhancing FBXO6-mediated MMP14 ubiquitination

Gangliang Wang, Shuai Chen, Ziang Xie, Shuying Shen, Wenbin Xu, Wenxiang Chen, Xiang Li, Yizheng Wu, Liangping Li, Bin Liu, Xianjun Ding, An Qin, Shunwu Fan

Ann Rheum Dis. 2020 Aug; 79(8): 1111–1120. Published online 2020 May 14. doi: 10.1136/annrheumdis-2019-216911

PMCID:: PMC7392491

Abstract Article PDF–14M

Select item 694204411.

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity

Jae Jin Kim, Seo Yun Lee, Fade Gong, Anna M. Battenhouse, Daniel R. Boutz, Aarti Bashyal, Samantha T. Refvik, Cheng-Ming Chiang, Blerta Xhemalce, Tanya T. Paull, Jennifer S. Brodbelt, Edward M. Marcotte, Kyle M. Miller

Genes Dev. 2019 Dec 1; 33(23-24): 1751–1774. doi: 10.1101/gad.331231.119

PMCID:: PMC6942044

Abstract Article PDF–10M

Select item 646824612.

TRF2 positively regulates SULF2 expression increasing VEGF-A release and activity in tumor microenvironment

Pasquale Zizza, Roberto Dinami, Manuela Porru, Chiara Cingolani, Erica Salvati, Angela Rizzo, Carmen D’Angelo, Eleonora Petti, Carla Azzurra Amoreo, Marcella Mottolese, Isabella Sperduti, Angela Chambery, Rosita Russo, Paola Ostano, Giovanna Chiorino, Giovanni Blandino, Andrea Sacconi, Julien Cherfils-Vicini, Carlo Leonetti, Eric Gilson, Annamaria Biroccio

Nucleic Acids Res. 2019 Apr 23; 47(7): 3365–3382. Published online 2019 Jan 30. doi: 10.1093/nar/gkz041

PMCID:: PMC6468246

Abstract Article PDF–4.4M

Select item 629825413.

A protein-protein interaction map of the TNF-induced NF-κB signal transduction pathway

Emmy Van Quickelberghe, Delphine De Sutter, Geert van Loo, Sven Eyckerman, Kris Gevaert

Sci Data. 2018; 5: 180289. Published online 2018 Dec 18. doi: 10.1038/sdata.2018.289

PMCID:: PMC6298254

Abstract Article PDF–1.4M

Select item 616668214.

Histone Interaction Landscapes Visualized by Crosslinking Mass Spectrometry in Intact Cell Nuclei

Domenico Fasci, Hugo van Ingen, Richard A. Scheltema, Albert J. R. Heck

Mol Cell Proteomics. 2018 Oct; 17(10): 2018–2033. Published online 2018 Jul 18. doi: 10.1074/mcp.RA118.000924

PMCID:: PMC6166682

Abstract Article PDF–3.8M

Select item 605980615.

Measuring sulfatase expression and invasion in glioblastoma

Anna Wade, Jane R. Engler, Vy My Tran, Joanna J. Phillips

Methods Mol Biol. Author manuscript; available in PMC 2018 Jul 25.

Published in final edited form as: Methods Mol Biol. 2015; 1229: 507–516. doi: 10.1007/978-1-4939-1714-3_39

PMCID:: PMC6059806

Abstract Article PDF–565K

Select item 583915816.

Quantitative mapping of RNA-mediated nuclear estrogen receptor β interactome in human breast cancer cells

Giorgio Giurato, Giovanni Nassa, Annamaria Salvati, Elena Alexandrova, Francesca Rizzo, Tuula A. Nyman, Alessandro Weisz, Roberta Tarallo

Sci Data. 2018; 5: 180031. Published online 2018 Mar 6. doi: 10.1038/sdata.2018.31

PMCID:: PMC5839158

Abstract Article PDF–1.9M

Select item 582692617.

VIRMA mediates preferential m⁶A mRNA methylation in 3′UTR and near stop codon and associates with alternative polyadenylation

Yanan Yue, Jun Liu, Xiaolong Cui, Jie Cao, Guanzheng Luo, Zezhou Zhang, Tao Cheng, Minsong Gao, Xiao Shu, Honghui Ma, Fengqin Wang, Xinxia Wang, Bin Shen, Yizhen Wang, Xinhua Feng, Chuan He, Jianzhao Liu

Cell Discov. 2018; 4: 10. Published online 2018 Feb 27. doi: 10.1038/s41421-018-0019-0

PMCID:: PMC5826926

Abstract Article PDF–2.3M

Select item 565386118.

Desulfation of Heparan Sulfate by Sulf1 and Sulf2 Is Required for Corticospinal Tract Formation

Takuya Okada, Kazuko Keino-Masu, Satoshi Nagamine, Fuyuki Kametani, Tatsuyuki Ohto, Masato Hasegawa, Toin H. van Kuppevelt, Satoshi Kunita, Satoru Takahashi, Masayuki Masu

Sci Rep. 2017; 7: 13847. Published online 2017 Oct 23. doi: 10.1038/s41598-017-14185-3

PMCID:: PMC5653861

Abstract Article PDF–5.0M

Select item 553161119.

Architecture of the human interactome defines protein communities and disease networks

Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper

Nature. Author manuscript; available in PMC 2017 Nov 17.

Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366

PMCID:: PMC5531611

Abstract Article PDF–2.7M

Select item 519001620.

Expression of the extracellular sulfatase SULF2 is associated with squamous cell carcinoma of the head and neck

Sarah A. Flowers, Xin Zhou, Jing Wu, Yiwen Wang, Kepher Makambi, Bhaskar V. Kallakury, Mark S. Singer, Steven D. Rosen, Bruce Davidson, Radoslav Goldman

Oncotarget. 2016 Jul 12; 7(28): 43177–43187. Published online 2016 May 20. doi: 10.18632/oncotarget.9506

PMCID:: PMC5190016

Abstract Article PDF–5.4M

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PMC Links for GEO Profiles (Select 103813571) (59)
PMC
Nucleotide Links for Gene (Select 7482) (18)
Nucleotide
Homo sapiens TP53 activated protein 1, mRNA (cDNA clone IMAGE:6604080)
Homo sapiens TP53 activated protein 1, mRNA (cDNA clone IMAGE:6604080)
gi|73909167|gb|BC103631.1|

Nucleotide
668902[uid] (1)
Taxonomy
protein Wnt-2b isoform WNT-2B2 [Homo sapiens]
protein Wnt-2b isoform WNT-2B2 [Homo sapiens]
gi|13518021|ref|NP_078613.1|

Protein

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