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Select item 85529071.

SARS‐CoV‐2–host proteome interactions for antiviral drug discovery

Xiaonan Liu, Sini Huuskonen, Tuomo Laitinen, Taras Redchuk, Mariia Bogacheva, Kari Salokas, Ina Pöhner, Tiina Öhman, Arun Kumar Tonduru, Antti Hassinen, Lisa Gawriyski, Salla Keskitalo, Maria K Vartiainen, Vilja Pietiäinen, Antti Poso, Markku Varjosalo

Mol Syst Biol. 2021 Nov; 17(11): e10396. Published online 2021 Oct 28. doi: 10.15252/msb.202110396

PMCID:: PMC8552907

Abstract Article PDF–3.9M

Select item 83537472.

A case-control study on correlation between the single nucleotide polymorphism of CLEC4E and the susceptibility to tuberculosis among Han people in Western China

Wenjing Zhou, Lijuan Wu, Jiajia Song, Lin Jiao, Yi Zhou, Juan Zhou, Nian Wang, Tangyuheng Liu, Zhenzhen Zhao, Hao Bai, Tao Wu, Binwu Ying

BMC Infect Dis. 2021; 21: 788. Published online 2021 Aug 10. doi: 10.1186/s12879-021-06448-2

PMCID:: PMC8353747

Abstract Article PDF–671K

Select item 81650303.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 79625424.

CLEC4E (Mincle) genetic variation associates with pulmonary tuberculosis in Guinea-Bissau (West Africa)

Jasmine M. Olvany, Lindsay N. Sausville, Marquitta J. White, Alessandra Tacconelli, Gloria Tavera, Rafal S. Sobota, Cinzia Ciccacci, Anders S. Bohlbro, Christian Wejse, Scott M. Williams, Giorgio Sirugo

Infect Genet Evol. Author manuscript; available in PMC 2021 Nov 1.

Published in final edited form as: Infect Genet Evol. 2020 Nov; 85: 104560. Published online 2020 Sep 22. doi: 10.1016/j.meegid.2020.104560

PMCID:: PMC7962542

Abstract Article PDF–827K

Select item 73868285.

Age-specific Adjuvant Synergy: Dual TLR7/8 and Mincle Activation of Human Newborn Dendritic Cells Enables Th1-polarization

Simon D. van Haren, David J. Dowling, Willemina Foppen, Dennis Christensen, Peter Andersen, Steven G. Reed, Robert M. Hershberg, Lindsey R Baden, Ofer Levy

J Immunol. Author manuscript; available in PMC 2020 Jul 28.

Published in final edited form as: J Immunol. 2016 Dec 1; 197(11): 4413–4424. Published online 2016 Oct 28. doi: 10.4049/jimmunol.1600282

PMCID:: PMC7386828

Abstract Article PDF–1.6M

Select item 73220676.

RIG-I regulates myeloid differentiation by promoting TRIM25-mediated ISGylation

Song-Fang Wu, Li Xia, Xiao-Dong Shi, Yu-Jun Dai, Wei-Na Zhang, Jun-Mei Zhao, Wu Zhang, Xiang-Qin Weng, Jing Lu, Huang-Ying Le, Sheng-ce Tao, Jiang Zhu, Zhu Chen, Yue-Ying Wang, Saijuan Chen

Proc Natl Acad Sci U S A. 2020 Jun 23; 117(25): 14395–14404. Published online 2020 Jun 8. doi: 10.1073/pnas.1918596117

PMCID:: PMC7322067

Abstract Article PDF–2.7M

Select item 71699837.

A reference map of the human binary protein interactome

Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood

Nature. Author manuscript; available in PMC 2020 Oct 8.

Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x

PMCID:: PMC7169983

Abstract Article PDF–5.4M

Select item 65911548.

Expression and function of macrophage‐inducible C‐type lectin (Mincle) in inflammation driven parturition in fetal membranes and myometrium

R. Lim, M. Lappas

Clin Exp Immunol. 2019 Jul; 197(1): 95–110. Published online 2019 Mar 13. doi: 10.1111/cei.13281

PMCID:: PMC6591154

Abstract Article PDF–1.6M

Select item 55316119.

Architecture of the human interactome defines protein communities and disease networks

Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper

Nature. Author manuscript; available in PMC 2017 Nov 17.

Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366

PMCID:: PMC5531611

Abstract Article PDF–2.7M

Select item 514007110.

C-type Lectin Mincle Recognizes Glucosyl-diacylglycerol of Streptococcus pneumoniae and Plays a Protective Role in Pneumococcal Pneumonia

Friederike Behler-Janbeck, Tomotsugu Takano, Regina Maus, Jennifer Stolper, Danny Jonigk, Meritxell Tort Tarrés, Thomas Fuehner, Antje Prasse, Tobias Welte, Mattie S. M. Timmer, Bridget L. Stocker, Yoichi Nakanishi, Tomofumi Miyamoto, Sho Yamasaki, Ulrich A. Maus

PLoS Pathog. 2016 Dec; 12(12): e1006038. Published online 2016 Dec 6. doi: 10.1371/journal.ppat.1006038

PMCID:: PMC5140071

Abstract Article PDF–4.6M

Select item 464794111.

hORFeome v3.1: A resource of human open reading frames representing over 10,000 human genes

Philippe Lamesch, Ning Li, Stuart Milstein, Changyu Fan, Tong Hao, Gabor Szabo, Zhenjun Hu, Kavitha Venkatesan, Graeme Bethel, Paul Martin, Jane Rogers, Stephanie Lawlor, Stuart McLaren, Amélie Dricot, Heather Borick, Michael E. Cusick, Jean Vandenhaute, Ian Dunham, David E. Hill, Marc Vidal

Genomics. 2007 Mar; 89(3): 307–315. doi: 10.1016/j.ygeno.2006.11.012

PMCID:: PMC4647941

Abstract Article

Select item 464618212.

Human Mincle Binds to Cholesterol Crystals and Triggers Innate Immune Responses

Ryoko Kiyotake, Masatsugu Oh-hora, Eri Ishikawa, Tomofumi Miyamoto, Tatsuro Ishibashi, Sho Yamasaki

J Biol Chem. 2015 Oct 16; 290(42): 25322–25332. Published online 2015 Aug 20. doi: 10.1074/jbc.M115.645234

PMCID:: PMC4646182

Abstract Article PDF–1.9M

Select item 460102113.

Induction of Mincle by Helicobacter pylori and consequent anti-inflammatory signaling denote a bacterial survival strategy

Savita Devi, Eerappa Rajakumara, Niyaz Ahmed

Sci Rep. 2015; 5: 15049. Published online 2015 Oct 12. doi: 10.1038/srep15049

PMCID:: PMC4601021

Abstract Article PDF–1.4M

Select item 414089714.

Glycerol Monomycolate Is a Novel Ligand for the Human, but Not Mouse Macrophage Inducible C-type Lectin, Mincle

Yuki Hattori, Daisuke Morita, Nagatoshi Fujiwara, Daiki Mori, Takashi Nakamura, Hideyoshi Harashima, Sho Yamasaki, Masahiko Sugita

J Biol Chem. 2014 May 30; 289(22): 15405–15412. Published online 2014 Apr 13. doi: 10.1074/jbc.M114.566489

PMCID:: PMC4140897

Abstract Article PDF–1.1M

Select item 380864115.

Structural analysis for glycolipid recognition by the C-type lectins Mincle and MCL

Atsushi Furukawa, Jun Kamishikiryo, Daiki Mori, Kenji Toyonaga, Yuki Okabe, Aya Toji, Ryo Kanda, Yasunobu Miyake, Toyoyuki Ose, Sho Yamasaki, Katsumi Maenaka

Proc Natl Acad Sci U S A. 2013 Oct 22; 110(43): 17438–17443. Published online 2013 Oct 7. doi: 10.1073/pnas.1312649110

PMCID:: PMC3808641

Abstract Article PDF–1.6M

Select item 344370416.

Mincle and human B cell function

Kazuhito Kawata, Petr Illarionov, Thomas Kenny, Weici Zhang, Masanobu Tsuda, Yugo Ando, Patrick Leung, Aftab A. Ansari, M. Eric Gershwin

J Autoimmun. Author manuscript; available in PMC 2013 Dec 1.

Published in final edited form as: J Autoimmun. 2012 Dec; 39(4): 315–322. Published online 2012 Jun 12. doi: 10.1016/j.jaut.2012.04.004

PMCID:: PMC3443704

Abstract Article PDF–2.4M

Select item 331660817.

Silencing of Renal DNaseI in Murine Lupus Nephritis Imposes Exposure of Large Chromatin Fragments and Activation of Toll Like Receptors and the Clec4e

Dhivya Thiyagarajan, Silje Fismen, Natalya Seredkina, Søren Jacobsen, Thomas Elung-Jensen, Anne-Lise Kamper, Christopher Graham Fenton, Ole Petter Rekvig, Elin Synnøve Mortensen

PLoS One. 2012; 7(3): e34080. Published online 2012 Mar 30. doi: 10.1371/journal.pone.0034080

PMCID:: PMC3316608

Abstract Article PDF–2.3M

Select item 317805918.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 304684219.

Increased Expression of Macrophage-Inducible C-type Lectin in Adipose Tissue of Obese Mice and Humans

Masayuki Ichioka, Takayoshi Suganami, Naoto Tsuda, Ibuki Shirakawa, Yoichiro Hirata, Noriko Satoh-Asahara, Yuri Shimoda, Miyako Tanaka, Misa Kim-Saijo, Yoshihiro Miyamoto, Yasutomi Kamei, Masataka Sata, Yoshihiro Ogawa

Diabetes. 2011 Mar; 60(3): 819–826. Published online 2011 Feb 21. doi: 10.2337/db10-0864

PMCID:: PMC3046842

Abstract Article PDF–1.0M

Select item 135612920.

Diversification of transcriptional modulation: Large-scale identification and characterization of putative alternative promoters of human genes

Kouichi Kimura, Ai Wakamatsu, Yutaka Suzuki, Toshio Ota, Tetsuo Nishikawa, Riu Yamashita, Jun-ichi Yamamoto, Mitsuo Sekine, Katsuki Tsuritani, Hiroyuki Wakaguri, Shizuko Ishii, Tomoyasu Sugiyama, Kaoru Saito, Yuko Isono, Ryotaro Irie, Norihiro Kushida, Takahiro Yoneyama, Rie Otsuka, Katsuhiro Kanda, Takahide Yokoi, Hiroshi Kondo, Masako Wagatsuma, Katsuji Murakawa, Shinichi Ishida, Tadashi Ishibashi, Asako Takahashi-Fujii, Tomoo Tanase, Keiichi Nagai, Hisashi Kikuchi, Kenta Nakai, Takao Isogai, Sumio Sugano

Genome Res. 2006 Jan; 16(1): 55–65. doi: 10.1101/gr.4039406

PMCID:: PMC1356129

Abstract Article PDF–438K

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