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Select item 106182471.

Apelin is expressed in intimal smooth muscle cells and promotes their phenotypic transition

Luís Miguel Cardoso Dos Santos, Pascal Azar, Cécile Brun, Stéphane König, Angela Roatti, Alex J. Baertschi, Chiraz Chaabane, Marie-Luce Bochaton-Piallat

Sci Rep. 2023; 13: 18736. Published online 2023 Oct 31. doi: 10.1038/s41598-023-45470-z

PMCID:: PMC10618247

Abstract Article PDF–4.7M

Select item 94526942.

Possible roles of exercise and apelin against pregnancy complications

Hamed Alizadeh Pahlavani

Front Endocrinol (Lausanne) 2022; 13: 965167. Published online 2022 Aug 25. doi: 10.3389/fendo.2022.965167

PMCID:: PMC9452694

Abstract Article PDF–1020K

Select item 69285223.

Pioglitazone protects blood vessels through inhibition of the apelin signaling pathway by promoting KLF4 expression in rat models of T2DM

Ying Wang, Ruonan Zhang, Hailin Shen, Jing Kong, Xinrui Lv

Biosci Rep. 2019 Dec 20; 39(12): BSR20190317. Published online 2019 Dec 24. doi: 10.1042/BSR20190317

PMCID:: PMC6928522

Abstract Article PDF–2.3M

Select item 62758934.

Ischemic heart failure enhances endogenous myocardial apelin and APJ receptor expression

Pavan Atluri, Kevin J. Morine, George P. Liao, Corinna M. Panlilio, Mark F. Berry, Vivian M. Hsu, William Hiesinger, Jeffrey E. Cohen, Y. Joseph Woo

Cell Mol Biol Lett. 2007 Mar; 12(1): 127–138. Published online 2006 Nov 19. doi: 10.2478/s11658-006-0058-7

PMCID:: PMC6275893

Summary PDF–510K

Select item 58950865.

Alternative Progenitor Cells Compensate to Rebuild the Coronary Vasculature in Elabela- and Apj-Deficient Hearts

Bikram Sharma, Lena Ho, Gretchen Hazel Ford, Heidi I. Chen, Andrew B. Goldstone, Y. Joseph Woo, Thomas Quertermous, Bruno Reversade, Kristy Red-Horse

Dev Cell. Author manuscript; available in PMC 2018 Apr 11.

Published in final edited form as: Dev Cell. 2017 Sep 25; 42(6): 655–666.e3. Published online 2017 Sep 7. doi: 10.1016/j.devcel.2017.08.008

PMCID:: PMC5895086

Abstract Article PDF–3.6M

Select item 57266096.

Load-dependent effects of apelin on murine cardiomyocytes

Rémi Peyronnet, Christian Bollensdorff, Rebecca A. Capel, Eva A. Rog-Zielinska, Christopher E. Woods, David N. Charo, Oleg Lookin, Giovanni Fajardo, Michael Ho, Thomas Quertermous, Euan A. Ashley, Peter Kohl

Prog Biophys Mol Biol. 2017 Nov; 130(Pt B): 333–343. doi: 10.1016/j.pbiomolbio.2017.09.013

PMCID:: PMC5726609

Abstract Article PDF–1.9M

Select item 55620647.

Effect of the spinal apelin-APJ system on the pathogenesis of chronic constriction injury-induced neuropathic pain in rats

Qingming Xiong, Wanyou He, Hanbing Wang, Jun Zhou, Yajun Zhang, Jian He, Chengxiang Yang, Bin Zhang

Mol Med Rep. 2017 Aug; 16(2): 1223–1231. Published online 2017 Jun 9. doi: 10.3892/mmr.2017.6734

PMCID:: PMC5562064

Abstract Article PDF–1.4M

Select item 53638378.

Elabela/Toddler Is an Endogenous Agonist of the Apelin APJ Receptor in the Adult Cardiovascular System, and Exogenous Administration of the Peptide Compensates for the Downregulation of Its Expression in Pulmonary Arterial Hypertension

Peiran Yang, Cai Read, Rhoda E. Kuc, Guido Buonincontri, Mark Southwood, Rubben Torella, Paul D. Upton, Alexi Crosby, Stephen J. Sawiak, T. Adrian Carpenter, Robert C. Glen, Nicholas W. Morrell, Janet J. Maguire, Anthony P. Davenport

Circulation. 2017 Mar 21; 135(12): 1160–1173. Published online 2017 Mar 20. doi: 10.1161/CIRCULATIONAHA.116.023218

PMCID:: PMC5363837

Abstract Article PDF–2.3M

Select item 52909639.

Apelin-36 Modulates Blood Glucose and Body Weight Independently of Canonical APJ Receptor Signaling

Hadas Galon-Tilleman, Hong Yang, Maria A. Bednarek, Sandra M. Spurlock, Kevin J. Paavola, Brian Ko, Carmen To, Jian Luo, Hui Tian, Lutz Jermutus, Joseph Grimsby, Cristina M. Rondinone, Anish Konkar, Daniel D. Kaplan

J Biol Chem. 2017 Feb 3; 292(5): 1925–1933. Published online 2016 Dec 19. doi: 10.1074/jbc.M116.748103

PMCID:: PMC5290963

Abstract Article PDF–1.9M

Select item 451308710.

Apela Regulates Fluid Homeostasis by Binding to the APJ Receptor to Activate Gi Signaling

Cheng Deng, Haidi Chen, Na Yang, Yi Feng, Aaron J. W. Hsueh

J Biol Chem. 2015 Jul 24; 290(30): 18261–18268. Published online 2015 May 20. doi: 10.1074/jbc.M115.648238

PMCID:: PMC4513087

Abstract Article PDF–1.5M

Select item 450553411.

Apelin Enhances Brown Adipogenesis and Browning of White Adipocytes

Aung Than, Hui Ling He, Si Hui Chua, Dan Xu, Lei Sun, Melvin Khee-Shing Leow, Peng Chen

J Biol Chem. 2015 Jun 5; 290(23): 14679–14691. Published online 2015 Apr 30. doi: 10.1074/jbc.M115.643817

PMCID:: PMC4505534

Abstract Article PDF–4.4M

Select item 416098712.

Regulation of Apelin and Its Receptor Expression in Adipose Tissues of Obesity Rats with Hypertension and Cultured 3T3-L1 Adipocytes

Hongxian Wu, Xian Wu Cheng, Changning Hao, Zhi Zhang, Huali Yao, Toyoaki Murohara, Qiuyan Dai

Exp Anim. 2014; 63(2): 257–267. Published online 2014 Apr 26. doi: 10.1538/expanim.63.257

PMCID:: PMC4160987

Abstract Article PDF–1.0M

Select item 414888313.

Biased Signaling Favoring G_i over β-Arrestin Promoted by an Apelin Fragment Lacking the C-terminal Phenylalanine

Emilie Ceraudo, Cécile Galanth, Eric Carpentier, Inmaculada Banegas-Font, Anne-Marie Schonegge, Rodrigo Alvear-Perez, Xavier Iturrioz, Michel Bouvier, Catherine Llorens-Cortes

J Biol Chem. 2014 Aug 29; 289(35): 24599–24610. Published online 2014 Jul 10. doi: 10.1074/jbc.M113.541698

PMCID:: PMC4148883

Abstract Article PDF–1.2M

Select item 387330114.

Apelin-13 Inhibits Large-Conductance Ca²⁺-Activated K⁺ Channels in Cerebral Artery Smooth Muscle Cells via a PI3-Kinase Dependent Mechanism

Amit Modgil, Lirong Guo, Stephen T. O’Rourke, Chengwen Sun

PLoS One. 2013; 8(12): e83051. Published online 2013 Dec 26. doi: 10.1371/journal.pone.0083051

PMCID:: PMC3873301

Abstract Article PDF–619K

Select item 372615315.

FK506 activates BMPR2, rescues endothelial dysfunction, and reverses pulmonary hypertension

Edda Spiekerkoetter, Xuefei Tian, Jie Cai, Rachel K. Hopper, Deepti Sudheendra, Caiyun G. Li, Nesrine El-Bizri, Hirofumi Sawada, Roxanna Haghighat, Roshelle Chan, Leila Haghighat, Vinicio de Jesus Perez, Lingli Wang, Sushma Reddy, Mingming Zhao, Daniel Bernstein, David E. Solow-Cordero, Philip A. Beachy, Thomas J. Wandless, Peter ten Dijke, Marlene Rabinovitch

J Clin Invest. 2013 Aug 1; 123(8): 3600–3613. Published online 2013 Jul 15. doi: 10.1172/JCI65592

PMCID:: PMC3726153

Abstract Article PDF–3.6M

Select item 371723616.

Apelin acts in the subfornical organ to influence neuronal excitability and cardiovascular function

Li Dai, Pauline M Smith, Markus Kuksis, Alastair V Ferguson

J Physiol. 2013 Jul 1; 591(Pt 13): 3421–3432. Published online 2013 Apr 29. doi: 10.1113/jphysiol.2013.254144

PMCID:: PMC3717236

Abstract Article PDF–897K

Select item 371303317.

The Role of Apelin in the Retina of Diabetic Rats

Qiang Lu, Jing Feng, Yan-rong Jiang

PLoS One. 2013; 8(7): e69703. Published online 2013 Jul 16. doi: 10.1371/journal.pone.0069703

PMCID:: PMC3713033

Abstract Article PDF–573K

Select item 354016818.

Endothelial Apelin-FGF Link Mediated by MicroRNAs 424 and 503 is Disrupted in Pulmonary Arterial Hypertension

Jongmin Kim, Yujung Kang, Yoko Kojima, Janet K. Lighthouse, Xiaoyue Hu, Micheala A. Aldred, Danielle L. McLean, Hyekyung Park, Suzy A. Comhair, Daniel M. Greif, Serpil C. Erzurum, Hyung J. Chun

Nat Med. Author manuscript; available in PMC 2013 Jul 1.

Published in final edited form as: Nat Med. 2013 Jan; 19(1): 74–82. Published online 2012 Dec 23. doi: 10.1038/nm.3040