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Select item 103419661.

KDM6B Negatively Regulates the Neurogenesis Potential of Apical Papilla Stem Cells via HES1

Chen Zhang, Weilong Ye, Mengyao Zhao, Lujue Long, Dengsheng Xia, Zhipeng Fan

Int J Mol Sci. 2023 Jul; 24(13): 10608. Published online 2023 Jun 25. doi: 10.3390/ijms241310608

PMCID:: PMC10341966

Abstract Article PDF–6.4M

Select item 87502012.

Determination of Relative Notch1 and γ-Secretase-Related Gene Expression in Puromycin-Treated Microdissected Rat Kidneys

Damir Simic, Frank Simutis, Catherine Euler, Christina Thurby, W. Mike Peden, R. Todd Bunch, Gary Pilcher, Thomas Sanderson, Terry Van Vleet

Gene Expr. 2013; 16(1): 39–47. Published online 2013 Dec 3. doi: 10.3727/105221613X13806435102312

PMCID:: PMC8750201

Abstract Article PDF–36M

Select item 67623423.

Hes1 and Hes5 Activities Are Required for the Normal Development of the Hair Cells in the Mammalian Inner Ear

Azel Zine, Alexandre Aubert, Jiping Qiu, Stavros Therianos, Francois Guillemot, Ryoichiro Kageyama, Francois de Ribaupierre

J Neurosci. 2001 Jul 1; 21(13): 4712–4720. doi: 10.1523/JNEUROSCI.21-13-04712.2001

PMCID:: PMC6762342

Abstract Article PDF–2.1M

Select item 67470684.

Transcription Repressor Hes1 Contributes to Neuropathic Pain Development by Modifying CDK9/RNAPII-Dependent Spinal mGluR5 Transcription

Ming-Chun Hsieh, Hsien-Yu Peng, Yu-Cheng Ho, Cheng-Yuan Lai, Jen-Kun Cheng, Gin-Den Chen, Tzer-Bin Lin

Int J Mol Sci. 2019 Sep; 20(17): 4177. Published online 2019 Aug 26. doi: 10.3390/ijms20174177

PMCID:: PMC6747068

Abstract Article PDF–6.1M

Select item 67033585.

JNK1 Inhibits GluR1 Expression and GluR1-Mediated Calcium Influx through Phosphorylation and Stabilization of Hes-1

Cheng H. Lin, Eminy H. Y. Lee

J Neurosci. 2012 Feb 1; 32(5): 1826–1846. doi: 10.1523/JNEUROSCI.3380-11.2012

PMCID:: PMC6703358

Abstract Article PDF–7.0M

Select item 64527116.

Triggering of a Dll4–Notch1 loop impairs wound healing in diabetes

Xiaowei Zheng, Sampath Narayanan, Vivekananda Gupta Sunkari, Sofie Eliasson, Ileana Ruxandra Botusan, Jacob Grünler, Anca Irinel Catrina, Freddy Radtke, Cheng Xu, Allan Zhao, Neda Rajamand Ekberg, Urban Lendahl, Sergiu-Bogdan Catrina

Proc Natl Acad Sci U S A. 2019 Apr 2; 116(14): 6985–6994. Published online 2019 Mar 18. doi: 10.1073/pnas.1900351116

PMCID:: PMC6452711

Abstract Article PDF–2.3M

Select item 64108717.

NOTCH1 signaling induces pathological vascular permeability in diabetic retinopathy

Khalil Miloudi, Malika Oubaha, Catherine Ménard, Agnieszka Dejda, Vera Guber, Gael Cagnone, Ariel M. Wilson, Nicolas Tétreault, Gaëlle Mawambo, Francois Binet, Rony Chidiac, Chantal Delisle, Manuel Buscarlet, Agustin Cerani, Sergio Crespo-Garcia, Katie Bentley, Flavio Rezende, Jean-Sebastien Joyal, Frédérick A. Mallette, Jean-Philippe Gratton, Bruno Larrivée, Przemyslaw Sapieha

Proc Natl Acad Sci U S A. 2019 Mar 5; 116(10): 4538–4547. Published online 2019 Feb 20. doi: 10.1073/pnas.1814711116

PMCID:: PMC6410871

Abstract Article PDF–3.2M

Select item 58410868.

High-content genome-wide RNAi screens identify regulators of parkin upstream of mitophagy

Samuel A. Hasson, Lesley A. Kane, Koji Yamano, Chiu-Hui Huang, Danielle A. Sliter, Eugen Buehler, Chunxin Wang, Sabrina M. Heman-Ackah, Tara Hessa, Rajarshi Guha, Scott E. Martin, Richard J. Youle

Nature. Author manuscript; available in PMC 2018 Mar 7.

Published in final edited form as: Nature. 2013 Dec 12; 504(7479): 291–295. Published online 2013 Nov 24. doi: 10.1038/nature12748

PMCID:: PMC5841086

Abstract Article PDF–5.3M

Select item 55922449.

Wnt-Dependent Inactivation of the Groucho/TLE Co-repressor by the HECT E3 Ubiquitin Ligase Hyd/UBR5

Joshua E. Flack, Juliusz Mieszczanek, Nikola Novcic, Mariann Bienz

Mol Cell. 2017 Jul 20; 67(2): 181–193.e5. doi: 10.1016/j.molcel.2017.06.009

PMCID:: PMC5592244

Abstract Article

Select item 429934010.

Hes1, an important gene for activation of hepatic stellate cells, is regulated by Notch1 and TGF-β/BMP signaling

Kai Zhang, Yan-Qiong Zhang, Wen-Bing Ai, Qing-Ting Hu, Qiao-Juan Zhang, Lin-Yan Wan, Xiao-Lian Wang, Chang-Bai Liu, Jiang-Feng Wu

World J Gastroenterol. 2015 Jan 21; 21(3): 878–887. Published online 2015 Jan 21. doi: 10.3748/wjg.v21.i3.878

PMCID:: PMC4299340

Abstract Article PDF–1.2M

Select item 429167311.

Notch inhibition induces mitotically generated hair cells in mammalian cochleae via activating the Wnt pathway

Wenyan Li, Jingfang Wu, Jianming Yang, Shan Sun, Renjie Chai, Zheng-Yi Chen, Huawei Li

Proc Natl Acad Sci U S A. 2015 Jan 6; 112(1): 166–171. Published online 2014 Dec 22. doi: 10.1073/pnas.1415901112

PMCID:: PMC4291673

Abstract Article PDF–1.7M

Select item 412841412.

Multiple requirements for Hes1 during early eye formation

Hae Young Lee, Emily Wroblewski, Gary T. Philips, Carrie N. Stair, Kevin Conley, Meredith Reedy, Grant S. Mastick, Nadean L. Brown

Dev Biol. Author manuscript; available in PMC 2014 Aug 11.

Published in final edited form as: Dev Biol. 2005 Aug 15; 284(2): 464–478. doi: 10.1016/j.ydbio.2005.06.010

PMCID:: PMC4128414

Abstract Article PDF–3.2M

Select item 399707213.

HES1 Is a Master Regulator of Glucocorticoid Receptor-Dependent Gene Expression

Javier R. Revollo, Robert H. Oakley, Nick Z. Lu, Mahita Kadmiel, Maheer Gandhavadi, John A. Cidlowski

Sci Signal. Author manuscript; available in PMC 2014 Apr 23.

Published in final edited form as: Sci Signal. 2013 Dec 3; 6(304): ra103. Published online 2013 Dec 3. doi: 10.1126/scisignal.2004389

PMCID:: PMC3997072

Abstract Article PDF–1.2M

Select item 378970814.

The Jagged-2/Notch-1/Hes-1 Pathway Is Involved in Intestinal Epithelium Regeneration after Intestinal Ischemia-Reperfusion Injury

Guoqing Chen, Yuan Qiu, Lihua Sun, Min Yu, Wensheng Wang, Weidong Xiao, Yang Yang, Yong Liu, Songwei Yang, Daniel H. Teitelbaum, Yuanhang Ma, Dingsong Lu, Hua Yang

PLoS One. 2013; 8(10): e76274. Published online 2013 Oct 3. doi: 10.1371/journal.pone.0076274

PMCID:: PMC3789708

Abstract Article PDF–8.3M

Select item 367560915.

Inflammatory Cytokines Induce NOTCH Signaling in Nucleus Pulposus Cells: IMPLICATIONS IN INTERVERTEBRAL DISC DEGENERATION

Hua Wang, Ye Tian, Jianru Wang, Kate L. E. Phillips, Abbie L. A. Binch, Sara Dunn, Alison Cross, Neil Chiverton, Zhaomin Zheng, Irving M. Shapiro, Christine L. Le Maitre, Makarand V. Risbud

J Biol Chem. 2013 Jun 7; 288(23): 16761–16774. Published online 2013 Apr 15. doi: 10.1074/jbc.M112.446633

PMCID:: PMC3675609

Abstract Article PDF–6.2M

Select item 352408716.

Ascl1 (Mash1) Knockout Perturbs Differentiation of Nonneuronal Cells in Olfactory Epithelium

Richard C. Krolewski, Adam Packard, Woochan Jang, Hendrik Wildner, James E. Schwob

PLoS One. 2012; 7(12): e51737. Published online 2012 Dec 17. doi: 10.1371/journal.pone.0051737

PMCID:: PMC3524087

Abstract Article PDF–10M

Select item 346522517.

Electroacupuncture pretreatment induces tolerance against focal cerebral ischemia through activation of canonical Notch pathway

Yu Zhao, Xiyao Chen, Lei Ma, Zhiyi Zuo, Zhenghua Zhu, Xiaoling Zhu, Qiang Wang, Ertao He, Lize Xiong, Jianming Pei, Lixian Xu, Lihong Hou, Shaoyang Chen

BMC Neurosci. 2012; 13: 111. Published online 2012 Sep 19. doi: 10.1186/1471-2202-13-111