U.S. flag

An official website of the United States government

Display Settings:

Format
Items per page
Sort by

Send to:

Choose Destination

Links from GEO Profiles

Items: 1 to 20 of 82

1.
TPP1 is associated with risk of advanced precursors and cervical cancer survival
Qiao-Li Wang, Caifeng Gong, Xiang-Yu Meng, Min Fu, Hui Yang, Fuxiang Zhou, Qiuji Wu, Yunfeng Zhou
PLoS One. 2024; 19(5): e0298118. Published online 2024 May 9. doi: 10.1371/journal.pone.0298118
PMCID:
PMC11081309
AbstractArticlePDF–2.0M
2.
TPP1 promoter mutations cooperate with TERT promoter mutations to lengthen telomeres in melanoma
Pattra Chun-on, Angela M. Hinchie, Holly C. Beale, Agustin A. Gil Silva, Elizabeth Rush, Cindy Sander, Carla J. Connelly, Brittani K.N. Seynnaeve, John M. Kirkwood, Olena M. Vaske, Carol W. Greider, Jonathan K. Alder
Science. Author manuscript; available in PMC 2023 Oct 22.
Published in final edited form as: Science. 2022 Nov 11; 378(6620): 664–668. Published online 2022 Nov 10. doi: 10.1126/science.abq0607
PMCID:
PMC10590476
AbstractArticlePDF–1.0M
3.
CTC1 OB-B interaction with TPP1 terminates telomerase and prevents telomere overextension
Huan Wang, Tengfei Ma, Xiaotong Zhang, Wei Chen, Yina Lan, Guotao Kuang, Shih-Jui Hsu, Zibin He, Yuxi Chen, Jason Stewart, Anukana Bhattacharjee, Zhenhua Luo, Carolyn Price, Xuyang Feng
Nucleic Acids Res. 2023 Jun 9; 51(10): 4914–4928. Published online 2023 Apr 6. doi: 10.1093/nar/gkad237
PMCID:
PMC10250220
AbstractArticlePDF–3.0M
4.
Complex interaction network revealed by mutation of human telomerase ‘insertion in fingers’ and essential N-terminal domains and the telomere protein TPP1
Patrick Lambert-Lanteigne, Adrian Young, Chantal Autexier
J Biol Chem. 2023 Mar; 299(3): 102916. Published online 2023 Jan 14. doi: 10.1016/j.jbc.2023.102916
PMCID:
PMC9958494
AbstractArticlePDF–2.5M
5.
Structure of active human telomerase with telomere shelterin protein TPP1
Baocheng Liu, Yao He, Yaqiang Wang, He Song, Z. Hong Zhou, Juli Feigon
Nature. Author manuscript; available in PMC 2023 Feb 10.
Published in final edited form as: Nature. 2022 Apr; 604(7906): 578–583. Published online 2022 Apr 13. doi: 10.1038/s41586-022-04582-8
PMCID:
PMC9912816
AbstractArticlePDF–3.6M
6.
Genome-wide CRISPR screens using isogenic cells reveal vulnerabilities conferred by loss of tumor suppressors
Xu Feng, Mengfan Tang, Merve Dede, Dan Su, Guangsheng Pei, Dadi Jiang, Chao Wang, Zhen Chen, Mi Li, Litong Nie, Yun Xiong, Siting Li, Jeong-Min Park, Huimin Zhang, Min Huang, Klaudia Szymonowicz, Zhongming Zhao, Traver Hart, Junjie Chen
Sci Adv. 2022 May; 8(19): eabm6638. Published online 2022 May 13. doi: 10.1126/sciadv.abm6638
PMCID:
PMC9106303
AbstractArticlePDF–918K
7.
Multiple hPOT1–TPP1 cooperatively unfold contiguous telomeric G-quadruplexes proceeding from 3′ toward 5′, a feature due to a 3′-end binding preference and to structuring of telomeric DNA
Jean Chatain, Georges Hatem, Emmanuelle Delagoutte, Jean-François Riou, Patrizia Alberti, Carole Saintomé
Nucleic Acids Res. 2021 Oct 11; 49(18): 10735–10746. Published online 2021 Sep 17. doi: 10.1093/nar/gkab768
PMCID:
PMC8501996
AbstractArticlePDF–3.0M
8.
TPP1 mutagenesis screens unravel shelterin interfaces and functions in hematopoiesis
Sherilyn Grill, Shilpa Padmanaban, Ann Friedman, Eric Perkey, Frederick Allen, Valerie M. Tesmer, Jennifer Chase, Rami Khoriaty, Catherine E. Keegan, Ivan Maillard, Jayakrishnan Nandakumar
JCI Insight. 2021 May 10; 6(9): e138059. Published online 2021 May 10. doi: 10.1172/jci.insight.138059
PMCID:
PMC8262337
AbstractArticlePDF–2.7M
9.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
10.
DNA Repair Network Analysis Reveals Shieldin as a Key Regulator of NHEJ and PARP Inhibitor Sensitivity
Rajat Gupta, Kumar Somyajit, Takeo Narita, Elina Maskey, Andre Stanlie, Magdalena Kremer, Dimitris Typas, Michael Lammers, Niels Mailand, Andre Nussenzweig, Jiri Lukas, Chunaram Choudhary
Cell. Author manuscript; available in PMC 2021 May 10.
Published in final edited form as: Cell. 2018 May 3; 173(4): 972–988.e23. Published online 2018 Apr 12. doi: 10.1016/j.cell.2018.03.050
PMCID:
PMC8108093
AbstractArticlePDF–3.5M
11.
A novel p53 regulator, C16ORF72/TAPR1, buffers against telomerase inhibition
Yahya Benslimane, María Sánchez‐Osuna, Jasmin Coulombe‐Huntington, Thierry Bertomeu, Danielle Henry, Caroline Huard, Éric Bonneil, Pierre Thibault, Mike Tyers, Lea Harrington
Aging Cell. 2021 Apr; 20(4): e13331. Published online 2021 Mar 4. doi: 10.1111/acel.13331
PMCID:
PMC8045932
AbstractArticlePDF–1.9M
12.
Active and Passive Destabilization of G-Quadruplex DNA by the Telomere POT1-TPP1 Complex
Mengyuan Xu, Armend Axhemi, Magdalena Malgowska, Yinghua Chen, Daniel Leonard, Sukanya Srinivasan, Eckhard Jankowsky, Derek J. Taylor
J Mol Biol. Author manuscript; available in PMC 2022 Apr 2.
Published in final edited form as: J Mol Biol. 2021 Apr 2; 433(7): 166846. Published online 2021 Feb 4. doi: 10.1016/j.jmb.2021.166846
PMCID:
PMC8020995
AbstractArticlePDF–867K
13.
A Role for Human DNA Polymerase λ in Alternative Lengthening of Telomeres
Elisa Mentegari, Federica Bertoletti, Miroslava Kissova, Elisa Zucca, Silvia Galli, Giulia Tagliavini, Anna Garbelli, Antonio Maffia, Silvia Bione, Elena Ferrari, Fabrizio d’Adda di Fagagna, Sofia Francia, Simone Sabbioneda, Liuh-Yow Chen, Joachim Lingner, Valerie Bergoglio, Jean-Sébastien Hoffmann, Ulrich Hübscher, Emmanuele Crespan, Giovanni Maga
Int J Mol Sci. 2021 Mar; 22(5): 2365. Published online 2021 Feb 27. doi: 10.3390/ijms22052365
PMCID:
PMC7956399
AbstractArticlePDF–4.9M
14.
Identification and characterization of novel ACD variants: modulation of TPP1 protein level offsets the impact of germline loss-of-function variants on telomere length
Gabrielle Henslee, Christopher L. Williams, Pengfei Liu, Alison A. Bertuch
Cold Spring Harb Mol Case Stud. 2021 Feb; 7(1): a005454. doi: 10.1101/mcs.a005454
PMCID:
PMC7903889
AbstractArticlePDF–9.5M
15.
Telomere length set point regulation in human pluripotent stem cells critically depends on the shelterin protein TPP1
John M. Boyle, Kelsey M. Hennick, Samuel G. Regalado, Jacob M. Vogan, Xiaozhu Zhang, Kathleen Collins, Dirk Hockemeyer
Mol Biol Cell. 2020 Nov 1; 31(23): 2583–2596. doi: 10.1091/mbc.E19-08-0447
PMCID:
PMC7851873
AbstractArticlePDF–2.7M
16.
Structural basis of human telomerase recruitment by TPP1-POT1
Zala Sekne, George E. Ghanim, Anne-Marie M. van Roon, Thi Hoang Duong Nguyen
Science. Author manuscript; available in PMC 2022 Apr 11.
Published in final edited form as: Science. 2022 Mar 11; 375(6585): 1173–1176. Published online 2022 Feb 24. doi: 10.1126/science.abn6840
PMCID:
PMC7612489
AbstractArticlePDF–1.7M
17.
A reference map of the human binary protein interactome
Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood
Nature. Author manuscript; available in PMC 2020 Oct 8.
Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x
PMCID:
PMC7169983
AbstractArticlePDF–5.4M
18.
Long interspersed element-1 ribonucleoprotein particles protect telomeric ends in alternative lengthening of telomeres dependent cells
Thomas Aschacher, Brigitte Wolf, Olivia Aschacher, Florian Enzmann, Viktoria Laszlo, Barbara Messner, Adrian Türkcan, Serge Weis, Sabine Spiegl-Kreinecker, Klaus Holzmann, Günther Laufer, Marek Ehrlich, Michael Bergmann
Neoplasia. 2020 Feb; 22(2): 61–75. Published online 2019 Dec 14. doi: 10.1016/j.neo.2019.11.002
PMCID:
PMC6920197
AbstractArticlePDF–3.6M
19.
POT1-TPP1 differentially regulates telomerase via POT1 His266 and as a function of single-stranded telomere DNA length
Mengyuan Xu, Janna Kiselar, Tawna L. Whited, Wilnelly Hernandez-Sanchez, Derek J. Taylor
Proc Natl Acad Sci U S A. 2019 Nov 19; 116(47): 23527–23533. Published online 2019 Nov 4. doi: 10.1073/pnas.1905381116
PMCID:
PMC6876245
AbstractArticlePDF–1023K
20.
TIN2 Functions with TPP1/POT1 To Stimulate Telomerase Processivity
Alexandra M. Pike, Margaret A. Strong, John Paul T. Ouyang, Carol W. Greider
Mol Cell Biol. 2019 Nov 1; 39(21): e00593-18. Prepublished online 2019 Aug 5. Published online 2019 Oct 11. doi: 10.1128/MCB.00593-18
PMCID:
PMC6791651
AbstractArticlePDF–2.0M

Display Settings:

Format
Items per page
Sort by

Send to:

Choose Destination

Supplemental Content

Filter your results:

Find related data

Recent activity

Clear Turn Off Turn On

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

See more...
You are here: NCBI > Literature > PubMed Central (PMC)
Support Center