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Select item 111597481.

Association of genetic polymorphisms in SLCO1B3 and ABCC2 with docetaxel‐induced leukopenia

Kazuma Kiyotani, Taisei Mushiroda, Michiaki Kubo, Hitoshi Zembutsu, Yuichi Sugiyama, Yusuke Nakamura

Cancer Sci. 2008 May; 99(5): 967–972. Published online 2008 Feb 20. doi: 10.1111/j.1349-7006.2008.00765.x

PMCID:: PMC11159748

Abstract Article PDF–101K

Select item 105826632.

Tacrolimus pharmacokinetics are influenced by CYP3A5, age, and concomitant fluconazole in pediatric kidney transplant patients

Alaa Alghamdi, Sarah Seay, David K. Hooper, Charles D. Varnell, Jr., Leanna Darland, Tomoyuki Mizuno, Danielle Lazear, Laura B. Ramsey

Clin Transl Sci. 2023 Oct; 16(10): 1768–1778. Published online 2023 Jun 26. doi: 10.1111/cts.13571

PMCID:: PMC10582663

Abstract Article PDF–3.6M

Select item 105237003.

Association between CYP3A4/CYP3A5 genetic polymorphisms and treatment outcomes of atorvastatin worldwide: is there enough research on the Egyptian population?

Mohammed G. Maslub, Mahasen A. Radwan, Nur Aizati Athirah Daud, Abubakar Sha’aban

Eur J Med Res. 2023; 28: 381. Published online 2023 Sep 27. doi: 10.1186/s40001-023-01038-1

PMCID:: PMC10523700

Abstract Article PDF–1.4M

Select item 103273964.

The impact of ABCB1, CYP3A4/5 and ABCG2 gene polymorphisms on rivaroxaban trough concentrations and bleeding events in patients with non-valvular atrial fibrillation

Tingting Wu, Shuyi Wu, Li Li, Jing Xiang, Na Wang, Wenjun Chen, Jinhua Zhang

Hum Genomics. 2023; 17: 59. Published online 2023 Jul 7. doi: 10.1186/s40246-023-00506-3

PMCID:: PMC10327396

Abstract Article PDF–729K

Select item 101490355.

Pharmacokinetics of the new proton pump inhibitor ilaprazole in Chinese healthy subjects in relation to CYP3A5 and CYP2C19 genotypes

Yalin Li, Wei Zhang, Dong Guo, Gan Zhou, Honghao Zhou, Zhousheng Xiao

Clin Chim Acta. Author manuscript; available in PMC 2023 Apr 30.

Published in final edited form as: Clin Chim Acta. 2008 May; 391(1-2): 60–67. Published online 2008 Feb 14. doi: 10.1016/j.cca.2008.02.003

PMCID:: PMC10149035

Abstract Article PDF–913K

Select item 99332786.

Pharmacogenetics in critical care: association between CYP3A5 rs776746 A/G genotype and acetaminophen response in sepsis and septic shock

C. Scorcella, R. Domizi, S. Amoroso, A. Carsetti, E. Casarotta, P. Castaldo, C. D’angelo, E. Damiani, F. Gasparri, A. Donati, E. Adrario

BMC Anesthesiol. 2023; 23: 55. Published online 2023 Feb 16. doi: 10.1186/s12871-023-02018-y

PMCID:: PMC9933278

Abstract Article PDF–966K

Select item 98066727.

Evaluating the Impacts of CYP3A4*1B and CYP3A5*3 Variations on Pharmacokinetic Behavior and Clinical Outcomes in Multiple Myeloma Patients With Autologous Stem Cell Transplant

JUNAN LI, YU KYOUNG CHO, DOUGLAS W. SBOROV, MITCH A. PHELPS, CRAIG C. HOFMEISTER, MING J. POI

Cancer Genomics Proteomics. 2023 Jan-Feb; 20(1): 9–17. Published online 2023 Jan 3. doi: 10.21873/cgp.20360

PMCID:: PMC9806672

Abstract Article PDF–400K

Select item 96524388.

Regulatory variants in a novel distal enhancer regulate the expression of CYP3A4 and CYP3A5

Joseph M. Collins, Adaeze C. Nworu, Somayya J. Mohammad, Liang Li, Chengcheng Li, Chuanjiang Li, Ethan Schwendeman, Mattew Cefalu, Mahmoud Abdel‐Rasoul, Jessie W. Sun, Sakima A. Smith, Danxin Wang

Clin Transl Sci. 2022 Nov; 15(11): 2720–2731. Published online 2022 Sep 20. doi: 10.1111/cts.13398

PMCID:: PMC9652438

Abstract Article PDF–1.0M

Select item 94961099.

Functional and Structural Impact of Deleterious Missense Single Nucleotide Polymorphisms in the NR3C1, CYP3A5, and TNF-α Genes: An In Silico Analysis

Navakanth Raju Ramayanam, Ranjani Manickam, Vijayakumar Thangavel Mahalingam, Khang Wen Goh, Chrismawan Ardianto, Poovi Ganesan, Long Chiau Ming, Rajanandh Muhasaparur Ganesan

Biomolecules. 2022 Sep; 12(9): 1307. Published online 2022 Sep 16. doi: 10.3390/biom12091307

PMCID:: PMC9496109

Abstract Article PDF–8.9M

Select item 924914910.

Evaluation of genetic polymorphism of CYP3A5 in normal healthy participants from western India - A cross-sectional study

Miteshkumar Rajaram Maurya, Sunanda Gautam, Jeffrey Pradeep Raj, Shruti Saha, Sanchita Ambre, Aishwarya Thakurdesai, Aditya Shah, Urmila Mukund Thatte

Indian J Pharmacol. 2022 Mar-Apr; 54(2): 97–101. Published online 2022 May 10. doi: 10.4103/ijp.ijp_279_21

PMCID:: PMC9249149

Abstract Article

Select item 903631311.

Efavirenz Induces CYP2B6-Mediated Hydroxylation of Bupropion in Healthy Subjects

Sarah M. Robertson, Frank Maldarelli, Ven Natarajan, Elizabeth Formentini, Raul M. Alfaro, Scott R. Penzak

J Acquir Immune Defic Syndr. Author manuscript; available in PMC 2022 Apr 25.

Published in final edited form as: J Acquir Immune Defic Syndr. 2008 Dec 15; 49(5): 513–519. doi: 10.1097/QAI.0b013e318183a425

PMCID:: PMC9036313

Abstract Article PDF–472K

Select item 857819812.

Regulation of CYP3A4 and CYP3A5 by a lncRNA: a potential underlying mechanism explaining the association between CYP3A4*1G and CYP3A metabolism

Joseph M Collins, Danxin Wang

Pharmacogenet Genomics. Author manuscript; available in PMC 2023 Jan 1.

Published in final edited form as: Pharmacogenet Genomics. 2022 Jan 1; 32(1): 16–23. doi: 10.1097/FPC.0000000000000447

PMCID:: PMC8578198

Abstract Article PDF–595K

Select item 853587213.

Could Cytochrome P450 2D6, 3A4 and 3A5 Polymorphisms Explain the Variability in Clinical Response to Clomiphene Citrate of Anovulatory PCOS Women?

Camille Robin, Benjamin Hennart, Franck Broly, Philippine Gruchala, Geoffroy Robin, Sophie Catteau-Jonard

Front Endocrinol (Lausanne) 2021; 12: 718917. Published online 2021 Oct 8. doi: 10.3389/fendo.2021.718917

PMCID:: PMC8535872

Abstract Article PDF–404K

Select item 851633514.

The CYP3A5 genotypes of both liver transplant recipients and donors influence the time‐dependent recovery of tacrolimus clearance during the early stage following transplantation

Li Huang, Abdullah A. Assiri, Peihao Wen, Kun Zhang, Junwei Fan, Tonghai Xing, Yuan Liu, Jinyan Zhang, Zhaowen Wang, Zhaojie Su, Jiajia Chen, Yi Xiao, Rui Wang, Risi Na, Liyun Yuan, Dehua Liu, Junjie Xia, Lin Zhong, Wanqing Liu, Wenzhi Guo, Brian R. Overholser, Zhihai Peng

Clin Transl Med. 2021 Oct; 11(10): e542. Published online 2021 Oct 14. doi: 10.1002/ctm2.542

PMCID:: PMC8516335

Article PDF–1.3M

Select item 851349315.

Genome wide association study identifies the common variants in CYP3A4 and CYP3A5 responsible for variation in tacrolimus trough concentration in Caucasian kidney transplant recipients

William S. Oetting, Baolin Wu, David P. Schladt, Weihua Guan, Rory P. Remmel, Roslyn B. Mannon, Arthur J. Matas, Ajay K. Israni, DeKAF Genomics Investigators

Pharmacogenomics J. Author manuscript; available in PMC 2021 Oct 13.

Published in final edited form as: Pharmacogenomics J. 2018 May 22; 18(3): 501–505. Published online 2017 Nov 21. doi: 10.1038/tpj.2017.49

PMCID:: PMC8513493

Abstract Article PDF–194K

Select item 816503016.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 812873217.

The influence of recipient SLCO1B1 rs2291075 polymorphism on tacrolimus dose–corrected trough concentration in the early period after liver transplantation

Yi Wu, Fang Fang, Zhaowen Wang, Peihao Wen, Junwei Fan

Eur J Clin Pharmacol. 2021; 77(6): 859–867. Published online 2021 Jan 2. doi: 10.1007/s00228-020-03058-w

PMCID:: PMC8128732

Abstract Article PDF–385K

Select item 806209318.

The impact of cytochrome P450 3A genetic polymorphisms on tacrolimus pharmacokinetics in ulcerative colitis patients

Maizumi Furuse, Shuhei Hosomi, Yu Nishida, Shigehiro Itani, Yuji Nadatani, Shusei Fukunaga, Koji Otani, Fumio Tanaka, Yasuaki Nagami, Koichi Taira, Noriko Kamata, Toshio Watanabe, Kenji Watanabe, Yasuhiro Fujiwara

PLoS One. 2021; 16(4): e0250597. Published online 2021 Apr 22. doi: 10.1371/journal.pone.0250597

PMCID:: PMC8062093

Abstract Article PDF–787K

Select item 800948219.

CYP3A5 genotype affects time to therapeutic tacrolimus level in pediatric kidney transplant recipients

Megan V. Yanik, Michael E. Seifert, Jayme E. Locke, Vera Hauptfeld-Dolejsek, Michael R. Crowley, Gary R. Cutter, Roslyn B. Mannon, Daniel I. Feig, Nita A. Limdi

Pediatr Transplant. Author manuscript; available in PMC 2021 Mar 30.

Published in final edited form as: Pediatr Transplant. 2019 Aug; 23(5): e13494. Published online 2019 May 24. doi: 10.1111/petr.13494

PMCID:: PMC8009482

Abstract Article PDF–694K

Select item 756688120.

Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism

Michael Aregger, Keith A. Lawson, Maximillian Billmann, Michael Costanzo, Amy H. Y. Tong, Katherine Chan, Mahfuzur Rahman, Kevin R. Brown, Catherine Ross, Matej Usaj, Lucy Nedyalkova, Olga Sizova, Andrea Habsid, Judy Pawling, Zhen-Yuan Lin, Hala Abdouni, Cassandra J. Wong, Alexander Weiss, Patricia Mero, James W. Dennis, Anne-Claude Gingras, Chad L. Myers, Brenda J. Andrews, Charles Boone, Jason Moffat

Nat Metab. Author manuscript; available in PMC 2020 Dec 1.

Published in final edited form as: Nat Metab. 2020 Jun; 2(6): 499–513. Published online 2020 Jun 1. doi: 10.1038/s42255-020-0211-z

PMCID:: PMC7566881

Abstract Article PDF–4.8M

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