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Items: 1 to 20 of 79

1.
Establishment of an immortalized cell line from a precancerous lesion of lung adenocarcinoma, and genes highly expressed in the early stages of lung adenocarcinoma development
Aki Shimada, Junko Kano, Tadashi Ishiyama, Chigusa Okubo, Tatsuo Iijima, Yukio Morishita, Yuko Minami, Yukinori Inadome, Yujian Shu, Shintaro Sugita, Tomoyo Takeuchi, Masayuki Noguchi
Cancer Sci. 2005 Oct; 96(10): 668–675. Published online 2005 Sep 1. doi: 10.1111/j.1349-7006.2005.00100.x
PMCID:
PMC11159238
AbstractArticlePDF–323K
2.
Diagnostic and prognostic utility of TROP-2, SLP-2, and CXCL12 expression in papillary thyroid carcinoma
Amany Selim Attia, Samia Hussein, Hend Sameh, Amr Khalil, Ahmad Barakat Waley, Ihab Matar, Reham Sameh
Cancer Biomark. 2024; 39(3): 211–221. Prepublished online 2023 Nov 23. Published online 2024 Mar 14. doi: 10.3233/CBM-230230
PMCID:
PMC11091596
AbstractArticlePDF–3.0M
3.
TROP2 Is Associated with Primary Resistance to Immune Checkpoint Inhibition in Patients with Advanced Non–Small Cell Lung Cancer
Alban Bessede, Florent Peyraud, Benjamin Besse, Sophie Cousin, Mathilde Cabart, François Chomy, Christophe Rey, Oren Lara, Ophélie Odin, Imane Nafia, Lucile Vanhersecke, Fabrice Barlesi, Jean-Philippe Guégan, Antoine Italiano
Clin Cancer Res. 2024 Feb 16; 30(4): 779–785. Published online 2023 Dec 4. doi: 10.1158/1078-0432.CCR-23-2566
PMCID:
PMC10870116
AbstractArticlePDF–3.5M
4.
DNA demethylation and tri-methylation of H3K4 at the TACSTD2 promoter are complementary players for TROP2 regulation in colorectal cancer cells
A. Gehring, K. Huebner, H. Rani, K. Erlenbach-Wuensch, S. Merkel, V. Mahadevan, R. Grutzmann, A. Hartmann, R. Schneider-Stock
Sci Rep. 2024; 14: 2683. Published online 2024 Feb 1. doi: 10.1038/s41598-024-52437-1
PMCID:
PMC10834991
AbstractArticlePDF–2.3M
5.
Trophoblast cell surface antigen-2 phosphorylation triggered by binding of galectin-3 drives metastasis through down-regulation of E-cadherin
Shungo Iwamoto, Yugo Mori, Tomoko Yamashita, Kazuki Ojima, Kaoru Akita, Shingo Togano, Shuhei Kushiyama, Masakazu Yashiro, Yuki Yatera, Tomoko Yamaguchi, Akane Komiyama, Yuki Sago, Naoki Itano, Hiroshi Nakada
J Biol Chem. 2023 Aug; 299(8): 104971. Published online 2023 Jun 27. doi: 10.1016/j.jbc.2023.104971
PMCID:
PMC10392139
AbstractArticlePDF–6.6M
6.
TROP-2 is widely expressed in vulvar squamous cell carcinoma and represents a potential new therapeutic target
Mateja Condic, Eva K. Egger, Niklas Klümper, Glen Kristiansen, Alexander Mustea, Thore Thiesler, Damian J. Ralser
J Cancer Res Clin Oncol. 2023; 149(11): 8235–8241. Published online 2023 Apr 17. doi: 10.1007/s00432-023-04761-8
PMCID:
PMC10374825
AbstractArticlePDF–1.3M
7.
Trop-2 and Nectin-4 immunohistochemical expression in metastatic colorectal cancer: searching for the right population for drugs’ development
Roberto Moretto, Marco Maria Germani, Mirella Giordano, Veronica Conca, Agnese Proietti, Cristina Niccoli, Filippo Pietrantonio, Sara Lonardi, Emiliano Tamburini, Alberto Zaniboni, Alessandro Passardi, Tiziana Pia Latiano, Valentina Fanotto, Samantha Di Donato, Michele Prisciandaro, Francesca Bergamo, Gianluca Masi, Gabriella Fontanini, Clara Ugolini, Chiara Cremolini
Br J Cancer. 2023 Mar 30; 128(7): 1391–1399. Published online 2023 Feb 9. doi: 10.1038/s41416-023-02180-7
PMCID:
PMC10049995
AbstractArticlePDF–582K
8.
Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma
Yu-Fei Cao, Lei Xie, Bei-Bei Tong, Man-Yu Chu, Wen-Qi Shi, Xiang Li, Jian-Zhong He, Shao-Hong Wang, Zhi-Yong Wu, Dan-Xia Deng, Ya-Qi Zheng, Zhi-Mao Li, Xiu-E Xu, Lian-Di Liao, Yin-Wei Cheng, Li-Yan Li, Li-Yan Xu, En-Min Li
Cell Death Differ. 2023 Feb; 30(2): 527–543. Published online 2022 Dec 16. doi: 10.1038/s41418-022-01104-x
PMCID:
PMC9950447
AbstractArticlePDF–8.4M
9.
Alteration of Trop-2 expression in breast cancer cells by clinically used therapeutic agents and acquired tamoxifen resistance
Jing Zhu, Wenwen Wu, Yukiko Togashi, Naoe Taira Nihira, Yoshikazu Johmura, Dajiang Zhu, Makoto Nakanishi, Yasuo Miyoshi, Tomohiko Ohta
Breast Cancer. 2022; 29(6): 1076–1087. Published online 2022 Jul 27. doi: 10.1007/s12282-022-01389-3
PMCID:
PMC9587948
AbstractArticlePDF–2.2M
10.
Trophoblast cell-surface antigen 2 (TROP2) expression in triple-negative breast cancer
Yeonjin Jeon, Uiree Jo, Jongmoo Hong, Gyungyub Gong, Hee Jin Lee
BMC Cancer. 2022; 22: 1014. Published online 2022 Sep 24. doi: 10.1186/s12885-022-10076-7
PMCID:
PMC9509625
AbstractArticlePDF–1.1M
11.
ATF2 loss promotes tumor invasion in colorectal cancer cells via upregulation of cancer driver TROP2
Kerstin Huebner, Katharina Erlenbach-Wuensch, Jan Prochazka, Ilir Sheraj, Chuanpit Hampel, Blanka Mrazkova, Tereza Michalcikova, Jolana Tureckova, Veronika Iatsiuk, Anne Weissmann, Fulvia Ferrazzi, Philipp Kunze, Enise Nalli, Elisabeth Sammer, Annemarie Gehring, Marie M. Cheema, Markus Eckstein, Eva-Maria Paap, Agnes Soederberg, Corinna Fischer, Sushmita Paul, Vijayalakshmi Mahadevan, Benardina Ndreshkjana, Melanie A. Meier, Susanne Muehlich, Carol I. Geppert, Susanne Merkel, Robert Grutzmann, Adriana Roehe, Sreeparna Banerjee, Arndt Hartmann, Radislav Sedlacek, Regine Schneider-Stock
Cell Mol Life Sci. 2022 Aug; 79(8): 423. Published online 2022 Jul 15. doi: 10.1007/s00018-022-04445-5
PMCID:
PMC9287261
AbstractArticlePDF–3.6M
12.
Scalable multiplex co-fractionation/mass spectrometry platform for accelerated protein interactome discovery
Pierre C. Havugimana, Raghuveera Kumar Goel, Sadhna Phanse, Ahmed Youssef, Dzmitry Padhorny, Sergei Kotelnikov, Dima Kozakov, Andrew Emili
Nat Commun. 2022; 13: 4043. Published online 2022 Jul 13. doi: 10.1038/s41467-022-31809-z
PMCID:
PMC9279285
AbstractArticlePDF–2.5M
13.
Impact of Spatially Heterogeneous Trop-2 Expression on Prognosis in Oral Squamous Cell Carcinoma
Ramona Erber, Steffen Spoerl, Andreas Mamilos, Rosemarie Krupar, Arndt Hartmann, Matthias Ruebner, Juergen Taxis, Mareike Wittenberg, Torsten E. Reichert, Gerrit Spanier, Silvia Spoerl
Int J Mol Sci. 2022 Jan; 23(1): 87. Published online 2021 Dec 22. doi: 10.3390/ijms23010087
PMCID:
PMC8745008
AbstractArticlePDF–29M
14.
Competitive binding of E3 ligases TRIM26 and WWP2 controls SOX2 in glioblastoma
Tatenda Mahlokozera, Bhuvic Patel, Hao Chen, Patrick Desouza, Xuan Qu, Diane D. Mao, Daniel Hafez, Wei Yang, Rukayat Taiwo, Mounica Paturu, Afshin Salehi, Amit D. Gujar, Gavin P. Dunn, Nima Mosammaparast, Allegra A. Petti, Hiroko Yano, Albert H. Kim
Nat Commun. 2021; 12: 6321. Published online 2021 Nov 3. doi: 10.1038/s41467-021-26653-6
PMCID:
PMC8566473
AbstractArticlePDF–2.7M
15.
Trop-2 induces ADAM10-mediated cleavage of E-cadherin and drives EMT-less metastasis in colon cancer
Emanuela Guerra, Marco Trerotola, Valeria Relli, Rossano Lattanzio, Romina Tripaldi, Giovanna Vacca, Martina Ceci, Khouloud Boujnah, Valeria Garbo, Antonino Moschella, Romina Zappacosta, Pasquale Simeone, Robert de Lange, Ulrich H. Weidle, Maria Teresa Rotelli, Arcangelo Picciariello, Raffaella Depalo, Patrizia Querzoli, Massimo Pedriali, Enzo Bianchini, Domenico Angelucci, Giuseppe Pizzicannella, Carla Di Loreto, Mauro Piantelli, Laura Antolini, Xiao-Feng Sun, Donato F. Altomare, Saverio Alberti
Neoplasia. 2021 Sep; 23(9): 898–911. Published online 2021 Jul 25. doi: 10.1016/j.neo.2021.07.002
PMCID:
PMC8334386
AbstractArticlePDF–4.7M
16.
Trop2 Expression in Extramammary Paget’s Disease and Normal Skin
Takamichi Ito, Keiko Tanegashima, Yuka Tanaka, Hiroki Hashimoto, Maho Murata, Yoshinao Oda, Yumiko Kaku-Ito
Int J Mol Sci. 2021 Jul; 22(14): 7706. Published online 2021 Jul 19. doi: 10.3390/ijms22147706
PMCID:
PMC8304908
AbstractArticlePDF–4.7M
17.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
18.
DNA methylation of tumor associated calcium signal transducer 2 (TACSTD2) loci shows association with clinically aggressive renal cell cancers
Olga Katzendorn, Inga Peters, Natalia Dubrowinskaja, Hossein Tezval, Pouriya Faraj Tabrizi, Christoph A. von Klot, Jörg Hennenlotter, Marcel Lafos, Markus A. Kuczyk, Jürgen Serth
BMC Cancer. 2021; 21: 444. Published online 2021 Apr 21. doi: 10.1186/s12885-021-08172-1
PMCID:
PMC8061065
AbstractArticlePDF–926K
19.
Trop‐2 cleavage by ADAM10 is an activator switch for cancer growth and metastasis
Marco Trerotola, Emanuela Guerra, Zeeshan Ali, Anna Laura Aloisi, Martina Ceci, Pasquale Simeone, Angela Acciarito, Paola Zanna, Giovanna Vacca, Antonella D'Amore, Khouloud Boujnah, Valeria Garbo, Antonino Moschella, Rossano Lattanzio, Saverio Alberti
Neoplasia. 2021 Apr; 23(4): 415–428. Published online 2021 Apr 8. doi: 10.1016/j.neo.2021.03.006
PMCID:
PMC8042651
AbstractArticlePDF–3.1M
20.
Trop2 is Upregulated in the Transition to Dysplasia in the Metaplastic Gastric Mucosa
Katherine M. Riera, Bogun Jang, Jimin Min, Joseph T. Roland, Qing Yang, William T. Fesmire, Sophie Camilleri-Broet, Lorenzo Ferri, Woo Ho Kim, Eunyoung Choi, James R. Goldenring
J Pathol. Author manuscript; available in PMC 2021 Mar 31.
Published in final edited form as: J Pathol. 2020 Jul; 251(3): 336–347. Published online 2020 Jun 15. doi: 10.1002/path.5469
PMCID:
PMC8010636
AbstractArticlePDF–2.4M

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