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Select item 96228711.

Drug transporters OAT1 and OAT3 have specific effects on multiple organs and gut microbiome as revealed by contextualized metabolic network reconstructions

Neema Jamshidi, Sanjay K. Nigam

Sci Rep. 2022; 12: 18308. Published online 2022 Oct 31. doi: 10.1038/s41598-022-21091-w

PMCID:: PMC9622871

Abstract Article PDF–6.0M

Select item 89978292.

Functional Characterization of Rare Variants in OAT1/SLC22A6 and OAT3/SLC22A8 Urate Transporters Identified in a Gout and Hyperuricemia Cohort

Jiří Vávra, Andrea Mančíková, Kateřina Pavelcová, Lenka Hasíková, Jana Bohatá, Blanka Stibůrková

Cells. 2022 Apr; 11(7): 1063. Published online 2022 Mar 22. doi: 10.3390/cells11071063

PMCID:: PMC8997829

Abstract Article PDF–1.6M

Select item 87489583.

EZH2 depletion potentiates MYC degradation inhibiting neuroblastoma and small cell carcinoma tumor formation

Liyuan Wang, Chan Chen, Zemin Song, Honghong Wang, Minghui Ye, Donghai Wang, Wenqian Kang, Hudan Liu, Guoliang Qing

Nat Commun. 2022; 13: 12. Published online 2022 Jan 10. doi: 10.1038/s41467-021-27609-6

PMCID:: PMC8748958

Abstract Article PDF–3.0M

Select item 81650304.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 78646765.

The Activity of Organic Anion Transporter-3: Role of Dexamethasone

Haoxun Wang, Chenchang Liu, Guofeng You

J Pharmacol Sci. Author manuscript; available in PMC 2021 Feb 5.

Published in final edited form as: J Pharmacol Sci. 2018 Feb; 136(2): 79–85. Published online 2018 Feb 2. doi: 10.1016/j.jphs.2017.12.011

PMCID:: PMC7864676

Abstract Article PDF–1.1M

Select item 66478576.

Activation of Protein Kinase A stimulates SUMOylation, expression, and transport activity of Organic Anion Transporter 3

Haoxun Wang, Jinghui Zhang, Guofeng You

AAPS J. Author manuscript; available in PMC 2019 Jul 23.

Published in final edited form as: AAPS J. 2019 Feb 13; 21(2): 30. Published online 2019 Feb 13. doi: 10.1208/s12248-019-0303-4

PMCID:: PMC6647857

Abstract Article PDF–1.1M

Select item 65598247.

The SUMO-Specific Protease Senp2 Regulates SUMOylation, Expression and Function of Human Organic Anion Transporter 3

Haoxun Wang, Guofeng You

Biochim Biophys Acta Biomembr. Author manuscript; available in PMC 2020 Jul 1.

Published in final edited form as: Biochim Biophys Acta Biomembr. 2019 Jul 1; 1861(7): 1293–1301. Published online 2019 May 1. doi: 10.1016/j.bbamem.2019.04.007

PMCID:: PMC6559824

Abstract Article PDF–1.1M

Select item 61666828.

Histone Interaction Landscapes Visualized by Crosslinking Mass Spectrometry in Intact Cell Nuclei

Domenico Fasci, Hugo van Ingen, Richard A. Scheltema, Albert J. R. Heck

Mol Cell Proteomics. 2018 Oct; 17(10): 2018–2033. Published online 2018 Jul 18. doi: 10.1074/mcp.RA118.000924

PMCID:: PMC6166682

Abstract Article PDF–3.8M

Select item 59842529.

Population specific resequencing associates the ATP Binding Cassette Subfamily C Member 4 (ABCC4) gene with gout in New Zealand Maori and Pacific men

Callum Tanner, James Boocock, Eli A Stahl, Amanda Dobbyn, Asim K Mandal, Murray Cadzow, Amanda J Phipps-Green, Ruth K Topless, Jennie Harré Hindmarsh, Lisa K Stamp, Nicola Dalbeth, Hyon K Choi, David B Mount, Tony R Merriman

Arthritis Rheumatol. Author manuscript; available in PMC 2018 Jul 1.

Published in final edited form as: Arthritis Rheumatol. 2017 Jul; 69(7): 1461–1469. Published online 2017 May 31. doi: 10.1002/art.40110

PMCID:: PMC5984252

Abstract Article PDF–554K

Select item 566817310.

SGK1/Nedd4-2 signaling pathway regulates the activity of Human Organic Anion Transporters 3

Haoxun Wang, Guofeng You

Biopharm Drug Dispos. Author manuscript; available in PMC 2018 Nov 1.

Published in final edited form as: Biopharm Drug Dispos. 2017 Nov; 38(8): 449–457. Published online 2017 Aug 22. doi: 10.1002/bdd.2085

PMCID:: PMC5668173

Abstract Article PDF–750K

Select item 563234711.

Organic anion transporters, OAT1 and OAT3, are crucial biopterin transporters involved in bodily distribution of tetrahydrobiopterin and exclusion of its excess

Akiko Ohashi, Kaori Mamada, Tomonori Harada, Masako Naito, Tomihisa Takahashi, Shin Aizawa, Hiroyuki Hasegawa

Mol Cell Biochem. 2017; 435(1): 97–108. Published online 2017 May 22. doi: 10.1007/s11010-017-3060-7

PMCID:: PMC5632347

Abstract Article PDF–548K

Select item 517527312.

An Essential Role of Nedd4-2 in the Ubiquitination, Expression and Function of Organic Anion Transporter-3

Da Xu, Haoxun Wang, Guofeng You

Mol Pharm. Author manuscript; available in PMC 2017 Feb 1.

Published in final edited form as: Mol Pharm. 2016 Feb 1; 13(2): 621–630. Published online 2015 Dec 22. doi: 10.1021/acs.molpharmaceut.5b00839

PMCID:: PMC5175273

Abstract Article PDF–943K

Select item 465582213.

Establishment and Dysfunction of the Blood-Brain Barrier

Zhen Zhao, Amy R. Nelson, Christer Betsholtz, Berislav V. Zlokovic

Cell. Author manuscript; available in PMC 2016 Nov 19.

Published in final edited form as: Cell. 2015 Nov 19; 163(5): 1064–1078. doi: 10.1016/j.cell.2015.10.067

PMCID:: PMC4655822

Abstract Article PDF–1.4M

Select item 441735914.

Impact of Organic Anion Transporter 3 (OAT3) on renal transport of the metal chelator 2,3-Dimercapto-1-propane-sulfonate (DMPS)

Matthias Rödiger, Xiaohong Zhang, Bernhard Ugele, Nikolaus Gersdorff, Stephen H. Wright, Gerhard Burckhardt, Andrew Bahn

Can J Physiol Pharmacol. Author manuscript; available in PMC 2015 May 2.

Published in final edited form as: Can J Physiol Pharmacol. 2010 Feb; 88(2): 141–146. doi: 10.1139/Y09-123

PMCID:: PMC4417359

Abstract Article PDF–1.2M

Select item 415124615.

Reduced Renal Clearance of Cefotaxime in Asians with a Low-Frequency Polymorphism of OAT3 (SLC22A8)

Sook Wah Yee, Anh Nguyet Nguyen, Chaline Brown, Radojka M. Savic, Youcai Zhang, Richard A. Castro, Cheryl D. Cropp, Ji Ha Choi, Diment Singh, Harunobu Tahara, Sophie L. Stocker, Yong Huang, Claire M. Brett, Kathleen M. Giacomini

J Pharm Sci. Author manuscript; available in PMC 2014 Sep 2.

Published in final edited form as: J Pharm Sci. 2013 Sep; 102(9): 3451–3457. Published online 2013 May 6. doi: 10.1002/jps.23581

PMCID:: PMC4151246

Abstract Article PDF–2.4M

Select item 401682016.

Angiotensin II inhibits activity of human organic anion transporter 3 through activation of protein kinase Cα: accelerating endocytosis of the transporter

Peng Duan, Shanshan Li, Guofeng You

Eur J Pharmacol. Author manuscript; available in PMC 2014 May 11.

Published in final edited form as: Eur J Pharmacol. 2010 Feb 10; 627(0): 49–55. Published online 2009 Oct 28. doi: 10.1016/j.ejphar.2009.10.048

PMCID:: PMC4016820

Abstract Article PDF–2.2M

Select item 334973417.

Genome-Wide Association for Abdominal Subcutaneous and Visceral Adipose Reveals a Novel Locus for Visceral Fat in Women

Caroline S. Fox, Yongmei Liu, Charles C. White, Mary Feitosa, Albert V. Smith, Nancy Heard-Costa, Kurt Lohman, GIANT Consortium, MAGIC Consortium, GLGC Consortium, Andrew D. Johnson, Meredith C. Foster, Danielle M. Greenawalt, Paula Griffin, Jinghong Ding, Anne B. Newman, Fran Tylavsky, Iva Miljkovic, Stephen B. Kritchevsky, Lenore Launer, Melissa Garcia, Gudny Eiriksdottir, J. Jeffrey Carr, Vilmunder Gudnason, Tamara B. Harris, L. Adrienne Cupples, Ingrid B. Borecki

PLoS Genet. 2012 May; 8(5): e1002695. Published online 2012 May 10. doi: 10.1371/journal.pgen.1002695