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Select item 110273501.

The histone lysine acetyltransferase KAT2B inhibits cholangiocarcinoma growth: evidence for interaction with SP1 to regulate NF2-YAP signaling

Wenbo Ma, Jinqiang Zhang, Weina Chen, Nianli Liu, Tong Wu

J Exp Clin Cancer Res. 2024; 43: 117. Published online 2024 Apr 19. doi: 10.1186/s13046-024-03036-5

PMCID:: PMC11027350

Abstract Article PDF–4.4M

Select item 109332672.

Interaction network of human early embryonic transcription factors

Lisa Gawriyski, Zenglai Tan, Xiaonan Liu, Iftekhar Chowdhury, Dicle Malaymar Pinar, Qin Zhang, Jere Weltner, Eeva-Mari Jouhilahti, Gong-Hong Wei, Juha Kere, Markku Varjosalo

EMBO Rep. 2024 Mar; 25(3): 1589–1622. Published online 2024 Jan 31. doi: 10.1038/s44319-024-00074-0

PMCID:: PMC10933267

Abstract Article PDF–2.9M

Select item 105918363.

ATAC and SAGA co-activator complexes utilize co-translational assembly, but their cellular localization properties and functions are distinct

Gizem Yayli, Andrea Bernardini, Paulina Karen Mendoza Sanchez, Elisabeth Scheer, Mylène Damilot, Karim Essabri, Bastien Morlet, Luc Negroni, Stéphane D. Vincent, H.T. Marc Timmers, László Tora

Cell Rep. Author manuscript; available in PMC 2023 Oct 23.

Published in final edited form as: Cell Rep. 2023 Sep 26; 42(9): 113099. Published online 2023 Sep 8. doi: 10.1016/j.celrep.2023.113099

PMCID:: PMC10591836

Abstract Article PDF–2.6M

Select item 101826544.

The pattern of histone H3 epigenetic posttranslational modifications is regulated by the VRK1 chromatin kinase

Eva Monte-Serrano, Patricia Morejón-García, Ignacio Campillo-Marcos, Aurora Campos-Díaz, Elena Navarro-Carrasco, Pedro A. Lazo

Epigenetics Chromatin. 2023; 16: 18. Published online 2023 May 13. doi: 10.1186/s13072-023-00494-7

PMCID:: PMC10182654

Abstract Article PDF–3.1M

Select item 101476835.

Dependency of NELF-E-SLUG-KAT2B epigenetic axis in breast cancer carcinogenesis

Jieqiong Zhang, Zhenhua Hu, Hwa Hwa Chung, Yun Tian, Kah Weng Lau, Zheng Ser, Yan Ting Lim, Radoslaw M. Sobota, Hwei Fen Leong, Benjamin Jieming Chen, Clarisse Jingyi Yeo, Shawn Ying Xuan Tan, Jian Kang, Dennis Eng Kiat Tan, Ieng Fong Sou, Urszula Lucja McClurg, Manikandan Lakshmanan, Thamil Selvan Vaiyapuri, Anandhkumar Raju, Esther Sook Miin Wong, Vinay Tergaonkar, Ravisankar Rajarethinam, Elina Pathak, Wai Leong Tam, Ern Yu Tan, Wee-Wei Tee

Nat Commun. 2023; 14: 2439. Published online 2023 Apr 28. doi: 10.1038/s41467-023-38132-1

PMCID:: PMC10147683

Abstract Article PDF–7.7M

Select item 96038916.

Downregulation of P300/CBP-Associated Factor Protects from Vascular Aging via Nrf2 Signal Pathway Activation

Liqiang Qiu, Xiaoxiong Liu, Hao Xia, Changwu Xu

Int J Mol Sci. 2022 Oct; 23(20): 12574. Published online 2022 Oct 20. doi: 10.3390/ijms232012574

PMCID:: PMC9603891

Abstract Article PDF–3.0M

Select item 95608187.

PCAF Accelerates Vascular Senescence via the Hippo Signaling Pathway

Chaohua Kong, Dongchen Wang, Feng Wang, Yifei Lv, Wenying Zhou, Peng Ye, Yue Gu, Xiaomin Jiang, Linlin Zhu, Zhen Ge, Yuelin Chao, Shaoliang Chen

Oxid Med Cell Longev. 2022; 2022: 1200602. Published online 2022 Oct 6. doi: 10.1155/2022/1200602

PMCID:: PMC9560818

Abstract Article PDF–6.7M

Select item 95308758.

N4BP3 promotes angiogenesis in hepatocellular carcinoma by binding with KAT2B

Hexu Han, Wei Zhu, Ting Lin, Cuixia Liu, Hengyong Zhai

Cancer Sci. 2022 Oct; 113(10): 3390–3404. Published online 2022 Aug 1. doi: 10.1111/cas.15498

PMCID:: PMC9530875

Abstract Article PDF–14M

Select item 91197369.

OpenCell: proteome-scale endogenous tagging enables the cartography of human cellular organization

Nathan H. Cho, Keith C. Cheveralls, Andreas-David Brunner, Kibeom Kim, André C. Michaelis, Preethi Raghavan, Hirofumi Kobayashi, Laura Savy, Jason Y. Li, Hera Canaj, James Y.S. Kim, Edna M. Stewart, Christian Gnann, Frank McCarthy, Joana P. Cabrera, Rachel M. Brunetti, Bryant B. Chhun, Greg Dingle, Marco Y. Hein, Bo Huang, Shalin B. Mehta, Jonathan S. Weissman, Rafael Gómez-Sjöberg, Daniel N. Itzhak, Loic A. Royer, Matthias Mann, Manuel D. Leonetti

Science. Author manuscript; available in PMC 2022 Sep 11.

Published in final edited form as: Science. 2022 Mar 11; 375(6585): eabi6983. Published online 2022 Mar 11. doi: 10.1126/science.abi6983

PMCID:: PMC9119736

Abstract Article PDF–3.3M

Select item 882889510.

Human transcription factor protein interaction networks

Helka Göös, Matias Kinnunen, Kari Salokas, Zenglai Tan, Xiaonan Liu, Leena Yadav, Qin Zhang, Gong-Hong Wei, Markku Varjosalo

Nat Commun. 2022; 13: 766. Published online 2022 Feb 9. doi: 10.1038/s41467-022-28341-5

PMCID:: PMC8828895

Abstract Article PDF–1.7M

Select item 880681711.

Lysine Acetyltransferase 2B predicts favorable prognosis and functions as anti-oncogene in cervical carcinoma

Lei Li, Juntao Zhang, Shuping Cao

Bioengineered. 2021; 12(1): 2563–2575. Published online 2021 Jun 15. doi: 10.1080/21655979.2021.1935525

PMCID:: PMC8806817

Abstract Article PDF–3.7M

Select item 874895812.

EZH2 depletion potentiates MYC degradation inhibiting neuroblastoma and small cell carcinoma tumor formation

Liyuan Wang, Chan Chen, Zemin Song, Honghong Wang, Minghui Ye, Donghai Wang, Wenqian Kang, Hudan Liu, Guoliang Qing

Nat Commun. 2022; 13: 12. Published online 2022 Jan 10. doi: 10.1038/s41467-021-27609-6

PMCID:: PMC8748958

Abstract Article PDF–3.0M

Select item 863005913.

SIRT1 coordinates with the CRL4B complex to regulate pancreatic cancer stem cells to promote tumorigenesis

Shuai Leng, Wei Huang, Yang Chen, Yang Yang, Dandan Feng, Wei Liu, Tianyang Gao, Yanli Ren, Miaomiao Huo, Jingyao Zhang, Yunkai Yang, Yan Wang

Cell Death Differ. 2021 Dec; 28(12): 3329–3343. Published online 2021 Jun 23. doi: 10.1038/s41418-021-00821-z

PMCID:: PMC8630059

Abstract Article PDF–11M

Select item 862113914.

Interplay between protein acetylation and ubiquitination controls MCL1 protein stability

Kouhei Shimizu, Min Gi, Shugo Suzuki, Brian J. North, Asami Watahiki, Satoshi Fukumoto, John M. Asara, Fuminori Tokunaga, Wenyi Wei, Hiroyuki Inuzuka

Cell Rep. Author manuscript; available in PMC 2021 Nov 26.

Published in final edited form as: Cell Rep. 2021 Nov 9; 37(6): 109988. doi: 10.1016/j.celrep.2021.109988

PMCID:: PMC8621139

Abstract Article PDF–2.0M

Select item 847267715.

P300/CBP-Associated Factor Activates Cardiac Fibroblasts by SMAD2 Acetylation

Yongwoon Lim, Anna Jeong, Duk-Hwa Kwon, Yeong-Un Lee, Young-Kook Kim, Youngkeun Ahn, Taewon Kook, Woo-Jin Park, Hyun Kook

Int J Mol Sci. 2021 Sep; 22(18): 9944. Published online 2021 Sep 14. doi: 10.3390/ijms22189944

PMCID:: PMC8472677

Abstract Article PDF–8.4M

Select item 822189316.

Differential Expression Study of Lysine Crotonylation and Proteome for Chronic Obstructive Pulmonary Disease Combined with Type II Respiratory Failure

Qing Gan, Donge Tang, Qiang Yan, Jiejing Chen, Yong Xu, Wen Xue, Lu Xiao, Fengping Zheng, Huixuan Xu, Yingyun Fu, Yong Dai

Can Respir J. 2021; 2021: 6652297. Published online 2021 Jun 15. doi: 10.1155/2021/6652297

PMCID:: PMC8221893

Abstract Article PDF–505K

Select item 816503017.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 803071718.

In-vitro acetylation of SARS-CoV and SARS-CoV-2 nucleocapsid proteins by human PCAF and GCN5

Dai Hatakeyama, Takeshi Masuda, Ryosuke Miki, Sumio Ohtsuki, Takashi Kuzuhara

Biochem Biophys Res Commun. 2021 Jun 11; 557: 273–279. Published online 2021 Apr 8. doi: 10.1016/j.bbrc.2021.03.173

PMCID:: PMC8030717

Abstract Article PDF–1.9M

Select item 800967819.

Promoter-specific changes in initiation, elongation, and homeostasis of histone H3 acetylation during CBP/p300 inhibition

Emily Hsu, Nathan R Zemke, Arnold J Berk

eLife. 2021; 10: e63512. Published online 2021 Mar 11. doi: 10.7554/eLife.63512

PMCID:: PMC8009678

Abstract Article PDF–2.5M

Select item 791045920.

Combinatorial CRISPR screen identifies fitness effects of gene paralogues

Nicola A. Thompson, Marco Ranzani, Louise van der Weyden, Vivek Iyer, Victoria Offord, Alastair Droop, Fiona Behan, Emanuel Gonçalves, Anneliese Speak, Francesco Iorio, James Hewinson, Victoria Harle, Holly Robertson, Elizabeth Anderson, Beiyuan Fu, Fengtang Yang, Guido Zagnoli-Vieira, Phil Chapman, Martin Del Castillo Velasco-Herrera, Mathew J. Garnett, Stephen P. Jackson, David J. Adams

Nat Commun. 2021; 12: 1302. Published online 2021 Feb 26. doi: 10.1038/s41467-021-21478-9

PMCID:: PMC7910459

Abstract Article PDF–3.3M

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