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Items: 1 to 20 of 38

1.
Recurring EPHB1 mutations in human cancers alter receptor signalling and compartmentalisation of colorectal cancer cells
Snehangshu Kundu, Luís Nunes, Jeremy Adler, Lucy Mathot, Ivaylo Stoimenov, Tobias Sjöblom
Cell Commun Signal. 2023; 21: 354. Published online 2023 Dec 15. doi: 10.1186/s12964-023-01378-9
PMCID:
PMC10722860
AbstractArticlePDF–2.9M
2.
Physical and functional interactome atlas of human receptor tyrosine kinases
Kari Salokas, Xiaonan Liu, Tiina Öhman, Iftekhar Chowdhury, Lisa Gawriyski, Salla Keskitalo, Markku Varjosalo
EMBO Rep. 2022 Jun; 23(6): e54041. Published online 2022 Apr 5. doi: 10.15252/embr.202154041
PMCID:
PMC9171411
AbstractArticlePDF–1.9M
3.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
4.
Identification of tetracycline combinations as EphB1 tyrosine kinase inhibitors for treatment of neuropathic pain
Mahmoud S. Ahmed, Ping Wang, Ngoc Uyen Nhi Nguyen, Yuji Nakada, Ivan Menendez-Montes, Muhammad Ismail, Robert Bachoo, Mark Henkemeyer, Hesham A. Sadek, Enas S. Kandil
Proc Natl Acad Sci U S A. 2021 Mar 9; 118(10): e2016265118. Published online 2021 Feb 24. doi: 10.1073/pnas.2016265118
PMCID:
PMC7958374
AbstractArticlePDF–1.9M
5.
Peripheral EphrinB1/EphB1 signalling attenuates muscle hyperalgesia in MPS patients and a rat model of taut band-associated persistent muscle pain
Feihong Jin, Lianying Zhao, Qiya Hu, Feng Qi
Mol Pain. 2020; 16: 1744806920984079. Published online 2020 Dec 27. doi: 10.1177/1744806920984079
PMCID:
PMC7780166
AbstractArticlePDF–849K
6.
Specification of Distinct Dopaminergic Neural Pathways: Roles of the Eph Family Receptor EphB1 and Ligand Ephrin-B2
Yong Yue, David A. J. Widmer, Alycia K. Halladay, Douglas Pat Cerretti, George C. Wagner, Jean-Luc Dreyer, Renping Zhou
J Neurosci. 1999 Mar 15; 19(6): 2090–2101. doi: 10.1523/JNEUROSCI.19-06-02090.1999
PMCID:
PMC6782574
AbstractArticlePDF–1.3M
7.
EphB Receptors Regulate Stem/Progenitor Cell Proliferation, Migration, and Polarity during Hippocampal Neurogenesis
Michael J. Chumley, Timothy Catchpole, Robert E. Silvany, Steven G. Kernie, Mark Henkemeyer
J Neurosci. 2007 Dec 5; 27(49): 13481–13490. doi: 10.1523/JNEUROSCI.4158-07.2007
PMCID:
PMC6673089
AbstractArticlePDF–598K
8.
Targeting promiscuous heterodimerization overcomes innate resistance to ERBB2 dimerization inhibitors in breast cancer
Sean P. Kennedy, Jeremy Z. R. Han, Neil Portman, Max Nobis, Jordan F. Hastings, Kendelle J. Murphy, Sharissa L. Latham, Antonia L. Cadell, Dushan Miladinovic, Gabriella R. Marriott, Yolande E. I. O’Donnell, Robert F. Shearer, James T. Williams, Amaya Garcia Munoz, Thomas R. Cox, D. Neil Watkins, Darren N. Saunders, Paul Timpson, Elgene Lim, Walter Kolch, David R. Croucher
Breast Cancer Res. 2019; 21: 43. Published online 2019 Mar 21. doi: 10.1186/s13058-019-1127-y
PMCID:
PMC6429830
AbstractArticlePDF–3.1M
9.
Regulation of Connexin32 by ephrin receptors and T-cell protein-tyrosine phosphatase
Andrew J. Trease, Hanjun Li, Gaelle Spagnol, Li Zheng, Kelly L. Stauch, Paul L. Sorgen
J Biol Chem. 2019 Jan 4; 294(1): 341–350. Published online 2018 Nov 6. doi: 10.1074/jbc.RA118.003883
PMCID:
PMC6322898
AbstractArticlePDF–1.6M
10.
Architecture of the human interactome defines protein communities and disease networks
Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper
Nature. Author manuscript; available in PMC 2017 Nov 17.
Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366
PMCID:
PMC5531611
AbstractArticlePDF–2.7M
11.
EphB1 Suppression in Acute Myelogenous Leukemia: Regulating the DNA Damage Control System
K.R. Kampen, F.J.G. Scherpen, G. Garcia-Manero, H. Yang, G.J.L. Kaspers, J. Cloos, C.M. Zwaan, M.M. van den Heuvel-Eibrink, S.M. Kornblau, E.S.J.M. De Bont
Mol Cancer Res. Author manuscript; available in PMC 2016 Aug 15.
Published in final edited form as: Mol Cancer Res. 2015 Jun; 13(6): 982–992. Published online 2015 May 5. doi: 10.1158/1541-7786.MCR-14-0660-T
PMCID:
PMC4983719
AbstractArticlePDF–1.3M
12.
Knockdown of EphB1 receptor decreases medulloblastoma cell growth and migration and increases cellular radiosensitization
Shilpa Bhatia, Nimrah A. Baig, Olga Timofeeva, Elena B. Pasquale, Kellen Hirsch, Tobey J. MacDonald, Anatoly Dritschilo, Yi Chien Lee, Mark Henkemeyer, Brian Rood, Mira Jung, Xiao-Jing Wang, Marcel Kool, Olga Rodriguez, Chris Albanese, Sana D. Karam
Oncotarget. 2015 Apr 20; 6(11): 8929–8946. Published online 2015 Mar 30. doi: 10.18632/oncotarget.3369
PMCID:
PMC4496193
AbstractArticlePDF–4.7M
13.
A genome-wide association study points to multiple loci predicting antidepressant treatment outcome in depression
Marcus Ising, Susanne Lucae, Elisabeth B. Binder, Thomas Bettecken, Manfred Uhr, Stephan Ripke, Martin A. Kohli, Johannes M. Hennings, Sonja Horstmann, Stefan Kloiber, Andreas Menke, Brigitta Bondy, Rainer Rupprecht, Katharina Domschke, Bernhard T. Baune, Volker Arolt, A. John Rush, Florian Holsboer, Bertram Müller-Myhsok
Arch Gen Psychiatry. Author manuscript; available in PMC 2015 Jun 14.
Published in final edited form as: Arch Gen Psychiatry. 2009 Sep; 66(9): 966–975. doi: 10.1001/archgenpsychiatry.2009.95
PMCID:
PMC4465570
AbstractArticlePDF–2.3M
14.
Decreased expression of receptor tyrosine kinase of EphB1 protein in renal cell carcinomas
Shuigen Zhou, Longxin Wang, Guimei Li, Zhengyu Zhang, Jiandong Wang
Int J Clin Exp Pathol. 2014; 7(7): 4254–4260. Published online 2014 Jun 15.
PMCID:
PMC4129041
AbstractArticlePDF–1.0M
15.
Completing the structural family portrait of the human EphB tyrosine kinase domains
Ross C Overman, Judit E Debreczeni, Caroline M Truman, Mark S McAlister, Teresa K Attwood
Protein Sci. 2014 May; 23(5): 627–638. Published online 2014 Mar 11. doi: 10.1002/pro.2445
PMCID:
PMC4005714
AbstractArticlePDF–405K
16.
Quantitative Analysis of Hsp90-Client Interactions Reveals Principles of Substrate Recognition
Mikko Taipale, Irina Krykbaeva, Martina Koeva, Can Kayatekin, Kenneth D. Westover, Georgios I. Karras, Susan Lindquist
Cell. Author manuscript; available in PMC 2014 Jan 17.
Published in final edited form as: Cell. 2012 Aug 31; 150(5): 987–1001. doi: 10.1016/j.cell.2012.06.047
PMCID:
PMC3894786
AbstractArticlePDF–5.0M
17.
Loss of expression of EphB1 protein in serous carcinoma of ovary associated with metastasis and poor survival
Haiyan Wang, Juanjuan Wen, Hai Wang, Qinq Guo, Shanshan Shi, Qunli Shi, Xiaojun Zhou, Qi Liu, Guangming Lu, Jiandong Wang
Int J Clin Exp Pathol. 2014; 7(1): 313–321. Published online 2013 Dec 15.
PMCID:
PMC3885486
AbstractArticlePDF–699K
18.
Ligand-dependent EphB1 signaling suppresses glioma invasion and correlates with patient survival
Lei Teng, Mitsutoshi Nakada, Natsuki Furuyama, Hemragul Sabit, Takuya Furuta, Yutaka Hayashi, Takahisa Takino, Yu Dong, Hiroshi Sato, Yoshimichi Sai, Ken-ichi Miyamoto, Michael E. Berens, Shi-Guang Zhao, Jun-Ichiro Hamada
Neuro Oncol. 2013 Dec; 15(12): 1710–1720. Published online 2013 Oct 11. doi: 10.1093/neuonc/not128
PMCID:
PMC3829595
AbstractArticlePDF–866K
19.
Genome-Wide Association for Abdominal Subcutaneous and Visceral Adipose Reveals a Novel Locus for Visceral Fat in Women
Caroline S. Fox, Yongmei Liu, Charles C. White, Mary Feitosa, Albert V. Smith, Nancy Heard-Costa, Kurt Lohman, GIANT Consortium, MAGIC Consortium, GLGC Consortium, Andrew D. Johnson, Meredith C. Foster, Danielle M. Greenawalt, Paula Griffin, Jinghong Ding, Anne B. Newman, Fran Tylavsky, Iva Miljkovic, Stephen B. Kritchevsky, Lenore Launer, Melissa Garcia, Gudny Eiriksdottir, J. Jeffrey Carr, Vilmunder Gudnason, Tamara B. Harris, L. Adrienne Cupples, Ingrid B. Borecki
PLoS Genet. 2012 May; 8(5): e1002695. Published online 2012 May 10. doi: 10.1371/journal.pgen.1002695
PMCID:
PMC3349734
AbstractArticlePDF–377K
20.
Resequencing and Association Analysis of the KALRN and EPHB1 Genes And Their Contribution to Schizophrenia Susceptibility
Itaru Kushima, Yukako Nakamura, Branko Aleksic, Masashi Ikeda, Yoshihito Ito, Tomoko Shiino, Tomo Okochi, Yasuhisa Fukuo, Hiroshi Ujike, Michio Suzuki, Toshiya Inada, Ryota Hashimoto, Masatoshi Takeda, Kozo Kaibuchi, Nakao Iwata, Norio Ozaki
Schizophr Bull. 2012 May; 38(3): 552–560. Published online 2010 Nov 1. doi: 10.1093/schbul/sbq118
PMCID:
PMC3329972
AbstractArticlePDF–212K

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