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Select item 109168661.

Cooperative polarization of MCAM/CD146 and ERM family proteins in melanoma

Suzannah G. Miller, Maria Hoh, Christopher C. Ebmeier, Jian Wei Tay, Natalie G. Ahn

Mol Biol Cell. 2024 Mar 1; 35(3): ar31. Published online 2024 Jan 29. doi: 10.1091/mbc.E23-06-0255

PMCID:: PMC10916866

Abstract Article PDF–4.7M

Select item 108559832.

Chondroitin Sulfate Proteoglycan 4 Provides New Treatment Approach to Preventing Peritoneal Dissemination in Ovarian Cancer

Kaname Uno, Yoshihiro Koya, Masato Yoshihara, Shohei Iyoshi, Kazuhisa Kitami, Mai Sugiyama, Emiri Miyamoto, Kazumasa Mogi, Hiroki Fujimoto, Yoshihiko Yamakita, Xinhui Wang, Akihiro Nawa, Hiroaki Kajiyama

Int J Mol Sci. 2024 Feb; 25(3): 1626. Published online 2024 Jan 28. doi: 10.3390/ijms25031626

PMCID:: PMC10855983

Abstract Article PDF–16M

Select item 104052773.

DISRUPTING MECHANICAL HOMEOSTASIS PROMOTES MATRIX METALLOPROTEINASE-13 MEDIATED PROCESSING OF NEURON GLIAL ANTIGEN 2 IN MANDIBULAR CONDYLAR CARTILAGE

M. Bagheri Varzaneh, Y. Zhao, J. Rozynek, M. Han, D.A. Reed

Eur Cell Mater. Author manuscript; available in PMC 2023 Aug 7.

Published in final edited form as: Eur Cell Mater. 2023 May 8; 45: 113–130. Published online 2023 May 8. doi: 10.22203/eCM.v045a08

PMCID:: PMC10405277

Abstract Article PDF–2.5M

Select item 102374224.

TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing

Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan

Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233

PMCID:: PMC10237422

Abstract Article PDF–23M

Select item 100792255.

Discovery of Hippo signaling as a regulator of CSPG4 expression and as a therapeutic target for Clostridioides difficile disease

Jason L. Larabee, D. Annie Doyle, Ummey Khalecha Bintha Ahmed, Tyler M. Shadid, Rachel R. Sharp, Kenneth L. Jones, Young Mi Kim, Shibo Li, Jimmy D. Ballard

PLoS Pathog. 2023 Mar; 19(3): e1011272. Published online 2023 Mar 27. doi: 10.1371/journal.ppat.1011272

PMCID:: PMC10079225

Abstract Article PDF–2.1M

Select item 98646656.

Neuron-Glial Antigen 2 Participates in Liver Fibrosis via Regulating the Differentiation of Bone Marrow Mesenchymal Stem Cell to Myofibroblast

Le Yang, Hang Zhang, Chengbin Dong, Wenhui Yue, Renmin Xue, Fuquan Liu, Lin Yang, Liying Li

Int J Mol Sci. 2023 Jan; 24(2): 1177. Published online 2023 Jan 7. doi: 10.3390/ijms24021177

PMCID:: PMC9864665

Abstract Article PDF–3.1M

Select item 95973847.

Evolutionary trajectory of receptor binding specificity and promiscuity of the spike protein of SARS‐CoV‐2

Cyril Planchais, Alejandra Reyes‐Ruiz, Robin Lacombe, Alessandra Zarantonello, Maxime Lecerf, Margot Revel, Lubka T. Roumenina, Boris P. Atanasov, Hugo Mouquet, Jordan D. Dimitrov

Protein Sci. 2022 Nov; 31(11): e4447. Published online 2022 Oct 26. doi: 10.1002/pro.4447

PMCID:: PMC9597384

Abstract Article PDF–5.4M

Select item 95524058.

CSPG4 expression in soft tissue sarcomas is associated with poor prognosis and low cytotoxic immune response

Laurys Boudin, A de Nonneville, Pascal Finetti, Léna Mescam, A Le Cesne, Antoine Italiano, Jean-Yves Blay, Daniel Birnbaum, Emilie Mamessier, François Bertucci

J Transl Med. 2022; 20: 464. Published online 2022 Oct 11. doi: 10.1186/s12967-022-03679-y

PMCID:: PMC9552405

Abstract Article PDF–1.0M

Select item 94754539.

The N⁶-methyladenosine-mediated lncRNA WEE2-AS1 promotes glioblastoma progression by stabilizing RPN2

Boyan Li, Rongrong Zhao, Wei Qiu, Ziwen Pan, Shulin Zhao, Yanhua Qi, Jiawei Qiu, Shouji Zhang, Qindong Guo, Yang Fan, Hao Xu, Ming Li, Gang Li, Hao Xue

Theranostics. 2022; 12(14): 6363–6379. Published online 2022 Aug 29. doi: 10.7150/thno.74600

PMCID:: PMC9475453

Abstract Article PDF–4.4M

Select item 926261410.

A dual-activity topoisomerase complex regulates mRNA translation and turnover

Shuaikun Su, Yutong Xue, Alexei Sharov, Yongqing Zhang, Seung Kyu Lee, Jennifer L Martindale, Wen Li, Wai Lim Ku, Keji Zhao, Supriyo De, Weiping Shen, Payel Sen, Myriam Gorospe, Dongyi Xu, Weidong Wang

Nucleic Acids Res. 2022 Jul 8; 50(12): 7013–7033. Published online 2022 Jun 24. doi: 10.1093/nar/gkac538

PMCID:: PMC9262614

Abstract Article PDF–3.6M

Select item 923162311.

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1

Boris Simonetti, James L. Daly, Lorena Simón-Gracia, Katja Klein, Saroja Weeratunga, Carlos Antón-Plágaro, Allan Tobi, Lorna Hodgson, Philip A. Lewis, Kate J. Heesom, Deborah K. Shoemark, Andrew D. Davidson, Brett M. Collins, Tambet Teesalu, Yohei Yamauchi, Peter J. Cullen

Proc Natl Acad Sci U S A. 2022 Jun 21; 119(25): e2201980119. Published online 2022 Jun 13. doi: 10.1073/pnas.2201980119

PMCID:: PMC9231623

Abstract Article PDF–6.0M

Select item 895660412.

CRISPR activation screen identifies BCL-2 proteins and B3GNT2 as drivers of cancer resistance to T cell-mediated cytotoxicity

Julia Joung, Paul C. Kirchgatterer, Ankita Singh, Jang H. Cho, Suchita P. Nety, Rebecca C. Larson, Rhiannon K. Macrae, Rebecca Deasy, Yuen-Yi Tseng, Marcela V. Maus, Feng Zhang

Nat Commun. 2022; 13: 1606. Published online 2022 Mar 25. doi: 10.1038/s41467-022-29205-8

PMCID:: PMC8956604

Abstract Article PDF–3.9M

Select item 891788413.

CSPG4 Is a Potential Therapeutic Target in Anaplastic Thyroid Cancer

Caitlin E. Egan, Dessislava Stefanova, Adnan Ahmed, Vijay J. Raja, Jessica W. Thiesmeyer, Kevin J. Chen, Jacques A. Greenberg, Taotao Zhang, Bing He, Brendan M. Finnerty, Rasa Zarnegar, Moonsoo M. Jin, Theresa Scognamiglio, Noah Dephoure, Thomas Fahey, III, Irene M. Min

Thyroid. October 2021; 31(10): 1481–1493. Published online 2021 Oct 18. doi: 10.1089/thy.2021.0067

PMCID:: PMC8917884

Abstract Article PDF–837K

Select item 870803314.

CSPG4 as a prognostic biomarker in chordoma

Andrew J. Schoenfeld, Xinhui Wang, Yangyang Wang, Francis J. Hornicek, G. Petur Nielsen, Zhenfeng Duan, Soldano Ferrone, Joseph H. Schwab

Spine J. Author manuscript; available in PMC 2021 Dec 24.

Published in final edited form as: Spine J. 2016 Jun; 16(6): 722–727. Published online 2015 Dec 9. doi: 10.1016/j.spinee.2015.11.059

PMCID:: PMC8708033

Abstract Article PDF–238K

Select item 833303815.

Identification of a germline CSPG4 variation in a family with neurofibromatosis type 1-like phenotype

Zhuanli Bai, Yiping Qu, Lin Shi, Xinju Li, Zhen Yang, Meiju Ji, Peng Hou

Cell Death Dis. 2021 Aug; 12(8): 765. Published online 2021 Aug 3. doi: 10.1038/s41419-021-04056-1

PMCID:: PMC8333038

Abstract Article PDF–2.8M

Select item 828276416.

N6-methyladenosine on mRNA facilitates a phase-separated nuclear body that suppresses myeloid leukemic differentiation

Yuanming Cheng, Wei Xie, Brian F Pickering, Karen L Chu, Angela M Savino, Xuejing Yang, Hanzhi Luo, Diu TT Nguyen, Shanlan Mo, Ersilia Barin, Anthony Velleca, Thomas Rohwetter, Dinshaw J Patel, Samie R Jaffrey, Michael G Kharas

Cancer Cell. Author manuscript; available in PMC 2022 Jul 12.

Published in final edited form as: Cancer Cell. 2021 Jul 12; 39(7): 958–972.e8. Published online 2021 May 27. doi: 10.1016/j.ccell.2021.04.017

PMCID:: PMC8282764

Abstract Article PDF–3.4M

Select item 816503017.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 807872818.

Characterization of the Extracellular Matrix of Normal and Diseased Tissues Using Proteomics

Alexandra Naba, Oliver M. T. Pearce, Amanda Del Rosario, Duanduan Ma, Huiming Ding, Vinothini Rajeeve, Pedro R. Cutillas, Frances R. Balkwill, Richard O. Hynes

J Proteome Res. Author manuscript; available in PMC 2021 Apr 27.

Published in final edited form as: J Proteome Res. 2017 Aug 4; 16(8): 3083–3091. Published online 2017 Jul 19. doi: 10.1021/acs.jproteome.7b00191

PMCID:: PMC8078728

Abstract Article PDF–2.1M

Select item 796639819.

NG2/CSPG4, CD146/MCAM and VAP1/AOC3 are regulated by myocardin-related transcription factors in smooth muscle cells

Catarina Rippe, Björn Morén, Li Liu, Karin G. Stenkula, Johan Mustaniemi, Malin Wennström, Karl Swärd

Sci Rep. 2021; 11: 5955. Published online 2021 Mar 16. doi: 10.1038/s41598-021-85335-x

PMCID:: PMC7966398

Abstract Article PDF–13M

Select item 787698720.

Expression of chondroitin sulfate proteoglycan 4 (CSPG4) in melanoma cells is downregulated upon inhibition of BRAF

Karolina Uranowska, Tanja Kalic, Veronika Valtsanidis, Melitta Kitzwögerer, Heimo Breiteneder, Christine Hafner

Oncol Rep. 2021 Apr; 45(4): 14. Published online 2021 Feb 2. doi: 10.3892/or.2021.7965

PMCID:: PMC7876987

Abstract Article PDF–2.0M

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