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Select item 109533361.

hSSB1 (NABP2/OBFC2B) modulates the DNA damage and androgen‐induced transcriptional response in prostate cancer

Mark N. Adams, Phd, Laura V. Croft, PhD, Aaron Urquhart, PhD, Mohamed Ashick Mohamed Saleem, PhD, Anja Rockstroh, PhD, Pascal H. G. Duijf, Phd, Patrick B. Thomas, PhD, Genevieve P. Ferguson, BSc, Idris Mohd Najib, MPhil, Esha T. Shah, PhD, Emma Bolderson, PhD, Shivashankar Nagaraj, PhD, Elizabeth D. Williams, PhD, Colleen C. Nelson, PhD, Kenneth J. O'Byrne, MD, Derek J. Richard, PhD

Prostate. 2023 May 15; 83(7): 628–640. Published online 2023 Feb 22. doi: 10.1002/pros.24496

PMCID:: PMC10953336

Abstract Article PDF–2.3M

Select item 93485762.

Chr21 protein–protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer’s disease

Julia Viard, Yann Loe-Mie, Rachel Daudin, Malik Khelfaoui, Christine Plancon, Anne Boland, Francisco Tejedor, Richard L Huganir, Eunjoon Kim, Makoto Kinoshita, Guofa Liu, Volker Haucke, Thomas Moncion, Eugene Yu, Valérie Hindie, Henri Bléhaut, Clotilde Mircher, Yann Herault, Jean-François Deleuze, Jean-Christophe Rain, Michel Simonneau, Aude-Marie Lepagnol-Bestel

Life Sci Alliance. 2022 Dec; 5(12): e202101205. Published online 2022 Aug 1. doi: 10.26508/lsa.202101205

PMCID:: PMC9348576

Abstract Article PDF–3.0M

Select item 92792853.

Scalable multiplex co-fractionation/mass spectrometry platform for accelerated protein interactome discovery

Pierre C. Havugimana, Raghuveera Kumar Goel, Sadhna Phanse, Ahmed Youssef, Dzmitry Padhorny, Sergei Kotelnikov, Dima Kozakov, Andrew Emili

Nat Commun. 2022; 13: 4043. Published online 2022 Jul 13. doi: 10.1038/s41467-022-31809-z

PMCID:: PMC9279285

Abstract Article PDF–2.5M

Select item 91197364.

OpenCell: proteome-scale endogenous tagging enables the cartography of human cellular organization

Nathan H. Cho, Keith C. Cheveralls, Andreas-David Brunner, Kibeom Kim, André C. Michaelis, Preethi Raghavan, Hirofumi Kobayashi, Laura Savy, Jason Y. Li, Hera Canaj, James Y.S. Kim, Edna M. Stewart, Christian Gnann, Frank McCarthy, Joana P. Cabrera, Rachel M. Brunetti, Bryant B. Chhun, Greg Dingle, Marco Y. Hein, Bo Huang, Shalin B. Mehta, Jonathan S. Weissman, Rafael Gómez-Sjöberg, Daniel N. Itzhak, Loic A. Royer, Matthias Mann, Manuel D. Leonetti

Science. Author manuscript; available in PMC 2022 Sep 11.

Published in final edited form as: Science. 2022 Mar 11; 375(6585): eabi6983. Published online 2022 Mar 11. doi: 10.1126/science.abi6983

PMCID:: PMC9119736

Abstract Article PDF–3.3M

Select item 91052355.

Cullin 3 Exon 9 Deletion in Familial Hyperkalemic Hypertension Impairs Cullin3-Ring-E3 Ligase (CRL3) Dynamic Regulation and Cycling

Ilektra Kouranti, Waed Abdel Khalek, Stephani Mazurkiewicz, Irmine Loisel-Ferreira, Alexis M. Gautreau, Lionel Pintard, Xavier Jeunemaitre, Eric Clauser

Int J Mol Sci. 2022 May; 23(9): 5151. Published online 2022 May 5. doi: 10.3390/ijms23095151

PMCID:: PMC9105235

Abstract Article PDF–5.8M

Select item 85264126.

Mechanisms of SSBP1 variants in mitochondrial disease: Molecular dynamics simulations reveal stable tetramers with altered DNA binding surfaces

Margaret A. Gustafson, Lalith Perera, Min Shi, William C. Copeland

DNA Repair (Amst) Author manuscript; available in PMC 2022 Nov 1.

Published in final edited form as: DNA Repair (Amst). 2021 Nov; 107: 103212. Published online 2021 Aug 17. doi: 10.1016/j.dnarep.2021.103212

PMCID:: PMC8526412

Abstract Article PDF–3.1M

Select item 83641817.

Protein interaction landscapes revealed by advanced in vivo cross-linking–mass spectrometry

Andrew Wheat, Clinton Yu, Xiaorong Wang, Anthony M. Burke, Ilan E. Chemmama, Robyn M. Kaake, Peter Baker, Scott D. Rychnovsky, Jing Yang, Lan Huang

Proc Natl Acad Sci U S A. 2021 Aug 10; 118(32): e2023360118. Published online 2021 Aug 4. doi: 10.1073/pnas.2023360118

PMCID:: PMC8364181

Abstract Article PDF–3.0M

Select item 83529648.

Integrative oncogene-dependency mapping identifies RIT1 vulnerabilities and synergies in lung cancer

Athea Vichas, Amanda K. Riley, Naomi T. Nkinsi, Shriya Kamlapurkar, Phoebe C. R. Parrish, April Lo, Fujiko Duke, Jennifer Chen, Iris Fung, Jacqueline Watson, Matthew Rees, Austin M. Gabel, James D. Thomas, Robert K. Bradley, John K. Lee, Emily M. Hatch, Marina K. Baine, Natasha Rekhtman, Marc Ladanyi, Federica Piccioni, Alice H. Berger

Nat Commun. 2021; 12: 4789. Published online 2021 Aug 9. doi: 10.1038/s41467-021-24841-y

PMCID:: PMC8352964

Abstract Article PDF–4.5M

Select item 81650309.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 731146710.

SUMOylation stabilizes hSSB1 and enhances the recruitment of NBS1 to DNA damage sites

Liwen Zhou, Lisi Zheng, Kaishun Hu, Xin Wang, Ruhua Zhang, Yezi Zou, Li Zhong, Shang Wang, Yuanzhong Wu, Tiebang Kang

Signal Transduct Target Ther. 2020; 5: 80. Published online 2020 Jun 24. doi: 10.1038/s41392-020-0172-4

PMCID:: PMC7311467

Abstract Article PDF–3.9M

Select item 583915811.

Quantitative mapping of RNA-mediated nuclear estrogen receptor β interactome in human breast cancer cells

Giorgio Giurato, Giovanni Nassa, Annamaria Salvati, Elena Alexandrova, Francesca Rizzo, Tuula A. Nyman, Alessandro Weisz, Roberta Tarallo

Sci Data. 2018; 5: 180031. Published online 2018 Mar 6. doi: 10.1038/sdata.2018.31

PMCID:: PMC5839158

Abstract Article PDF–1.9M

Select item 566346512.

A Global Analysis of The Receptor Tyrosine Kinase – Protein Phosphatase Interactome

Zhong Yao, Katelyn Darowski, Nicole St-Denis, Victoria Wong, Fabian Offensperger, Annabel Villedieu, Shahreen Amin, Ramy Malty, Hiroyuki Aoki, Hongbo Guo, Yang Xu, Caterina Iorio, Max Kotlyar, Andrew Emili, Igor Jurisica, Benjamin G Neel, Mohan Babu, Anne-Claude Gingras, Igor Stagljar

Mol Cell. Author manuscript; available in PMC 2017 Oct 31.

Published in final edited form as: Mol Cell. 2017 Jan 19; 65(2): 347–360. Published online 2017 Jan 5. doi: 10.1016/j.molcel.2016.12.004

PMCID:: PMC5663465

Abstract Article PDF–2.1M

Select item 543302813.

hSSB1 associates with and promotes stability of the BLM helicase

Laura V. Croft, Nicholas W. Ashton, Nicolas Paquet, Emma Bolderson, Kenneth J. O’Byrne, Derek J. Richard

BMC Mol Biol. 2017; 18: 13. Published online 2017 May 15. doi: 10.1186/s12867-017-0090-3

PMCID:: PMC5433028

Abstract Article PDF–2.2M

Select item 503652714.

Panorama of ancient metazoan macromolecular complexes

Cuihong Wan, Blake Borgeson, Sadhna Phanse, Fan Tu, Kevin Drew, Greg Clark, Xuejian Xiong, Olga Kagan, Julian Kwan, Alexandr Berzginov, Kyle Chessman, Swati Pal, Graham Cromar, Ophelia Papoulas, Zuyao Ni, Daniel R. Boutz, Snejana Stoilova, Pierre C. Havugimana, Xinghua Guo, Ramy H. Malty, Mihail Sarov, Jack Greenblatt, Mohan Babu, Brent Derry, Elisabeth Tillier, John B. Wallingford, John Parkinson, Edward M. Marcotte, Andrew Emili

Nature. Author manuscript; available in PMC 2016 Sep 26.

Published in final edited form as: Nature. 2015 Sep 17; 525(7569): 339–344. Published online 2015 Sep 7. doi: 10.1038/nature14877

PMCID:: PMC5036527

Abstract Article PDF–4.7M

Select item 502750315.

A structural analysis of DNA binding by hSSB1 (NABP2/OBFC2B) in solution

Christine Touma, Ruvini Kariawasam, Adrian X. Gimenez, Ray E. Bernardo, Nicholas W. Ashton, Mark N. Adams, Nicolas Paquet, Tristan I. Croll, Kenneth J. O'Byrne, Derek J. Richard, Liza Cubeddu, Roland Gamsjaeger

Nucleic Acids Res. 2016 Sep 19; 44(16): 7963–7973. Published online 2016 Jul 7. doi: 10.1093/nar/gkw617

PMCID:: PMC5027503

Abstract Article PDF–3.5M

Select item 489765416.

hSSB1 (NABP2/OBFC2B) is regulated by oxidative stress

Nicolas Paquet, Mark N. Adams, Nicholas W. Ashton, Christine Touma, Roland Gamsjaeger, Liza Cubeddu, Vincent Leong, Sam Beard, Emma Bolderson, Catherine H. Botting, Kenneth J. O’Byrne, Derek J. Richard

Sci Rep. 2016; 6: 27446. Published online 2016 Jun 8. doi: 10.1038/srep27446

PMCID:: PMC4897654

Abstract Article PDF–1.7M

Select item 465275317.

Acetylation-dependent function of human single-stranded DNA binding protein 1

Yuanzhong Wu, Hongxia Chen, Jinping Lu, Meifang Zhang, Ruhua Zhang, Tingmei Duan, Xin Wang, Jun Huang, Tiebang Kang

Nucleic Acids Res. 2015 Sep 18; 43(16): 7878–7887. Published online 2015 Jul 13. doi: 10.1093/nar/gkv707

PMCID:: PMC4652753

Abstract Article PDF–7.2M

Select item 464794118.

hORFeome v3.1: A resource of human open reading frames representing over 10,000 human genes

Philippe Lamesch, Ning Li, Stuart Milstein, Changyu Fan, Tong Hao, Gabor Szabo, Zhenjun Hu, Kavitha Venkatesan, Graeme Bethel, Paul Martin, Jane Rogers, Stephanie Lawlor, Stuart McLaren, Amélie Dricot, Heather Borick, Michael E. Cusick, Jean Vandenhaute, Ian Dunham, David E. Hill, Marc Vidal

Genomics. 2007 Mar; 89(3): 307–315. doi: 10.1016/j.ygeno.2006.11.012

PMCID:: PMC4647941

Abstract Article

Select item 460530119.

hSSB1 (NABP2/ OBFC2B) is required for the repair of 8-oxo-guanine by the hOGG1-mediated base excision repair pathway

Nicolas Paquet, Mark N. Adams, Vincent Leong, Nicholas W. Ashton, Christine Touma, Roland Gamsjaeger, Liza Cubeddu, Sam Beard, Joshua T. Burgess, Emma Bolderson, Ken J. O'Byrne, Derek J. Richard

Nucleic Acids Res. 2015 Oct 15; 43(18): 8817–8829. Published online 2015 Oct 10. doi: 10.1093/nar/gkv790

PMCID:: PMC4605301

Abstract Article PDF–3.9M

Select item 435749620.

A DNA Damage Response Screen Identifies RHINO: a 9-1-1 and TopBP1 interacting protein required for ATR signaling

Cecilia Cotta-Ramusino, E. Robert McDonald 3, 3rd, Kristen Hurov, Mathew E. Sowa, J. Wade Harper, Stephen J. Elledge

Science. Author manuscript; available in PMC 2015 Mar 12.

Published in final edited form as: Science. 2011 Jun 10; 332(6035): 1313–1317. doi: 10.1126/science.1203430

PMCID:: PMC4357496

Abstract Article PDF–816K

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