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Select item 112696361.

Genetic variation in NOTCH1 is associated with overweight and obesity in Brazilian elderly

Estevão Carlos Silva Barcelos, Michel Satya Naslavsky, Izadora Silveira Fernandes, Marilia Oliveira Scliar, Guilherme Lopes Yamamoto, Jaqueline Yu Ting Wang, Laís Bride, Valdemir Pereira de Sousa, Lucia Helena Sagrillo Pimassoni, Paolo Sportoletti, Flavia de Paula, Sandra Ventorin von Zeidler, Yeda Aparecida Oliveira Duarte, Maria Rita Passos-Bueno, Mayana Zatz, Flávia Imbroisi Valle Errera

Sci Rep. 2024; 14: 17096. Published online 2024 Jul 24. doi: 10.1038/s41598-024-65771-1

PMCID:: PMC11269636

Abstract Article PDF–1.4M

Select item 112199832.

Expanding the phenotypic spectrum of NOTCH1 variants: clinical manifestations in families with congenital heart disease

Kaitlin J. Stanley, Kelsey J. Kalbfleisch, Olivia M. Moran, Rajiv R. Chaturvedi, Maian Roifman, Xin Chen, Roozbeh Manshaei, Nicole Martin, Simina McDermott, Vanda McNiven, Diane Myles-Reid, Lynne E. Nield, Miriam S. Reuter, Marci L. B. Schwartz, Patrick Shannon, Rachel Silver, Cherith Somerville, Ronni Teitelbaum, Laura Zahavich, Anne S. Bassett, Raymond H. Kim, Seema Mital, David Chitayat, Rebekah K. Jobling

Eur J Hum Genet. 2024 Jul; 32(7): 795–803. Published online 2024 May 22. doi: 10.1038/s41431-024-01629-4

PMCID:: PMC11219983

Abstract Article PDF–3.5M

Select item 111598823.

Overexpression of ΔNp63α induces a stem cell phenotype in MCF7 breast carcinoma cell line through the Notch pathway

Zhijian Du, Jing Li, Liang Wang, Chunjing Bian, Qingliang Wang, Lianming Liao, Xiaowei Dou, Xiuwu Bian, Robert Chunhua Zhao

Cancer Sci. 2010 Nov; 101(11): 2417–2424. Published online 2010 Aug 2. doi: 10.1111/j.1349-7006.2010.01700.x

PMCID:: PMC11159882

Abstract Article PDF–1.0M

Select item 111592664.

Notch1 oncoprotein antagonizes TGF‐β/Smad‐mediated cell growth suppression via sequestration of coactivator p300

Shigeo Masuda, Keiki Kumano, Kiyoshi Shimizu, Yoichi Imai, Mineo Kurokawa, Seishi Ogawa, Makoto Miyagishi, Kazunari Taira, Hisamaru Hirai, Shigeru Chiba

Cancer Sci. 2005 May; 96(5): 274–282. Published online 2005 May 19. doi: 10.1111/j.1349-7006.2005.00048.x

PMCID:: PMC11159266

Abstract Article PDF–314K

Select item 110799915.

Analysis of Notch1 protein expression in methotrexate-associated lymphoproliferative disorders

Takeshi Okatani, Midori Filiz Nishimura, Yuria Egusa, Sayako Yoshida, Yoshito Nishimura, Asami Nishikori, Tadashi Yoshino, Hidetaka Yamamoto, Yasuharu Sato

J Clin Exp Hematop. 2024 Mar; 64(1): 1–9. Published online 2024 Jan 28. doi: 10.3960/jslrt.23038

PMCID:: PMC11079991

Abstract Article PDF–800K

Select item 110722866.

Kindlin-2 controls angiogenesis through modulating Notch1 signaling

Yuechao Dong, Guixing Ma, Xiaoting Hou, Yingying Han, Zhen Ding, Wanze Tang, Litong Chen, Yangshan Chen, Bo Zhou, Feng Rao, Kaosheng Lv, Changzheng Du, Huiling Cao

Cell Mol Life Sci. 2023 Aug; 80(8): 223. Published online 2023 Jul 22. doi: 10.1007/s00018-023-04866-w

PMCID:: PMC11072286

Abstract Article PDF–5.5M

Select item 110344937.

Inhibition of SUV39H1 reduces tumor angiogenesis via Notch1 in oral squamous cell carcinoma

Yan Chen, Xiuhong Weng, Chuanjie Zhang, Simin Wang, Xuechen Wu, Bo Cheng

PeerJ. 2024; 12: e17222. Published online 2024 Apr 19. doi: 10.7717/peerj.17222

PMCID:: PMC11034493

Abstract Article PDF–12M

Select item 109323108.

Stefania Della Vecchia, Alessandra Tessa, Rosa Pasquariello, Luis Seabra, Yanick J. Crow, Roberta Battini

Int J Mol Sci. 2024 Mar; 25(5): 2864. Published online 2024 Mar 1. doi: 10.3390/ijms25052864

PMCID:: PMC10932310

Abstract Article PDF–5.0M

Select item 109200869.

ASPM stabilizes the NOTCH intracellular domain 1 and promotes oncogenesis by blocking FBXW7 binding in hepatocellular carcinoma cells

Tze‐Sian Chan, Li‐Hsin Cheng, Chung‐Chi Hsu, Pei‐Ming Yang, Tai‐Yan Liao, Hsiao‐Yen Hsieh, Pei‐Chun Lin, Wei‐Chun HuangFu, Chih‐Pin Chuu, Kelvin K. Tsai

Mol Oncol. 2024 Mar; 18(3): 562–579. Published online 2024 Jan 26. doi: 10.1002/1878-0261.13589

PMCID:: PMC10920086

Abstract Article PDF–6.1M

Select item 1086442510.

FBP1 inhibits NSCLC stemness by promoting ubiquitination of Notch1 intracellular domain and accelerating degradation

Tianyu He, Yanye Wang, Wang Lv, Yiqing Wang, Xinye Li, Qingyi Zhang, Han-Ming Shen, Jian Hu

Cell Mol Life Sci. 2024 Dec; 81(1): 87. Published online 2024 Feb 13. doi: 10.1007/s00018-024-05138-x

PMCID:: PMC10864425

Abstract Article PDF–6.4M

Select item 1085079911.

NOTCH1 and CREBBP co‐mutations negatively affect the benefit of adjuvant therapy in completely resected EGFR‐mutated NSCLC: translational research of phase III IMPACT study

Satoshi Ikeda, Masahiro Tsuboi, Kazuko Sakai, Toshihiro Misumi, Hiroaki Akamatsu, Hiroyasu Shoda, Noriaki Sakakura, Atsushi Nakamura, Yasuhisa Ohde, Hidetoshi Hayashi, Kyoichi Okishio, Morihito Okada, Ichiro Yoshino, Jiro Okami, Kazuhisa Takahashi, Norihiko Ikeda, Masayuki Tanahashi, Yuichi Tambo, Haruhiro Saito, Shinichi Toyooka, Hidetoshi Inokawa, Toyofumi Chen‐Yoshikawa, Toshihide Yokoyama, Tatsuro Okamoto, Noriko Yanagitani, Masahide Oki, Makoto Takahama, Kenji Sawa, Hirohito Tada, Kazuhiko Nakagawa, Tetsuya Mitsudomi, Kazuto Nishio

Mol Oncol. 2024 Feb; 18(2): 305–316. Published online 2023 Oct 28. doi: 10.1002/1878-0261.13542

PMCID:: PMC10850799

Abstract Article PDF–1.1M

Select item 1078147512.

Macrophage-specific deletion of Notch-1 induced M2 anti-inflammatory effect in atherosclerosis via activation of the PI3K-oxidative stress axis

Mingming Zhang, Xiangyong Yue, Xueping Zhao, Yonggang Lu, Hongtao Liu, Zhe Zhang, Huan Ma, Xing Wang, Hanying Xing

Aging (Albany NY) 2023 Dec 31; 15(24): 15196–15212. Published online 2023 Dec 26. doi: 10.18632/aging.205342

PMCID:: PMC10781475

Abstract Article PDF–1.5M

Select item 1076117913.

A SNAI2/CTCF Interaction is Required for NOTCH1 Expression in Rhabdomyosarcoma

Prethish Sreenivas, Long Wang, Meng Wang, Anil Challa, Paulomi Modi, Nicole Rae Hensch, Berkley Gryder, Hsien-Chao Chou, Xiang R. Zhao, Benjamin Sunkel, Rodrigo Moreno-Campos, Javed Khan, Benjamin Z. Stanton, Myron S. Ignatius

Mol Cell Biol. 2023; 43(11): 547–565. Published online 2023 Nov 17. doi: 10.1080/10985549.2023.2256640

PMCID:: PMC10761179

Abstract Article PDF–2.7M

Select item 1069212914.

The Notch1 signaling pathway directly modulates the human RANKL-induced osteoclastogenesis

Costanzo Padovano, Salvatore Daniele Bianco, Francesca Sansico, Elisabetta De Santis, Francesco Tamiro, Mattia Colucci, Beatrice Totti, Serena Di Iasio, Gaja Bruno, Patrizio Panelli, Giuseppe Miscio, Tommaso Mazza, Vincenzo Giambra

Sci Rep. 2023; 13: 21199. Published online 2023 Dec 1. doi: 10.1038/s41598-023-48615-2

PMCID:: PMC10692129

Abstract Article PDF–5.2M

Select item 1055588715.

Notch1 cortical signaling regulates epithelial architecture and cell–cell adhesion

Matthew J. White, Kyle A. Jacobs, Tania Singh, Lakyn N. Mayo, Annie Lin, Christopher S. Chen, Young-wook Jun, Matthew L. Kutys

J Cell Biol. 2023 Dec 4; 222(12): e202303013. Published online 2023 Oct 5. doi: 10.1083/jcb.202303013

PMCID:: PMC10555887

Abstract Article PDF–7.6M

Select item 1050377816.

VEGFR3 is required for button junction formation in lymphatic vessels

Melanie Jannaway, Drishya Iyer, Diandra M. Mastrogiacomo, Kunyu Li, Derek C. Sung, Ying Yang, Mark L. Kahn, Joshua P. Scallan

Cell Rep. Author manuscript; available in PMC 2023 Sep 15.

Published in final edited form as: Cell Rep. 2023 Jul 25; 42(7): 112777. Published online 2023 Jul 16. doi: 10.1016/j.celrep.2023.112777

PMCID:: PMC10503778

Abstract Article PDF–1.5M

Select item 1047653417.

Deletion of osteopontin in non-small cell lung cancer cells affects bone metabolism by regulating miR-34c/Notch1 axis: a clue to bone metastasis

Jing Guo, Chang-Yong Tong, Jian-Guang Shi, Xin-Jian Li, Xue-Qin Chen

Eur J Histochem. 2023 Jul 26; 67(3): 3631. Published online 2023 Jul 26. doi: 10.4081/ejh.2023.3631

PMCID:: PMC10476534

Abstract Article PDF–18M

Select item 1028411718.

Exploring an Alternative Cysteine-Reactive Chemistry to Enable Proteome-Wide PPI Analysis by Cross-Linking Mass Spectrometry

Fenglong Jiao, Leah J. Salituro, Clinton Yu, Craig B. Gutierrez, Scott D. Rychnovsky, Lan Huang

Anal Chem. Author manuscript; available in PMC 2023 Jun 21.

Published in final edited form as: Anal Chem. 2023 Jan 31; 95(4): 2532–2539. Published online 2023 Jan 18. doi: 10.1021/acs.analchem.2c04986

PMCID:: PMC10284117

Abstract Article PDF–2.5M

Select item 1023742219.

TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing

Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan

Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233

PMCID:: PMC10237422

Abstract Article PDF–23M

Select item 1018582420.

Inhibition of the intracellular domain of Notch1 results in vascular endothelial cell dysfunction in sepsis

Tingyan Liu, Caiyan Zhang, Jiayun Ying, Yaodong Wang, Gangfeng Yan, Yufeng Zhou, Guoping Lu

Front Immunol. 2023; 14: 1134556. Published online 2023 May 2. doi: 10.3389/fimmu.2023.1134556

PMCID:: PMC10185824

Abstract Article PDF–27M

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