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Select item 102374221.

TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing

Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan

Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233

PMCID:: PMC10237422

Abstract Article PDF–23M

Select item 83641812.

Protein interaction landscapes revealed by advanced in vivo cross-linking–mass spectrometry

Andrew Wheat, Clinton Yu, Xiaorong Wang, Anthony M. Burke, Ilan E. Chemmama, Robyn M. Kaake, Peter Baker, Scott D. Rychnovsky, Jing Yang, Lan Huang

Proc Natl Acad Sci U S A. 2021 Aug 10; 118(32): e2023360118. Published online 2021 Aug 4. doi: 10.1073/pnas.2023360118

PMCID:: PMC8364181

Abstract Article PDF–3.0M

Select item 81650303.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 80459324.

A novel p53 regulator, C16ORF72/TAPR1, buffers against telomerase inhibition

Yahya Benslimane, María Sánchez‐Osuna, Jasmin Coulombe‐Huntington, Thierry Bertomeu, Danielle Henry, Caroline Huard, Éric Bonneil, Pierre Thibault, Mike Tyers, Lea Harrington

Aging Cell. 2021 Apr; 20(4): e13331. Published online 2021 Mar 4. doi: 10.1111/acel.13331

PMCID:: PMC8045932

Abstract Article PDF–1.9M

Select item 72951795.

Biochemical Reduction of the Topology of the Diverse WDR76 Protein Interactome

Gerald Dayebgadoh, Mihaela E. Sardiu, Laurence Florens, Michael P. Washburn

J Proteome Res. Author manuscript; available in PMC 2020 Jun 15.

Published in final edited form as: J Proteome Res. 2019 Sep 6; 18(9): 3479–3491. Published online 2019 Aug 9. doi: 10.1021/acs.jproteome.9b00373

PMCID:: PMC7295179

Abstract Article PDF–2.6M

Select item 62982546.

A protein-protein interaction map of the TNF-induced NF-κB signal transduction pathway

Emmy Van Quickelberghe, Delphine De Sutter, Geert van Loo, Sven Eyckerman, Kris Gevaert

Sci Data. 2018; 5: 180289. Published online 2018 Dec 18. doi: 10.1038/sdata.2018.289

PMCID:: PMC6298254

Abstract Article PDF–1.4M

Select item 62516127.

A homozygous mutation p.Arg2167Trp in FREM2 causes isolated cryptophthalmos

Qian Yu, Bingying Lin, Shangqian Xie, Song Gao, Wei Li, Yizhi Liu, Hongwei Wang, Danping Huang, Zhi Xie

Hum Mol Genet. 2018 Jul 1; 27(13): 2357–2366. Published online 2018 Apr 24. doi: 10.1093/hmg/ddy144

PMCID:: PMC6251612

Abstract Article PDF–806K

Select item 61666828.

Histone Interaction Landscapes Visualized by Crosslinking Mass Spectrometry in Intact Cell Nuclei

Domenico Fasci, Hugo van Ingen, Richard A. Scheltema, Albert J. R. Heck

Mol Cell Proteomics. 2018 Oct; 17(10): 2018–2033. Published online 2018 Jul 18. doi: 10.1074/mcp.RA118.000924

PMCID:: PMC6166682

Abstract Article PDF–3.8M

Select item 59857209.

The role of FREM2 and FRAS1 in the development of congenital diaphragmatic hernia

Valerie K Jordan, Tyler F Beck, Andres Hernandez-Garcia, Peter N Kundert, Bum-Jun Kim, Shalini N Jhangiani, Tomasz Gambin, Molly Starkovich, Jaya Punetha, Ingrid S Paine, Jennifer E Posey, Alexander H Li, Donna Muzny, Chih-Wei Hsu, Amber J Lashua, Xin Sun, Caraciolo J Fernandes, Mary E Dickinson, Kevin P Lally, Richard A Gibbs, Eric Boerwinkle, James R Lupski, Daryl A Scott

Hum Mol Genet. 2018 Jun 15; 27(12): 2064–2075. Published online 2018 Mar 28. doi: 10.1093/hmg/ddy110

PMCID:: PMC5985720

Abstract Article PDF–810K

Select item 598364210.

Meta-Analysis and Experimental Validation Identified FREM2 and SPRY1 as New Glioblastoma Marker Candidates

Marko Vidak, Ivana Jovcevska, Neja Samec, Alja Zottel, Mirjana Liovic, Damjana Rozman, Saso Dzeroski, Peter Juvan, Radovan Komel

Int J Mol Sci. 2018 May; 19(5): 1369. Published online 2018 May 4. doi: 10.3390/ijms19051369

PMCID:: PMC5983642

Abstract Article PDF–9.3M

Select item 553161111.

Architecture of the human interactome defines protein communities and disease networks

Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper

Nature. Author manuscript; available in PMC 2017 Nov 17.

Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366

PMCID:: PMC5531611

Abstract Article PDF–2.7M

Select item 461721112.

The BioPlex Network: A Systematic Exploration of the Human Interactome

Edward L. Huttlin, Lily Ting, Raphael J. Bruckner, Fana Gebreab, Melanie P. Gygi, John Szpyt, Stanley Tam, Gabriela Zarraga, Greg Colby, Kurt Baltier, Rui Dong, Virginia Guarani, Laura Pontano Vaites, Alban Ordureau, Ramin Rad, Brian K. Erickson, Martin Wühr, Joel Chick, Bo Zhai, Deepak Kolippakkam, Julian Mintseris, Robert A. Obar, Tim Harris, Spyros Artavanis-Tsakonas, Mathew E. Sowa, Pietro DeCamilli, Joao A. Paulo, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2016 Jul 16.

Published in final edited form as: Cell. 2015 Jul 16; 162(2): 425–440. doi: 10.1016/j.cell.2015.06.043

PMCID:: PMC4617211

Abstract Article PDF–2.2M

Select item 414798613.

Mild Recessive Mutations in Six Fraser Syndrome–Related Genes Cause Isolated Congenital Anomalies of the Kidney and Urinary Tract

Stefan Kohl, Daw-Yang Hwang, Gabriel C. Dworschak, Alina C. Hilger, Pawaree Saisawat, Asaf Vivante, Natasa Stajic, Radovan Bogdanovic, Heiko M. Reutter, Elijah O. Kehinde, Velibor Tasic, Friedhelm Hildebrandt

J Am Soc Nephrol. 2014 Sep; 25(9): 1917–1922. Published online 2014 Apr 3. doi: 10.1681/ASN.2013101103

PMCID:: PMC4147986

Abstract Article

Select item 383601214.

Identification of two novel CAKUT-causing genes by massively parallel exon resequencing of candidate genes in patients with unilateral renal agenesis

Pawaree Saisawat, Velibor Tasic, Virginia Vega-Warner, Elijah O. Kehinde, Barbara Günther, Rannar Airik, Jeffrey W. Innis, Bethan E. Hoskins, Julia Hoefele, Edgar A. Otto, Friedhelm Hildebrandt

Kidney Int. Author manuscript; available in PMC 2013 Nov 21.

Published in final edited form as: Kidney Int. 2012 Jan; 81(2): 10.1038/ki.2011.315. Published online 2011 Sep 7. doi: 10.1038/ki.2011.315

PMCID:: PMC3836012

Abstract Article PDF–1.0M

Select item 377350515.

In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine

Simona Principe, E. Ellen Jones, Yunee Kim, Ankit Sinha, Julius O. Nyalwidhe, Jasmin Brooks, O. John Semmes, Dean A. Troyer, Raymond S. Lance, Thomas Kislinger, Richard R. Drake

Proteomics. Author manuscript; available in PMC 2014 May 1.

Published in final edited form as: Proteomics. 2013 May; 13(0): 1667–1671. Published online 2013 Apr 23. doi: 10.1002/pmic.201200561

PMCID:: PMC3773505

Abstract Article PDF–630K

Select item 334314516.

Differential Gene Expression in the Adrenals of Normal and Anencephalic Fetuses and Studies Focused on the Fras-1-Related Extracellular Matrix Protein (FREM2) Gene

Christine W. Mansfield, Bruce R. Carr, Ona M. Faye-Petersen, Dongquan Chen, Yewei Xing, William E. Rainey, C. Richard Parker, Jr

Reprod Sci. 2011 Nov; 18(11): 1146–1153. doi: 10.1177/1933719111408113

PMCID:: PMC3343145

Abstract Article PDF–292K

Select item 317805917.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 317112318.

Mindbomb 1, an E3 ubiquitin ligase, forms a complex with RYK to activate Wnt/β-catenin signaling

Jason D. Berndt, Atsushi Aoyagi, Peitzu Yang, Jamie N. Anastas, Lan Tang, Randall T. Moon

J Cell Biol. 2011 Sep 5; 194(5): 737–750. doi: 10.1083/jcb.201107021

PMCID:: PMC3171123

Abstract Article PDF–3.3M

Select item 266528819.

The DNA sequence and analysis of human chromosome 13

A. Dunham, L. H. Matthews, J. Burton, J. L. Ashurst, K. L. Howe, K. J. Ashcroft, D. M. Beare, D. C. Burford, S. E. Hunt, S. Griffiths-Jones, M. C. Jones, S. J. Keenan, K. Oliver, C. E. Scott, R. Ainscough, J. P. Almeida, K. D. Ambrose, D. T. Andrews, R. I. S. Ashwell, A. K. Babbage, C. L. Bagguley, J. Bailey, R. Bannerjee, K. F. Barlow, K. Bates, H. Beasley, C. P. Bird, S. Bray-Allen, A. J. Brown, J. Y. Brown, W. Burrill, C. Carder, N. P. Carter, J. C. Chapman, M. E. Clamp, S. Y. Clark, G. Clarke, C. M. Clee, S. C. M. Clegg, V. Cobley, J. E. Collins, N. Corby, G. J. Coville, P. Deloukas, P. Dhami, I. Dunham, M. Dunn, M. E. Earthrowl, A. G. Ellington, L. Faulkner, A. G. Frankish, J. Frankland, L. French, P. Garner, J. Garnett, J. G. R. Gilbert, C. J. Gilson, J. Ghori, D. V. Grafham, S. M. Gribble, C. Griffiths, R. E. Hall, S. Hammond, J. L. Harley, E. A. Hart, P. D. Heath, P. J. Howden, E. J. Huckle, P. J. Hunt, A. R. Hunt, C. Johnson, D. Johnson, M. Kay, A. M. Kimberley, A. King, G. K. Laird, C. J. Langford, S. Lawlor, D. A. Leongamornlert, D. M. Lloyd, C. Lloyd, J. E. Loveland, J. Lovell, S. Martin, M. Mashreghi-Mohammadi, S. J. McLaren, A. McMurray, S. Milne, M. J. F. Moore, T. Nickerson, S. A. Palmer, A. V. Pearce, A. I. Peck, S. Pelan, B. Phillimore, K. M. Porter, C. M. Rice, S. Searle, H. K. Sehra, R. Shownkeen, C. D. Skuce, M. Smith, C. A. Steward, N. Sycamore, J. Tester, D. W. Thomas, A. Tracey, A. Tromans, B. Tubby, M. Wall, J. M. Wallis, A. P. West, S. L. Whitehead, D. L. Willey, L. Wilming, P. W. Wray, M. W. Wright, L. Young, A. Coulson, R. Durbin, T. Hubbard, J. E. Sulston, S. Beck, D. R. Bentley, J. Rogers, M. T. Ross

Nature. Author manuscript; available in PMC 2009 Apr 5.

Published in final edited form as: Nature. 2004 Apr 1; 428(6982): 522–528. doi: 10.1038/nature02379

PMCID:: PMC2665288

Abstract Article PDF–1.2M

Select item 185094320.

Human Plasma N-Glycoproteome Analysis by Immunoaffinity Subtraction, Hydrazide Chemistry, and Mass Spectrometry

Tao Liu, Wei-Jun Qian, Marina A. Gritsenko, David G. Camp, II, Matthew E. Monroe, Ronald J. Moore, Richard D. Smith

J Proteome Res. Author manuscript; available in PMC 2007 Apr 10.

Published in final edited form as: J Proteome Res. 2005; 4(6): 2070–2080. doi: 10.1021/pr0502065

PMCID:: PMC1850943

Abstract Article PDF–626K

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