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Select item 68893301.

Cathepsin L induced PC-12 cell apoptosis via activation of B-Myb and regulation of cell cycle proteins

Xiao Shen, Yi-fan Zhao, Shu-qing Xu, Long Wang, Hui-min Cao, Ying Cao, Ying Zhu, Yan Wang, Zhong-qin Liang

Acta Pharmacol Sin. 2019 Nov; 40(11): 1394–1403. Published online 2019 Aug 23. doi: 10.1038/s41401-019-0286-9

PMCID:: PMC6889330

Abstract Article PDF–2.4M

Select item 62625052.

Expression of Cathepsin L and Its Intrinsic Inhibitors in Glomeruli of Rats With Puromycin Aminonucleoside Nephrosis

Ayano Kubo, Isao Shirato, Teruo Hidaka, Miyuki Takagi, Yu Sasaki, Katsuhiko Asanuma, Kazumi Ishidoh, Yusuke Suzuki

J Histochem Cytochem. 2018 Dec; 66(12): 863–877. Published online 2018 Jul 27. doi: 10.1369/0022155418791822

PMCID:: PMC6262505

Abstract Article PDF–1.8M

Select item 55694953.

Lysosomal processing of progranulin

Xiaolai Zhou, Daniel H. Paushter, Tuancheng Feng, Lirong Sun, Thomas Reinheckel, Fenghua Hu

Mol Neurodegener. 2017; 12: 62. Published online 2017 Aug 23. doi: 10.1186/s13024-017-0205-9

PMCID:: PMC5569495

Abstract Article PDF–1.0M

Select item 55262454.

The lysosomal protein cathepsin L is a progranulin protease

Chris W. Lee, Jeannette N. Stankowski, Jeannie Chew, Casey N. Cook, Ying-Wai Lam, Sandra Almeida, Yari Carlomagno, Kwok-Fai Lau, Mercedes Prudencio, Fen-Biao Gao, Matthew Bogyo, Dennis W. Dickson, Leonard Petrucelli

Mol Neurodegener. 2017; 12: 55. Published online 2017 Jul 25. doi: 10.1186/s13024-017-0196-6

PMCID:: PMC5526245

Abstract Article PDF–2.4M

Select item 53699555.

Sub-lethal oxidative stress induces lysosome biogenesis via a lysosomal membrane permeabilization-cathepsin-caspase 3-transcription factor EB-dependent pathway

San Min Leow, Shu Xian Serene Chua, Gireedhar Venkatachalam, Liang Shen, Le Luo, Marie-Veronique Clement

Oncotarget. 2017 Mar 7; 8(10): 16170–16189. Published online 2016 Dec 18. doi: 10.18632/oncotarget.14016

PMCID:: PMC5369955

Abstract Article PDF–11M

Select item 44928976.

Cathepsins in Rotator Cuff Tendinopathy: Identification in Human Chronic Tears and Temporal Induction in a Rat Model

Song P. Seto, Akia N. Parks, Yongzhi Qiu, Louis J. Soslowsky, Spero Karas, Manu O. Platt, Johnna S. Temenoff

Ann Biomed Eng. Author manuscript; available in PMC 2016 Sep 1.

Published in final edited form as: Ann Biomed Eng. 2015 Sep; 43(9): 2036–2046. Published online 2015 Jan 6. doi: 10.1007/s10439-014-1245-8

PMCID:: PMC4492897

Abstract Article PDF–979K

Select item 42508177.

Effect of vitamin E and human placenta cysteine peptidase inhibitor on expression of cathepsins B and L in implanted hepatoma Morris 5123 tumor model in Wistar rats

Tadeusz Sebzda, Piotr Hanczyc, Yousif Saleh, Bernice F Akinpelumi, Maciej Siewinski, Jerzy Rudnicki

World J Gastroenterol. 2005 Jan 28; 11(4): 587–592. Published online 2005 Jan 28. doi: 10.3748/wjg.v11.i4.587

PMCID:: PMC4250817

Abstract Article PDF–308K

Select item 40413438.

Cathepsin S is Activated During Colitis and Causes Visceral Hyperalgesia by a PAR₂-dependent Mechanism in Mice

Fiore Cattaruzza, Victoria Lyo, Ella Jones, David Pham, James Hawkins, Kimberley Kirkwood, Eduardo Valdez-Morales, Charles Ibeakanma, Stephen J. Vanner, Matthew Bogyo, Nigel W. Bunnett

Gastroenterology. Author manuscript; available in PMC 2014 Jun 2.

Published in final edited form as: Gastroenterology. 2011 Nov; 141(5): 1864–74.e1-3. Published online 2011 Jul 28. doi: 10.1053/j.gastro.2011.07.035

PMCID:: PMC4041343

Abstract Article PDF–1.5M

Select item 38786069.

Effects of Cathepsin B and L Inhibition on Postischemic Protein Alterations in the Brain

John Anagli, Kadija Abounit, Paul Stemmer, Yuxia Han, Lisa Allred, Shantel Weinsheimer, Ashkhen Movsisyan, Donald Seyfried

Biochem Biophys Res Commun. Author manuscript; available in PMC 2014 Jan 2.

Published in final edited form as: Biochem Biophys Res Commun. 2008 Feb 1; 366(1): 10.1016/j.bbrc.2007.11.104. Published online 2007 Dec 3. doi: 10.1016/j.bbrc.2007.11.104

PMCID:: PMC3878606

Abstract Article PDF–944K

Select item 377350510.

In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine

Simona Principe, E. Ellen Jones, Yunee Kim, Ankit Sinha, Julius O. Nyalwidhe, Jasmin Brooks, O. John Semmes, Dean A. Troyer, Raymond S. Lance, Thomas Kislinger, Richard R. Drake

Proteomics. Author manuscript; available in PMC 2014 May 1.

Published in final edited form as: Proteomics. 2013 May; 13(0): 1667–1671. Published online 2013 Apr 23. doi: 10.1002/pmic.201200561

PMCID:: PMC3773505

Abstract Article PDF–630K

Select item 350153811.

Novel odors affect gene expression for cytokines and proteinases in the rat amygdala and hippocampus

Louis N. Irwin, Donna M. Byers

Brain Res. Author manuscript; available in PMC 2013 Dec 13.

Published in final edited form as: Brain Res. 2012 Dec 13; 1489: 1–7. Published online 2012 Oct 26. doi: 10.1016/j.brainres.2012.10.034

PMCID:: PMC3501538

Abstract Article PDF–1.6M

Select item 342948912.

Cleavage of Nidogen-1 by Cathepsin S Impairs Its Binding to Basement Membrane Partners

Juliette Sage, Emmanuelle Leblanc-Noblesse, Carine Nizard, Takako Sasaki, Sylvianne Schnebert, Eric Perrier, Robin Kurfurst, Dieter Brömme, Gilles Lalmanach, Fabien Lecaille

PLoS One. 2012; 7(8): e43494. Published online 2012 Aug 28. doi: 10.1371/journal.pone.0043494

PMCID:: PMC3429489

Abstract Article PDF–2.0M

Select item 319547813.

CD2AP in mouse and human podocytes controls a proteolytic program that regulates cytoskeletal structure and cellular survival

Suma Yaddanapudi, Mehmet M. Altintas, Andreas D. Kistler, Isabel Fernandez, Clemens C. Möller, Changli Wei, Vasil Peev, Jan B. Flesche, Anna-Lena Forst, Jing Li, Jaakko Patrakka, Zhijie Xiao, Florian Grahammer, Mario Schiffer, Tobias Lohmüller, Thomas Reinheckel, Changkyu Gu, Tobias B. Huber, Wenjun Ju, Markus Bitzer, Maria P. Rastaldi, Phillip Ruiz, Karl Tryggvason, Andrey S. Shaw, Christian Faul, Sanja Sever, Jochen Reiser

J Clin Invest. 2011 Oct 3; 121(10): 3965–3980. Published online 2011 Sep 12. doi: 10.1172/JCI58552

Correction in:: J Clin Invest. 2012 Feb 1; 122(2): 780.

PMCID:: PMC3195478

Abstract Article PDF–2.5M

Select item 317805914.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 310531315.

Structural basis for the recognition and cleavage of histone H3 by cathepsin L

Melanie A. Adams-Cioaba, Joanne C. Krupa, Chao Xu, John S. Mort, Jinrong Min

Nat Commun. 2011 Feb 15; 2: 197. Published online 2011 Feb 15. doi: 10.1038/ncomms1204

PMCID:: PMC3105313

Abstract Article PDF–646K

Select item 282967416.

Lipotoxicity Mediated Cell Dysfunction and Death Involves Lysosomal Membrane Permeabilization and Cathepsin L Activity

Frankis G. Almaguel, Jo-Wen Liu, Fabio J. Pacheco, Daisy De Leon, Carlos A. Casiano, Marino De Leon

Brain Res. Author manuscript; available in PMC 2011 Mar 8.

Published in final edited form as: Brain Res. 2010 Mar 8; 1318C: 133–143. Published online 2010 Jan 4. doi: 10.1016/j.brainres.2009.12.038

PMCID:: PMC2829674

Abstract Article PDF–1.8M

Select item 282204417.

Roles for Catharsis S, L, and B in Insulitis and Diabetes in the NOD Mouse

Lianne C. Hsing, Elizabeth A. Kirk, Timothy S. McMillen, Shuo-Hung Hsiao, Mark Caldwell, Barbara Houston, Alexander Y. Rudensky, Renee C. LeBoeuf

J Autoimmun. Author manuscript; available in PMC 2011 Mar 1.

Published in final edited form as: J Autoimmun. 2010 Mar; 34(2): 96. Published online 2009 Aug 6. doi: 10.1016/j.jaut.2009.07.003

PMCID:: PMC2822044

Abstract Article PDF–2.6M

Select item 276919418.

Impaired autophagic flux mediates acinar cell vacuole formation and trypsinogen activation in rodent models of acute pancreatitis

Olga A. Mareninova, Kip Hermann, Samuel W. French, Mark S. O’Konski, Stephen J. Pandol, Paul Webster, Ann H. Erickson, Nobuhiko Katunuma, Fred S. Gorelick, Ilya Gukovsky, Anna S. Gukovskaya

J Clin Invest. 2009 Nov 2; 119(11): 3340–3355. Published online 2009 Oct 1. doi: 10.1172/JCI38674