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Select item 109332671.

Interaction network of human early embryonic transcription factors

Lisa Gawriyski, Zenglai Tan, Xiaonan Liu, Iftekhar Chowdhury, Dicle Malaymar Pinar, Qin Zhang, Jere Weltner, Eeva-Mari Jouhilahti, Gong-Hong Wei, Juha Kere, Markku Varjosalo

EMBO Rep. 2024 Mar; 25(3): 1589–1622. Published online 2024 Jan 31. doi: 10.1038/s44319-024-00074-0

PMCID:: PMC10933267

Abstract Article PDF–2.9M

Select item 105658762.

Pulse-SILAC and Interactomics Reveal Distinct DDB1-CUL4–Associated Factors, Cellular Functions, and Protein Substrates

Jennifer Raisch, Marie-Line Dubois, Marika Groleau, Dominique Lévesque, Thomas Burger, Carla-Marie Jurkovic, Romain Brailly, Gwendoline Marbach, Alyson McKenna, Catherine Barrette, Pierre-Étienne Jacques, François-Michel Boisvert

Mol Cell Proteomics. 2023 Oct; 22(10): 100644. Published online 2023 Sep 7. doi: 10.1016/j.mcpro.2023.100644

PMCID:: PMC10565876

Abstract Article PDF–3.7M

Select item 97080863.

The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers

Martina Oravcová, Minghua Nie, Nicola Zilio, Shintaro Maeda, Yasaman Jami-Alahmadi, Eros Lazzerini-Denchi, James A Wohlschlegel, Helle D Ulrich, Takanori Otomo, Michael N Boddy

eLife. 2022; 11: e79676. Published online 2022 Nov 14. doi: 10.7554/eLife.79676

PMCID:: PMC9708086

Abstract Article PDF–8.5M

Select item 95699554.

A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation

Yulemi Gonzalez Quesada, Luc DesGroseillers

Int J Mol Sci. 2022 Oct; 23(19): 11588. Published online 2022 Sep 30. doi: 10.3390/ijms231911588

PMCID:: PMC9569955

Abstract Article PDF–2.1M

Select item 95403455.

The in vivo Interaction Landscape of Histones H3.1 and H3.3

Robert Siddaway, Scott Milos, Étienne Coyaud, Hwa Young Yun, Shahir M. Morcos, Sanja Pajovic, Eric I. Campos, Brian Raught, Cynthia Hawkins

Mol Cell Proteomics. 2022 Oct; 21(10): 100411. Published online 2022 Sep 9. doi: 10.1016/j.mcpro.2022.100411

PMCID:: PMC9540345

Abstract Article PDF–3.9M

Select item 95076996.

Homeobox B9 Promotes the Progression of Hepatocellular Carcinoma via TGF-β1/Smad and ERK1/2 Signaling Pathways

Lizhi Bai, Pan Ge, Yanni Zhang, Yi Song, Rong Xing, Dangxia Zhou

Biomed Res Int. 2022; 2022: 1080315. Published online 2022 Sep 16. doi: 10.1155/2022/1080315

PMCID:: PMC9507699

Abstract Article PDF–6.0M

Select item 91322607.

HOXB9 mediates resistance to chemotherapy and patient outcomes through the TGFβ pathway in pancreatic cancer

Naokazu Chiba, Shigeto Ochiai, Takahiro Gunji, Toshimichi Kobayashi, Toru Sano, Koichi Tomita, Shigeyuki Kawachi

Oncotarget. 2022; 13: 747–754. Published online 2022 May 25. doi: 10.18632/oncotarget.28235

PMCID:: PMC9132260

Abstract Article PDF–2.6M

Select item 91197368.

OpenCell: proteome-scale endogenous tagging enables the cartography of human cellular organization

Nathan H. Cho, Keith C. Cheveralls, Andreas-David Brunner, Kibeom Kim, André C. Michaelis, Preethi Raghavan, Hirofumi Kobayashi, Laura Savy, Jason Y. Li, Hera Canaj, James Y.S. Kim, Edna M. Stewart, Christian Gnann, Frank McCarthy, Joana P. Cabrera, Rachel M. Brunetti, Bryant B. Chhun, Greg Dingle, Marco Y. Hein, Bo Huang, Shalin B. Mehta, Jonathan S. Weissman, Rafael Gómez-Sjöberg, Daniel N. Itzhak, Loic A. Royer, Matthias Mann, Manuel D. Leonetti

Science. Author manuscript; available in PMC 2022 Sep 11.

Published in final edited form as: Science. 2022 Mar 11; 375(6585): eabi6983. Published online 2022 Mar 11. doi: 10.1126/science.abi6983

PMCID:: PMC9119736

Abstract Article PDF–3.3M

Select item 88798399.

HOXB9 Overexpression Promotes Colorectal Cancer Progression and Is Associated with Worse Survival in Liver Resection Patients for Colorectal Liver Metastases

Eirini Martinou, Carla Moller-Levet, Dimitrios Karamanis, Izhar Bagwan, Angeliki M. Angelidi

Int J Mol Sci. 2022 Feb; 23(4): 2281. Published online 2022 Feb 18. doi: 10.3390/ijms23042281

PMCID:: PMC8879839

Abstract Article PDF–2.7M

Select item 882889510.

Human transcription factor protein interaction networks

Helka Göös, Matias Kinnunen, Kari Salokas, Zenglai Tan, Xiaonan Liu, Leena Yadav, Qin Zhang, Gong-Hong Wei, Markku Varjosalo

Nat Commun. 2022; 13: 766. Published online 2022 Feb 9. doi: 10.1038/s41467-022-28341-5

PMCID:: PMC8828895

Abstract Article PDF–1.7M

Select item 870725311.

A Systematic Review on HOX Genes as Potential Biomarkers in Colorectal Cancer: An Emerging Role of HOXB9

Eirini Martinou, Giulia Falgari, Izhar Bagwan, Angeliki M. Angelidi

Int J Mol Sci. 2021 Dec; 22(24): 13429. Published online 2021 Dec 14. doi: 10.3390/ijms222413429

PMCID:: PMC8707253

Abstract Article PDF–1.4M

Select item 847653312.

Insights into homeobox B9: a propeller for metastasis in dormant prostate cancer progenitor cells

Yi Sui, Wei Hu, Wei Zhang, Dejian Li, Hongbo Zhu, Qinghua You, Rujian Zhu, Qingtong Yi, Tao Tang, Lili Gao, Shengjuan Zhu, Tao Yang

Br J Cancer. 2021 Sep 28; 125(7): 1003–1015. Published online 2021 Jul 10. doi: 10.1038/s41416-021-01482-y

PMCID:: PMC8476533

Abstract Article PDF–2.8M

Select item 816503013.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 814079814.

Genome-Wide Epigenetic Landscape of Lung Adenocarcinoma Links HOXB9 DNA Methylation to Intrinsic EGFR-TKI Resistance and Heterogeneous Responses

Sheng-Fang Su, Chia-Hsin Liu, Chiou-Ling Cheng, Chao-Chi Ho, Tsung-Ying Yang, Kun-Chieh Chen, Kuo-Hsuan Hsu, Jeng-Sen Tseng, Huei-Wen Chen, Gee-Chen Chang, Sung-Liang Yu, Ker-Chau Li

JCO Precis Oncol. 2021; 5: PO.20.00151. Published online 2021 Feb 19. doi: 10.1200/PO.20.00151

PMCID:: PMC8140798

Abstract Article PDF–809K

Select item 800904815.

Impact of cytosine methylation on DNA binding specificities of human transcription factors

Yimeng Yin, Ekaterina Morgunova, Arttu Jolma, Eevi Kaasinen, Biswajyoti Sahu, Syed Khund-Sayeed, Pratyush K. Das, Teemu Kivioja, Kashyap Dave, Fan Zhong, Kazuhiro R. Nitta, Minna Taipale, Alexander Popov, Paul A. Ginno, Silvia Domcke, Jian Yan, Dirk Schübeler, Charles Vinson, Jussi Taipale

Science. Author manuscript; available in PMC 2021 Mar 30.

Published in final edited form as: Science. 2017 May 5; 356(6337): eaaj2239. doi: 10.1126/science.aaj2239

PMCID:: PMC8009048

Abstract Article PDF–2.6M

Select item 795024816.

HOXB9 enhances the ability of lung cancer cells to penetrate the blood-brain barrier

HongShan Zheng, ChenLong Li, ZhenZhe Li, KaiBin Zhu, HongBo Bao, JinSheng Xiong, Peng Liang

Aging (Albany NY) 2021 Feb 28; 13(4): 4999–5019. Published online 2020 Dec 19. doi: 10.18632/aging.202324

PMCID:: PMC7950248

Abstract Article PDF–2.3M

Select item 788479617.

HOX genes promote cell proliferation and are potential therapeutic targets in adrenocortical tumours

Jeffrey C. Francis, Jennifer R. Gardiner, Yoan Renaud, Ritika Chauhan, Yacob Weinstein, Celso Gomez-Sanchez, Anne-Marie Lefrançois-Martinez, Jérôme Bertherat, Pierre Val, Amanda Swain

Br J Cancer. 2021 Feb 16; 124(4): 805–816. Published online 2020 Nov 20. doi: 10.1038/s41416-020-01166-z

PMCID:: PMC7884796

Abstract Article PDF–6.9M

Select item 724327718.

Homeobox B9 integrates bone morphogenic protein 4 with inflammation at atheroprone sites

Celine Souilhol, Ismael Gauci, Shuang Feng, Blanca Tardajos Ayllon, Marwa Mahmoud, Lindsay Canham, Maria Fragiadaki, Jovana Serbanovic-Canic, Victoria Ridger, Paul Charles Evans

Cardiovasc Res. 2020 Jun 1; 116(7): 1300–1310. Published online 2019 Aug 29. doi: 10.1093/cvr/cvz235

PMCID:: PMC7243277

Abstract Article PDF–1.4M

Select item 716998319.

A reference map of the human binary protein interactome

Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood

Nature. Author manuscript; available in PMC 2020 Oct 8.

Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x

PMCID:: PMC7169983

Abstract Article PDF–5.4M

Select item 707759020.

Mutually exclusive antiproliferative effect of cell line‐specific HOX inhibition in epithelial ovarian cancer cell lines: SKOV‐3 vs RMUG‐S

Miseon Kim, Dong Hoon Suh, Jin Young Choi, Seul Lee, Jae Ryul Bae, Kidong Kim, Jae Hong No, Yong Beom Kim

J Cell Mol Med. 2020 Mar; 24(5): 3246–3251. Published online 2020 Jan 22. doi: 10.1111/jcmm.14993

PMCID:: PMC7077590

Abstract Article PDF–1.0M

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