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Items: 1 to 20 of 242

1.
TRIM21 and Fc-engineered antibodies: decoding its complex antibody binding mode with implications for viral neutralization
Johannes Reusch, Linda Elise Franken, Jakob Then, Philippe Ringler, Joachim Butzer, Thomas Juroschek, Christian Klein, Tilman Schlothauer, Laurent Larivière
Front Immunol. 2024; 15: 1401471. Published online 2024 Jun 12. doi: 10.3389/fimmu.2024.1401471
PMCID:
PMC11210195
AbstractArticlePDF–7.5M
2.
Presence of serum tripartite motif‐containing 21 antibodies in patients with esophageal squamous cell carcinoma
Mari Kuboshima, Hideaki Shimada, Tian‐Ling Liu, Fumio Nomura, Masaki Takiguchi, Takaki Hiwasa, Takenori Ochiai
Cancer Sci. 2006 May; 97(5): 380–386. Published online 2006 Apr 10. doi: 10.1111/j.1349-7006.2006.00192.x
PMCID:
PMC11158984
AbstractArticlePDF–454K
3.
TRIM21 is critical in regulating hepatocellular carcinoma growth and response to therapy by altering the MST1/YAP pathway
Bo Shu, Yingxia Zhou, Guoqiong Lei, Yu Peng, Cong Ding, Zhuan Li, Chao He
Cancer Sci. 2024 May; 115(5): 1476–1491. Published online 2024 Mar 12. doi: 10.1111/cas.16134
PMCID:
PMC11093211
AbstractArticlePDF–5.7M
4.
The deubiquitinase USP7 and E3 ligase TRIM21 regulate vasculogenic mimicry and malignant progression of RMS by balancing SNAI2 homeostasis
Ruyue Zhang, Daidi Zhang, Fugen Han, Xiaorui Song, Yaodong Zhang, Jie Zhang, Qingwen Zhu, Yanru Qin
J Exp Clin Cancer Res. 2024; 43: 135. Published online 2024 May 4. doi: 10.1186/s13046-024-03056-1
PMCID:
PMC11069146
AbstractArticlePDF–11M
5.
TRIM21 Promotes Oxidative Stress and Ferroptosis through the SQSTM1-NRF2-KEAP1 Axis to Increase the Titers of H5N1 Highly Pathogenic Avian Influenza Virus
Yifan Wei, Yongxia Gu, Ziwei Zhou, Changrong Wu, Yanwei Liu, Hailiang Sun
Int J Mol Sci. 2024 Mar; 25(6): 3315. Published online 2024 Mar 14. doi: 10.3390/ijms25063315
PMCID:
PMC10970474
AbstractArticlePDF–4.2M
6.
FGF19 promotes nasopharyngeal carcinoma progression by inducing angiogenesis via inhibiting TRIM21-mediated ANXA2 ubiquitination
Si Shi, Qicheng Zhang, Kaiwen Zhang, Wenhui Chen, Haijing Xie, Si Pan, Ziyi Xue, Bo You, Jianmei Zhao, Yiwen You
Cell Oncol (Dordr) 2024; 47(1): 283–301. Published online 2023 Oct 2. doi: 10.1007/s13402-023-00868-9
PMCID:
PMC10899426
AbstractArticlePDF–14M
7.
Systems genetics of influenza A virus-infected mice identifies TRIM21 as a critical regulator of pulmonary innate immune response
Zhuoyuan Alex Li, Akhilesh Kumar Bajpai, Ruixue Wang, Yaxin Liu, Richard J. Webby, Esther Wilk, Weikuan Gu, Klaus Schughart, Kui Li, Lu Lu
Virus Res. 2024 Apr; 342: 199335. Published online 2024 Feb 17. doi: 10.1016/j.virusres.2024.199335
PMCID:
PMC10882161
AbstractArticlePDF–4.7M
8.
TRIM28-mediated nucleocapsid protein SUMOylation enhances SARS-CoV-2 virulence
Jiang Ren, Shuai Wang, Zhi Zong, Ting Pan, Sijia Liu, Wei Mao, Huizhe Huang, Xiaohua Yan, Bing Yang, Xin He, Fangfang Zhou, Long Zhang
Nat Commun. 2024; 15: 244. Published online 2024 Jan 4. doi: 10.1038/s41467-023-44502-6
PMCID:
PMC10764958
AbstractArticlePDF–4.4M
9.
N6-methyladenosine modification of OIP5-AS1 promotes glycolysis, tumorigenesis, and metastasis of gastric cancer by inhibiting Trim21-mediated hnRNPA1 ubiquitination and degradation
Rongjun Xie, Longfei Liu, Xianzhou Lu, Chengjian He, Hongyi Yao, Guoxin Li
Gastric Cancer. 2024; 27(1): 49–71. Published online 2023 Oct 28. doi: 10.1007/s10120-023-01437-7
PMCID:
PMC10761432
AbstractArticlePDF–22M
10.
Inflammation-induced TRIM21 represses hepatic steatosis by promoting the ubiquitination of lipogenic regulators
Kostas C. Nikolaou, Svenja Godbersen, Muthiah Manoharan, Stefan Wieland, Markus H. Heim, Markus Stoffel
JCI Insight. 2023 Nov 8; 8(21): e164694. Published online 2023 Nov 8. doi: 10.1172/jci.insight.164694
PMCID:
PMC10721265
AbstractArticlePDF–2.5M
11.
The midnolin-proteasome pathway catches proteins for ubiquitination-independent degradation
Xin Gu, Christopher Nardone, Nolan Kamitaki, Aoyue Mao, Stephen J. Elledge, Michael E. Greenberg
Science. Author manuscript; available in PMC 2023 Oct 31.
Published in final edited form as: Science. 2023 Aug 25; 381(6660): eadh5021. Published online 2023 Aug 25. doi: 10.1126/science.adh5021
PMCID:
PMC10617673
AbstractArticlePDF–3.6M
12.
Trim21 depletion alleviates bone loss in osteoporosis via activation of YAP1/β-catenin signaling
Ri-Xu Liu, Rong-He Gu, Zhi-Peng Li, Zhi-Quan Hao, Qin-Xiao Hu, Zhen-Yan Li, Xiao-Gang Wang, Wang Tang, Xiao-He Wang, Yu-Kai Zeng, Zhen-Wei Li, Qiu Dong, Xiao-Feng Zhu, Di Chen, Ke-Wei Zhao, Rong-Hua Zhang, Zhen-Gang Zha, Huan-Tian Zhang
Bone Res. 2023; 11: 56. Published online 2023 Oct 26. doi: 10.1038/s41413-023-00296-3
PMCID:
PMC10603047
AbstractArticlePDF–11M
13.
TRIM21‐Promoted FSP1 Plasma Membrane Translocation Confers Ferroptosis Resistance in Human Cancers
Jun Gong, Yuhui Liu, Wenjia Wang, Ruizhi He, Qilong Xia, Lin Chen, Chunle Zhao, Yang Gao, Yongkang Shi, Yu Bai, Yangwei Liao, Qi Zhang, Feng Zhu, Min Wang, Xu Li, Renyi Qin
Adv Sci (Weinh) 2023 Oct; 10(29): 2302318. Published online 2023 Aug 16. doi: 10.1002/advs.202302318
PMCID:
PMC10582465
AbstractArticlePDF–8.3M
14.
Targeting VPS72 inhibits ACTL6A/MYC axis activity in HCC progression
Furong Liu, Zhibin Liao, Lu Qin, Ze Zhang, Qiaofeng Zhang, Shenqi Han, Weifeng Zeng, Hongwei Zhang, Yachong Liu, Jia Song, Wei Chen, He Zhu, Huifang Liang, Xiaoping Chen, Bixiang Zhang, Zhanguo Zhang
Hepatology. 2023 Nov; 78(5): 1384–1401. Published online 2023 Jan 13. doi: 10.1097/HEP.0000000000000268
PMCID:
PMC10581431
AbstractArticlePDF–2.2M
15.
TRIM21 enhances bortezomib sensitivity in multiple myeloma by halting prosurvival autophagy
Jing Chen, Wen Cao, Xi Huang, Qingxiao Chen, Shuting Ye, Jianwei Qu, Yang Liu, Xing Guo, Shunnan Yao, Enfan Zhang, Jingsong He, Anqi Li, Li Yang, Zhen Cai
Blood Adv. 2023 Oct 10; 7(19): 5752–5770. Published online 2023 Apr 24. doi: 10.1182/bloodadvances.2022008241
PMCID:
PMC10561007
AbstractArticlePDF–9.0M
16.
USP25 promotes hepatocellular carcinoma progression by interacting with TRIM21 via the Wnt/β-catenin signaling pathway
Yinghui Liu, Jingjing Ma, Shimin Lu, Pengzhan He, Weiguo Dong
Chin Med J (Engl) 2023 Sep 20; 136(18): 2229–2242. Published online 2023 Jul 13. doi: 10.1097/CM9.0000000000002714
PMCID:
PMC10508383
AbstractArticlePDF–37M
17.
TRIM21-dependent target protein ubiquitination mediates cell-free Trim-Away
Tycho E.T. Mevissen, Anisa V. Prasad, Johannes C. Walter
Cell Rep. Author manuscript; available in PMC 2023 Oct 23.
Published in final edited form as: Cell Rep. 2023 Feb 28; 42(2): 112125. Published online 2023 Feb 18. doi: 10.1016/j.celrep.2023.112125
PMCID:
PMC10435667
AbstractArticlePDF–2.3M
18.
Regulation of hPCL3 isoforms’ ubiquitination by TRIM21 in non-small cell lung cancer progression
Ye Xu, Wenhong Liu, Xiawei Jiang, Junfeng Li, Qingling Liu, Fang Su, Shanming Ruan, Zhiqian Zhang, Fangfang Tao
Life Sci Alliance. 2023 Oct; 6(10): e202302060. Published online 2023 Jul 28. doi: 10.26508/lsa.202302060
PMCID:
PMC10387491
AbstractArticlePDF–3.3M
19.
BCKDK regulates breast cancer cell adhesion and tumor metastasis by inhibiting TRIM21 ubiquitinate talin1
Chunlan Xu, Kunao Yang, Zuodong Xuan, Jinxin Li, Yankuo Liu, Yue Zhao, Zeyuan Zheng, Yang Bai, Zhiyuan Shi, Chen Shao, Lei Zhang, Huimin Sun
Cell Death Dis. 2023 Jul; 14(7): 445. Published online 2023 Jul 17. doi: 10.1038/s41419-023-05944-4
PMCID:
PMC10352378
AbstractArticlePDF–4.1M
20.
UBE2S interacting with TRIM21 mediates the K11-linked ubiquitination of LPP to promote the lymphatic metastasis of bladder cancer
Kanghua Xiao, Shengmeng Peng, Junlin Lu, Ting Zhou, Xuwei Hong, Siting Chen, Guangyao Liu, Hong Li, Jian Huang, Xu Chen, Tianxin Lin
Cell Death Dis. 2023 Jul; 14(7): 408. Published online 2023 Jul 8. doi: 10.1038/s41419-023-05938-2
PMCID:
PMC10329682
AbstractArticlePDF–20M

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