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Select item 100729061.

Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity

Martin Golkowski, Andrea Lius, Tanmay Sapre, Ho-Tak Lau, Taylor Moreno, Dustin J. Maly, Shao-En Ong

Mol Cell. Author manuscript; available in PMC 2023 Apr 4.

Published in final edited form as: Mol Cell. 2023 Mar 2; 83(5): 803–818.e8. Published online 2023 Feb 2. doi: 10.1016/j.molcel.2023.01.015

PMCID:: PMC10072906

Abstract Article PDF–4.2M

Select item 91197362.

OpenCell: proteome-scale endogenous tagging enables the cartography of human cellular organization

Nathan H. Cho, Keith C. Cheveralls, Andreas-David Brunner, Kibeom Kim, André C. Michaelis, Preethi Raghavan, Hirofumi Kobayashi, Laura Savy, Jason Y. Li, Hera Canaj, James Y.S. Kim, Edna M. Stewart, Christian Gnann, Frank McCarthy, Joana P. Cabrera, Rachel M. Brunetti, Bryant B. Chhun, Greg Dingle, Marco Y. Hein, Bo Huang, Shalin B. Mehta, Jonathan S. Weissman, Rafael Gómez-Sjöberg, Daniel N. Itzhak, Loic A. Royer, Matthias Mann, Manuel D. Leonetti

Science. Author manuscript; available in PMC 2022 Sep 11.

Published in final edited form as: Science. 2022 Mar 11; 375(6585): eabi6983. Published online 2022 Mar 11. doi: 10.1126/science.abi6983

PMCID:: PMC9119736

Abstract Article PDF–3.3M

Select item 88970223.

Histone deacetylase inhibitors inhibit cervical cancer growth through Parkin acetylation-mediated mitophagy

Xin Sun, Yuhan Shu, Guiqin Ye, Caixia Wu, Mengting Xu, Ruilan Gao, Dongsheng Huang, Jianbin Zhang

Acta Pharm Sin B. 2022 Feb; 12(2): 838–852. Published online 2021 Jul 21. doi: 10.1016/j.apsb.2021.07.003

PMCID:: PMC8897022

Abstract Article PDF–3.0M

Select item 88421654.

CFTR interactome mapping using the mammalian membrane two‐hybrid high‐throughput screening system

Sang Hyun Lim, Jamie Snider, Liron Birimberg‐Schwartz, Wan Ip, Joana C Serralha, Hugo M Botelho, Miquéias Lopes‐Pacheco, Madalena C Pinto, Mohamed Taha Moutaoufik, Mara Zilocchi, Onofrio Laselva, Mohsen Esmaeili, Max Kotlyar, Anna Lyakisheva, Priscilla Tang, Lucía López Vázquez, Indira Akula, Farzaneh Aboualizadeh, Victoria Wong, Ingrid Grozavu, Teuta Opacak‐Bernardi, Zhong Yao, Meg Mendoza, Mohan Babu, Igor Jurisica, Tanja Gonska, Christine E Bear, Margarida D Amaral, Igor Stagljar

Mol Syst Biol. 2022 Feb; 18(2): e10629. Published online 2022 Feb 14. doi: 10.15252/msb.202110629

PMCID:: PMC8842165

Abstract Article PDF–3.0M

Select item 82641815.

Polymorphism rs7214723 in CAMKK1: a new genetic variant associated with cardiovascular diseases

Sofia Beghi, Francesca Cavaliere, Matteo Manfredini, Sandro Ferrarese, Claudio Corazzari, Cesare Beghi, Annamaria Buschini

Biosci Rep. 2021 Jul 30; 41(7): BSR20210326. Published online 2021 Jul 6. doi: 10.1042/BSR20210326

PMCID:: PMC8264181

Abstract Article PDF–1.0M

Select item 81650306.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 78737017.

Global proteomics of Ubqln2-based murine models of ALS

Alexandra M. Whiteley, Miguel A. Prado, Stefanie A.H. de Poot, Joao A. Paulo, Marissa Ashton, Sara Dominguez, Martin Weber, Hai Ngu, John Szpyt, Mark P. Jedrychowski, Amy Easton, Steven P. Gygi, Thimo Kurz, Mervyn J. Monteiro, Eric J. Brown, Daniel Finley

J Biol Chem. 2021 Jan-Jun; 296: 100153. Published online 2020 Dec 10. doi: 10.1074/jbc.RA120.015960

PMCID:: PMC7873701

Abstract Article PDF–3.0M

Select item 74273278.

Kinase Interaction Network Expands Functional and Disease Roles of Human Kinases

Marija Buljan, Rodolfo Ciuffa, Audrey van Drogen, Anton Vichalkovski, Martin Mehnert, George Rosenberger, Sohyon Lee, Markku Varjosalo, Lucia Espona Pernas, Vincent Spegg, Berend Snijder, Ruedi Aebersold, Matthias Gstaiger

Mol Cell. 2020 Aug 6; 79(3): 504–520.e9. doi: 10.1016/j.molcel.2020.07.001

PMCID:: PMC7427327

Abstract Article

Select item 55316119.

Architecture of the human interactome defines protein communities and disease networks

Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper

Nature. Author manuscript; available in PMC 2017 Nov 17.

Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366

PMCID:: PMC5531611

Abstract Article PDF–2.7M

Select item 491946210.

Differential AMP-activated Protein Kinase (AMPK) Recognition Mechanism of Ca²⁺/Calmodulin-dependent Protein Kinase Kinase Isoforms

Yuya Fujiwara, Yoshinori Kawaguchi, Tomohito Fujimoto, Naoki Kanayama, Masaki Magari, Hiroshi Tokumitsu

J Biol Chem. 2016 Jun 24; 291(26): 13802–13808. Published online 2016 May 5. doi: 10.1074/jbc.M116.727867

PMCID:: PMC4919462

Abstract Article PDF–1.3M

Select item 439875811.

Role of Ca²⁺/Calmodulin-Dependent Protein Kinase Kinase in Adrenal Aldosterone Production

Kazutaka Nanba, Andrew Chen, Koshiro Nishimoto, William E. Rainey

Endocrinology. 2015 May; 156(5): 1750–1756. Published online 2015 Feb 13. doi: 10.1210/en.2014-1782

PMCID:: PMC4398758

Abstract Article

Select item 389478612.

Quantitative Analysis of Hsp90-Client Interactions Reveals Principles of Substrate Recognition

Mikko Taipale, Irina Krykbaeva, Martina Koeva, Can Kayatekin, Kenneth D. Westover, Georgios I. Karras, Susan Lindquist

Cell. Author manuscript; available in PMC 2014 Jan 17.

Published in final edited form as: Cell. 2012 Aug 31; 150(5): 987–1001. doi: 10.1016/j.cell.2012.06.047

PMCID:: PMC3894786

Abstract Article PDF–5.0M

Select item 319082613.

Interactions of Pathological Hallmark Proteins: TUBULIN POLYMERIZATION PROMOTING PROTEIN/p25, β-AMYLOID, AND α-SYNUCLEIN

Judit Oláh, Orsolya Vincze, Dezső Virók, Dóra Simon, Zsolt Bozsó, Natália Tőkési, István Horváth, Emma Hlavanda, János Kovács, Anna Magyar, Mária Szűcs, Ferenc Orosz, Botond Penke, Judit Ovádi

J Biol Chem. 2011 Sep 30; 286(39): 34088–34100. Published online 2011 Aug 8. doi: 10.1074/jbc.M111.243907

PMCID:: PMC3190826

Abstract Article PDF–5.7M

Select item 317805914.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 289380015.

A Large-scale genetic association study of esophageal adenocarcinoma risk

Chen-yu Liu, Michael C. Wu, Feng Chen, Monica Ter-Minassian, Kofi Asomaning, Rihong Zhai, Zhaoxi Wang, Li Su, Rebecca S. Heist, Matthew H. Kulke, Xihong Lin, Geoffrey Liu, David C. Christiani

Carcinogenesis. 2010 Jul; 31(7): 1259–1263. Published online 2010 May 7. doi: 10.1093/carcin/bgq092

PMCID:: PMC2893800

Abstract Article PDF–84K

Select item 284709016.

International Lung Cancer Consortium: Coordinated association study of 10 potential lung cancer susceptibility variants

Therese Truong, Wiebke Sauter, James D. McKay, H.Dean Hosgood, III, Carla Gallagher, Christopher I. Amos, Margaret Spitz, Joshua Muscat, Philip Lazarus, Thomas Illig, H.Erich Wichmann, Heike Bickeböller, Angela Risch, Hendrik Dienemann, Zuo-Feng Zhang, Behnaz Pezeshki Naeim, Ping Yang, Shanbeh Zienolddiny, Aage Haugen, Loïc Le Marchand, Yun-Chul Hong, Jin Hee Kim, Eric J. Duell, Angeline S. Andrew, Chikako Kiyohara, Hongbing Shen, Keitaro Matsuo, Takeshi Suzuki, Adeline Seow, Daniel P.K. Ng, Qing Lan, David Zaridze, Neonilia Szeszenia-Dabrowska, Jolanta Lissowska, Peter Rudnai, Eleonora Fabianova, Vali Constantinescu, Vladimir Bencko, Lenka Foretova, Vladimir Janout, Neil E. Caporaso, Demetrius Albanes, Michael Thun, Maria Teresa Landi, Joanna Trubicka, Marcin Lener, Jan Lubiński, Ying Wang, Amélie Chabrier, Paolo Boffetta, Paul Brennan, Rayjean J. Hung, EPIC-lung

Carcinogenesis. 2010 Apr; 31(4): 625–633. Published online 2010 Jan 27. doi: 10.1093/carcin/bgq001

PMCID:: PMC2847090

Abstract Article PDF–150K

Select item 275596417.

Adiponectin Activates AMP-activated Protein Kinase in Muscle Cells via APPL1/LKB1-dependent and Phospholipase C/Ca²⁺/Ca²⁺/Calmodulin-dependent Protein Kinase Kinase-dependent Pathways

Lijun Zhou, Sathyaseelan S. Deepa, Julie C. Etzler, Jiyoon Ryu, Xuming Mao, Qichen Fang, Dianna D. Liu, Jesus M. Torres, Weiping Jia, James D. Lechleiter, Feng Liu, Lily Q. Dong

J Biol Chem. 2009 Aug 14; 284(33): 22426–22435. Published online 2009 Jun 11. doi: 10.1074/jbc.M109.028357

PMCID:: PMC2755964

Abstract Article PDF–1.9M

Select item 264481718.

Genome-Wide and Candidate Gene Association Study of Cigarette Smoking Behaviors

Neil Caporaso, Fangyi Gu, Nilanjan Chatterjee, Jin Sheng-Chih, Kai Yu, Meredith Yeager, Constance Chen, Kevin Jacobs, William Wheeler, Maria Teresa Landi, Regina G. Ziegler, David J. Hunter, Stephen Chanock, Susan Hankinson, Peter Kraft, Andrew W. Bergen

PLoS One. 2009; 4(2): e4653. Published online 2009 Feb 27. doi: 10.1371/journal.pone.0004653

PMCID:: PMC2644817

Abstract Article PDF–739K

Select item 250014119.

CaM kinase Iα–induced phosphorylation of Drp1 regulates mitochondrial morphology

Xiao-Jian Han, Yun-Fei Lu, Shun-Ai Li, Taku Kaitsuka, Yasufumi Sato, Kazuhito Tomizawa, Angus C. Nairn, Kohji Takei, Hideki Matsui, Masayuki Matsushita

J Cell Biol. 2008 Aug 11; 182(3): 573–585. doi: 10.1083/jcb.200802164

PMCID:: PMC2500141

Abstract Article PDF–4.6M

Select item 222965020.

Ca²⁺/Calmodulin-Dependent Kinase Kinase α Is Expressed by Monocytic Cells and Regulates the Activation Profile

Christopher B. Guest, Eric L. Deszo, Matthew E. Hartman, Jason M. York, Keith W. Kelley, Gregory G. Freund

PLoS One. 2008; 3(2): e1606. Published online 2008 Feb 13. doi: 10.1371/journal.pone.0001606

PMCID:: PMC2229650

Abstract Article PDF–331K

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