PMC Links for GEO Profiles (Select 109398052) - PMC

Select item 83529641.

Integrative oncogene-dependency mapping identifies RIT1 vulnerabilities and synergies in lung cancer

Athea Vichas, Amanda K. Riley, Naomi T. Nkinsi, Shriya Kamlapurkar, Phoebe C. R. Parrish, April Lo, Fujiko Duke, Jennifer Chen, Iris Fung, Jacqueline Watson, Matthew Rees, Austin M. Gabel, James D. Thomas, Robert K. Bradley, John K. Lee, Emily M. Hatch, Marina K. Baine, Natasha Rekhtman, Marc Ladanyi, Federica Piccioni, Alice H. Berger

Nat Commun. 2021; 12: 4789. Published online 2021 Aug 9. doi: 10.1038/s41467-021-24841-y

PMCID:: PMC8352964

Abstract Article PDF–4.5M

Select item 81650302.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 71699833.

A reference map of the human binary protein interactome

Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood

Nature. Author manuscript; available in PMC 2020 Oct 8.

Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x

PMCID:: PMC7169983

Abstract Article PDF–5.4M

Select item 60777224.

Estrogen-regulated feedback loop limits the efficacy of estrogen receptor–targeted breast cancer therapy

Tengfei Xiao, Wei Li, Xiaoqing Wang, Han Xu, Jixin Yang, Qiu Wu, Ying Huang, Joseph Geradts, Peng Jiang, Teng Fei, David Chi, Chongzhi Zang, Qi Liao, Jonathan Rennhack, Eran Andrechek, Nanlin Li, Simone Detre, Mitchell Dowsett, Rinath M. Jeselsohn, X. Shirley Liu, Myles Brown

Proc Natl Acad Sci U S A. 2018 Jul 31; 115(31): 7869–7878. Published online 2018 Jul 9. doi: 10.1073/pnas.1722617115

PMCID:: PMC6077722

Abstract Article PDF–2.4M

Select item 55008155.

Gene duplication and neo-functionalization in the evolutionary and functional divergence of the metazoan copper transporters Ctr1 and Ctr2

Brandon L. Logeman, L. Kent Wood, Jaekwon Lee, Dennis J. Thiele

J Biol Chem. 2017 Jul 7; 292(27): 11531–11546. Published online 2017 May 15. doi: 10.1074/jbc.M117.793356

PMCID:: PMC5500815

Abstract Article PDF–3.6M

Select item 54152356.

The Identification of Novel Proteins That Interact With the GLP-1 Receptor and Restrain its Activity

X. Huang, F. F. Dai, G. Gaisano, K. Giglou, J. Han, M. Zhang, S. Kittanakom, V. Wong, L. Wei, A. D. Showalter, K. W. Sloop, I. Stagljar, M. B. Wheeler

Mol Endocrinol. September 1, 2013; 27(9): 1550–1563. Published online 2013 Jul 17. doi: 10.1210/me.2013-1047

PMCID:: PMC5415235

Abstract Article

Select item 53717307.

Systematic protein–protein interaction mapping for clinically relevant human GPCRs

Kate Sokolina, Saranya Kittanakom, Jamie Snider, Max Kotlyar, Pascal Maurice, Jorge Gandía, Abla Benleulmi‐Chaachoua, Kenjiro Tadagaki, Atsuro Oishi, Victoria Wong, Ramy H Malty, Viktor Deineko, Hiroyuki Aoki, Shahreen Amin, Zhong Yao, Xavier Morató, David Otasek, Hiroyuki Kobayashi, Javier Menendez, Daniel Auerbach, Stephane Angers, Natasa Pržulj, Michel Bouvier, Mohan Babu, Francisco Ciruela, Ralf Jockers, Igor Jurisica, Igor Stagljar

Mol Syst Biol. 2017 Mar; 13(3): 918. Published online 2017 Mar 15. doi: 10.15252/msb.20167430

PMCID:: PMC5371730

Abstract Article PDF–4.1M

Select item 46350458.

The Copper Transporter 1 (CTR1) is Required to Maintain the Stability of Copper Transporter 2 (CTR2)

Cheng-Yu Tsai, Janika K. Liebig, Igor F. Tsigelny, Stephen B. Howell

Metallomics. Author manuscript; available in PMC 2015 Nov 5.

Published in final edited form as: Metallomics. 2015 Nov 4; 7(11): 1477–1487. Published online 2015 Jul 24. doi: 10.1039/c5mt00131e

PMCID:: PMC4635045

Abstract Article PDF–1.6M

Select item 41752759.

The Role of Ctr1 and Ctr2 in Mammalian Copper Homeostasis and Platinum-based Chemotherapy

Helena Öhrvik, Dennis J. Thiele

J Trace Elem Med Biol. Author manuscript; available in PMC 2016 Jul 1.

Published in final edited form as: J Trace Elem Med Biol. 2015 Jul; 31: 178–182. Published online 2014 Mar 24. doi: 10.1016/j.jtemb.2014.03.006

PMCID:: PMC4175275

Abstract Article PDF–617K

Select item 398259710.

Copper Transporter 2 Regulates Intracellular Copper and Sensitivity to Cisplatin

Carlos P. Huang, Mariama Fofana, Jefferson Chan, Christopher J. Chang, Stephen B. Howell

Metallomics. Author manuscript; available in PMC 2015 Mar 26.

Published in final edited form as: Metallomics. 2014 Mar; 6(3): 654–661. Published online 2014 Feb 13. doi: 10.1039/c3mt00331k

PMCID:: PMC3982597

Abstract Article PDF–2.2M

Select item 352423911.

Brain Transcriptome-Wide Screen for HIV-1 Nef Protein Interaction Partners Reveals Various Membrane-Associated Proteins

Ellen C. Kammula, Jessica Mötter, Alexandra Gorgels, Esther Jonas, Silke Hoffmann, Dieter Willbold

PLoS One. 2012; 7(12): e51578. Published online 2012 Dec 17. doi: 10.1371/journal.pone.0051578

PMCID:: PMC3524239

Abstract Article PDF–705K

Select item 317805912.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 286264013.

Copper Transporter 2 Regulates the Cellular Accumulation and Cytotoxicity of Cisplatin and Carboplatin

Brian G. Blair, Christopher A. Larson, Roohangiz Safaei, Stephen B. Howell

Clin Cancer Res. Author manuscript; available in PMC 2010 Jul 1.

Published in final edited form as: Clin Cancer Res. 2009 Jul 1; 15(13): 4312–4321. Published online 2009 Jun 9. doi: 10.1158/1078-0432.CCR-09-0311

PMCID:: PMC2862640

Abstract Article PDF–1.2M

Select item 226740014.

Human copper transporter 2 is localized in late endosomes and lysosomes and facilitates cellular copper uptake

Peter V. E. vandenBerghe, Dineke E. Folmer, Helga E. M. Malingré, Ellen vanBeurden, Adriana E. M. Klomp, Bart vandeSluis, Maarten Merkx, Ruud Berger, Leo W. J. Klomp

Biochem J. 2007 Oct 1; 407(Pt 1): 49–59. Prepublished online 2007 Jul 6. Published online 2007 Sep 12. doi: 10.1042/BJ20070705