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Items: 1 to 20 of 151

1.
Deciphering the role of FUS::DDIT3 expression and tumor microenvironment in myxoid liposarcoma development
Parmida Ranji, Emma Jonasson, Lisa Andersson, Stefan Filges, Manuel Luna Santamaría, Christoffer Vannas, Soheila Dolatabadi, Anna Gustafsson, Ola Myklebost, Joakim Håkansson, Henrik Fagman, Göran Landberg, Pierre Åman, Anders Ståhlberg
J Transl Med. 2024; 22: 389. Published online 2024 Apr 26. doi: 10.1186/s12967-024-05211-w
PMCID:
PMC11046918
AbstractArticlePDF–2.1M
2.
C/EBPα-p30 confers AML cell susceptibility to the terminal unfolded protein response and resistance to Venetoclax by activating DDIT3 transcription
Mengbao Du, Mowang Wang, Meng Liu, Shan Fu, Yu Lin, Yankun Huo, Jian Yu, Xiaohong Yu, Chong Wang, Haowen Xiao, Limengmeng Wang
J Exp Clin Cancer Res. 2024; 43: 79. Published online 2024 Mar 13. doi: 10.1186/s13046-024-02975-3
PMCID:
PMC10936103
AbstractArticlePDF–7.2M
3.
Integrated Bioinformatics Analysis Identified ASNS and DDIT3 as the Therapeutic Target in Castrate-Resistant Prostate Cancer
Ae Ryang Jung, Sun Shin, Mee Young Kim, U-Syn Ha, Sung-Hoo Hong, Ji Youl Lee, Sae Woong Kim, Yeun-Jun Chung, Yong Hyun Park
Int J Mol Sci. 2024 Mar; 25(5): 2836. Published online 2024 Feb 29. doi: 10.3390/ijms25052836
PMCID:
PMC10932076
AbstractArticlePDF–24M
4.
CHOP upregulation and dysregulation of the mature form of the SNAT2 amino acid transporter in the placentas from small for gestational age newborns
Emma Barroso, Marta Díaz, Ana Cristina Reguera, Mona Peyman, Jesús Balsinde, Javier Jurado-Aguilar, Meijian Zhang, Adel Rostami, Xavier Palomer, Lourdes Ibáñez, Manuel Vázquez-Carrera
Cell Commun Signal. 2023; 21: 326. Published online 2023 Nov 13. doi: 10.1186/s12964-023-01352-5
PMCID:
PMC10644500
AbstractArticlePDF–2.5M
5.
Endoplasmic Reticulum Stress Promotes the Expression of TNF-α in THP-1 Cells by Mechanisms Involving ROS/CHOP/HIF-1α and MAPK/NF-κB Pathways
Nadeem Akhter, Ajit Wilson, Hossein Arefanian, Reeby Thomas, Shihab Kochumon, Fatema Al-Rashed, Mohamed Abu-Farha, Ashraf Al-Madhoun, Fahd Al-Mulla, Rasheed Ahmad, Sardar Sindhu
Int J Mol Sci. 2023 Oct; 24(20): 15186. Published online 2023 Oct 14. doi: 10.3390/ijms242015186
PMCID:
PMC10606873
AbstractArticlePDF–5.2M
6.
AI-guided pipeline for protein-protein interaction drug discovery identifies a SARS-CoV-2 inhibitor
Philipp Trepte, Christopher Secker, Simona Kostova, Sibusiso B. Maseko, Soon Gang Choi, Jeremy Blavier, Igor Minia, Eduardo Silva Ramos, Patricia Cassonnet, Sabrina Golusik, Martina Zenkner, Stephanie Beetz, Mara J. Liebich, Nadine Scharek, Anja Schütz, Marcel Sperling, Michael Lisurek, Yang Wang, Kerstin Spirohn, Tong Hao, Michael A. Calderwood, David E. Hill, Markus Landthaler, Julien Olivet, Jean-Claude Twizere, Marc Vidal, Erich E. Wanker
Version 1. bioRxiv. Preprint. 2023 Jun 14. doi: 10.1101/2023.06.14.544560
Published in:
Mol Syst Biol. 2024 Apr; 20(4): 428–457.
PMCID:
PMC10312674
AbstractArticlePDF–9.6M
7.
The transcription factor DDIT3 is a potential driver of dyserythropoiesis in myelodysplastic syndromes
Nerea Berastegui, Marina Ainciburu, Juan P. Romero, Paula Garcia-Olloqui, Ana Alfonso-Pierola, Céline Philippe, Amaia Vilas-Zornoza, Patxi San Martin-Uriz, Raquel Ruiz-Hernández, Ander Abarrategi, Raquel Ordoñez, Diego Alignani, Sarai Sarvide, Laura Castro-Labrador, José M. Lamo-Espinosa, Mikel San-Julian, Tamara Jimenez, Félix López-Cadenas, Sandra Muntion, Fermin Sanchez-Guijo, Antonieta Molero, Maria Julia Montoro, Bárbara Tazón, Guillermo Serrano, Aintzane Diaz-Mazkiaran, Mikel Hernaez, Sofía Huerga, Findlay Bewicke-Copley, Ana Rio-Machin, Matthew T. Maurano, María Díez-Campelo, David Valcarcel, Kevin Rouault-Pierre, David Lara-Astiaso, Teresa Ezponda, Felipe Prosper
Nat Commun. 2022; 13: 7619. Published online 2022 Dec 9. doi: 10.1038/s41467-022-35192-7
PMCID:
PMC9734135
AbstractArticlePDF–7.5M
8.
Epigenetic Silencing of CHOP Expression by the Histone Methyltransferase EHMT1 Regulates Apoptosis in Colorectal Cancer Cells
Kwangho Kim, Tae Young Ryu, Jinkwon Lee, Mi-Young Son, Dae-Soo Kim, Sang Kyum Kim, Hyun-Soo Cho
Mol Cells. 2022 Sep 30; 45(9): 622–630. Published online 2022 Jun 24. doi: 10.14348/molcells.2022.0014
PMCID:
PMC9448644
AbstractArticlePDF–3.3M
9.
Riboflavin (Vitamin B2) Deficiency Induces Apoptosis Mediated by Endoplasmic Reticulum Stress and the CHOP Pathway in HepG2 Cells
Bo Zhang, Jun-Ting Cao, Yong-Bao Wu, Ke-Xin Gao, Ming Xie, Zheng-Kui Zhou, Jing Tang, Shui-Sheng Hou
Nutrients. 2022 Aug; 14(16): 3356. Published online 2022 Aug 16. doi: 10.3390/nu14163356
PMCID:
PMC9414855
AbstractArticlePDF–6.8M
10.
Induction of DR5-Dependent Apoptosis by PGA2 through ATF4-CHOP Pathway
Kyeong-Min Park, Ji-Young Park, Jaehyuk Pyo, Sun-Young Lee, Ho-Shik Kim
Molecules. 2022 Jun; 27(12): 3804. Published online 2022 Jun 13. doi: 10.3390/molecules27123804
PMCID:
PMC9230093
AbstractArticlePDF–1.4M
11.
Indeterminate and oncogenic potential: CHIP vs CHOP mutations in AML with NPM1 alteration
Luca Vincenzo Cappelli, Manja Meggendorfer, Constance Baer, Niroshan Nadarajah, Stephan Hutter, Sabine Jeromin, Frank Dicker, Wolfgang Kern, Torsten Haferlach, Claudia Haferlach, Alexander Höllein
Leukemia. 2022; 36(2): 394–402. Published online 2021 Aug 10. doi: 10.1038/s41375-021-01368-1
PMCID:
PMC8807394
AbstractArticlePDF–1.7M
12.
Large scale discovery of coronavirus-host factor protein interaction motifs reveals SARS-CoV-2 specific mechanisms and vulnerabilities
Thomas Kruse, Caroline Benz, Dimitriya H. Garvanska, Richard Lindqvist, Filip Mihalic, Fabian Coscia, Raviteja Inturi, Ahmed Sayadi, Leandro Simonetti, Emma Nilsson, Muhammad Ali, Johanna Kliche, Ainhoa Moliner Morro, Andreas Mund, Eva Andersson, Gerald McInerney, Matthias Mann, Per Jemth, Norman E. Davey, Anna K. Överby, Jakob Nilsson, Ylva Ivarsson
Nat Commun. 2021; 12: 6761. Published online 2021 Nov 19. doi: 10.1038/s41467-021-26498-z
PMCID:
PMC8605023
AbstractArticlePDF–8.0M
13.
The molecular mechanism of GADD153 in apoptosis of keloid fibroblasts exposed to botulinum toxin type A
Ming‐Shiuan Nien, Wen‐Pin Cheng, Jun Feng, Yong‐Yan Cui
J Cell Mol Med. 2021 Oct; 25(19): 9402–9410. Published online 2021 Sep 2. doi: 10.1111/jcmm.16881
PMCID:
PMC8500951
AbstractArticlePDF–910K
14.
Radiation-induced phosphorylation of a prion-like domain regulates transformation by FUS-CHOP
Mark Chen, Joseph P. Foster, II, Ian C. Lock, Nathan H. Leisenring, Andrea R. Daniel, Warren Floyd, Eric Xu, Ian J. Davis, David G. Kirsch
Cancer Res. Author manuscript; available in PMC 2022 Apr 1.
Published in final edited form as: Cancer Res. 2021 Oct 1; 81(19): 4939–4948. Published online 2021 Aug 12. doi: 10.1158/0008-5472.CAN-20-1497
PMCID:
PMC8487964
AbstractArticlePDF–1.2M
15.
QRICH1 Dictates the Outcome of ER Stress through Transcriptional Control of Proteostasis
Kwontae You, Lingfei Wang, Chih-Hung Chou, Kai Liu, Toru Nakata, Alok Jaiswal, Junmei Yao, Ariel Lefkovith, Abdifatah Omar, Jacqueline G. Perrigoue, Jennifer E. Towne, Aviv Regev, Daniel B. Graham, Ramnik J. Xavier
Science. Author manuscript; available in PMC 2021 Jul 27.
Published in final edited form as: Science. 2021 Jan 1; 371(6524): eabb6896. doi: 10.1126/science.abb6896
PMCID:
PMC8315080
AbstractArticlePDF–1.3M
16.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
17.
miR-1283 Contributes to Endoplasmic Reticulum Stress in the Development of Hypertension Through the Activating Transcription Factor-4 (ATF4)/C/EBP-Homologous Protein (CHOP) Signaling Pathway
Weihao Chen, Tianhao Liu, Qiuer Liang, Xudong Chen, Wencong Tao, Meixia Fang, Ya Xiao, Liguo Chen
Med Sci Monit. 2021; 27: e930552-1–e930552-18. Prepublished online 2021 Feb 18. Published online 2021 Apr 29. doi: 10.12659/MSM.930552
PMCID:
PMC8095088
AbstractArticlePDF–1.6M
18.
CHOP Pro-Apoptotic Transcriptional Program in Response to ER Stress Is Hacked by Zika Virus
Jonathan Turpin, Daed El-Safadi, Grégorie Lebeau, Etienne Frumence, Philippe Desprès, Wildriss Viranaïcken, Pascale Krejbich-Trotot
Int J Mol Sci. 2021 Apr; 22(7): 3750. Published online 2021 Apr 3. doi: 10.3390/ijms22073750
PMCID:
PMC8038490
AbstractArticlePDF–2.8M
19.
Molecular and Cellular Effects of Chemical Chaperone—TUDCA on ER-Stressed NHAC-kn Human Articular Chondrocytes Cultured in Normoxic and Hypoxic Conditions
Magdalena Kusaczuk, Monika Naumowicz, Rafał Krętowski, Bartosz Cukierman, Marzanna Cechowska-Pasko
Molecules. 2021 Feb; 26(4): 878. Published online 2021 Feb 7. doi: 10.3390/molecules26040878
PMCID:
PMC7915106
AbstractArticlePDF–4.3M
20.
Omeprazole improves chemosensitivity of gastric cancer cells by m6A demethylase FTO-mediated activation of mTORC1 and DDIT3 up-regulation
Shuitu Feng, Guoqin Qiu, Lihong Yang, Lihua Feng, Xin Fan, Fang Ren, Kaida Huang, Yide Chen
Biosci Rep. 2021 Jan 29; 41(1): BSR20200842. Published online 2021 Jan 27. doi: 10.1042/BSR20200842
PMCID:
PMC7843496
AbstractArticlePDF–1.6M

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