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Items: 1 to 20 of 45

1.
Comparative proximity biotinylation implicates the small GTPase RAB18 in sterol mobilization and biosynthesis
Robert S. Kiss, Jarred Chicoine, Youssef Khalil, Robert Sladek, He Chen, Alessandro Pisaturo, Cyril Martin, Jessica D. Dale, Tegan A. Brudenell, Archith Kamath, Jeffrey Kyei-Boahen, Anouar Hafiane, Girija Daliah, Célia Alecki, Tayah S. Hopes, Martin Heier, Irene A. Aligianis, Jean-Jacques Lebrun, Julie Aspden, Emanuele Paci, Anja Kerksiek, Dieter Lütjohann, Peter Clayton, Jimi C. Wills, Alex von Kriegsheim, Tommy Nilsson, Eamonn Sheridan, Mark T. Handley
J Biol Chem. 2023 Nov; 299(11): 105295. Published online 2023 Sep 28. doi: 10.1016/j.jbc.2023.105295
PMCID:
PMC10641524
AbstractArticlePDF–3.8M
2.
ESYT1 tethers the ER to mitochondria and is required for mitochondrial lipid and calcium homeostasis
Alexandre Janer, Jordan L Morris, Michiel Krols, Hana Antonicka, Mari J Aaltonen, Zhen-Yuan Lin, Hanish Anand, Anne-Claude Gingras, Julien Prudent, Eric A Shoubridge
Life Sci Alliance. 2024 Jan; 7(1): e202302335. Published online 2023 Nov 6. doi: 10.26508/lsa.202302335
PMCID:
PMC10627786
AbstractArticlePDF–5.2M
3.
Elevated FAM134B expression induces radiation-sensitive in hepatocellular carcinoma
Binhui Xie, Yuankang Xie, Cuifu Fang, Baiyin Zhong, Rong Ye, Jianhong Zhang, Qingquan Liu, Heping Li
BMC Cancer. 2023; 23: 671. Published online 2023 Jul 17. doi: 10.1186/s12885-023-11030-x
PMCID:
PMC10353116
AbstractArticlePDF–3.1M
4.
Ubiquitination regulates ER-phagy and remodelling of endoplasmic reticulum
Alexis González, Adriana Covarrubias-Pinto, Ramachandra M. Bhaskara, Marius Glogger, Santosh K. Kuncha, Audrey Xavier, Eric Seemann, Mohit Misra, Marina E. Hoffmann, Bastian Bräuning, Ashwin Balakrishnan, Britta Qualmann, Volker Dötsch, Brenda A. Schulman, Michael M. Kessels, Christian A. Hübner, Mike Heilemann, Gerhard Hummer, Ivan Dikić
Nature. 2023; 618(7964): 394–401. Published online 2023 May 24. doi: 10.1038/s41586-023-06089-2
PMCID:
PMC10247366
AbstractArticlePDF–24M
5.
TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing
Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan
Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233
PMCID:
PMC10237422
AbstractArticlePDF–23M
6.
A regulatory circuit comprising the CBP and SIRT7 regulates FAM134B-mediated ER-phagy
Xinyi Wang, Xiao Jiang, Boran Li, Jiahua Zheng, Jiansheng Guo, Lei Gao, Mengjie Du, Xialian Weng, Lin Li, She Chen, Jingzi Zhang, Lei Fang, Ting Liu, Liang Wang, Wei Liu, Dante Neculai, Qiming Sun
J Cell Biol. 2023 May 1; 222(5): e202201068. Published online 2023 Apr 12. doi: 10.1083/jcb.202201068
PMCID:
PMC10103787
AbstractArticlePDF–6.2M
7.
Assessment of community efforts to advance network-based prediction of protein–protein interactions
Xu-Wen Wang, Lorenzo Madeddu, Kerstin Spirohn, Leonardo Martini, Adriano Fazzone, Luca Becchetti, Thomas P. Wytock, István A. Kovács, Olivér M. Balogh, Bettina Benczik, Mátyás Pétervári, Bence Ágg, Péter Ferdinandy, Loan Vulliard, Jörg Menche, Stefania Colonnese, Manuela Petti, Gaetano Scarano, Francesca Cuomo, Tong Hao, Florent Laval, Luc Willems, Jean-Claude Twizere, Marc Vidal, Michael A. Calderwood, Enrico Petrillo, Albert-László Barabási, Edwin K. Silverman, Joseph Loscalzo, Paola Velardi, Yang-Yu Liu
Nat Commun. 2023; 14: 1582. Published online 2023 Mar 22. doi: 10.1038/s41467-023-37079-7
PMCID:
PMC10033937
AbstractArticlePDF–1.5M
8.
Coronavirus subverts ER-phagy by hijacking FAM134B and ATL3 into p62 condensates to facilitate viral replication
Xuan Tan, Kun Cai, Jiajia Li, Zhen Yuan, Ruifeng Chen, Hurong Xiao, Chuanrui Xu, Bing Hu, Yali Qin, Binbin Ding
Cell Rep. 2023 Apr 25; 42(4): 112286. Published online 2023 Mar 10. doi: 10.1016/j.celrep.2023.112286
PMCID:
PMC9998290
AbstractArticlePDF–7.6M
9.
SARS-CoV-2 ORF3a induces RETREG1/FAM134B-dependent reticulophagy and triggers sequential ER stress and inflammatory responses during SARS-CoV-2 infection
Xiaolin Zhang, Ziwei Yang, Ting Pan, Xubing Long, Qinqin Sun, Pei-Hui Wang, Xiaojuan Li, Ersheng Kuang
Autophagy. 2022; 18(11): 2576–2592. Published online 2022 Mar 3. doi: 10.1080/15548627.2022.2039992
PMCID:
PMC9629087
AbstractArticlePDF–2.4M
10.
Chr21 protein–protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer’s disease
Julia Viard, Yann Loe-Mie, Rachel Daudin, Malik Khelfaoui, Christine Plancon, Anne Boland, Francisco Tejedor, Richard L Huganir, Eunjoon Kim, Makoto Kinoshita, Guofa Liu, Volker Haucke, Thomas Moncion, Eugene Yu, Valérie Hindie, Henri Bléhaut, Clotilde Mircher, Yann Herault, Jean-François Deleuze, Jean-Christophe Rain, Michel Simonneau, Aude-Marie Lepagnol-Bestel
Life Sci Alliance. 2022 Dec; 5(12): e202101205. Published online 2022 Aug 1. doi: 10.26508/lsa.202101205
PMCID:
PMC9348576
AbstractArticlePDF–3.0M
11.
OpenCell: proteome-scale endogenous tagging enables the cartography of human cellular organization
Nathan H. Cho, Keith C. Cheveralls, Andreas-David Brunner, Kibeom Kim, André C. Michaelis, Preethi Raghavan, Hirofumi Kobayashi, Laura Savy, Jason Y. Li, Hera Canaj, James Y.S. Kim, Edna M. Stewart, Christian Gnann, Frank McCarthy, Joana P. Cabrera, Rachel M. Brunetti, Bryant B. Chhun, Greg Dingle, Marco Y. Hein, Bo Huang, Shalin B. Mehta, Jonathan S. Weissman, Rafael Gómez-Sjöberg, Daniel N. Itzhak, Loic A. Royer, Matthias Mann, Manuel D. Leonetti
Science. Author manuscript; available in PMC 2022 Sep 11.
Published in final edited form as: Science. 2022 Mar 11; 375(6585): eabi6983. Published online 2022 Mar 11. doi: 10.1126/science.abi6983
PMCID:
PMC9119736
AbstractArticlePDF–3.3M
12.
C5orf51 is a component of the MON1-CCZ1 complex and controls RAB7A localization and stability during mitophagy
Bing-Ru Yan, Taoyingnan Li, Etienne Coyaud, Estelle M. N. Laurent, Jonathan St-Germain, Yuhuan Zhou, Peter K. Kim, Brian Raught, John H. Brumell
Autophagy. 2022; 18(4): 829–840. Published online 2021 Aug 25. doi: 10.1080/15548627.2021.1960116
PMCID:
PMC9037554
AbstractArticlePDF–4.1M
13.
Genomics Links Inflammation With Neurocognitive Impairment in Children Living With Human Immunodeficiency Virus Type-1
Pratima Rawat, Sean S Brummel, Kumud K Singh, Jihoon Kim, Kelly A Frazer, Sharon Nichols, George R Seage, III, Paige L Williams, Russell B Van Dyke, Olivier Harismendy, Rodney N Trout, Stephen A Spector
J Infect Dis. 2021 Sep 1; 224(5): 870–880. Published online 2020 Dec 29. doi: 10.1093/infdis/jiaa792
PMCID:
PMC8408770
AbstractArticlePDF–2.3M
14.
FAM134B-Mediated ER-phagy Upregulation Attenuates AGEs-Induced Apoptosis and Senescence in Human Nucleus Pulposus Cells
Rongjin Luo, Shuai Li, Gaocai Li, Saideng Lu, Weifeng Zhang, Hui Liu, Jie Lei, Liang Ma, Wencan Ke, Zhiwei Liao, Bingjin Wang, Yu Song, Kun Wang, Yukun Zhang, Cao Yang
Oxid Med Cell Longev. 2021; 2021: 3843145. Published online 2021 Aug 5. doi: 10.1155/2021/3843145
PMCID:
PMC8363461
AbstractArticlePDF–4.0M
15.
RETREG1/FAM134B mediated autophagosomal degradation of AMFR/GP78 and OPA1 —a dual organellar turnover mechanism
Debdatto Mookherjee, Subhrangshu Das, Rukmini Mukherjee, Manindra Bera, Swadhin Chandra Jana, Saikat Chakrabarti, Oishee Chakrabarti
Autophagy. 2021; 17(7): 1729–1752. Published online 2020 Jul 1. doi: 10.1080/15548627.2020.1783118
PMCID:
PMC8354597
AbstractArticlePDF–25M
16.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
17.
Differential expression of full-length and NH2 terminally truncated FAM134B isoforms in normal physiology and cancer
Umur Keles, Evin Iscan, Huriye Erbak Yilmaz, Gökhan Karakülah, Aslı Suner, Erhan Bal, Nilgun Tasdemir, Ayse Derya Cavga, Umut Ekin, Zeynep Mutlu, Sila Kahyaoglu, Muhittin A. Serdar, Nese Atabey, Mehmet Ozturk
Am J Physiol Gastrointest Liver Physiol. 2020 Dec 1; 319(6): G733–G747. Published online 2020 Oct 14. doi: 10.1152/ajpgi.00094.2020
PMCID:
PMC7864244
AbstractArticle
18.
Novel exomic rare variants associated with venous thrombosis
Hiroshi Deguchi, Meenal Shukla, Mohammed Hayat, Ali Torkamani, Darlene J. Elias, John H. Griffin
Br J Haematol. Author manuscript; available in PMC 2020 Dec 11.
Published in final edited form as: Br J Haematol. 2020 Sep; 190(5): 783–786. Published online 2020 Mar 30. doi: 10.1111/bjh.16613
PMCID:
PMC7732677
AbstractArticlePDF–108K
19.
Overexpression of family with sequence similarity 134, member B (FAM134B) in colon cancers and its tumor suppressive properties in vitro
Katherine Ting-Wei Lee, Farhadul Islam, Jelena Vider, Jeremy Martin, Anna Chruścik, Cu-Tai Lu, Vinod Gopalan, Alfred King-yin Lam
Cancer Biol Ther. 2020; 21(10): 954–962. Published online 2020 Aug 28. doi: 10.1080/15384047.2020.1810535
PMCID:
PMC7583494
AbstractArticlePDF–2.1M
20.
MiT/TFE factors control ER‐phagy via transcriptional regulation of FAM134B
Laura Cinque, Chiara De Leonibus, Maria Iavazzo, Natalie Krahmer, Daniela Intartaglia, Francesco Giuseppe Salierno, Rossella De Cegli, Chiara Di Malta, Maria Svelto, Carmela Lanzara, Marianna Maddaluno, Luca Giorgio Wanderlingh, Antje K Huebner, Marcella Cesana, Florian Bonn, Elena Polishchuk, Christian A Hübner, Ivan Conte, Ivan Dikic, Matthias Mann, Andrea Ballabio, Francesca Sacco, Paolo Grumati, Carmine Settembre
EMBO J. 2020 Sep 1; 39(17): e105696. Published online 2020 Jul 27. doi: 10.15252/embj.2020105696
PMCID:
PMC7459426
AbstractArticlePDF–4.1M

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