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Select item 109176601.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 101902892.

Blockade of Activin Receptor IIB Protects Arthritis Pathogenesis by Non‐Amplification of Activin A‐ACVR2B‐NOX4 Axis Pathway

Jimin Jeon, Hyemi Lee, Min‐Seung Jeon, Seok‐Jung Kim, Cham Choi, Ki Woo Kim, Dong Joo Yang, Sangho Lee, Yong‐Soo Bae, Won Il Choi, Juyeon Jung, Seong‐il Eyun, Siyoung Yang

Adv Sci (Weinh) 2023 May; 10(14): 2205161. Published online 2023 Mar 22. doi: 10.1002/advs.202205161

PMCID:: PMC10190289

Abstract Article PDF–5.5M

Select item 99953523.

Functional interaction between Vangl2 and N-cadherin regulates planar cell polarization of the developing neural tube and cochlear sensory epithelium

Tadahiro Nagaoka, Tatsuya Katsuno, Kyoka Fujimura, Kunihiro Tsuchida, Masashi Kishi

Sci Rep. 2023; 13: 3905. Published online 2023 Mar 8. doi: 10.1038/s41598-023-30213-x

PMCID:: PMC9995352

Abstract Article PDF–5.7M

Select item 83799464.

Local versus systemic control of bone and skeletal muscle mass by components of the transforming growth factor-β signaling pathway

Yewei Liu, Adam Lehar, Renata Rydzik, Harshpreet Chandok, Yun-Sil Lee, Daniel W. Youngstrom, Joshy George, Martin M. Matzuk, Emily L. Germain-Lee, Se-Jin Lee

Proc Natl Acad Sci U S A. 2021 Aug 17; 118(33): e2111401118. Published online 2021 Aug 12. doi: 10.1073/pnas.2111401118

PMCID:: PMC8379946

Abstract Article PDF–1.8M

Select item 83132395.

Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development

Francesco Bedogni, Robert F. Hevner

Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034

PMCID:: PMC8313239

Abstract Article PDF–1.6M

Select item 81849386.

Endometrial receptivity and implantation require uterine BMP signaling through an ACVR2A-SMAD1/SMAD5 axis

Diana Monsivais, Takashi Nagashima, Renata Prunskaite-Hyyryläinen, Kaori Nozawa, Keisuke Shimada, Suni Tang, Clark Hamor, Julio E. Agno, Fengju Chen, Ramya P. Masand, Steven L. Young, Chad J. Creighton, Francesco J. DeMayo, Masahito Ikawa, Se-Jin Lee, Martin M. Matzuk

Nat Commun. 2021; 12: 3386. Published online 2021 Jun 7. doi: 10.1038/s41467-021-23571-5

PMCID:: PMC8184938

Abstract Article PDF–18M

Select item 79387707.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Abstract Article PDF–2.0M

Select item 78940558.

Development of a Highly Sensitive ELISA for Measurement of FSH in Serum, Plasma, and Whole Blood in Mice

Luisina Ongaro, Carlos Agustin Isidro Alonso, Xiang Zhou, Emilie Brûlé, Yining Li, Gauthier Schang, Albert F Parlow, Frederik Steyn, Daniel J Bernard

Endocrinology. 2021 Apr; 162(4): bqab014. Published online 2021 Jan 21. doi: 10.1210/endocr/bqab014

PMCID:: PMC7894055

Abstract Article

Select item 75192209.

Targeting myostatin/activin A protects against skeletal muscle and bone loss during spaceflight

Se-Jin Lee, Adam Lehar, Jessica U. Meir, Christina Koch, Andrew Morgan, Lara E. Warren, Renata Rydzik, Daniel W. Youngstrom, Harshpreet Chandok, Joshy George, Joseph Gogain, Michael Michaud, Thomas A. Stoklasek, Yewei Liu, Emily L. Germain-Lee

Proc Natl Acad Sci U S A. 2020 Sep 22; 117(38): 23942–23951. Published online 2020 Sep 8. doi: 10.1073/pnas.2014716117

PMCID:: PMC7519220

Abstract Article PDF–1.2M

Select item 728662110.

Murine FSH Production Depends on the Activin Type II Receptors ACVR2A and ACVR2B

Gauthier Schang, Luisina Ongaro, Hailey Schultz, Ying Wang, Xiang Zhou, Emilie Brûlé, Ulrich Boehm, Se-Jin Lee, Daniel J Bernard

Endocrinology. 2020 Jul; 161(7): bqaa056. Published online 2020 Apr 9. doi: 10.1210/endocr/bqaa056

PMCID:: PMC7286621

Abstract Article

Select item 682180711.

An enhancer cluster controls gene activity and topology of the SCN5A-SCN10A locus in vivo

Joyce C. K. Man, Rajiv A. Mohan, Malou van den Boogaard, Catharina R. E. Hilvering, Catherine Jenkins, Vincent Wakker, Valerio Bianchi, Wouter de Laat, Phil Barnett, Bastiaan J. Boukens, Vincent M. Christoffels

Nat Commun. 2019; 10: 4943. Published online 2019 Oct 30. doi: 10.1038/s41467-019-12856-5

PMCID:: PMC6821807

Abstract Article PDF–2.9M

Select item 668175212.

The TGFβ type I receptor TGFβRI functions as an inhibitor of BMP signaling in cartilage

Weiguang Wang, Hyelim Chun, Jongseung Baek, Joshua Elyahu Sadik, Anna Shirazyan, Peyman Razavi, Noah Lopez, Karen M. Lyons

Proc Natl Acad Sci U S A. 2019 Jul 30; 116(31): 15570–15579. Published online 2019 Jul 16. doi: 10.1073/pnas.1902927116

PMCID:: PMC6681752

Abstract Article PDF–2.4M

Select item 586818113.

CITGeneDB: a comprehensive database of human and mouse genes enhancing or suppressing cold-induced thermogenesis validated by perturbation experiments in mice

Jin Li, Su-Ping Deng, Gang Wei, Peng Yu

Database (Oxford) 2018; 2018: bay012. Published online 2018 Mar 23. doi: 10.1093/database/bay012

PMCID:: PMC5868181

Abstract Article PDF–653K

Select item 559565214.

Cerebral vein malformations result from loss of Twist1 expression and BMP signaling from skull progenitor cells and dura

Max A. Tischfield, Caroline D. Robson, Nicole M. Gilette, Shek Man Chim, Folasade A. Sofela, Michelle M. DeLisle, Alon Gelber, Brenda J. Barry, Sarah MacKinnon, Linda R. Dagi, Jeremy Nathans, Elizabeth C. Engle

Dev Cell. Author manuscript; available in PMC 2018 Sep 11.

Published in final edited form as: Dev Cell. 2017 Sep 11; 42(5): 445–461.e5. Published online 2017 Aug 30. doi: 10.1016/j.devcel.2017.07.027

PMCID:: PMC5595652

Abstract Article PDF–2.0M

Select item 556653315.

Activin receptor type 2A (ACVR2A) functions directly in osteoblasts as a negative regulator of bone mass

Brian C. Goh, Vandana Singhal, Angelica J. Herrera, Ryan E. Tomlinson, Soohyun Kim, Marie-Claude Faugere, Emily L. Germain-Lee, Thomas L. Clemens, Se-Jin Lee, Douglas J. DiGirolamo

J Biol Chem. 2017 Aug 18; 292(33): 13809–13822. Published online 2017 Jun 28. doi: 10.1074/jbc.M117.782128

PMCID:: PMC5566533

Abstract Article PDF–3.1M

Select item 546083016.

Follistatin Targets Distinct Pathways To Promote Brown Adipocyte Characteristics in Brown and White Adipose Tissues

Rajan Singh, Melissa Braga, Srinivasa T. Reddy, Se-Jin Lee, Meher Parveen, Victor Grijalva, Laurent Vergnes, Shehla Pervin

Endocrinology. 2017 May 1; 158(5): 1217–1230. Published online 2017 Jan 16. doi: 10.1210/en.2016-1607

PMCID:: PMC5460830

Abstract Article

Select item 537741017.

Activin A induces skeletal muscle catabolism via p38β mitogen‐activated protein kinase

Hui Ding, Guohua Zhang, Ka Wai Thomas Sin, Zhelong Liu, Ren‐Kuo Lin, Min Li, Yi‐Ping Li

J Cachexia Sarcopenia Muscle. 2017 Apr; 8(2): 202–212. Published online 2016 Sep 16. doi: 10.1002/jcsm.12145

PMCID:: PMC5377410

Abstract Article PDF–828K

Select item 529582118.

High-throughput discovery of novel developmental phenotypes

Mary E. Dickinson, Ann M. Flenniken, Xiao Ji, Lydia Teboul, Michael D. Wong, Jacqueline K. White, Terrence F. Meehan, Wolfgang J. Weninger, Henrik Westerberg, Hibret Adissu, Candice N. Baker, Lynette Bower, James M. Brown, L. Brianna Caddle, Francesco Chiani, Dave Clary, James Cleak, Mark J. Daly, James M. Denegre, Brendan Doe, Mary E. Dolan, Sarah M. Edie, Helmut Fuchs, Valerie Gailus-Durner, Antonella Galli, Alessia Gambadoro, Juan Gallegos, Shiying Guo, Neil R. Horner, Chih-wei Hsu, Sara J. Johnson, Sowmya Kalaga, Lance C. Keith, Louise Lanoue, Thomas N. Lawson, Monkol Lek, Manuel Mark, Susan Marschall, Jeremy Mason, Melissa L. McElwee, Susan Newbigging, Lauryl M.J. Nutter, Kevin A. Peterson, Ramiro Ramirez-Solis, Douglas J. Rowland, Edward Ryder, Kaitlin E. Samocha, John R. Seavitt, Mohammed Selloum, Zsombor Szoke-Kovacs, Masaru Tamura, Amanda G Trainor, Ilinca Tudose, Shigeharu Wakana, Jonathan Warren, Olivia Wendling, David B. West, Leeyean Wong, Atsushi Yoshiki, The International Mouse Phenotyping Consortium, Daniel G. MacArthur, Glauco P. Tocchini-Valentini, Xiang Gao, Paul Flicek, Allan Bradley, William C. Skarnes, Monica J. Justice, Helen E. Parkinson, Mark Moore, Sara Wells, Robert E. Braun, Karen L. Svenson, Martin Hrabe de Angelis, Yann Herault, Tim Mohun, Ann-Marie Mallon, R. Mark Henkelman, Steve D.M. Brown, David J. Adams, K.C. Kent Lloyd, Colin McKerlie, Arthur L. Beaudet, Maja Bucan, Stephen A. Murray

Nature. Author manuscript; available in PMC 2017 Mar 14.

Published in final edited form as: Nature. 2016 Sep 22; 537(7621): 508–514. Published online 2016 Sep 14. doi: 10.1038/nature19356

Correction in:: Nature. 2017 Nov 16; 551(7680): 398.

PMCID:: PMC5295821

Abstract Article PDF–3.0M

Select item 487865619.

The ability of inner cell mass cells to self-renew as embryonic stem cells is acquired upon epiblast specification

Thorsten Boroviak, Remco Loos, Paul Bertone, Austin Smith, Jennifer Nichols

Nat Cell Biol. Author manuscript; available in PMC 2016 May 24.

Published in final edited form as: Nat Cell Biol. 2014 Jun; 16(6): 516–528. Published online 2014 May 25. doi: 10.1038/ncb2965

PMCID:: PMC4878656

Abstract Article PDF–7.9M

Select item 481482220.

Mutant GDF5 enhances ameloblast differentiation via accelerated BMP2-induced Smad1/5/8 phosphorylation

Jia Liu, Kan Saito, Yuriko Maruya, Takashi Nakamura, Aya Yamada, Emiko Fukumoto, Momoko Ishikawa, Tsutomu Iwamoto, Kanako Miyazaki, Keigo Yoshizaki, Lihong Ge, Satoshi Fukumoto

Sci Rep. 2016; 6: 23670. Published online 2016 Mar 31. doi: 10.1038/srep23670

PMCID:: PMC4814822

Abstract Article PDF–1.8M

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