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Select item 99569291.

An Introduction and Overview of RON Receptor Tyrosine Kinase Signaling

Brian G. Hunt, Levi H. Fox, James C. Davis, Angelle Jones, Zhixin Lu, Susan E. Waltz

Genes (Basel) 2023 Feb; 14(2): 517. Published online 2023 Feb 17. doi: 10.3390/genes14020517

PMCID:: PMC9956929

Abstract Article PDF–668K

Select item 92923742.

A potential signaling axis between RON kinase receptor and hypoxia‐inducible factor‐1 alpha in pancreatic cancer

Akihisa Kato, Serina Ng, Amalraj Thangasamy, Haiyong Han, Wendi Zhou, Stephane Raeppel, Michael Fallon, Sushovan Guha, Sudhakar Ammanamanchi

Mol Carcinog. 2021 Nov; 60(11): 734–745. Published online 2021 Aug 4. doi: 10.1002/mc.23339

PMCID:: PMC9292374

Abstract Article PDF–2.3M

Select item 92626143.

A dual-activity topoisomerase complex regulates mRNA translation and turnover

Shuaikun Su, Yutong Xue, Alexei Sharov, Yongqing Zhang, Seung Kyu Lee, Jennifer L Martindale, Wen Li, Wai Lim Ku, Keji Zhao, Supriyo De, Weiping Shen, Payel Sen, Myriam Gorospe, Dongyi Xu, Weidong Wang

Nucleic Acids Res. 2022 Jul 8; 50(12): 7013–7033. Published online 2022 Jun 24. doi: 10.1093/nar/gkac538

PMCID:: PMC9262614

Abstract Article PDF–3.6M

Select item 92316234.

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1

Boris Simonetti, James L. Daly, Lorena Simón-Gracia, Katja Klein, Saroja Weeratunga, Carlos Antón-Plágaro, Allan Tobi, Lorna Hodgson, Philip A. Lewis, Kate J. Heesom, Deborah K. Shoemark, Andrew D. Davidson, Brett M. Collins, Tambet Teesalu, Yohei Yamauchi, Peter J. Cullen

Proc Natl Acad Sci U S A. 2022 Jun 21; 119(25): e2201980119. Published online 2022 Jun 13. doi: 10.1073/pnas.2201980119

PMCID:: PMC9231623

Abstract Article PDF–6.0M

Select item 91714115.

Physical and functional interactome atlas of human receptor tyrosine kinases

Kari Salokas, Xiaonan Liu, Tiina Öhman, Iftekhar Chowdhury, Lisa Gawriyski, Salla Keskitalo, Markku Varjosalo

EMBO Rep. 2022 Jun; 23(6): e54041. Published online 2022 Apr 5. doi: 10.15252/embr.202154041

PMCID:: PMC9171411

Abstract Article PDF–1.9M

Select item 86543656.

EGFR transactivates RON to drive oncogenic crosstalk

Carolina Franco Nitta, Ellen W Green, Elton D Jhamba, Justine M Keth, Iraís Ortiz-Caraveo, Rachel M Grattan, David J Schodt, Aubrey C Gibson, Ashwani Rajput, Keith A Lidke, Bridget S Wilson, Mara P Steinkamp, Diane S Lidke

eLife. 2021; 10: e63678. Published online 2021 Nov 25. doi: 10.7554/eLife.63678

PMCID:: PMC8654365

Abstract Article PDF–9.7M

Select item 81650307.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 79812568.

Tumor cell intrinsic RON signaling suppresses innate immune responses in breast cancer through inhibition of IRAK4 signaling.

Jennifer R. Bourn, Sasha J. Ruiz-Torres, Brian G. Hunt, Nancy M. Benight, Susan E. Waltz

Cancer Lett. Author manuscript; available in PMC 2022 Apr 10.

Published in final edited form as: Cancer Lett. 2021 Apr 10; 503: 75–90. Published online 2021 Jan 27. doi: 10.1016/j.canlet.2021.01.019

PMCID:: PMC7981256

Abstract Article PDF–1.3M

Select item 79181409.

Evidence for 2-Methoxyestradiol-Mediated Inhibition of Receptor Tyrosine Kinase RON in the Management of Prostate Cancer

Izhar Singh Batth, Shih-Bo Huang, Michelle Villarreal, Jingjing Gong, Divya Chakravarthy, Brian Keppler, Sridharan Jayamohan, Pawel Osmulski, Jianping Xie, Paul Rivas, Roble Bedolla, Michael A. Liss, I-Tien Yeh, Robert Reddick, Hiroshi Miyamoto, Rita Ghosh, Addanki P. Kumar

Int J Mol Sci. 2021 Feb; 22(4): 1852. Published online 2021 Feb 12. doi: 10.3390/ijms22041852

PMCID:: PMC7918140

Abstract Article PDF–13M

Select item 787591310.

Recepteur d'origine nantais contributes to the development of endometriosis via promoting epithelial‐mesenchymal transition of a endometrial epithelial cells

Qin Yu, Jianzhang Wang, Tiantian Li, Xinyue Guo, Shaojie Ding, Xuan Che, Libo Zhu, Yangying Peng, Xinxin Xu, Gen Zou, Xinmei Zhang

J Cell Mol Med. 2021 Feb; 25(3): 1601–1612. Published online 2021 Jan 6. doi: 10.1111/jcmm.16261

PMCID:: PMC7875913

Abstract Article PDF–3.6M

Select item 785102011.

Short-form RON (sf-RON) enhances glucose metabolism to promote cell proliferation via activating β-catenin/SIX1 signaling pathway in gastric cancer

Ziliang Wang, Yufei Yang, Shuang Hu, Jian He, Zheng Wu, Zihao Qi, Mingzhu Huang, Rujiao Liu, Ying Lin, Cong Tan, Midie Xu, Zhe Zhang

Cell Biol Toxicol. 2021; 37(1): 35–49. Published online 2020 May 12. doi: 10.1007/s10565-020-09525-5

PMCID:: PMC7851020

Abstract Article PDF–8.3M

Select item 778250112.

RON signalling promotes therapeutic resistance in ESR1 mutant breast cancer

Derek Dustin, Guowei Gu, Amanda R. Beyer, Sarah K. Herzog, David G. Edwards, Hangqing Lin, Thomas L. Gonzalez, Sandra L. Grimm, Cristian Coarfa, Doug W. Chan, Beom-Jun Kim, Jean-Paul De La O, Matthew J. Ellis, Dan Liu, Shunqiang Li, Alana L. Welm, Suzanne A. W. Fuqua

Br J Cancer. 2021 Jan 5; 124(1): 191–206. Published online 2020 Dec 1. doi: 10.1038/s41416-020-01174-z

PMCID:: PMC7782501

Abstract Article PDF–1.4M

Select item 765715413.

Receptor tyrosine kinases MET and RON as prognostic factors in diffuse large B‐cell lymphoma patients receiving R‐CHOP

Young Wha Koh, Hee Sang Hwang, Se Jin Jung, Chansik Park, Dok Hyun Yoon, Cheolwon Suh, Jooryung Huh

Cancer Sci. 2013 Sep; 104(9): 1245–1251. Published online 2013 Jul 11. doi: 10.1111/cas.12215

PMCID:: PMC7657154

Abstract Article PDF–1.2M

Select item 751032814.

MET and RON receptor tyrosine kinases in colorectal adenocarcinoma: molecular features as drug targets and antibody-drug conjugates for therapy

Hang-Ping Yao, Xiang-Min Tong, Rachel Hudson, Ming-Hai Wang

J Exp Clin Cancer Res. 2020; 39: 198. Published online 2020 Sep 22. doi: 10.1186/s13046-020-01711-x

PMCID:: PMC7510328

Abstract Article PDF–2.5M

Select item 739249115.

TGFβ attenuates cartilage extracellular matrix degradation via enhancing FBXO6-mediated MMP14 ubiquitination

Gangliang Wang, Shuai Chen, Ziang Xie, Shuying Shen, Wenbin Xu, Wenxiang Chen, Xiang Li, Yizheng Wu, Liangping Li, Bin Liu, Xianjun Ding, An Qin, Shunwu Fan

Ann Rheum Dis. 2020 Aug; 79(8): 1111–1120. Published online 2020 May 14. doi: 10.1136/annrheumdis-2019-216911

PMCID:: PMC7392491

Abstract Article PDF–14M

Select item 737385616.

RON and MET Co-overexpression Are Significant Pathological Characteristics of Poor Survival and Therapeutic Targets of Tyrosine Kinase Inhibitors in Triple-Negative Breast Cancer

Tian-Hao Weng, Min-Ya Yao, Xiang-Ming Xu, Chen-Yu Hu, Shu-Hao Yao, Yi-Zhi Liu, Zhi-Gang Wu, Tao-Ming Tang, Pei-Fen Fu, Ming-Hai Wang, Hang-Ping Yao

Cancer Res Treat. 2020 Jul; 52(3): 973–986. Published online 2020 Apr 22. doi: 10.4143/crt.2019.726

PMCID:: PMC7373856

Abstract Article PDF–5.0M

Select item 725585117.

MST1R (RON) expression is a novel prognostic biomarker for metastatic progression in breast cancer patients

Brian G Hunt, Christina A Wicker, Jennifer R Bourn, Elyse E Lower, Vinita Takiar, Susan E Waltz

Breast Cancer Res Treat. Author manuscript; available in PMC 2020 Jun 1.

Published in final edited form as: Breast Cancer Res Treat. 2020 Jun; 181(3): 529–540. Published online 2020 Apr 27. doi: 10.1007/s10549-020-05653-y

PMCID:: PMC7255851

Abstract Article PDF–2.1M

Select item 688918718.

OPN promotes the aggressiveness of non-small-cell lung cancer cells through the activation of the RON tyrosine kinase

Chengcheng Hao, Yuxin Cui, Siyuan Chang, Jing Huang, Emily Birkin, Mu Hu, Xiuyi Zhi, Wenbin Li, Lijian Zhang, Shan Cheng, Wen G. Jiang

Sci Rep. 2019; 9: 18101. Published online 2019 Dec 2. doi: 10.1038/s41598-019-54843-2

PMCID:: PMC6889187

Abstract Article PDF–3.6M

Select item 662586819.

MST1R Kinase Accelerates Pancreatic Cancer Progression Via Effects on both Epithelial Cells and Macrophages

Michele L. Babicky, Megan M. Harper, Jeffery Chakedis, Alex Cazes, Evangeline S. Mose, Dawn V. Jaquish, Randall P. French, Betzaira Childers, Hakan Alakus, Michael C. Schmid, Phillippe Foubert, Jaclyn Miyamoto, Patrick J. Holman, Zakkary J. Walterscheid, Chih-Min Tang, Nissi Varki, Jason K. Sicklick, Karen Messer, Judith A. Varner, Susan E. Waltz, Andrew M. Lowy

Oncogene. Author manuscript; available in PMC 2019 Oct 9.

Published in final edited form as: Oncogene. 2019 Jul; 38(28): 5599–5611. Published online 2019 Apr 9. doi: 10.1038/s41388-019-0811-9

PMCID:: PMC6625868

Abstract Article PDF–3.1M

Select item 653506220.

RON and RONΔ160 promote gastric cancer cell proliferation, migration, and adaption to hypoxia via interaction with β-catenin

Donghui Zhou, Ling Huang, Yong Zhou, Tao Wei, Lina Yang, Chao Li

Aging (Albany NY) 2019 May 15; 11(9): 2735–2748. Published online 2019 May 13. doi: 10.18632/aging.101945

PMCID:: PMC6535062

Abstract Article PDF–2.0M

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PMC Links for GEO Profiles (Select 109712786) (86)
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Nucleotide Links for Gene (Select 853007) (3)
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Homo sapiens chromosome 7 open reading frame 38, mRNA (cDNA clone IMAGE:3892368)
Homo sapiens chromosome 7 open reading frame 38, mRNA (cDNA clone IMAGE:3892368)
gi|16306932|gb|BC009536.1|

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