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Select item 112342051.

P2X7R Modulates NEK7-NLRP3 Interaction to Exacerbate Experimental Autoimmune Prostatitis via GSDMD-mediated Prostate Epithelial Cell Pyroptosis

Lei Chen, Yi Liu, Shaoyu Yue, Hui Wang, Jia Chen, Wenming Ma, Wenlong Xu, Muyang Xu, Ziqi Chen, Xianguo Chen, Li Zhang, Chaozhao Liang

Int J Biol Sci. 2024; 20(9): 3393–3411. Published online 2024 Jun 11. doi: 10.7150/ijbs.94704

PMCID:: PMC11234205

Abstract Article PDF–15M

Select item 111492692.

Gasdermin D deficiency aborts myeloid calcium influx to drive granulopoiesis in lupus nephritis

Jiani Shen, Feng Li, Xu Han, Dongying Fu, Yiping Xu, Changjian Zhu, Zhou Liang, Ziwen Tang, Ruilin Zheng, Xinrong Hu, Ruoni Lin, Qiaoqiao Pei, Jing Nie, Ning Luo, Xiaoyan Li, Wei Chen, Haiping Mao, Yi Zhou, Xueqing Yu

Cell Commun Signal. 2024; 22: 308. Published online 2024 Jun 3. doi: 10.1186/s12964-024-01681-z

PMCID:: PMC11149269

Abstract Article PDF–10M

Select item 110084183.

Silent information regulator sirtuin 1 ameliorates acute liver failure via the p53/glutathione peroxidase 4/gasdermin D axis

Xing-Nian Zhou, Quan Zhang, Hong Peng, Yu-Jie Qin, Yu-Hong Liu, Lu Wang, Ming-Liang Cheng, Xin-Hua Luo, Hong Li

World J Gastroenterol. 2024 Mar 21; 30(11): 1588–1608. Published online 2024 Mar 21. doi: 10.3748/wjg.v30.i11.1588

PMCID:: PMC11008418

Abstract Article PDF–18M

Select item 109080154.

TR4 worsen urosepsis by regulating GSDMD

Huan Wang, Shibin Zhu, Zhenwei Zhou, Zhenghui Wang, Wei Zhuang, Dingwei Xue, Zeyi Lu, Qiming Zheng, Lifeng Ding, Liangliang Ren, Wenqing Luo, Ruyue Wang, Guangju Ge, Liqun Xia, Gonghui Li, Haiyang Wu

Eur J Med Res. 2024; 29: 151. Published online 2024 Mar 1. doi: 10.1186/s40001-024-01742-6

PMCID:: PMC10908015

Abstract Article PDF–6.5M

Select item 108074055.

Structural insights into cytokine cleavage by inflammatory caspase-4

Pascal Devant, Ying Dong, Julian Mintseris, Weiyi Ma, Steven P. Gygi, Hao Wu, Jonathan C. Kagan

Nature. Author manuscript; available in PMC 2024 Jun 1.

Published in final edited form as: Nature. 2023 Dec; 624(7991): 451–459. Published online 2023 Nov 22. doi: 10.1038/s41586-023-06751-9

Correction in:: Nature. 2024 Jan 3

PMCID:: PMC10807405

Abstract Article PDF–6.9M

Select item 107981526.

GSDMD suppresses keratinocyte differentiation by inhibiting FLG expression and attenuating KCTD6-mediated HDAC1 degradation in atopic dermatitis

Yi Zhong, Taoyuan Huang, Xiaoli Li, Peiyi Luo, Bingjun Zhang

PeerJ. 2024; 12: e16768. Published online 2024 Jan 16. doi: 10.7717/peerj.16768

PMCID:: PMC10798152

Abstract Article PDF–19M

Select item 107764987.

O-GlcNAc modification of GSDMD attenuates LPS-induced endothelial cells pyroptosis

Fan Yu, Zhen Zhang, Yiping Leng, Alex F. Chen

Inflamm Res. 2024; 73(1): 5–17. Published online 2023 Nov 14. doi: 10.1007/s00011-023-01812-1

PMCID:: PMC10776498

Abstract Article PDF–1.7M

Select item 106368308.

System analysis based on the pyroptosis-related genes identifes GSDMD as a novel therapy target for skin cutaneous melanoma

Shixin Zhao, Yongkang Zhu, Hengdeng Liu, Xuefeng He, Julin Xie

J Transl Med. 2023; 21: 801. Published online 2023 Nov 10. doi: 10.1186/s12967-023-04513-9

PMCID:: PMC10636830

Abstract Article PDF–9.8M

Select item 105529939.

Expression and significance of effector proteins NLRP3 and gasdermin D N-terminal protein in the pyrolysis pathway in breast cancer

Ligao Wu, Xia Wu, Jinjie Liu, Yuanli Huang, Qing Zhu

Medicine (Baltimore) 2023 Oct 6; 102(40): e35440. Published online 2023 Oct 6. doi: 10.1097/MD.0000000000035440

PMCID:: PMC10552993

Abstract Article PDF–683K

Select item 1048820410.

Gasdermin D (GSDMD) Is Upregulated in Psoriatic Skin—A New Potential Link in the Pathogenesis of Psoriasis

Julia Nowowiejska, Anna Baran, Justyna Magdalena Hermanowicz, Anna Pryczynicz, Beata Sieklucka, Dariusz Pawlak, Iwona Flisiak

Int J Mol Sci. 2023 Sep; 24(17): 13047. Published online 2023 Aug 22. doi: 10.3390/ijms241713047

PMCID:: PMC10488204

Abstract Article PDF–4.0M

Select item 1029596911.

Gasdermin D Plays an Oncogenic Role in Glioma and Correlates to an Immunosuppressive Microenvironment

Mengyuan Li, Ping Jiang, Shuhua Wei, Yuhan Yang, Liting Xiong, Junjie Wang, Chunxiao Li

Biomolecules. 2023 Jun; 13(6): 904. Published online 2023 May 29. doi: 10.3390/biom13060904

PMCID:: PMC10295969

Abstract Article PDF–11M

Select item 1023742212.

TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing

Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan

Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233

PMCID:: PMC10237422

Abstract Article PDF–23M

Select item 1023297013.

Gasdermin D-mediated pyroptosis: mechanisms, diseases, and inhibitors

Zhen Dai, Wan-Cong Liu, Xiao-Yi Chen, Xiao Wang, Jun-Long Li, Xiang Zhang

Front Immunol. 2023; 14: 1178662. Published online 2023 May 18. doi: 10.3389/fimmu.2023.1178662

PMCID:: PMC10232970

Abstract Article PDF–2.3M

Select item 1022862514.

Copy number variation of gasdermin D gene is associated with atrial fibrillation-related thromboembolic stroke

Pang-Shuo Huang, Jen-Fang Cheng, Guan-Wei Li, Eric Y Chuang, Jien-Jiun Chen, Fu-Chun Chiu, Cho-Kai Wu, Yi-Chih Wang, Juey-Jen Hwang, Chia-Ti Tsai

Europace. 2023 May; 25(5): euad103. Published online 2023 Apr 21. doi: 10.1093/europace/euad103

PMCID:: PMC10228625

Abstract Article PDF–355K

Select item 998059015.

The Role of Gasdermin-D-Mediated Pryoptosis in Organ Injury and Its Therapeutic Implications

Joud Mulla, Rohan Katti, Melanie J. Scott

Organogenesis. 2023; 19(1): 2177484. Published online 2023 Feb 22. doi: 10.1080/15476278.2023.2177484

PMCID:: PMC9980590

Abstract Article PDF–859K

Select item 995804216.

Gasdermin-D activation promotes NLRP3 activation and host resistance to Leishmania infection

Keyla S. G. de Sá, Luana A. Amaral, Tamara S. Rodrigues, Adriene Y. Ishimoto, Warrison A. C. de Andrade, Leticia de Almeida, Felipe Freitas-Castro, Sabrina S. Batah, Sergio C. Oliveira, Mônica T. Pastorello, Alexandre T. Fabro, Dario S. Zamboni

Nat Commun. 2023; 14: 1049. Published online 2023 Feb 24. doi: 10.1038/s41467-023-36626-6

PMCID:: PMC9958042

Abstract Article PDF–4.7M

Select item 993563017.

Oxidized mitochondrial DNA induces gasdermin D oligomerization in systemic lupus erythematosus

Naijun Miao, Zhuning Wang, Qinlan Wang, Hongyan Xie, Ninghao Yang, Yanzhe Wang, Jin Wang, Haixia Kang, Wenjuan Bai, Yuanyuan Wang, Rui He, Kepeng Yan, Yang Wang, Qiongyi Hu, Zhaoyuan Liu, Fubin Li, Feng Wang, Florent Ginhoux, Xiaoling Zhang, Jianyong Yin, Limin Lu, Jing Wang

Nat Commun. 2023; 14: 872. Published online 2023 Feb 16. doi: 10.1038/s41467-023-36522-z

PMCID:: PMC9935630

Abstract Article PDF–5.8M

Select item 986113118.

The Mechanism of Osteoprotegerin-Induced Osteoclast Pyroptosis In Vitro

Jiaqiao Zhu, Yonggang Ma, Jie Wang, Yangyang Wang, Waseem Ali, Hui Zou, Hongyan Zhao, Xishuai Tong, Ruilong Song, Zongping Liu

Int J Mol Sci. 2023 Jan; 24(2): 1518. Published online 2023 Jan 12. doi: 10.3390/ijms24021518

PMCID:: PMC9861131

Abstract Article PDF–3.1M

Select item 976905119.

Elevated circulating levels of gasdermin D are related to acute myocardial infarction and pyrogptosis

Yawen Weng, Bozhi Ye, Jiahui Lin, Shuang Lin, Lingfeng Zhong, Weijian Huang, Xueli Cai, Weiqi Wang

BMC Cardiovasc Disord. 2022; 22: 554. Published online 2022 Dec 21. doi: 10.1186/s12872-022-02998-8

PMCID:: PMC9769051

Abstract Article PDF–898K

Select item 956492320.

New Insights Relating Gasdermin B to the Onset of Childhood Asthma

Nathan Schoettler, Eishika Dissanayake, Mark W. Craven, Jeremiah S. Yee, Joshua Eliason, Eric M. Schauberger, Robert F. Lemanske, Jr., Carole Ober, James E. Gern

Am J Respir Cell Mol Biol. 2022 Oct 1; 67(4): 430–437. Published online 2022 May 17. doi: 10.1165/rcmb.2022-0043PS

PMCID:: PMC9564923

Abstract Article PDF–838K

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Hematopoietic cell response to Xist deficiency in females: time course
Hematopoietic cell response to Xist deficiency in females: time course
Accession: GDS4755

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Estrogen effect on male and female haematopoietic stem cells
Estrogen effect on male and female haematopoietic stem cells
Accession: GDS4944

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