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Select item 93485761.

Chr21 protein–protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer’s disease

Julia Viard, Yann Loe-Mie, Rachel Daudin, Malik Khelfaoui, Christine Plancon, Anne Boland, Francisco Tejedor, Richard L Huganir, Eunjoon Kim, Makoto Kinoshita, Guofa Liu, Volker Haucke, Thomas Moncion, Eugene Yu, Valérie Hindie, Henri Bléhaut, Clotilde Mircher, Yann Herault, Jean-François Deleuze, Jean-Christophe Rain, Michel Simonneau, Aude-Marie Lepagnol-Bestel

Life Sci Alliance. 2022 Dec; 5(12): e202101205. Published online 2022 Aug 1. doi: 10.26508/lsa.202101205

PMCID:: PMC9348576

Abstract Article PDF–3.0M

Select item 81650302.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 76869773.

PLA2G16 is a mutant p53/KLF5 transcriptional target and promotes glycolysis of pancreatic cancer

Wei Xia, Hansong Bai, Ying Deng, Yi Yang

J Cell Mol Med. 2020 Nov; 24(21): 12642–12655. Published online 2020 Sep 27. doi: 10.1111/jcmm.15832

PMCID:: PMC7686977

Abstract Article PDF–2.4M

Select item 71699834.

A reference map of the human binary protein interactome

Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood

Nature. Author manuscript; available in PMC 2020 Oct 8.

Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x

PMCID:: PMC7169983

Abstract Article PDF–5.4M

Select item 65908205.

Screening of urine identifies PLA2G16 as a field defect methylation biomarker for prostate cancer detection

William E. Jarrard, Adam Schultz, Tyler Etheridge, Shivashankar Damodaran, Glenn O. Allen, David Jarrard, Bing Yang

PLoS One. 2019; 14(6): e0218950. Published online 2019 Jun 24. doi: 10.1371/journal.pone.0218950

PMCID:: PMC6590820

Abstract Article PDF–909K

Select item 49512686.

PLA2G16 promotes osteosarcoma metastasis and drug resistance via the MAPK pathway

Lin Li, Shoulei Liang, Amanda R. Wasylishen, Yanqin Zhang, Xueli Yang, Bingzheng Zhou, Luling Shan, Xiuxin Han, Tianyang Mu, Guowen Wang, Shunbin Xiong

Oncotarget. 2016 Apr 5; 7(14): 18021–18035. Published online 2016 Feb 25. doi: 10.18632/oncotarget.7694

PMCID:: PMC4951268

Abstract Article PDF–12M

Select item 45750937.

H-rev107 Regulates Cytochrome P450 Reductase Activity and Increases Lipid Accumulation

Fu-Ming Tsai, Mao-Liang Chen, Lu-Kai Wang, Ming-Cheng Lee

PLoS One. 2015; 10(9): e0138586. Published online 2015 Sep 18. doi: 10.1371/journal.pone.0138586

PMCID:: PMC4575093

Abstract Article PDF–4.2M

Select item 44980868.

Interaction of Phospholipase A/Acyltransferase-3 with Pex19p: A POSSIBLE INVOLVEMENT IN THE DOWN-REGULATION OF PEROXISOMES

Toru Uyama, Katsuhisa Kawai, Nozomu Kono, Masahiro Watanabe, Kazuhito Tsuboi, Tomohito Inoue, Nobukazu Araki, Hiroyuki Arai, Natsuo Ueda

J Biol Chem. 2015 Jul 10; 290(28): 17520–17534. Published online 2015 May 27. doi: 10.1074/jbc.M114.635433

PMCID:: PMC4498086

Abstract Article PDF–1.4M

Select item 44362979.

PLA2G16 Expression in Human Osteosarcoma Is Associated with Pulmonary Metastasis and Poor Prognosis

Shoulei Liang, Zhiwu Ren, Xiuxin Han, Jilong Yang, Luling Shan, Lin Li, Binying Wang, Qianyi Zhang, Tianyang Mu, Kexin Chen, Shunbin Xiong, Guowen Wang

PLoS One. 2015; 10(5): e0127236. Published online 2015 May 18. doi: 10.1371/journal.pone.0127236

PMCID:: PMC4436297

Abstract Article PDF–1.4M

Select item 427090810.

LRAT-specific domain facilitates Vitamin A metabolism by domain swapping in HRASLS

Marcin Golczak, Avery E. Sears, Philip D. Kiser, Krzysztof Palczewski

Nat Chem Biol. Author manuscript; available in PMC 2015 Jul 1.

Published in final edited form as: Nat Chem Biol. 2015 Jan; 11(1): 26–32. Published online 2014 Nov 10. doi: 10.1038/nchembio.1687

PMCID:: PMC4270908

Abstract Article PDF–2.3M

Select item 426658811.

A proteome-scale map of the human interactome network

Thomas Rolland, Murat Taşan, Benoit Charloteaux, Samuel J. Pevzner, Quan Zhong, Nidhi Sahni, Song Yi, Irma Lemmens, Celia Fontanillo, Roberto Mosca, Atanas Kamburov, Susan D. Ghiassian, Xinping Yang, Lila Ghamsari, Dawit Balcha, Bridget E. Begg, Pascal Braun, Marc Brehme, Martin P. Broly, Anne-Ruxandra Carvunis, Dan Convery-Zupan, Roser Corominas, Jasmin Coulombe-Huntington, Elizabeth Dann, Matija Dreze, Amélie Dricot, Changyu Fan, Eric Franzosa, Fana Gebreab, Bryan J. Gutierrez, Madeleine F. Hardy, Mike Jin, Shuli Kang, Ruth Kiros, Guan Ning Lin, Katja Luck, Andrew MacWilliams, Jörg Menche, Ryan R. Murray, Alexandre Palagi, Matthew M. Poulin, Xavier Rambout, John Rasla, Patrick Reichert, Viviana Romero, Elien Ruyssinck, Julie M. Sahalie, Annemarie Scholz, Akash A. Shah, Amitabh Sharma, Yun Shen, Kerstin Spirohn, Stanley Tam, Alexander O. Tejeda, Shelly A. Wanamaker, Jean-Claude Twizere, Kerwin Vega, Jennifer Walsh, Michael E. Cusick, Yu Xia, Albert-László Barabási, Lilia M. Iakoucheva, Patrick Aloy, Javier De Las Rivas, Jan Tavernier, Michael A. Calderwood, David E. Hill, Tong Hao, Frederick P. Roth, Marc Vidal

Cell. Author manuscript; available in PMC 2015 Nov 20.

Published in final edited form as: Cell. 2014 Nov 20; 159(5): 1212–1226. doi: 10.1016/j.cell.2014.10.050

PMCID:: PMC4266588

Abstract Article PDF–3.1M

Select item 412182912.

Pla2g16 phospholipase mediates gain-of-function activities of mutant p53

Shunbin Xiong, Huolin Tu, Madhusudhan Kollareddy, Vinod Pant, Qin Li, Yun Zhang, James G. Jackson, Young-Ah Suh, Ana C. Elizondo-Fraire, Peirong Yang, Gilda Chau, Mehrnoosh Tashakori, Amanda R. Wasylishen, Zhenlin Ju, Hilla Solomon, Varda Rotter, Bin Liu, Adel K. El-Naggar, Lawrence A. Donehower, Luis Alfonso Martinez, Guillermina Lozano

Proc Natl Acad Sci U S A. 2014 Jul 29; 111(30): 11145–11150. Published online 2014 Jul 14. doi: 10.1073/pnas.1404139111

PMCID:: PMC4121829

Abstract Article PDF–1.2M

Select item 401274313.

Phospholipase A/Acyltransferase enzyme activity of H-rev107 inhibits the H-RAS signaling pathway

Chun-Hua Wang, Rong-Yaun Shyu, Chang-Chieh Wu, Tzung-Chieh Tsai, Lu-Kai Wang, Mao-Liang Chen, Shun-Yuan Jiang, Fu-Ming Tsai

J Biomed Sci. 2014; 21(1): 36. Published online 2014 May 1. doi: 10.1186/1423-0127-21-36

PMCID:: PMC4012743

Abstract Article PDF–1.1M

Select item 347168414.

Structure/Function Relationships of Adipose Phospholipase A₂ Containing a Cys-His-His Catalytic Triad

Xiao-Yan Pang, Jian Cao, Linsee Addington, Scott Lovell, Kevin P. Battaile, Na Zhang, J. L. Uma Maheswar Rao, Edward A. Dennis, Alexander R. Moise

J Biol Chem. 2012 Oct 12; 287(42): 35260–35274. Published online 2012 Aug 25. doi: 10.1074/jbc.M112.398859

PMCID:: PMC3471684

Abstract Article PDF–2.3M

Select item 344252315.

Generation of N-Acylphosphatidylethanolamine by Members of the Phospholipase A/Acyltransferase (PLA/AT) Family

Toru Uyama, Natsuki Ikematsu, Manami Inoue, Naoki Shinohara, Xing-Hua Jin, Kazuhito Tsuboi, Takeharu Tonai, Akira Tokumura, Natsuo Ueda

J Biol Chem. 2012 Sep 14; 287(38): 31905–31919. Published online 2012 Jul 23. doi: 10.1074/jbc.M112.368712

PMCID:: PMC3442523

Abstract Article PDF–2.2M

Select item 339065316.

Structural Basis for the Acyltransferase Activity of Lecithin:Retinol Acyltransferase-like Proteins

Marcin Golczak, Philip D. Kiser, Avery E. Sears, David T. Lodowski, William S. Blaner, Krzysztof Palczewski

J Biol Chem. 2012 Jul 6; 287(28): 23790–23807. Published online 2012 May 17. doi: 10.1074/jbc.M112.361550

PMCID:: PMC3390653

Abstract Article PDF–4.5M

Select item 317805917.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 286311618.

AdPLA ablation increases lipolysis and prevents obesity induced by high fat feeding or leptin deficiency

Kathy Jaworski, Maryam Ahmadian, Robin E. Duncan, Eszter Sarkadi-Nagy, Krista A. Varady, Marc K. Hellerstein, Hui-Young Lee, Varman T. Samuel, Gerald I. Shulman, Kee-Hong Kim, Sarah de Val, Chulho Kang, Hei Sook Sul

Nat Med. Author manuscript; available in PMC 2010 May 4.

Published in final edited form as: Nat Med. 2009 Feb; 15(2): 159–168. Published online 2009 Jan 11. doi: 10.1038/nm.1904

PMCID:: PMC2863116

Abstract Article PDF–2.2M

Select item 265666219.

The tumor suppressor gene H-Rev107 functions as a novel Ca²⁺-independent cytosolic phospholipase A_1/2 of the thiol hydrolase type

Toru Uyama, Jun Morishita, Xing-Hua Jin, Yasuo Okamoto, Kazuhito Tsuboi, Natsuo Ueda

J Lipid Res. 2009 Apr; 50(4): 685–693. doi: 10.1194/jlr.M800453-JLR200

PMCID:: PMC2656662

Abstract Article PDF–1.2M

Select item 253309120.

Identification and Functional Characterization of Adipose-specific Phospholipase A₂ (AdPLA)

Robin E. Duncan, Eszter Sarkadi-Nagy, Kathy Jaworski, Maryam Ahmadian, Hei Sook Sul

J Biol Chem. 2008 Sep 12; 283(37): 25428–25436. doi: 10.1074/jbc.M804146200

PMCID:: PMC2533091

Abstract Article PDF–506K

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