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Select item 112362951.

BRG1 promotes liver cancer cell proliferation and metastasis by enhancing mitochondrial function and ATP5A1 synthesis through TOMM40

Yongfeng Hui, Junzhi Leng, Dong Jin, Genwang Wang, Kejun Liu, Yang Bu, Qi Wang

Cancer Biol Ther. 2024; 25(1): 2375440. Published online 2024 Jul 8. doi: 10.1080/15384047.2024.2375440

PMCID:: PMC11236295

Abstract Article PDF–15M

Select item 111792262.

Gastric SMARCA4-deficient undifferentiated tumor (SMARCA4-UT): a clinicopathological analysis of four rare cases

Ping Zhou, Yiyun Fu, Weiya Wang, Yuan Tang, Lili Jiang

Orphanet J Rare Dis. 2024; 19: 237. Published online 2024 Jun 14. doi: 10.1186/s13023-024-03244-4

PMCID:: PMC11179226

Abstract Article PDF–3.3M

Select item 110616083.

Molecular and Pathologic Characterization of YAP1-Expressing Small Cell Lung Cancer Cell Lines Leads to Reclassification as SMARCA4-Deficient Malignancies

Jin Ng, Ling Cai, Luc Girard, Owen W.J. Prall, Neeha Rajan, Christine Khoo, Ahida Batrouney, David J. Byrne, Danielle K. Boyd, Ariena J. Kersbergen, Michael Christie, John D. Minna, Marian L. Burr, Kate D. Sutherland

Clin Cancer Res. 2024 May 1; 30(9): 1846–1858. Published online 2023 Dec 7. doi: 10.1158/1078-0432.CCR-23-2360

PMCID:: PMC11061608

Abstract Article PDF–35M

Select item 110598954.

ARID1 and BRG1 Expression in Endometrial Cancer

EMMANUEL N. KONTOMANOLIS, PANAGIOTIS SYMEONIDIS, KONSTANTINOS NIKOLETTOS, PARASKEVAS PERROS, ACHIM RODY, PANAGIOTIS TSIKOURAS, NIKOLAOS NIKOLETTOS, ALEXANDRA GIATROMANOLAKI

In Vivo. 2024 May-Jun; 38(3): 1260–1265. Published online 2024 May 3. doi: 10.21873/invivo.13563

PMCID:: PMC11059895

Abstract Article PDF–1.8M

Select item 109332675.

Interaction network of human early embryonic transcription factors

Lisa Gawriyski, Zenglai Tan, Xiaonan Liu, Iftekhar Chowdhury, Dicle Malaymar Pinar, Qin Zhang, Jere Weltner, Eeva-Mari Jouhilahti, Gong-Hong Wei, Juha Kere, Markku Varjosalo

EMBO Rep. 2024 Mar; 25(3): 1589–1622. Published online 2024 Jan 31. doi: 10.1038/s44319-024-00074-0

PMCID:: PMC10933267

Abstract Article PDF–2.9M

Select item 109069286.

BRG1 establishes the neuroectodermal chromatin landscape to restrict dorsal cell fates

Jackson A. Hoffman, Ginger W. Muse, Lee F. Langer, A. Isabella Patterson, Isabella Gandara, James M. Ward, Trevor K. Archer

Sci Adv. 2024 Mar 1; 10(9): eadj5107. Published online 2024 Mar 1. doi: 10.1126/sciadv.adj5107

PMCID:: PMC10906928

Abstract Article PDF–6.1M

Select item 107649587.

TRIM28-mediated nucleocapsid protein SUMOylation enhances SARS-CoV-2 virulence

Jiang Ren, Shuai Wang, Zhi Zong, Ting Pan, Sijia Liu, Wei Mao, Huizhe Huang, Xiaohua Yan, Bing Yang, Xin He, Fangfang Zhou, Long Zhang

Nat Commun. 2024; 15: 244. Published online 2024 Jan 4. doi: 10.1038/s41467-023-44502-6

PMCID:: PMC10764958

Abstract Article PDF–4.4M

Select item 107193308.

The chromatin remodeling protein BRG1 regulates HSC-myofibroblast differentiation and liver fibrosis

Yuwen Zhu, Aoqi Kang, Yameng Kuai, Yan Guo, Xiulian Miao, Li Zhu, Ming Kong, Nan Li

Cell Death Dis. 2023 Dec; 14(12): 826. Published online 2023 Dec 14. doi: 10.1038/s41419-023-06351-5

PMCID:: PMC10719330

Abstract Article PDF–7.2M

Select item 105658769.

Pulse-SILAC and Interactomics Reveal Distinct DDB1-CUL4–Associated Factors, Cellular Functions, and Protein Substrates

Jennifer Raisch, Marie-Line Dubois, Marika Groleau, Dominique Lévesque, Thomas Burger, Carla-Marie Jurkovic, Romain Brailly, Gwendoline Marbach, Alyson McKenna, Catherine Barrette, Pierre-Étienne Jacques, François-Michel Boisvert

Mol Cell Proteomics. 2023 Oct; 22(10): 100644. Published online 2023 Sep 7. doi: 10.1016/j.mcpro.2023.100644

PMCID:: PMC10565876

Abstract Article PDF–3.7M

Select item 1048053510.

Mapping the MOB proteins’ proximity network reveals a unique interaction between human MOB3C and the RNase P complex

Islam E. Elkholi, Jonathan Boulais, Marie-Pier Thibault, Hong-Duc Phan, Amélie Robert, Lien B. Lai, Denis Faubert, Matthew J. Smith, Venkat Gopalan, Jean-Franҫois Côté

J Biol Chem. 2023 Sep; 299(9): 105123. Published online 2023 Aug 1. doi: 10.1016/j.jbc.2023.105123

PMCID:: PMC10480535

Abstract Article PDF–2.4M

Select item 1046299011.

SMARCA4 as a support for the differential diagnosis of poorly differentiated lung carcinomas

Martina Panozzi, Greta Alì, Agnese Proietti, Franca Melfi, Carmelina C. Zirafa, Marco Lucchi, Gabriella Fontanini

Pathologica. 2023 Jun; 115(3): 164–171. Published online 2023 Jun 30. doi: 10.32074/1591-951X-847

PMCID:: PMC10462990

Abstract Article PDF–313K

Select item 1041715812.

Pathogenic germline variants in SMARCA4 and further cancer predisposition genes in early onset ovarian cancer

Natalie Herold, Johanna Schmolling, Corinna Ernst, Beyhan Ataseven, Britta Blümcke, Birgid Schömig‐Markiefka, Sebastian Heikaus, Uwe‐Jochen Göhring, Christoph Engel, Björn Lampe, Kerstin Rhiem, Philipp Harter, Jan Hauke, Rita K. Schmutzler, Eric Hahnen

Cancer Med. 2023 Jul; 12(14): 15256–15260. Published online 2023 Jun 22. doi: 10.1002/cam4.6214

PMCID:: PMC10417158

Abstract Article PDF–199K

Select item 1037444113.

The role of chromatin remodeler SMARCA4/BRG1 in brain cancers: a potential therapeutic target

Sophie M. Navickas, Katherine A. Giles, Kate H. Brettingham-Moore, Phillippa C. Taberlay

Oncogene. 2023; 42(31): 2363–2373. Published online 2023 Jul 11. doi: 10.1038/s41388-023-02773-9

PMCID:: PMC10374441

Abstract Article PDF–1.2M

Select item 1024379514.

Redistribution of the chromatin remodeler Brg1 directs smooth muscle–derived adventitial progenitor–to–myofibroblast differentiation and vascular fibrosis

Austin J. Jolly, Sizhao Lu, Allison M. Dubner, Keith A. Strand, Marie F. Mutryn, Aaron Pilotti-Riley, Etienne P. Danis, Raphael A. Nemenoff, Karen S. Moulton, Mark W. Majesky, Mary C.M. Weiser-Evans

JCI Insight. 2023 May 8; 8(9): e164862. Published online 2023 May 8. doi: 10.1172/jci.insight.164862

PMCID:: PMC10243795

Abstract Article PDF–2.7M

Select item 1024311615.

Comprehensive Interactome Mapping of the DNA Repair Scaffold SLX4 Using Proximity Labeling and Affinity Purification

Camila M. Aprosoff, Boris J.A. Dyakov, Vivian H.W. Cheung, Cassandra J. Wong, Mikaela Palandra, Anne-Claude Gingras, Haley D.M. Wyatt

J Proteome Res. 2023 Jun 2; 22(6): 1660–1681. Published online 2023 Apr 18. doi: 10.1021/acs.jproteome.2c00706

PMCID:: PMC10243116

Abstract Article PDF–13M

Select item 1023742216.

TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing

Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan

Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233

PMCID:: PMC10237422

Abstract Article PDF–23M

Select item 1016456417.

The ubiquitin-specific protease USP36 SUMOylates EXOSC10 and promotes the nucleolar RNA exosome function in rRNA processing

Yingxiao Chen, Yanping Li, Roselyn S Dai, Jonathan C Savage, Ujwal Shinde, John Klimek, Larry L David, Emma A Young, Markus Hafner, Rosalie C Sears, Xiao-Xin Sun, Mu-Shui Dai

Nucleic Acids Res. 2023 May 8; 51(8): 3934–3949. Published online 2023 Mar 13. doi: 10.1093/nar/gkad140

PMCID:: PMC10164564

Abstract Article PDF–3.8M

Select item 1015161518.

Cross-linking mass spectrometry discovers, evaluates, and corroborates structures and protein–protein interactions in the human cell

Tara K. Bartolec, Xabier Vázquez-Campos, Alexander Norman, Clement Luong, Marcus Johnson, Richard J. Payne, Marc R. Wilkins, Joel P. Mackay, Jason K. K. Low

Proc Natl Acad Sci U S A. 2023 Apr 25; 120(17): e2219418120. Published online 2023 Apr 18. doi: 10.1073/pnas.2219418120

PMCID:: PMC10151615

Abstract Article PDF–2.9M

Select item 1002542519.

Protein interaction studies in human induced neurons indicate convergent biology underlying autism spectrum disorders

Greta Pintacuda, Yu-Han H. Hsu, Kalliopi Tsafou, Ka Wan Li, Jacqueline M. Martín, Jackson Riseman, Julia C. Biagini, Joshua K.T. Ching, Daya Mena, Miguel A. Gonzalez-Lozano, Shawn B. Egri, Jake Jaffe, August B. Smit, Nadine Fornelos, Kevin C. Eggan, Kasper Lage

Cell Genom. 2023 Mar 8; 3(3): 100250. Published online 2023 Jan 24. doi: 10.1016/j.xgen.2022.100250

PMCID:: PMC10025425

Abstract Article PDF–22M

Select item 1001113920.

Pharmacological disruption of mSWI/SNF complex activity restricts SARS-CoV-2 infection

Jin Wei, Ajinkya Patil, Clayton K. Collings, Mia Madel Alfajaro, Yu Liang, Wesley L. Cai, Madison S. Strine, Renata B. Filler, Peter C. DeWeirdt, Ruth E. Hanna, Bridget L. Menasche, Arya Ökten, Mario A. Peña-Hernández, Jon Klein, Andrew McNamara, Romel Rosales, Briana L. McGovern, M. Luis Rodriguez, Adolfo García-Sastre, Kris M. White, Yiren Qin, John G. Doench, Qin Yan, Akiko Iwasaki, Thomas P. Zwaka, Jun Qi, Cigall Kadoch, Craig B. Wilen

Nat Genet. 2023; 55(3): 471–483. Published online 2023 Mar 9. doi: 10.1038/s41588-023-01307-z

PMCID:: PMC10011139

Abstract Article PDF–21M

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PMC Links for GEO Profiles (Select 110635520) (444)
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Ovarian normal surface epithelia and ovarian cancer epithelial cells
Ovarian normal surface epithelia and ovarian cancer epithelial cells
Accession: GDS3592

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Pulmonary fibrosis with associated pulmonary hypertension: lung explants
Pulmonary fibrosis with associated pulmonary hypertension: lung explants
Accession: GDS4549

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