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Select item 111391071.

Multiple roles of the DSCR1 (Adapt78 or RCAN1) gene and its protein product Calcipressin 1 (or RCAN1) in disease

C. D. Harris, G. Ermak, K. J. A. Davies

Cell Mol Life Sci. 2005 Nov; 62(21): 2477–2486. Published online 2005 Oct 18. doi: 10.1007/s00018-005-5085-4

PMCID:: PMC11139107

Abstract Article PDF–132K

Select item 101516152.

Cross-linking mass spectrometry discovers, evaluates, and corroborates structures and protein–protein interactions in the human cell

Tara K. Bartolec, Xabier Vázquez-Campos, Alexander Norman, Clement Luong, Marcus Johnson, Richard J. Payne, Marc R. Wilkins, Joel P. Mackay, Jason K. K. Low

Proc Natl Acad Sci U S A. 2023 Apr 25; 120(17): e2219418120. Published online 2023 Apr 18. doi: 10.1073/pnas.2219418120

PMCID:: PMC10151615

Abstract Article PDF–2.9M

Select item 100729063.

Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity

Martin Golkowski, Andrea Lius, Tanmay Sapre, Ho-Tak Lau, Taylor Moreno, Dustin J. Maly, Shao-En Ong

Mol Cell. Author manuscript; available in PMC 2023 Apr 4.

Published in final edited form as: Mol Cell. 2023 Mar 2; 83(5): 803–818.e8. Published online 2023 Feb 2. doi: 10.1016/j.molcel.2023.01.015

PMCID:: PMC10072906

Abstract Article PDF–4.2M

Select item 96888814.

Overexpression of RCAN1, a Gene on Human Chromosome 21, Alters Cell Redox and Mitochondrial Function in Enamel Cells

Yi Li, Veronica Costiniti, Guilherme H. Souza Bomfim, Maria Neginskaya, Ga-Yeon Son, Beverly Rothermel, Evgeny Pavlov, Rodrigo S. Lacruz

Cells. 2022 Nov; 11(22): 3576. Published online 2022 Nov 11. doi: 10.3390/cells11223576

PMCID:: PMC9688881

Abstract Article PDF–1.5M

Select item 95329005.

Targeting upregulated RNA binding protein RCAN1.1: a promising strategy for neuroprotection in acute ischemic stroke

Yan Yun, Xiaxin Yang, Shichuan Tan, Pin Wang, Yanbin Ji, Xiulian Sun

CNS Neurosci Ther. 2022 Nov; 28(11): 1814–1828. Published online 2022 Jul 28. doi: 10.1111/cns.13921

PMCID:: PMC9532900

Abstract Article PDF–21M

Select item 94525776.

Regulator of calcineurin 1 deletion attenuates mitochondrial dysfunction and apoptosis in acute kidney injury through JNK/Mff signaling pathway

Jing-Jie Xiao, Qing Liu, Ying Li, Fang-Fang Peng, Shan Wang, Zhihan Zhang, Hui Liu, Hong Yu, Shengxiang Tao, Bai-Fang Zhang

Cell Death Dis. 2022 Sep; 13(9): 774. Published online 2022 Sep 7. doi: 10.1038/s41419-022-05220-x

PMCID:: PMC9452577

Abstract Article PDF–8.3M

Select item 93485767.

Chr21 protein–protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer’s disease

Julia Viard, Yann Loe-Mie, Rachel Daudin, Malik Khelfaoui, Christine Plancon, Anne Boland, Francisco Tejedor, Richard L Huganir, Eunjoon Kim, Makoto Kinoshita, Guofa Liu, Volker Haucke, Thomas Moncion, Eugene Yu, Valérie Hindie, Henri Bléhaut, Clotilde Mircher, Yann Herault, Jean-François Deleuze, Jean-Christophe Rain, Michel Simonneau, Aude-Marie Lepagnol-Bestel

Life Sci Alliance. 2022 Dec; 5(12): e202101205. Published online 2022 Aug 1. doi: 10.26508/lsa.202101205

PMCID:: PMC9348576

Abstract Article PDF–3.0M

Select item 92959098.

Down Syndrome Candidate Region 1 Isoform 1L regulated tumor growth by targeting both angiogenesis and tumor cells

Chen Chen, Pengfei Cui, Kevin Zhao, Gengming Niu, Shiqiang Hou, Dezheng Zhao, Huiyan Zeng

Microvasc Res. Author manuscript; available in PMC 2023 Mar 1.

Published in final edited form as: Microvasc Res. 2022 Mar; 140: 104305. Published online 2021 Dec 24. doi: 10.1016/j.mvr.2021.104305

PMCID:: PMC9295909

Abstract Article PDF–1.6M

Select item 92063139.

RCAN1-mediated calcineurin inhibition as a target for cancer therapy

Mengyi Lao, Xiaozhen Zhang, Hanshen Yang, Xueli Bai, Tingbo Liang

Mol Med. 2022; 28: 69. Published online 2022 Jun 18. doi: 10.1186/s10020-022-00492-7

PMCID:: PMC9206313

Abstract Article PDF–3.1M

Select item 911973610.

OpenCell: proteome-scale endogenous tagging enables the cartography of human cellular organization

Nathan H. Cho, Keith C. Cheveralls, Andreas-David Brunner, Kibeom Kim, André C. Michaelis, Preethi Raghavan, Hirofumi Kobayashi, Laura Savy, Jason Y. Li, Hera Canaj, James Y.S. Kim, Edna M. Stewart, Christian Gnann, Frank McCarthy, Joana P. Cabrera, Rachel M. Brunetti, Bryant B. Chhun, Greg Dingle, Marco Y. Hein, Bo Huang, Shalin B. Mehta, Jonathan S. Weissman, Rafael Gómez-Sjöberg, Daniel N. Itzhak, Loic A. Royer, Matthias Mann, Manuel D. Leonetti

Science. Author manuscript; available in PMC 2022 Sep 11.

Published in final edited form as: Science. 2022 Mar 11; 375(6585): eabi6983. Published online 2022 Mar 11. doi: 10.1126/science.abi6983

PMCID:: PMC9119736

Abstract Article PDF–3.3M

Select item 816503011.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 729373112.

RCAN1 Inhibits BACE2 Turnover by Attenuating Proteasome-Mediated BACE2 Degradation

Kaixin Qiu, Shuai Wang, Xin Wang, Fengting Wang, Yili Wu

Biomed Res Int. 2020; 2020: 1920789. Published online 2020 Jun 5. doi: 10.1155/2020/1920789

PMCID:: PMC7293731

Abstract Article PDF–931K

Select item 727263613.

The RCAN1.4-calcineurin/NFAT signaling pathway is essential for hypoxic adaption of intervertebral discs

Bao Huang, Yongqing He, Shengwen Li, Xiaoan Wei, Junhui Liu, Zhi Shan, Yue Huang, Jian Chen, Fengdong Zhao

Exp Mol Med. 2020 May; 52(5): 865–875. Published online 2020 May 29. doi: 10.1038/s12276-020-0441-x

PMCID:: PMC7272636

Abstract Article PDF–1.8M

Select item 662723214.

DSCR1‐mediated TET1 splicing regulates miR‐124 expression to control adult hippocampal neurogenesis

Chiyeol Choi, Taehoon Kim, Karen T Chang, Kyung‐Tai Min

EMBO J. 2019 Jul 15; 38(14): e101293. Published online 2019 Jun 11. doi: 10.15252/embj.2018101293

PMCID:: PMC6627232

Abstract Article PDF–4.3M

Select item 636214015.

DAP5 increases axonal outgrowth of hippocampal neurons by enhancing the cap-independent translation of DSCR1.4 mRNA

Ji-Young Seo, Youngseob Jung, Do-Yeon Kim, Hye Guk Ryu, Juhyun Lee, Sung Wook Kim, Kyong-Tai Kim

Cell Death Dis. 2019 Feb; 10(2): 49. Published online 2019 Jan 18. doi: 10.1038/s41419-018-1299-x

PMCID:: PMC6362140

Abstract Article PDF–2.1M

Select item 625180516.

Decreased activity of RCAN1.4 is a potential risk factor for congenital heart disease in a Han Chinese population

Liangping Cheng, Peiqiang Li, He Wang, Xueyan Yang, Huiming Zhou, Wufan Tao, Jie Tian, Hongyan Wang

Protein Cell. 2018 Dec; 9(12): 1039–1044. Published online 2018 Mar 28. doi: 10.1007/s13238-018-0525-8

PMCID:: PMC6251805

Article PDF–753K

Select item 567858117.

RNA-binding activity of TRIM25 is mediated by its PRY/SPRY domain and is required for ubiquitination

Nila Roy Choudhury, Gregory Heikel, Maryia Trubitsyna, Peter Kubik, Jakub Stanislaw Nowak, Shaun Webb, Sander Granneman, Christos Spanos, Juri Rappsilber, Alfredo Castello, Gracjan Michlewski

BMC Biol. 2017; 15: 105. Published online 2017 Nov 8. doi: 10.1186/s12915-017-0444-9

PMCID:: PMC5678581

Abstract Article PDF–3.2M

Select item 553161118.

Architecture of the human interactome defines protein communities and disease networks

Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper

Nature. Author manuscript; available in PMC 2017 Nov 17.

Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366

PMCID:: PMC5531611

Abstract Article PDF–2.7M

Select item 551162019.

RCAN1.4 regulates VEGFR-2 internalisation, cell polarity and migration in human microvascular endothelial cells

Ahmad F. Alghanem, Emma L. Wilkinson, Maxine S. Emmett, Mohammad A. Aljasir, Katherine Holmes, Beverley A. Rothermel, Victoria A. Simms, Victoria L. Heath, Michael J. Cross

Angiogenesis. 2017; 20(3): 341–358. Published online 2017 Mar 7. doi: 10.1007/s10456-017-9542-0

PMCID:: PMC5511620

Abstract Article PDF–13M

Select item 535532120.

The regulator of calcineurin 1 (RCAN1) inhibits nuclear factor kappaB signaling pathway and suppresses human malignant glioma cells growth

Xin Chen, Yuanyuan Hu, Shuo Wang, Xiulian Sun

Oncotarget. 2017 Feb 14; 8(7): 12003–12012. Published online 2017 Jan 4. doi: 10.18632/oncotarget.14479

PMCID:: PMC5355321

Abstract Article PDF–6.4M

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