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Select item 107001381.

The social and structural architecture of the yeast protein interactome

André C. Michaelis, Andreas-David Brunner, Maximilian Zwiebel, Florian Meier, Maximilian T. Strauss, Isabell Bludau, Matthias Mann

Nature. 2023; 624(7990): 192–200. Published online 2023 Nov 15. doi: 10.1038/s41586-023-06739-5

PMCID:: PMC10700138

Abstract Article PDF–20M

Select item 102333682.

A systematic proximity ligation approach to studying protein‐substrate specificity identifies the substrate spectrum of the Ssh1 translocon

Nir Cohen, Naama Aviram, Maya Schuldiner

EMBO J. 2023 Jun; 42(11): e113385. Published online 2023 Apr 19. doi: 10.15252/embj.2022113385

PMCID:: PMC10233368

Abstract Article PDF–1.2M

Select item 92098113.

New data and collaborations at the Saccharomyces Genome Database: updated reference genome, alleles, and the Alliance of Genome Resources

Stacia R Engel, Edith D Wong, Robert S Nash, Suzi Aleksander, Micheal Alexander, Eric Douglass, Kalpana Karra, Stuart R Miyasato, Matt Simison, Marek S Skrzypek, Shuai Weng, J Michael Cherry

Genetics. 2022 Apr; 220(4): iyab224. Published online 2021 Dec 13. doi: 10.1093/genetics/iyab224

PMCID:: PMC9209811

Abstract Article PDF–818K

Select item 70221884.

Structural analysis of the intrinsically disordered splicing factor Spp2 and its binding to the DEAH-box ATPase Prp2

Florian Hamann, Andreas Schmitt, Filippo Favretto, Romina Hofele, Piotr Neumann, ShengQi Xiang, Henning Urlaub, Markus Zweckstetter, Ralf Ficner

Proc Natl Acad Sci U S A. 2020 Feb 11; 117(6): 2948–2956. Published online 2020 Jan 23. doi: 10.1073/pnas.1907960117

PMCID:: PMC7022188

Abstract Article PDF–1.8M

Select item 57957875.

The RES complex is required for efficient transformation of the precatalytic B spliceosome into an activated B^act complex

Penghui Bao, Cindy L. Will, Henning Urlaub, Kum-Loong Boon, Reinhard Lührmann

Genes Dev. 2017 Dec 1; 31(23-24): 2416–2429. doi: 10.1101/gad.308163.117

PMCID:: PMC5795787

Abstract Article PDF–7.6M

Select item 57653596.

Genome-Wide Mapping of Decay Factor–mRNA Interactions in Yeast Identifies Nutrient-Responsive Transcripts as Targets of the Deadenylase Ccr4

Jason E. Miller, Liye Zhang, Haoyang Jiang, Yunfei Li, B. Franklin Pugh, Joseph C. Reese

G3 (Bethesda) 2018 Jan; 8(1): 315–330. Published online 2017 Nov 20. doi: 10.1534/g3.117.300415

PMCID:: PMC5765359

Abstract Article PDF–2.2M

Select item 49868977.

A protein map of the yeast activated spliceosome as obtained by electron microscopy

Chengfu Sun, Norbert Rigo, Patrizia Fabrizio, Berthold Kastner, Reinhard Lührmann

RNA. 2016 Sep; 22(9): 1427–1440. doi: 10.1261/rna.057778.116

PMCID:: PMC4986897

Abstract Article PDF–1.3M

Select item 42857748.

The G-patch protein Spp2 couples the spliceosome-stimulated ATPase activity of the DEAH-box protein Prp2 to catalytic activation of the spliceosome

Zbigniew Warkocki, Cornelius Schneider, Sina Mozaffari-Jovin, Jana Schmitzová, Claudia Höbartner, Patrizia Fabrizio, Reinhard Lührmann

Genes Dev. 2015 Jan 1; 29(1): 94–107. doi: 10.1101/gad.253070.114

PMCID:: PMC4285774

Abstract Article PDF–1.1M

Select item 38672669.

Biased Brownian ratcheting leads to pre-mRNA remodeling and capture prior to first-step splicing

Ramya Krishnan, Mario Blanco, Matthew Kahlscheuer, John Abelson, Christine Guthrie, Nils G. Walter

Nat Struct Mol Biol. Author manuscript; available in PMC 2014 Jun 1.

Published in final edited form as: Nat Struct Mol Biol. 2013 Dec; 20(12): 1450–1457. Published online 2013 Nov 17. doi: 10.1038/nsmb.2704

PMCID:: PMC3867266

Abstract Article PDF–1.7M

Select item 356498710.

Saccharomyces cerevisiae Genetics Predicts Candidate Therapeutic Genetic Interactions at the Mammalian Replication Fork

Derek M. van Pel, Peter C. Stirling, Sean W. Minaker, Payal Sipahimalani, Philip Hieter

G3 (Bethesda) 2013 Feb; 3(2): 273–282. Published online 2013 Feb 1. doi: 10.1534/g3.112.004754

PMCID:: PMC3564987

Abstract Article PDF–2.3M

Select item 328593311.

La-motif–dependent mRNA association with Slf1 promotes copper detoxification in yeast

Luca Schenk, Dominik M. Meinel, Katja Strässer, André P. Gerber

RNA. 2012 Mar; 18(3): 449–461. doi: 10.1261/rna.028506.111

PMCID:: PMC3285933

Abstract Article PDF–812K

Select item 309130112.

Defining potentially conserved RNA regulons of homologous zinc-finger RNA-binding proteins

Tanja Scherrer, Christian Femmer, Ralph Schiess, Ruedi Aebersold, André P Gerber

Genome Biol. 2011; 12(1): R3. Published online 2011 Jan 13. doi: 10.1186/gb-2011-12-1-r3

PMCID:: PMC3091301

Abstract Article PDF–1.3M

Select item 282291713.

Release of SF3 from the intron branchpoint activates the first step of pre-mRNA splicing

Rea M. Lardelli, James X. Thompson, John R. Yates, III, Scott W. Stevens

RNA. 2010 Mar; 16(3): 516–528. doi: 10.1261/rna.2030510

PMCID:: PMC2822917

Abstract Article PDF–1.1M

Select item 278735314.

Purification of Nuclear Poly(A)-binding Protein Nab2 Reveals Association with the Yeast Transcriptome and a Messenger Ribonucleoprotein Core Structure

Julien Batisse, Claire Batisse, Aidan Budd, Bettina Böttcher, Ed Hurt

J Biol Chem. 2009 Dec 11; 284(50): 34911–34917. Published online 2009 Oct 19. doi: 10.1074/jbc.M109.062034

PMCID:: PMC2787353

Abstract Article PDF–3.8M

Select item 277966615.

A systematic characterization of Cwc21, the yeast ortholog of the human spliceosomal protein SRm300

May Khanna, Harm Van Bakel, Xinyi Tang, John A. Calarco, Tomas Babak, Grace Guo, Andrew Emili, Jack F. Greenblatt, Timothy R. Hughes, Nevan J. Krogan, Benjamin J. Blencowe

RNA. 2009 Dec; 15(12): 2174–2185. doi: 10.1261/rna.1790509