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Select item 104840801.

MyD88和TICAM1基因多态性及其交互作用与儿童社区获得性肺炎的关联研究

杨勇, 杨绥宇, 陈宗波, 刘俐

Zhongguo Dang Dai Er Ke Za Zhi. 2023 Aug 15; 25(8): 791–799. Chinese. doi: 10.7499/j.issn.1008-8830.2303062

PMCID:: PMC10484080

Abstract Article PDF–1.1M

Select item 100454392.

Bacterial vesicles block viral replication in macrophages via TLR4-TRIF-axis

Jeff Bierwagen, Marie Wiegand, Katrin Laakmann, Olga Danov, Hannah Limburg, Stefanie Muriel Herbel, Thomas Heimerl, Jens Dorna, Danny Jonigk, Christian Preußer, Wilhelm Bertrams, Armin Braun, Katherina Sewald, Leon N. Schulte, Stefan Bauer, Elke Pogge von Strandmann, Eva Böttcher-Friebertshäuser, Bernd Schmeck, Anna Lena Jung

Cell Commun Signal. 2023; 21: 65. Published online 2023 Mar 28. doi: 10.1186/s12964-023-01086-4

PMCID:: PMC10045439

Abstract Article PDF–3.6M

Select item 95702123.

PAUF Induces Migration of Human Pancreatic Cancer Cells Exclusively via the TLR4/MyD88/NF-κB Signaling Pathway

So Eun Youn, Fen Jiang, Hye Yun Won, Da Eun Hong, Tae Heung Kang, Yun-Yong Park, Sang Seok Koh

Int J Mol Sci. 2022 Oct; 23(19): 11414. Published online 2022 Sep 27. doi: 10.3390/ijms231911414

PMCID:: PMC9570212

Abstract Article PDF–3.9M

Select item 92581864.

Pathogenic Leptospires Limit Dendritic Cell Activation Through Avoidance of TLR4 and TRIF Signaling

Julie Cagliero, Frédérique Vernel-Pauillac, Gerald Murray, Ben Adler, Mariko Matsui, Catherine Werts

Front Immunol. 2022; 13: 911778. Published online 2022 Jun 22. doi: 10.3389/fimmu.2022.911778

PMCID:: PMC9258186

Abstract Article PDF–2.7M

Select item 86957225.

MicroRNA-181b-2 and MicroRNA-21-1 Negatively Regulate NF-κB and IRF3-Mediated Innate Immune Responses via Targeting TRIF in Teleost

Yuena Sun, Lei Zhang, Ling Hong, Weiwei Zheng, Junxia Cui, Xuezhu Liu, Tianjun Xu

Front Immunol. 2021; 12: 734520. Published online 2021 Dec 9. doi: 10.3389/fimmu.2021.734520

PMCID:: PMC8695722

Abstract Article PDF–6.2M

Select item 81650306.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 79045557.

TLR4 and CD14 trafficking and its influence on LPS-induced pro-inflammatory signaling

Anna Ciesielska, Marta Matyjek, Katarzyna Kwiatkowska

Cell Mol Life Sci. 2021 Feb; 78(4): 1233–1261. Published online 2020 Oct 15. doi: 10.1007/s00018-020-03656-y

PMCID:: PMC7904555

Abstract Article PDF–2.4M

Select item 75460078.

Redox DAPK1 destabilizes Pellino1 to govern inflammation-coupling tubular damage during septic AKI

Bang-Chuan Hu, Guo-Hua Wu, Zi-Qiang Shao, Yang Zheng, Jin-Quan Liu, Run Zhang, Jun Hong, Xiang-Hong Yang, Ren-Hua Sun, Shi-Jing Mo

Theranostics. 2020; 10(25): 11479–11496. Published online 2020 Sep 15. doi: 10.7150/thno.49870

PMCID:: PMC7546007

Abstract Article PDF–3.4M

Select item 73220679.

RIG-I regulates myeloid differentiation by promoting TRIM25-mediated ISGylation

Song-Fang Wu, Li Xia, Xiao-Dong Shi, Yu-Jun Dai, Wei-Na Zhang, Jun-Mei Zhao, Wu Zhang, Xiang-Qin Weng, Jing Lu, Huang-Ying Le, Sheng-ce Tao, Jiang Zhu, Zhu Chen, Yue-Ying Wang, Saijuan Chen

Proc Natl Acad Sci U S A. 2020 Jun 23; 117(25): 14395–14404. Published online 2020 Jun 8. doi: 10.1073/pnas.1918596117

PMCID:: PMC7322067

Abstract Article PDF–2.7M

Select item 710142510.

New insights in acetaminophen toxicity: HMGB1 contributes by itself to amplify hepatocyte necrosis in vitro through the TLR4-TRIF-RIPK3 axis

Charlotte Minsart, Claire Liefferinckx, Arnaud Lemmers, Cindy Dressen, Eric Quertinmont, Isabelle Leclercq, Jacques Devière, Richard Moreau, Thierry Gustot

Sci Rep. 2020; 10: 5557. Published online 2020 Mar 27. doi: 10.1038/s41598-020-61270-1

PMCID:: PMC7101425

Abstract Article PDF–1.8M

Select item 702064611.

Priming Phosphorylation of TANK-Binding Kinase 1 by IκB Kinase β Is Essential in Toll-Like Receptor 3/4 Signaling

Hiroto Abe, Junko Satoh, Yutaro Shirasaka, Amane Kogure, Hiroki Kato, Shinji Ito, Takashi Fujita

Mol Cell Biol. 2020 Mar; 40(5): e00509-19. Prepublished online 2019 Dec 9. Published online 2020 Feb 12. doi: 10.1128/MCB.00509-19

PMCID:: PMC7020646

Abstract Article PDF–2.6M

Select item 689986612.

RNF144B inhibits LPS‐induced inflammatory responses via binding TBK1

Zhen Zhang, Luoyan Zhang, Bin Wang, Xiaoxiao Zhu, Lin Zhao, Chu Chu, Qiang Guo, Ran Wei, Xunqiang Yin, Yunhong Zhang, Xia Li

J Leukoc Biol. 2019 Dec; 106(6): 1303–1311. Published online 2019 Sep 11. doi: 10.1002/JLB.2A0819-055R

PMCID:: PMC6899866

Abstract Article PDF–2.9M

Select item 673940413.

Regulation of TRIF-mediated innate immune response by K27-linked polyubiquitination and deubiquitination

Xin Wu, Caoqi Lei, Tian Xia, Xuan Zhong, Qing Yang, Hong-Bing Shu

Nat Commun. 2019; 10: 4115. Published online 2019 Sep 11. doi: 10.1038/s41467-019-12145-1

PMCID:: PMC6739404

Abstract Article PDF–1.8M

Select item 588149714.

SLAMF1 is required for TLR4-mediated TRAM-TRIF–dependent signaling in human macrophages

Maria Yurchenko, Astrid Skjesol, Liv Ryan, Gabriel Mary Richard, Richard Kumaran Kandasamy, Ninghai Wang, Cox Terhorst, Harald Husebye, Terje Espevik

J Cell Biol. 2018 Apr 2; 217(4): 1411–1429. doi: 10.1083/jcb.201707027

PMCID:: PMC5881497

Abstract Article PDF–3.0M

Select item 572536315.

TRIM56 Suppresses Multiple Myeloma Progression by Activating TLR3/TRIF Signaling

Ying Chen, Jing Zhao, Dengzhe Li, Jinxia Hao, Pengcheng He, Huaiyu Wang, Mei Zhang

Yonsei Med J. 2018 Jan 1; 59(1): 43–50. Published online 2017 Nov 29. doi: 10.3349/ymj.2018.59.1.43

PMCID:: PMC5725363

Abstract Article PDF–902K

Select item 567858116.

RNA-binding activity of TRIM25 is mediated by its PRY/SPRY domain and is required for ubiquitination

Nila Roy Choudhury, Gregory Heikel, Maryia Trubitsyna, Peter Kubik, Jakub Stanislaw Nowak, Shaun Webb, Sander Granneman, Christos Spanos, Juri Rappsilber, Alfredo Castello, Gracjan Michlewski

BMC Biol. 2017; 15: 105. Published online 2017 Nov 8. doi: 10.1186/s12915-017-0444-9

PMCID:: PMC5678581

Abstract Article PDF–3.2M

Select item 553393317.

Seneca Valley Virus Suppresses Host Type I Interferon Production by Targeting Adaptor Proteins MAVS, TRIF, and TANK for Cleavage

Suhong Qian, Wenchun Fan, Tingting Liu, Mengge Wu, Huawei Zhang, Xiaofang Cui, Yun Zhou, Junjie Hu, Shaozhong Wei, Huanchun Chen, Xiangmin Li, Ping Qian

J Virol. 2017 Aug 15; 91(16): e00823-17. Prepublished online 2017 May 31. Published online 2017 Jul 27. doi: 10.1128/JVI.00823-17

PMCID:: PMC5533933

Abstract Article PDF–3.0M

Select item 553161118.

Architecture of the human interactome defines protein communities and disease networks

Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper

Nature. Author manuscript; available in PMC 2017 Nov 17.

Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366