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Select item 108208261.

Interrogation and validation of the interactome of neuronal Munc18-interacting Mint proteins with AlphaFold2

Saroja Weeratunga, Rachel S. Gormal, Meihan Liu, Denaye Eldershaw, Emma K. Livingstone, Anusha Malapaka, Tristan P. Wallis, Adekunle T. Bademosi, Anmin Jiang, Michael D. Healy, Frederic A. Meunier, Brett M. Collins

J Biol Chem. 2024 Jan; 300(1): 105541. Published online 2023 Dec 9. doi: 10.1016/j.jbc.2023.105541

PMCID:: PMC10820826

Abstract Article PDF–5.6M

Select item 93485762.

Chr21 protein–protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer’s disease

Julia Viard, Yann Loe-Mie, Rachel Daudin, Malik Khelfaoui, Christine Plancon, Anne Boland, Francisco Tejedor, Richard L Huganir, Eunjoon Kim, Makoto Kinoshita, Guofa Liu, Volker Haucke, Thomas Moncion, Eugene Yu, Valérie Hindie, Henri Bléhaut, Clotilde Mircher, Yann Herault, Jean-François Deleuze, Jean-Christophe Rain, Michel Simonneau, Aude-Marie Lepagnol-Bestel

Life Sci Alliance. 2022 Dec; 5(12): e202101205. Published online 2022 Aug 1. doi: 10.26508/lsa.202101205

PMCID:: PMC9348576

Abstract Article PDF–3.0M

Select item 88570493.

Tau interactome maps synaptic and mitochondrial processes associated with neurodegeneration

Tara E. Tracy, Jesus Madero-Pérez, Danielle L. Swaney, Timothy S. Chang, Michelle Moritz, Csaba Konrad, Michael E. Ward, Erica Stevenson, Ruth Hüttenhain, Grant Kauwe, Maria Mercedes, Lauren Sweetland-Martin, Xu Chen, Sue-Ann Mok, Man Ying Wong, Maria Telpoukhovskaia, Sang-Won Min, Chao Wang, Peter Dongmin Sohn, Jordie Martin, Yungui Zhou, Wenjie Luo, John Q. Trojanowski, Virginia M.Y. Lee, Shiaoching Gong, Giovanni Manfredi, Giovanni Coppola, Nevan J. Krogan, Daniel H. Geschwind, Li Gan

Cell. Author manuscript; available in PMC 2022 Feb 19.

Published in final edited form as: Cell. 2022 Feb 17; 185(4): 712–728.e14. Published online 2022 Jan 20. doi: 10.1016/j.cell.2021.12.041

PMCID:: PMC8857049

Abstract Article PDF–3.6M

Select item 85167924.

RNA sequencing and functional studies of patient-derived cells reveal that neurexin-1 and regulators of this pathway are associated with poor outcomes in Ewing sarcoma

Elizabeth Ann Roundhill, Mariona Chicon-Bosch, Lee Jeys, Michael Parry, Kenneth S Rankin, Alastair Droop, Susan Ann Burchill

Cell Oncol (Dordr) 2021; 44(5): 1065–1085. Published online 2021 Aug 17. doi: 10.1007/s13402-021-00619-8

PMCID:: PMC8516792

Abstract Article PDF–5.2M

Select item 82501315.

Host PDZ‐containing proteins targeted by SARS‐CoV‐2

Célia Caillet‐Saguy, Fabien Durbesson, Veronica V. Rezelj, Gergö Gogl, Quang Dinh Tran, Jean‐Claude Twizere, Marco Vignuzzi, Renaud Vincentelli, Nicolas Wolff

FEBS J. 2021 Sep; 288(17): 5148–5162. Published online 2021 May 1. doi: 10.1111/febs.15881

PMCID:: PMC8250131

Abstract Article PDF–1.4M

Select item 81650306.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 67860357.

Molecular Analysis of the X11–mLin-2/CASK Complex in Brain

Jean-Paul Borg, Manuel O. Lõpez-Figueroa, Mylène de Taddèo-Borg, Dallas E. Kroon, R. Scott Turner, Stanley J. Watson, Ben Margolis

J Neurosci. 1999 Feb 15; 19(4): 1307–1316. doi: 10.1523/JNEUROSCI.19-04-01307.1999

PMCID:: PMC6786035

Abstract Article PDF–506K

Select item 67579968.

Regulation of APP-Dependent Transcription Complexes by Mint/X11s: Differential Functions of Mint Isoforms

Thomas Biederer, Xinwei Cao, Thomas C. Südhof, Xinran Liu

J Neurosci. 2002 Sep 1; 22(17): 7340–7351. doi: 10.1523/JNEUROSCI.22-17-07340.2002

PMCID:: PMC6757996

Abstract Article PDF–1.0M

Select item 67421389.

KIF17 Dynamics and Regulation of NR2B Trafficking in Hippocampal Neurons

Laurent Guillaud, Mitsutoshi Setou, Nobutaka Hirokawa

J Neurosci. 2003 Jan 1; 23(1): 131–140. doi: 10.1523/JNEUROSCI.23-01-00131.2003

Correction in:: J Neurosci. 2003 Feb 15; 23(4): 0.

PMCID:: PMC6742138

Abstract Article PDF–792K

Select item 669413210.

HENA, heterogeneous network-based data set for Alzheimer’s disease

Elena Sügis, Jerome Dauvillier, Anna Leontjeva, Priit Adler, Valerie Hindie, Thomas Moncion, Vincent Collura, Rachel Daudin, Yann Loe-Mie, Yann Herault, Jean-Charles Lambert, Henning Hermjakob, Tal Pupko, Jean-Christophe Rain, Ioannis Xenarios, Jaak Vilo, Michel Simonneau, Hedi Peterson

Sci Data. 2019; 6: 151. Published online 2019 Aug 14. doi: 10.1038/s41597-019-0152-0

PMCID:: PMC6694132

Abstract Article PDF–2.8M

Select item 667252811.

Apolipoprotein Receptor 2 and X11α/β Mediate Apolipoprotein E-Induced Endocytosis of Amyloid-β Precursor Protein and β-Secretase, Leading to Amyloid-β Production

Xiangyuan He, Kathleen Cooley, Charlotte H. Y. Chung, Nassrin Dashti, Jordan Tang

J Neurosci. 2007 Apr 11; 27(15): 4052–4060. doi: 10.1523/JNEUROSCI.3993-06.2007

PMCID:: PMC6672528

Abstract Article PDF–462K

Select item 553161112.

Architecture of the human interactome defines protein communities and disease networks

Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper

Nature. Author manuscript; available in PMC 2017 Nov 17.

Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366

PMCID:: PMC5531611

Abstract Article PDF–2.7M

Select item 498202213.

Multisite tyrosine phosphorylation of the N‐terminus of Mint1/X11α by Src kinase regulates the trafficking of amyloid precursor protein

Christopher J. R. Dunning, Hannah L. Black, Katie L. Andrews, Elizabeth C. Davenport, Michael Conboy, Sangeeta Chawla, Adam A. Dowle, David Ashford, Jerry R. Thomas, Gareth J. O. Evans

J Neurochem. 2016 May; 137(4): 518–527. Published online 2016 Mar 1. doi: 10.1111/jnc.13571

PMCID:: PMC4982022

Abstract Article PDF–2.0M

Select item 480585514.

Substrate-Trapped Interactors of PHD3 and FIH Cluster in Distinct Signaling Pathways

Javier Rodriguez, Ruth Pilkington, Amaya Garcia Munoz, Lan K. Nguyen, Nora Rauch, Susan Kennedy, Naser Monsefi, Ana Herrero, Cormac T. Taylor, Alex von Kriegsheim

Cell Rep. 2016 Mar 22; 14(11): 2745–2760. Published online 2016 Mar 10. doi: 10.1016/j.celrep.2016.02.043

PMCID:: PMC4805855

Abstract Article PDF–4.6M

Select item 461721115.

The BioPlex Network: A Systematic Exploration of the Human Interactome

Edward L. Huttlin, Lily Ting, Raphael J. Bruckner, Fana Gebreab, Melanie P. Gygi, John Szpyt, Stanley Tam, Gabriela Zarraga, Greg Colby, Kurt Baltier, Rui Dong, Virginia Guarani, Laura Pontano Vaites, Alban Ordureau, Ramin Rad, Brian K. Erickson, Martin Wühr, Joel Chick, Bo Zhai, Deepak Kolippakkam, Julian Mintseris, Robert A. Obar, Tim Harris, Spyros Artavanis-Tsakonas, Mathew E. Sowa, Pietro DeCamilli, Joao A. Paulo, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2016 Jul 16.

Published in final edited form as: Cell. 2015 Jul 16; 162(2): 425–440. doi: 10.1016/j.cell.2015.06.043

PMCID:: PMC4617211

Abstract Article PDF–2.2M

Select item 414089416.

Mint Proteins Are Required for Synaptic Activity-dependent Amyloid Precursor Protein (APP) Trafficking and Amyloid β Generation

Sarah E. Sullivan, Gregory M. Dillon, Josefa M. Sullivan, Angela Ho

J Biol Chem. 2014 May 30; 289(22): 15374–15383. Published online 2014 Apr 17. doi: 10.1074/jbc.M113.541003

PMCID:: PMC4140894

Abstract Article PDF–2.3M

Select item 366784417.

A New Mint1 Isoform, but Not the Conventional Mint1, Interacts with the Small GTPase Rab6

Anika Thyrock, Edith Ossendorf, Martin Stehling, Mark Kail, Tanja Kurtz, Gottfried Pohlentz, Dieter Waschbüsch, Simone Eggert, Etienne Formstecher, Johannes Müthing, Klaus Dreisewerd, Stefan Kins, Bruno Goud, Angelika Barnekow

PLoS One. 2013; 8(5): e64149. Published online 2013 May 30. doi: 10.1371/journal.pone.0064149

PMCID:: PMC3667844

Abstract Article PDF–5.6M

Select item 330976318.

Autoinhibition of Mint1 adaptor protein regulates amyloid precursor protein binding and processing

Maria F. Matos, Yibin Xu, Irina Dulubova, Zbyszek Otwinowski, John M. Richardson, Diana R. Tomchick, Josep Rizo, Angela Ho

Proc Natl Acad Sci U S A. 2012 Mar 6; 109(10): 3802-3807. Published online 2012 Feb 21. doi: 10.1073/pnas.1119075109

PMCID:: PMC3309763

Abstract Article PDF–1.4M

Select item 330753319.

Synaptic Targeting of N-Type Calcium Channels in Hippocampal Neurons

Anton Maximov, Ilya Bezprozvanny

J Neurosci. 2002 Aug 15; 22(16): 6939–6952. doi: 10.1523/JNEUROSCI.22-16-06939.2002

PMCID:: PMC3307533

Abstract Article PDF–1.0M

Select item 317805920.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

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