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Items: 1 to 20 of 28

1.
LHPP Inhibits the Viability, Migration, and Proliferation of PDAC Cells and Significantly Affects the Expression of SDC1 and S100p
Zhaozhi Xia, Shuchao Zhao, Xin Gao, Hongrui Sun, Faji Yang, Huaqiang Zhu, Hengjun Gao, Jun Lu, Xu Zhou
Technol Cancer Res Treat. 2023; 22: 15330338231177807. Published online 2023 Jun 15. doi: 10.1177/15330338231177807
PMCID:
PMC10278439
AbstractArticlePDF–2.9M
2.
A dual-activity topoisomerase complex regulates mRNA translation and turnover
Shuaikun Su, Yutong Xue, Alexei Sharov, Yongqing Zhang, Seung Kyu Lee, Jennifer L Martindale, Wen Li, Wai Lim Ku, Keji Zhao, Supriyo De, Weiping Shen, Payel Sen, Myriam Gorospe, Dongyi Xu, Weidong Wang
Nucleic Acids Res. 2022 Jul 8; 50(12): 7013–7033. Published online 2022 Jun 24. doi: 10.1093/nar/gkac538
PMCID:
PMC9262614
AbstractArticlePDF–3.6M
3.
As a Novel Tumor Suppressor, LHPP Promotes Apoptosis by Inhibiting the PI3K/AKT Signaling Pathway in Oral Squamous Cell Carcinoma
Shanshan Liu, Wenzhen Gao, Yupu Lu, Qin Zhou, Rongjian Su, Tomoka Hasegawa, Juan Du, Minqi Li
Int J Biol Sci. 2022; 18(2): 491–506. Published online 2022 Jan 1. doi: 10.7150/ijbs.66841
PMCID:
PMC8741864
AbstractArticlePDF–3.2M
4.
Three LHPP gene‐targeting co‐expressed microRNAs (microRNA‐765, microRNA‐21, and microRNA‐144) promote proliferation, epithelial‐mesenchymal transition, invasion, and are independent prognostic biomarkers in renal cell carcinomas patients
Kexin Meng, Zongda Li, Xiaoying Cui
J Clin Lab Anal. 2021 Dec; 35(12): e24077. Published online 2021 Oct 26. doi: 10.1002/jcla.24077
PMCID:
PMC8649365
AbstractArticlePDF–1.6M
5.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
6.
LHPP impedes energy metabolism by inducing ubiquitin-mediated degradation of PKM2 in glioblastoma
Wen-Jin Chen, Li-Hua Chen, Ji Wang, Zhao-Tao Wang, Cui-Ying Wu, Kai Sun, Bo-Yun Ding, Ning Liu, Ru-Xiang Xu
Am J Cancer Res. 2021; 11(4): 1369–1390. Published online 2021 Apr 15.
PMCID:
PMC8085851
AbstractArticlePDF–6.1M
7.
LHPP Inhibits the Proliferation and Metastasis of Renal Cell Carcinoma
Xiaoting Zhang, Huaning Kang, Jing Xiao, Benyan Shi, Xiaofeng Li, Guihong Chen
Biomed Res Int. 2020; 2020: 7020924. Published online 2020 Dec 22. doi: 10.1155/2020/7020924
PMCID:
PMC7772040
AbstractArticlePDF–2.5M
8.
TRIM27 Functions as a Novel Oncogene in Non-Triple-Negative Breast Cancer by Blocking Cellular Senescence through p21 Ubiquitination
Li Xing, Xiaolong Tang, Kaikai Wu, Xiong Huang, Yi Yi, Jinliang Huan
Mol Ther Nucleic Acids. 2020 Dec 4; 22: 910–923. Published online 2020 Oct 15. doi: 10.1016/j.omtn.2020.10.012
PMCID:
PMC7666371
AbstractArticlePDF–4.6M
9.
Genome‐wide association study of chemotherapeutic agent‐induced severe neutropenia/leucopenia for patients in Biobank Japan
Siew‐Kee Low, Suyoun Chung, Atsushi Takahashi, Hitoshi Zembutsu, Taisei Mushiroda, Michiaki Kubo, Yusuke Nakamura
Cancer Sci. 2013 Aug; 104(8): 1074–1082. Published online 2013 Jun 10. doi: 10.1111/cas.12186
PMCID:
PMC7657179
AbstractArticlePDF–225K
10.
LHPP inhibits hepatocellular carcinoma cell growth and metastasis
Lijuan Liao, Deyu Duan, Yanfeng Liu, Liang Chen
Cell Cycle. 2020; 19(14): 1846–1854. Published online 2020 Jun 24. doi: 10.1080/15384101.2020.1783472
PMCID:
PMC7469522
AbstractArticlePDF–4.2M
11.
A reference map of the human binary protein interactome
Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood
Nature. Author manuscript; available in PMC 2020 Oct 8.
Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x
PMCID:
PMC7169983
AbstractArticlePDF–5.4M
12.
LHPP suppresses proliferation, migration, and invasion and promotes apoptosis in pancreatic cancer
Fahong Wu, Yanling Chen, Jinhai Zhu
Biosci Rep. 2020 Mar 27; 40(3): BSR20194142. Published online 2020 Mar 27. doi: 10.1042/BSR20194142
PMCID:
PMC7103587
AbstractArticlePDF–1.2M
13.
Clinical value of LHPP‐associated microRNAs combined with protein induced by vitamin K deficiency or antagonist‐II in the diagnosis of alpha‐fetoprotein‐negative hepatocellular carcinoma
Zeyu Tian, Tanbo Yu, Hongyan Wei, Ning Ning
J Clin Lab Anal. 2020 Feb; 34(2): e23071. Published online 2019 Nov 6. doi: 10.1002/jcla.23071
PMCID:
PMC7031545
AbstractArticlePDF–1.1M
14.
Tumor suppressor LHPP regulates the proliferation of colorectal cancer cells via the PI3K/AKT pathway
Bin Hou, Wenhan Li, Jianhui Li, Jia Ma, Peng Xia, Zhao Liu, Qingnuo Zeng, Xin Zhang, Dongmin Chang
Oncol Rep. 2020 Feb; 43(2): 536–548. Published online 2019 Dec 20. doi: 10.3892/or.2019.7442
PMCID:
PMC6967159
AbstractArticlePDF–2.1M
15.
LHPP suppresses bladder cancer cell proliferation and growth via inactivating AKT/p65 signaling pathway
Yansheng Li, Xin Zhang, Xiaoguang Zhou, Xiaodong Zhang
Biosci Rep. 2019 Jul 31; 39(7): BSR20182270. Prepublished online 2019 Jul 1. Published online 2019 Jul 30. doi: 10.1042/BSR20182270
PMCID:
PMC6667728
AbstractArticlePDF–1.8M
16.
The protein histidine phosphatase LHPP is a tumour suppressor
Sravanth K. Hindupur, Marco Colombi, Stephen R. Fuhs, Matthias S. Matter, Yakir Guri, Kevin Adam, Marion Cornu, Salvatore Piscuoglio, Charlotte K. Y. Ng, Charles Betz, Dritan Liko, Luca Quagliata, Suzette Moes, Paul Jenoe, Luigi M. Terracciano, Markus H. Heim, Tony Hunter, Michael N. Hall
Nature. Author manuscript; available in PMC 2019 Feb 15.
Published in final edited form as: Nature. 2018 Mar 29; 555(7698): 678–682. Published online 2018 Mar 21. doi: 10.1038/nature26140
PMCID:
PMC6376988
AbstractArticlePDF–2.6M
17.
Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing
Teng Fei, Yiwen Chen, Tengfei Xiao, Wei Li, Laura Cato, Peng Zhang, Maura B. Cotter, Michaela Bowden, Rosina T. Lis, Shuang G. Zhao, Qiu Wu, Felix Y. Feng, Massimo Loda, Housheng Hansen He, X. Shirley Liu, Myles Brown
Proc Natl Acad Sci U S A. 2017 Jun 27; 114(26): E5207–E5215. Published online 2017 Jun 13. doi: 10.1073/pnas.1617467114
PMCID:
PMC5495225
AbstractArticlePDF–1.3M
18.
The Interplay Between Risky Sexual Behaviors and Alcohol Dependence: Genome-Wide Association and Neuroimaging Support for LHPP as a Risk Gene
Renato Polimanti, Qian Wang, Shashwath A Meda, Krishna T Patel, Godfrey D Pearlson, Hongyu Zhao, Lindsay A Farrer, Henry R Kranzler, Joel Gelernter
Neuropsychopharmacology. 2017 Feb; 42(3): 598–605. Prepublished online 2016 Aug 17. Published online 2016 Sep 14. doi: 10.1038/npp.2016.153
PMCID:
PMC5240175
AbstractArticlePDF–253K
19.
Genome-wide association analyses identify new susceptibility loci for oral cavity and pharyngeal cancer
Corina Lesseur, Brenda Diergaarde, Andrew F Olshan, Victor Wünsch-Filho, Andrew R Ness, Geoffrey Liu, Martin Lacko, José Eluf-Neto, Silvia Franceschi, Pagona Lagiou, Gary J Macfarlane, Lorenzo Richiardi, Stefania Boccia, Jerry Polesel, Kristina Kjaerheim, David Zaridze, Mattias Johansson, Ana M Menezes, Maria Paula Curado, Max Robinson, Wolfgang Ahrens, Cristina Canova, Ariana Znaor, Xavier Castellsagué, David I Conway, Ivana Holcátová, Dana Mates, Marta Vilensky, Claire M Healy, Neonila Szeszenia-Dabrowska, Eleonóra Fabiánová, Jolanta Lissowska, Jennifer R Grandis, Mark C Weissler, Eloiza H Tajara, Fabio D Nunes, Marcos B de Carvalho, Steve Thomas, Rayjean J Hung, Wilbert H M Peters, Rolando Herrero, Gabriella Cadoni, H Bas Bueno-de-Mesquita, Annika Steffen, Antonio Agudo, Oxana Shangina, Xiangjun Xiao, Valérie Gaborieau, Amélie Chabrier, Devasena Anantharaman, Paolo Boffetta, Christopher I Amos, James D McKay, Paul Brennan
Nat Genet. Author manuscript; available in PMC 2017 Apr 17.
Published in final edited form as: Nat Genet. 2016 Dec; 48(12): 1544–1550. Published online 2016 Oct 17. doi: 10.1038/ng.3685
PMCID:
PMC5131845
AbstractArticlePDF–1.6M
20.
Relationship between the LHPP Gene Polymorphism and Resting-State Brain Activity in Major Depressive Disorder
Lingling Cui, Xiaohong Gong, Yanqing Tang, Lingtao Kong, Miao Chang, Haiyang Geng, Ke Xu, Fei Wang
Neural Plast. 2016; 2016: 9162590. Published online 2016 Oct 23. doi: 10.1155/2016/9162590
PMCID:
PMC5097818
AbstractArticlePDF–1.5M

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