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Select item 112342061.

METTL3 regulates thyroid cancer differentiation and chemosensitivity by modulating PAX8

Ning Kang, Zewei Zhao, Zhongyu Wang, Junya Ning, Huijuan Wang, Wei Zhang, Xianhui Ruan, Ming Gao, Xiangqian Zheng

Int J Biol Sci. 2024; 20(9): 3426–3441. Published online 2024 Jun 17. doi: 10.7150/ijbs.84797

PMCID:: PMC11234206

Abstract Article PDF–10M

Select item 101089022.

Single-cell transcriptomics identifies gene expression networks driving differentiation and tumorigenesis in the human fallopian tube

Huy Q. Dinh, Xianzhi Lin, Forough Abbasi, Robbin Nameki, Marcela Haro, Claire E. Olingy, Heidi Chang, Lourdes Hernandez, Simon A. Gayther, Kelly N. Wright, Paul-Joseph Aspuria, Beth Y. Karlan, Rosario I. Corona, Andrew Li, B.J. Rimel, Matthew T. Siedhoff, Fabiola Medeiros, Kate Lawrenson

Cell Rep. Author manuscript; available in PMC 2023 Apr 17.

Published in final edited form as: Cell Rep. 2021 Apr 13; 35(2): 108978. doi: 10.1016/j.celrep.2021.108978

PMCID:: PMC10108902

Abstract Article PDF–2.9M

Select item 95924973.

Significance analysis of PAX8 expression in endometrial carcinoma

Shan Hu, Hua Gan, Fengmei Yang

Medicine (Baltimore) 2022 Oct 21; 101(42): e31159. Published online 2022 Oct 21. doi: 10.1097/MD.0000000000031159

PMCID:: PMC9592497

Abstract Article PDF–1.6M

Select item 92428604.

The renal lineage factor PAX8 controls oncogenic signalling in kidney cancer

Saroor A. Patel, Shoko Hirosue, Paulo Rodrigues, Erika Vojtasova, Emma K. Richardson, Jianfeng Ge, Saiful E. Syafruddin, Alyson Speed, Evangelia K. Papachristou, David Baker, David Clarke, Stephenie Purvis, Ludovic Wesolowski, Anna Dyas, Leticia Castillon, Veronica Caraffini, Dóra Bihary, Cissy Yong, David J. Harrison, Grant D. Stewart, Mitchell J. Machiela, Mark P. Purdue, Stephen J. Chanock, Anne Y. Warren, Shamith A. Samarajiwa, Jason S. Carroll, Sakari Vanharanta

Nature. 2022; 606(7916): 999–1006. Published online 2022 Jun 8. doi: 10.1038/s41586-022-04809-8

PMCID:: PMC9242860

Abstract Article PDF–20M

Select item 91353815.

The transcription factor PAX8 promotes angiogenesis in ovarian cancer through interaction with SOX17

Daniele Chaves-Moreira, Marilyn A. Mitchell, Cristina Arruza, Priyanka Rawat, Simone Sidoli, Robbin Nameki, Jessica Reddy, Rosario I. Corona, Lena K. Afeyan, Isaac A. Klein, Sisi Ma, Boris Winterhoff, Gottfried E. Konecny, Benjamin A. Garcia, Donita C. Brady, Kate Lawrenson, Patrice J. Morin, Ronny Drapkin

Sci Signal. Author manuscript; available in PMC 2022 Oct 5.

Published in final edited form as: Sci Signal. 2022 Apr 5; 15(728): eabm2496. Published online 2022 Apr 5. doi: 10.1126/scisignal.abm2496

PMCID:: PMC9135381

Abstract Article PDF–3.3M

Select item 89853206.

PAX2, PAX8, and PR are correlated with ovarian seromucinous borderline tumor with endometriosis

Bo Seong Yun, Seyeon Won, Ju-Hyun Kim, Nara Lee, Miseon Kim, Mi Kyoung Kim, Mi-La Kim, Yong Wook Jung, Ji Young Kim, Seok Ju Seong, Eunah Shin

J Ovarian Res. 2022; 15: 41. Published online 2022 Apr 6. doi: 10.1186/s13048-022-00975-5

PMCID:: PMC8985320

Abstract Article PDF–1.1M

Select item 88678667.

MiR-326 inhibits trophoblast growth, migration, and invasion by targeting PAX8 via Hippo pathway

Junjie Zang, Min Yan, Yan Zhang, Wei Peng, Jianxin Zuo, Huansheng Zhou, Guoqiang Gao, Min Li, Yijing Chu, Yuanhua Ye

Reprod Biol Endocrinol. 2022; 20: 38. Published online 2022 Feb 24. doi: 10.1186/s12958-022-00909-2

PMCID:: PMC8867866

Abstract Article PDF–6.6M

Select item 88288958.

Human transcription factor protein interaction networks

Helka Göös, Matias Kinnunen, Kari Salokas, Zenglai Tan, Xiaonan Liu, Leena Yadav, Qin Zhang, Gong-Hong Wei, Markku Varjosalo

Nat Commun. 2022; 13: 766. Published online 2022 Feb 9. doi: 10.1038/s41467-022-28341-5

PMCID:: PMC8828895

Abstract Article PDF–1.7M

Select item 88247569.

hsa_circ_0139402 Promotes Bladder Cancer Progression by Regulating hsa-miR-326/PAX8 Signaling

Bo Wei, Zunxian Wang, Qixin Lian, Baojin Chi, Shuxia Ma

Dis Markers. 2022; 2022: 9899548. Published online 2022 Feb 1. doi: 10.1155/2022/9899548

PMCID:: PMC8824756

Abstract Article PDF–1.4M

Select item 829531810.

PAX8 lineage-driven T cell engaging antibody for the treatment of high-grade serous ovarian cancer

Emily Lee, Sarah Szvetecz, Ryan Polli, Angelo Grauel, Jayson Chen, Joyce Judge, Smita Jaiswal, Rie Maeda, Stephanie Schwartz, Bernd Voedisch, Mateusz Piksa, Chietara Japutra, Lingheswar Sadhasivam, Yiqin Wang, Ana Carrion, Sinan Isim, Jinsheng Liang, Thomas Nicholson, Hong Lei, Qing Fang, Michelle Steinkrauss, Dana Walker, Joel Wagner, Viviana Cremasco, Hui Qin Wang, Giorgio G. Galli, Brian Granda, Keith Mansfield, Quincey Simmons, Andrew Anh Nguyen, Nicole Vincent Jordan

Sci Rep. 2021; 11: 14841. Published online 2021 Jul 21. doi: 10.1038/s41598-021-93992-1

PMCID:: PMC8295318

Abstract Article PDF–7.6M

Select item 816503011.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 809397912.

Adipose‐derived mesenchymal stem cells induced PAX8 promotes ovarian cancer cell growth by stabilizing TAZ protein

Yijing Chu, Chengzhan Zhu, Qianqian Wang, Meixin Liu, Wei Wan, Jun Zhou, Rendong Han, Jing Yang, Wenqiang Luo, Chong Liu, Huansheng Zhou, Min Li, Fengsheng Yu, Yuanhua Ye

J Cell Mol Med. 2021 May; 25(9): 4434–4443. Published online 2021 Apr 8. doi: 10.1111/jcmm.16511

PMCID:: PMC8093979

Abstract Article PDF–1.4M

Select item 807622713.

PAX8 and MECOM are interaction partners driving ovarian cancer

Melusine Bleu, Fanny Mermet-Meillon, Verena Apfel, Louise Barys, Laura Holzer, Marianne Bachmann Salvy, Rui Lopes, Inês Amorim Monteiro Barbosa, Cecile Delmas, Alexandra Hinniger, Suzanne Chau, Markus Kaufmann, Simon Haenni, Karolin Berneiser, Maria Wahle, Ivana Moravec, Alexandra Vissières, Tania Poetsch, Erik Ahrné, Nathalie Carte, Johannes Voshol, Elisabeth Bechter, Jacques Hamon, Marco Meyerhofer, Dirk Erdmann, Matteo Fischer, Therese Stachyra, Felix Freuler, Sascha Gutmann, César Fernández, Tobias Schmelzle, Ulrike Naumann, Guglielmo Roma, Kate Lawrenson, Cristina Nieto-Oberhuber, Amanda Cobos-Correa, Stephane Ferretti, Dirk Schübeler, Giorgio Giacomo Galli

Nat Commun. 2021; 12: 2442. Published online 2021 Apr 26. doi: 10.1038/s41467-021-22708-w

PMCID:: PMC8076227

Abstract Article PDF–2.4M

Select item 802650514.

Unraveling the mysteries of PAX8 in reproductive tract cancers

Daniele Chaves-Moreira, Patrice J. Morin, Ronny Drapkin

Cancer Res. Author manuscript; available in PMC 2021 Aug 15.

Published in final edited form as: Cancer Res. 2021 Feb 15; 81(4): 806–810. Published online 2020 Dec 23. doi: 10.1158/0008-5472.CAN-20-3173

PMCID:: PMC8026505

Abstract Article PDF–629K

Select item 800904815.

Impact of cytosine methylation on DNA binding specificities of human transcription factors

Yimeng Yin, Ekaterina Morgunova, Arttu Jolma, Eevi Kaasinen, Biswajyoti Sahu, Syed Khund-Sayeed, Pratyush K. Das, Teemu Kivioja, Kashyap Dave, Fan Zhong, Kazuhiro R. Nitta, Minna Taipale, Alexander Popov, Paul A. Ginno, Silvia Domcke, Jian Yan, Dirk Schübeler, Charles Vinson, Jussi Taipale

Science. Author manuscript; available in PMC 2021 Mar 30.

Published in final edited form as: Science. 2017 May 5; 356(6337): eaaj2239. doi: 10.1126/science.aaj2239

PMCID:: PMC8009048

Abstract Article PDF–2.6M

Select item 800873416.

Genetic variation in cervical preinvasive and invasive disease: a genome-wide association study

Sarah J Bowden, Barbara Bodinier, Ilkka Kalliala, Verena Zuber, Dragana Vuckovic, Triada Doulgeraki, Matthew D Whitaker, Matthias Wielscher, Rufus Cartwright, Konstantinos K Tsilidis, Phillip Bennett, Marjo-Riitta Jarvelin, James M Flanagan, Marc Chadeau-Hyam, Maria Kyrgiou, FinnGen consortium

Lancet Oncol. 2021 Apr; 22(4): 548–557. doi: 10.1016/S1470-2045(21)00028-0

PMCID:: PMC8008734

Abstract Article PDF–13M

Select item 789610417.

Perturbations of genes essential for Müllerian duct and Wölffian duct development in Mayer-Rokitansky-Küster-Hauser syndrome

Na Chen, Sen Zhao, Angad Jolly, Lianlei Wang, Hongxin Pan, Jian Yuan, Shaoke Chen, André Koch, Congcong Ma, Weijie Tian, Ziqi Jia, Jia Kang, Lina Zhao, Chenglu Qin, Xin Fan, Katharina Rall, Zeynep Coban-Akdemir, Zefu Chen, Shalini Jhangiani, Ze Liang, Yuchen Niu, Xiaoxin Li, Zihui Yan, Yong Wu, Shuangshuang Dong, Chengcheng Song, Guixing Qiu, Shuyang Zhang, Pengfei Liu, Jennifer E. Posey, Feng Zhang, Guangnan Luo, Zhihong Wu, Deciphering Disorders Involving Scoliosis and COmorbidities (DISCO) study group, Jianzhong Su, Jianguo Zhang, Eugenia Y. Chen, Konstantinos Rouskas, Stavros Glentis, Flora Bacopoulou, Efthymios Deligeoroglou, George Chrousos, Stanislas Lyonnet, Michel Polak, Carla Rosenberg, Irene Dingeldein, Ximena Bonilla, Christelle Borel, Richard A. Gibbs, Jennifer E. Dietrich, Antigone S. Dimas, Stylianos E. Antonarakis, Sara Y. Brucker, James R. Lupski, Nan Wu, Lan Zhu

Am J Hum Genet. 2021 Feb 4; 108(2): 337–345. Published online 2021 Feb 4. doi: 10.1016/j.ajhg.2020.12.014

PMCID:: PMC7896104

Abstract Article PDF–1.2M

Select item 767912118.

Oncogenic properties and signaling basis of the PAX8-GLIS3 fusion gene

Thais Basili, Higinio Dopeso, Sarah H. Kim, Lorenzo Ferrando, Fresia Pareja, Arnaud Da Cruz Paula, Edaise M. da Silva, Anthe Stylianou, Ana Maroldi, Caterina Marchiò, Brian P. Rubin, Mauro Papotti, Britta Weigelt, Carlos Gil Moreira Ferreira, José Roberto Lapa e Silva, Jorge S. Reis-Filho

Int J Cancer. Author manuscript; available in PMC 2021 Oct 15.

Published in final edited form as: Int J Cancer. 2020 Oct 15; 147(8): 2253–2264. Published online 2020 May 21. doi: 10.1002/ijc.33040

PMCID:: PMC7679121

Abstract Article PDF–2.1M

Select item 744203519.

PAX8-GLIS3 gene fusion is a pathognomonic genetic alteration of hyalinizing trabecular tumors of the thyroid

Caterina Marchiò, Arnaud Da Cruz Paula, Rodrigo Gularte-Merida, Thais Basili, Alissa Brandes, Edaise M. da Silva, Catarina Silveira, Lorenzo Ferrando, Jasna Metovic, Francesca Maletta, Laura Annaratone, Fresia Pareja, Brian P. Rubin, Aaron P. Hoschar, Giovanni De Rosa, Stefano La Rosa, Massimo Bongiovanni, Bibianna Purgina, Simonetta Piana, Marco Volante, Britta Weigelt, Jorge S. Reis-Filho, Mauro Papotti

Mod Pathol. Author manuscript; available in PMC 2020 Dec 1.

Published in final edited form as: Mod Pathol. 2019 Dec; 32(12): 1734–1743. Published online 2019 Jul 4. doi: 10.1038/s41379-019-0313-x

PMCID:: PMC7442035

Abstract Article PDF–2.3M

Select item 726934920.

Pax2 and Pax8 Proteins Regulate Urea Transporters and Aquaporins to Control Urine Concentration in the Adult Kidney

Ann M. Laszczyk, Atsuko Y. Higashi, Sanjeevkumar R. Patel, Craig N. Johnson, Abdul Soofi, Saji Abraham, Gregory R. Dressler

J Am Soc Nephrol. 2020 Jun; 31(6): 1212–1225. Published online 2020 May 7. doi: 10.1681/ASN.2019090962

PMCID:: PMC7269349

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