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Select item 112002721.

Nrg1 intracellular signaling regulates the development of interhemispheric callosal axons in mice

Ángela Rodríguez-Prieto, Isabel Mateos-White, Mar Aníbal-Martínez, Carmen Navarro-González, Cristina Gil-Sanz, Yaiza Domínguez-Canterla, Ana González-Manteiga, Verónica Del Buey Furió, Guillermina López-Bendito, Pietro Fazzari

Life Sci Alliance. 2024 Sep; 7(9): e202302250. Published online 2024 Jun 25. doi: 10.26508/lsa.202302250

PMCID:: PMC11200272

Abstract Article PDF–2.6M

Select item 111564122.

Malic enzyme 1 knockout has no deleterious phenotype and is favored in the male germline under standard laboratory conditions

Jonathan M. Alektiar, Mengrou Shan, Megan D. Radyk, Li Zhang, Christopher J. Halbrook, Lin Lin, Carlos Espinoza, Ivan F. Mier, Brooke L. Lavoie, Lucie Salvatore, Marina Pasca di Magliano, Lewis C. Cantley, Jacob L. Mueller, Costas A. Lyssiotis

PLoS One. 2024; 19(6): e0303577. Published online 2024 Jun 6. doi: 10.1371/journal.pone.0303577

PMCID:: PMC11156412

Abstract Article PDF–2.1M

Select item 111481223.

Conditional deficiency of Rho‐associated kinases disrupts endothelial cell junctions and impairs respiratory function in adult mice

Takahiro Akamine, Takeshi Terabayashi, Takako Sasaki, Riku Hayashi, Ichitaro Abe, Fumihiro Hirayama, Shin‐ichi Nureki, Masahito Ikawa, Haruhiko Miyata, Akinori Tokunaga, Takashi Kobayashi, Katsuhiro Hanada, Dean Thumkeo, Shuh Narumiya, Toshimasa Ishizaki

FEBS Open Bio. 2024 Jun; 14(6): 906–921. Published online 2024 Apr 11. doi: 10.1002/2211-5463.13802

PMCID:: PMC11148122

Abstract Article PDF–12M

Select item 110936124.

Excess glucocorticoids inhibit murine bone turnover via modulating the immunometabolism of the skeletal microenvironment

Xu Li, Tongzhou Liang, Bingyang Dai, Liang Chang, Yuan Zhang, Shiwen Hu, Jiaxin Guo, Shunxiang Xu, Lizhen Zheng, Hao Yao, Hong Lian, Yu Nie, Ye Li, Xuan He, Zhi Yao, Wenxue Tong, Xinluan Wang, Dick Ho Kiu Chow, Jiankun Xu, Ling Qin

J Clin Invest. 2024 May 15; 134(10): e166795. Published online 2024 Mar 21. doi: 10.1172/JCI166795

PMCID:: PMC11093612

Abstract Article PDF–27M

Select item 110812245.

ΔNp63 regulates Sfrp1 expression to direct salivary gland branching morphogenesis

Theresa Wrynn, Sangwon Min, Erich Horeth, Jason Osinski, Satrajit Sinha, Rose-Anne Romano

PLoS One. 2024; 19(5): e0301082. Published online 2024 May 9. doi: 10.1371/journal.pone.0301082

PMCID:: PMC11081224

Abstract Article PDF–7.0M

Select item 110228866.

Viable mutations of mouse midnolin suppress B cell malignancies

Xue Zhong, Nagesh Peddada, James J. Moresco, Jianhui Wang, Yiao Jiang, Jonathan J. Rios, Eva Marie Y. Moresco, Jin Huk Choi, Bruce Beutler

J Exp Med. 2024 Jun 3; 221(6): e20232132. Published online 2024 Apr 16. doi: 10.1084/jem.20232132

PMCID:: PMC11022886

Abstract Article PDF–7.7M

Select item 109495767.

Cre-LoxP and tamoxifen-induced deletion of ovarian quiescin sulfhydryl oxidase 2 showed disruption of ovulatory activity in mice

Shih-Yun Chen, Tse-En Wang, Wei-Yun Lee, Ya-Yi Yang, Hong-Chun Lai, Fuko Matsuda, Haruhiko Kosek, You-Tzung Chen, Sheng-Hsiang Li, Pei-Shiue Tsai

J Ovarian Res. 2024; 17: 66. Published online 2024 Mar 19. doi: 10.1186/s13048-024-01388-2

PMCID:: PMC10949576

Abstract Article PDF–6.8M

Select item 109436468.

Differential depletion of GluN2A induces heterogeneous schizophrenia-related phenotypes in mice

Yi Lu, Longyu Mu, Justin Elstrott, Chaoying Fu, Cailu Sun, Tonghui Su, Xiaofan Ma, Jia Yan, Hong Jiang, Jesse E. Hanson, Yang Geng, Yelin Chen

eBioMedicine. 2024 Apr; 102: 105045. Published online 2024 Mar 11. doi: 10.1016/j.ebiom.2024.105045

PMCID:: PMC10943646

Abstract Article PDF–2.1M

Select item 108226699.

Reprogramming of tumor-associated macrophages via NEDD4-mediated CSF1R degradation by targeting USP18

Sayuri Miyauchi, Kei-ichiro Arimoto, Mengdan Liu, Yue Zhang, Dong-Er Zhang

Cell Rep. Author manuscript; available in PMC 2024 Jan 28.

Published in final edited form as: Cell Rep. 2023 Dec 26; 42(12): 113560. Published online 2023 Dec 13. doi: 10.1016/j.celrep.2023.113560

PMCID:: PMC10822669

Abstract Article PDF–2.5M

Select item 1080781510.

Endogenous retroviruses shape pluripotency specification in mouse embryos

Sergio de la Rosa, María del Mar Rigual, Pierfrancesco Vargiu, Sagrario Ortega, Nabil Djouder

Sci Adv. 2024 Jan 26; 10(4): eadk9394. Published online 2024 Jan 24. doi: 10.1126/sciadv.adk9394

PMCID:: PMC10807815

Abstract Article PDF–23M

Select item 1075026811.

Microenvironmental CXCL12 Deletion Enhances Flt3-ITD Acute Myeloid Leukemia Stem Cell Response to Therapy by Reducing p38 MAPK Signaling

Nicholas R. Anderson, Vipul Sheth, Hui Li, Mason W. Harris, Shaowei Qiu, David K. Crossman, Harish Kumar, Puneet Agarwal, Takashi Nagasawa, Andrew J. Paterson, Robert S. Welner, Ravi Bhatia

Leukemia. Author manuscript; available in PMC 2023 Dec 26.

Published in final edited form as: Leukemia. 2023 Mar; 37(3): 560–570. Published online 2022 Dec 22. doi: 10.1038/s41375-022-01798-5

PMCID:: PMC10750268

Abstract Article PDF–1.3M

Select item 1071615512.

Late gene therapy limits the restoration of retinal function in a mouse model of retinitis pigmentosa

Miranda L. Scalabrino, Mishek Thapa, Tian Wang, Alapakkam P. Sampath, Jeannie Chen, Greg D. Field

Nat Commun. 2023; 14: 8256. Published online 2023 Dec 12. doi: 10.1038/s41467-023-44063-8

PMCID:: PMC10716155

Abstract Article PDF–3.1M

Select item 1062489913.

Spliceosome component Usp39 contributes to hepatic lipid homeostasis through the regulation of autophagy

Donghai Cui, Zixiang Wang, Qianli Dang, Jing Wang, Junchao Qin, Jianping Song, Xiangyu Zhai, Yachao Zhou, Ling Zhao, Gang Lu, Hongbin Liu, Gang Liu, Runping Liu, Changshun Shao, Xiyu Zhang, Zhaojian Liu

Nat Commun. 2023; 14: 7032. Published online 2023 Nov 3. doi: 10.1038/s41467-023-42461-6

PMCID:: PMC10624899

Abstract Article PDF–7.0M

Select item 1057813414.

Dysregulated tissue niche potentiates resident lymphocytes to suppress an interferon-sensitive stem cell reservoir in emphysema

Chaoqun Wang, Benjamin Hyams, Nancy C. Allen, Kelly Cautivo, Kiara Monahan, Minqi Zhou, Madelene W. Dahlgren, Carlos O. Lizama, Michael Matthay, Paul Wolters, Ari B. Molofsky, Tien Peng

Immunity. Author manuscript; available in PMC 2024 Mar 14.

Published in final edited form as: Immunity. 2023 Mar 14; 56(3): 576–591.e10. Published online 2023 Feb 22. doi: 10.1016/j.immuni.2023.01.032

PMCID:: PMC10578134

Abstract Article PDF–5.0M

Select item 1057589215.

PPTC7 maintains mitochondrial protein content by suppressing receptor-mediated mitophagy

Natalie M. Niemi, Lia R. Serrano, Laura K. Muehlbauer, Catherine E. Balnis, Lianjie Wei, Andrew J. Smith, Keri-Lyn Kozul, Merima Forny, Olivia M. Connor, Edrees H. Rashan, Evgenia Shishkova, Kathryn L. Schueler, Mark P. Keller, Alan D. Attie, Jonathan R. Friedman, Julia K. Pagan, Joshua J. Coon, David J. Pagliarini

Nat Commun. 2023; 14: 6431. Published online 2023 Oct 13. doi: 10.1038/s41467-023-42069-w

PMCID:: PMC10575892

Abstract Article PDF–4.0M

Select item 1051722516.

Themis controls T cell activation, effector functions, and metabolism of peripheral CD8⁺ T cells

Namrata Gautam, Lukasz Wojciech, Jiawei Yap, Yen Leong Chua, Eyan MW Ding, Don CN Sim, Alrina SM Tan, Patricia J Ahl, Mukul Prasad, Desmond WH Tung, John E Connolly, Giulia Adriani, Joanna Brzostek, Nicholas RJ Gascoigne

Life Sci Alliance. 2023 Dec; 6(12): e202302156. Published online 2023 Sep 22. doi: 10.26508/lsa.202302156

PMCID:: PMC10517225

Abstract Article PDF–3.4M

Select item 1047664317.

Bace1 Deletion in the Adult Reverses Epileptiform Activity and Sleep–wake Disturbances in AD Mice

Annie Y. Yao, Patrick J. Halloran, Yingying Ge, Neeraj Singh, John Zhou, James Galske, Wanxia He, Riqiang Yan, Xiangyou Hu

J Neurosci. 2023 Aug 30; 43(35): 6197–6211. doi: 10.1523/JNEUROSCI.2124-22.2023

PMCID:: PMC10476643

Abstract Article PDF–3.9M

Select item 1047396118.

Microenvironmental Snail1-induced immunosuppression promotes melanoma growth

Marta Arumi-Planas, Francisco Javier Rodriguez-Baena, Francisco Cabello-Torres, Francisco Gracia, Cristina Lopez-Blau, M. Angela Nieto, Berta Sanchez-Laorden

Oncogene. 2023; 42(36): 2659–2672. Published online 2023 Jul 29. doi: 10.1038/s41388-023-02793-5

PMCID:: PMC10473961

Abstract Article PDF–3.9M

Select item 1038209019.

Adenosine A_2A Receptor Regulates microRNA‐181b Expression in Aorta: Therapeutic Implications for Large‐Artery Stiffness

Kei Akiyoshi, Tomonari Fujimori, Xiuping Fu, Aparna P. Shah, Atsushi Yamaguchi, Charles Steenbergen, Lakshmi Santhanam, Dan Berkowitz, Eric Tuday, Jay M. Baraban, Samarjit Das

J Am Heart Assoc. 2023 Jul 18; 12(14): e028421. Published online 2023 Jul 8. doi: 10.1161/JAHA.122.028421

PMCID:: PMC10382090

Abstract Article PDF–1.7M

Select item 1031336720.

The SWI/SNF chromatin-remodeling subunit DPF2 facilitates NRF2-dependent antiinflammatory and antioxidant gene expression

Gloria Mas, Na Man, Yuichiro Nakata, Concepcion Martinez-Caja, Daniel Karl, Felipe Beckedorff, Francesco Tamiro, Chuan Chen, Stephanie Duffort, Hidehiro Itonaga, Adnan K. Mookhtiar, Kranthi Kunkalla, Alfredo M. Valencia, Clayton K. Collings, Cigall Kadoch, Francisco Vega, Scott C. Kogan, Ramin Shiekhattar, Lluis Morey, Daniel Bilbao, Stephen D. Nimer

J Clin Invest. 2023 Jul 3; 133(13): e158419. Published online 2023 Jul 3. doi: 10.1172/JCI158419

PMCID:: PMC10313367

Abstract Article PDF–13M

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